MX2009001977A - Derivados profarmacologicos de aminoacilo y medicamentos para el tratamiento de enfermedades tromboembolicas. - Google Patents
Derivados profarmacologicos de aminoacilo y medicamentos para el tratamiento de enfermedades tromboembolicas.Info
- Publication number
- MX2009001977A MX2009001977A MX2009001977A MX2009001977A MX2009001977A MX 2009001977 A MX2009001977 A MX 2009001977A MX 2009001977 A MX2009001977 A MX 2009001977A MX 2009001977 A MX2009001977 A MX 2009001977A MX 2009001977 A MX2009001977 A MX 2009001977A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- medicaments
- prodrug derivatives
- thromboembolic disorders
- aminoacyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La presente solicitud se refiere a derivados profarmacológicos de 5-cloro-N-({(5S)-2-oxo-3-[4-(3-oxomorfolin-4-il)fenil]-1,3-oxazol idin-5-il}metil)tiofen-2-carboxamida, a procedimientos para su preparación, su uso para el tratamiento y/o prevención de enfermedades, así como su uso para producir medicamentos para el tratamiento y/o la prevención de enfermedades, en especial de enfermedades tromboembólicas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006039589A DE102006039589A1 (de) | 2006-08-24 | 2006-08-24 | Aminoacyl-Prodrugs II |
PCT/EP2007/007408 WO2008022786A1 (de) | 2006-08-24 | 2007-08-23 | Aminoacyl-prodrug derivate und arzneimittel zur behandlung von thromboembolischen erkrankungen |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009001977A true MX2009001977A (es) | 2009-05-21 |
Family
ID=38694946
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009001977A MX2009001977A (es) | 2006-08-24 | 2007-08-23 | Derivados profarmacologicos de aminoacilo y medicamentos para el tratamiento de enfermedades tromboembolicas. |
Country Status (16)
Country | Link |
---|---|
US (1) | US8362015B2 (es) |
EP (1) | EP2084154B1 (es) |
JP (1) | JP5352461B2 (es) |
KR (1) | KR20090057266A (es) |
CN (1) | CN101547921B (es) |
AU (1) | AU2007287749B2 (es) |
BR (1) | BRPI0715741A2 (es) |
CA (1) | CA2661414C (es) |
DE (1) | DE102006039589A1 (es) |
ES (1) | ES2399069T3 (es) |
HK (1) | HK1137987A1 (es) |
IL (1) | IL197079A0 (es) |
MX (1) | MX2009001977A (es) |
RU (1) | RU2456283C9 (es) |
WO (1) | WO2008022786A1 (es) |
ZA (1) | ZA200901189B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102006007146A1 (de) * | 2006-02-16 | 2007-08-23 | Bayer Healthcare Ag | Aminoacyl-Prodrugs |
DE102007028319A1 (de) * | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
DE102007028407A1 (de) * | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
US7816355B1 (en) | 2009-04-28 | 2010-10-19 | Apotex Pharmachem Inc | Processes for the preparation of rivaroxaban and intermediates thereof |
DE102010028362A1 (de) | 2010-04-29 | 2011-11-03 | Bayer Schering Pharma Aktiengesellschaft | Herstellverfahren |
EP2630143B1 (en) * | 2010-10-18 | 2017-11-29 | Apotex Pharmachem Inc. | Processes for the preparation of rivaroxaban and intermediates thereof |
CA2883323A1 (en) * | 2012-12-26 | 2014-07-03 | Wanbury Ltd. | Aldehyde derivative of substituted oxazolidinones |
JP6998780B2 (ja) | 2018-02-02 | 2022-01-18 | 株式会社デンソー | 冷凍サイクル装置 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7425541B2 (en) * | 1998-12-11 | 2008-09-16 | Medarex, Inc. | Enzyme-cleavable prodrug compounds |
PT1196414E (pt) * | 1999-06-25 | 2003-12-31 | Vertex Pharma | Pro-farmacos de inibidores carbamato de impdh |
DE19962924A1 (de) * | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
TW591024B (en) * | 2000-03-27 | 2004-06-11 | Sankyo Lifetech Company Ltd | An amide type triazole compound having antifungal activity |
