MX2009003042A - Composiciones farmaceuticas acuosas auto-preservadas. - Google Patents

Composiciones farmaceuticas acuosas auto-preservadas.

Info

Publication number
MX2009003042A
MX2009003042A MX2009003042A MX2009003042A MX2009003042A MX 2009003042 A MX2009003042 A MX 2009003042A MX 2009003042 A MX2009003042 A MX 2009003042A MX 2009003042 A MX2009003042 A MX 2009003042A MX 2009003042 A MX2009003042 A MX 2009003042A
Authority
MX
Mexico
Prior art keywords
self
pharmaceutical compositions
compositions
aqueous pharmaceutical
preserved
Prior art date
Application number
MX2009003042A
Other languages
English (en)
Inventor
Masood A Chowhan
David J Keith
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39144554&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009003042(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of MX2009003042A publication Critical patent/MX2009003042A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Se describe el uso de un sistema de borato/poliol y zinc para mejorar la actividad antimicrobiana de composiciones farmacéuticas, multidosis. Las composiciones no requieren un preservativo anti-microbiano, convencional, y por lo tanto se mencionan como `auto-preservadas´. Las composiciones poseen suficiente actividad antimicrobiana para satisfacer los requerimientos de eficacia de preservativos de la USP para composiciones oftálmicas, acuosas.
MX2009003042A 2006-09-28 2007-09-20 Composiciones farmaceuticas acuosas auto-preservadas. MX2009003042A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82741706P 2006-09-28 2006-09-28
PCT/US2007/079094 WO2008042619A2 (en) 2006-09-28 2007-09-20 Self-preserved aqueous pharmaceutical compositions

Publications (1)

Publication Number Publication Date
MX2009003042A true MX2009003042A (es) 2009-04-02

Family

ID=39144554

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009003042A MX2009003042A (es) 2006-09-28 2007-09-20 Composiciones farmaceuticas acuosas auto-preservadas.

Country Status (14)

Country Link
US (1) US8388941B2 (es)
EP (1) EP2066300B2 (es)
JP (2) JP5394927B2 (es)
KR (1) KR101421519B1 (es)
CN (1) CN101522171A (es)
AU (1) AU2007304996B2 (es)
BR (1) BRPI0717093A2 (es)
CA (1) CA2663817A1 (es)
ES (1) ES2543349T5 (es)
HK (1) HK1126419A1 (es)
MX (1) MX2009003042A (es)
PL (1) PL2066300T5 (es)
WO (1) WO2008042619A2 (es)
ZA (1) ZA200901702B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101522171A (zh) 2006-09-28 2009-09-02 爱尔康研究有限公司 自身防腐的水性药物组合物
TWI544927B (zh) 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
TWI489997B (zh) 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸－多元醇錯合物之水性藥學組成物
JP6313599B2 (ja) 2011-11-01 2018-04-18 ロート製薬株式会社 眼科用水性組成物
JP6313598B2 (ja) * 2011-11-01 2018-04-18 ロート製薬株式会社 眼科用水性組成物
EP2630952A1 (en) 2012-02-23 2013-08-28 Novagali Pharma S.A. Self-preserved oil dispersions comprising boric acid
GB201211702D0 (en) 2012-07-02 2012-08-15 Reckitt Benckiser Llc Sprayable aqueous alcoholic microbicidal compostions comprising zinc ions
GB201211701D0 (en) 2012-07-02 2012-08-15 Reckitt Benckiser Llc Aqueous alcoholic microbicidal compositions comprising zinc ions
JP6027866B2 (ja) * 2012-11-22 2016-11-16 ロート製薬株式会社 オロパタジン含有水性組成物
EP2925125A1 (en) 2012-11-30 2015-10-07 Reckitt & Colman (Overseas) Limited Microbicidal personal care compositions comprising metal ions
RU2675813C2 (ru) * 2013-02-15 2018-12-25 Сэндзю Фармацевтикал Ко., Лтд. Эмульсионная композиция дифлупредната, содержащая цинк
US9693563B2 (en) 2013-08-20 2017-07-04 3M Innovative Properties Company Boron-silane polyether complex
CN106456667B (zh) * 2014-06-24 2022-04-19 3M创新有限公司 低发泡多酶清洁剂
US11458041B2 (en) 2015-10-08 2022-10-04 Ocular Therapeutix, Inc. Punctal plug and bioadhesives
KR20220151622A (ko) 2020-02-06 2022-11-15 오큘라 테라퓨틱스, 인코포레이티드 안질환 치료를 위한 조성물 및 방법

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2084870B (en) 1980-10-10 1985-05-09 Muhlemann R Hans Oral compositions containing pyrimidine amine compounds and zinc salts
US5607698A (en) 1988-08-04 1997-03-04 Ciba-Geigy Corporation Method of preserving ophthalmic solution and compositions therefor
IL92351A (en) 1988-11-29 1994-02-27 Allergan Inc Irvine Optimal aqueous solutions containing stabilized chlorine acid and inorganic salt
US5130298A (en) 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
US5221664A (en) 1990-04-23 1993-06-22 Magainin Pharmaaceuticals Inc. Composition and treatment with biologically active peptides and toxic cations
UA26334A (uk) 1990-12-27 1999-08-30 Еллергаh Іhк. Спосіб дезиhфекції коhтактhих ліhз та композиція для дезиhфекції коhтактhих ліhз
US5460834A (en) 1991-12-13 1995-10-24 Alcon Laboratories, Inc. Combinations of polymers for use in physiological tear compositions
DK0639070T4 (da) 1992-05-06 2010-12-13 Alcon Lab Inc Anvendelse af borat-polyolkomplekser til ophtalmiske præparater
US5505953A (en) * 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
US5352708A (en) 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5320843A (en) 1992-12-10 1994-06-14 Polymer Technology Corporation Method for improving antibacterial properties of ophthalmic solutions
US5736165A (en) 1993-05-25 1998-04-07 Allergan In-the-eye use of chlorine dioxide-containing compositions
TW274516B (es) 1993-11-12 1996-04-21 Ciba Geigy Ag
WO1996003158A1 (en) 1994-07-22 1996-02-08 Alcon Laboratories, Inc. Use of low molecular weight amino acids in ophthalmic compositions
US6024954A (en) 1994-12-12 2000-02-15 Allergan Compositions and methods for disinfecting contact lenses and preserving contact lens care products
CN1074277C (zh) 1995-03-20 2001-11-07 尤尼利弗公司 液体洁肤制剂
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HU225329B1 (en) 1996-09-12 2006-09-28 Richter Gedeon Vegyeszet Use of zinc or cobalt hyaluronate associate for the manufacture of pharmaceutical compositions of antimicrobial activity
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US5820822A (en) 1996-10-25 1998-10-13 Kross; Robert D. Antimicrobial composition and method of use
DE69713388T2 (de) 1996-12-13 2002-10-31 Alcon Lab Inc Verwendung von niedermolekularen aminoalkoholen in ophthalmologischen präparaten
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CA2296080C (en) 1997-07-29 2005-02-01 Alcon Laboratories, Inc. Ophthalmic compositions containing galactomannan polymers and borate
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TW496745B (en) 2000-11-29 2002-08-01 Novartis Ag Aqueous disinfecting systems
AR035509A1 (es) * 2000-12-21 2004-06-02 Alcon Inc Solucion de lagrimas artificiales mejorada que contiene una combinacion de tres emolientes y el uso de dicha solucion para la fabricacion de un medicamento
JP4863589B2 (ja) 2001-09-28 2012-01-25 ロート製薬株式会社 水性組成物
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JP4644682B2 (ja) 2003-12-09 2011-03-02 アルコン、インコーポレイテッド 水性組成物の抗微生物活性を強化するためのビスアミンの使用
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US20050214382A1 (en) * 2004-03-29 2005-09-29 Erning Xia Zinc preservative composition and method of use
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TWI394564B (zh) 2006-09-21 2013-05-01 Alcon Res Ltd 自行保存型水性藥學組成物
CN101522171A (zh) 2006-09-28 2009-09-02 爱尔康研究有限公司 自身防腐的水性药物组合物

Also Published As

Publication number Publication date
EP2066300A2 (en) 2009-06-10
WO2008042619A2 (en) 2008-04-10
PL2066300T3 (pl) 2015-10-30
KR101421519B1 (ko) 2014-07-30
WO2008042619A3 (en) 2008-07-03
KR20090066308A (ko) 2009-06-23
ES2543349T3 (es) 2015-08-18
HK1126419A1 (en) 2009-09-04
AU2007304996A1 (en) 2008-04-10
US20100021562A1 (en) 2010-01-28
JP5394927B2 (ja) 2014-01-22
AU2007304996B2 (en) 2013-03-21
CA2663817A1 (en) 2008-04-10
JP2013234199A (ja) 2013-11-21
BRPI0717093A2 (pt) 2013-11-26
EP2066300B2 (en) 2019-01-23
US8388941B2 (en) 2013-03-05
JP2010504990A (ja) 2010-02-18
EP2066300B1 (en) 2015-06-17
ES2543349T5 (es) 2019-06-17
ZA200901702B (en) 2010-06-30
PL2066300T5 (pl) 2020-03-31
CN101522171A (zh) 2009-09-02

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