DE10129725A1 (de) * | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
CA2452513A1 (en) | 2001-07-12 | 2003-01-23 | Pharmacia & Upjohn Company | Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound |
JP3630326B2 (ja) * | 2002-08-22 | 2005-03-16 | 三共株式会社 | 水溶性トリアゾール医薬組成物 |
US7265140B2 (en) * | 2003-09-23 | 2007-09-04 | Pfizer Inc | Acyloxymethylcarbamate prodrugs of oxazolidinones |
DE10355461A1 (de) * | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
DE102004002044A1 (de) * | 2004-01-15 | 2005-08-04 | Bayer Healthcare Ag | Herstellverfahren |
EP1893572B1 (en) * | 2004-06-18 | 2016-12-14 | Millennium Pharmaceuticals, Inc. | Factor xa inhibitors |
WO2006017351A1 (en) * | 2004-07-12 | 2006-02-16 | Xenoport, Inc. | Prodrugs of propofol, compositions and uses thereof |
DE102004062475A1 (de) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
DE102005047558A1 (de) * | 2005-10-04 | 2008-02-07 | Bayer Healthcare Ag | Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen |
DE102006007146A1 (de) * | 2006-02-16 | 2007-08-23 | Bayer Healthcare Ag | Aminoacyl-Prodrugs |
DE102006025314A1 (de) * | 2006-05-31 | 2007-12-06 | Bayer Healthcare Ag | Arylsubstituierte Heterozyklen und ihre Verwendung |
DE102007028407A1 (de) * | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
DE102007028319A1 (de) * | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
DE102007028406A1 (de) * | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
-
2006
- 2006-08-24 DE DE102006039589A patent/DE102006039589A1/de not_active Withdrawn
-
2007
- 2007-08-23 ES ES07801837T patent/ES2399069T3/es active Active
- 2007-08-23 KR KR1020097005866A patent/KR20090057266A/ko not_active Application Discontinuation
- 2007-08-23 JP JP2009524961A patent/JP5352461B2/ja not_active Expired - Fee Related
- 2007-08-23 US US12/438,097 patent/US8362015B2/en not_active Expired - Fee Related
- 2007-08-23 WO PCT/EP2007/007408 patent/WO2008022786A1/de active Application Filing
- 2007-08-23 CN CN200780039838.XA patent/CN101547921B/zh not_active Expired - Fee Related
- 2007-08-23 EP EP07801837A patent/EP2084154B1/de active Active
- 2007-08-23 AU AU2007287749A patent/AU2007287749B2/en not_active Expired - Fee Related
- 2007-08-23 RU RU2009110246/04A patent/RU2456283C9/ru not_active IP Right Cessation
- 2007-08-23 BR BRPI0715741-0A patent/BRPI0715741A2/pt not_active IP Right Cessation
- 2007-08-23 MX MX2009001977A patent/MX2009001977A/es active IP Right Grant
- 2007-08-23 CA CA2661414A patent/CA2661414C/en not_active Expired - Fee Related
-
2009
- 2009-02-17 IL IL197079A patent/IL197079A0/en unknown
- 2009-02-19 ZA ZA200901189A patent/ZA200901189B/xx unknown
-
2010
- 2010-03-26 HK HK10103172.2A patent/HK1137987A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US8362015B2 (en) | 2013-01-29 |
AU2007287749B2 (en) | 2013-09-12 |
ZA200901189B (en) | 2010-04-28 |
KR20090057266A (ko) | 2009-06-04 |
ES2399069T3 (es) | 2013-03-25 |
CN101547921B (zh) | 2015-01-07 |
CA2661414C (en) | 2015-04-28 |
EP2084154A1 (de) | 2009-08-05 |
HK1137987A1 (en) | 2010-08-13 |
RU2009110246A (ru) | 2010-09-27 |
RU2456283C2 (ru) | 2012-07-20 |
DE102006039589A1 (de) | 2008-03-06 |
BRPI0715741A2 (pt) | 2013-07-16 |
RU2456283C9 (ru) | 2013-05-10 |
US20100292230A1 (en) | 2010-11-18 |
CA2661414A1 (en) | 2008-02-28 |
JP2010501504A (ja) | 2010-01-21 |
CN101547921A (zh) | 2009-09-30 |
WO2008022786A1 (de) | 2008-02-28 |
AU2007287749A1 (en) | 2008-02-28 |
JP5352461B2 (ja) | 2013-11-27 |
EP2084154B1 (de) | 2012-11-21 |
IL197079A0 (en) | 2009-11-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
GB | Transfer or rights |