MX2008006803A - Use of a composition comprising pentane-1, 5-diol as deodorant - Google Patents

Abstract

The present invention relates to the use of a composition comprising pentane-1, 5-diol to reduce and/or eliminate odour from a mammal, such as odour from such as urine, faeces, liquids from leg ulcers, decubital ulcers, blood and perspiration. The invention also relates to absorbent and/or sanitary products comprising pentane-1, 5- diol.

Description

USE AS A DEODORANT OF A COMPOSITION COMPRISING PENTANE-1,5-DIOL FIELD OF THE INVENTION The present invention relates to the use of a composition for reducing and / or eliminating the odor of a mammal, such as the odor of urine, feces, liquid ulcers on the legs, pressure ulcers in the decubitus position, blood and perspiration. The invention also relates to absorbent and / or sanitary products.

BACKGROUND OF THE INVENTION Currently, the human being is using a large amount of disposable products such as sanitary napkins and diapers in which these products for use with humans are contaminated with different body fluids such as urine, feces, ulcer fluids. in the legs, ulcers due to decubitus position, blood and perspiration. Therefore the product and the human being who use said product begin to smell. When odor emission has occurred, the only possibility to reduce and / or eliminate odor is to dispose of and dispose of the disposable product. All disposable products, which are discarded, increase the pressure in the environment. This can mean that the human being, when consuming a REF product. : 193241 disposable to absorb, for example urine, can change the disposable product several times each day to eliminate when odor occurs, which is not very pleasant for the surrounding environment or the consumer itself. The same applies to older people in institutions as well as in hospitals. If a disposable product is available on the market which has improved new properties, for example with the ability to reduce and / or eliminate the odor of human liquids, it can be an improvement for the human consumer as well as for the environment, where the consumer human can feel safe and that no odors are produced by leaks or for example by urine or perspiration. In addition, the costs can be reduced for the consumer since there is no need to change the disposable product so frequently. Therefore, there is a need for a new disposable product that meets the demands of reducing and / or eliminating the odor of liquids from human beings, disposable product by means of which the costs for the consumer are reduced and also the pressure in the consumer is reduced. the environment of disposable products. WO 02/064177 discloses a disposable absorbent article comprising an absorbent body and a cover enclosing it, which cover may be impregnated with 2-methyl-2, -pentanediol or propylene glycol. The 2-methyl-2,4-pentanediol or propylene glycol is applied to the coating to improve absorption in this hydrophobic layer. In this way, nothing is mentioned about the use of 2-methyl-2, -pentanediol or propylene glycol to reduce odor and a second substance, lactic acid, in fact added to reduce odor. In fact, 2-methyl-2,4-pentanediol is highly unsatisfactory with respect to providing an effect against odors since this substance has a strong odor by itself. Propylene glycol has moderate activity as an antimicrobial agent and will therefore only be moderately effective in reducing odors. WO 03/092757 discloses a flexible absorbent sheet material which may comprise a plasticizer, such as 1,3-propanediol or 1,4-butanediol. Nothing is mentioned about using a diol to obtain an effect against odor. Rather, the diols mentioned are used only to alter the mechanical properties of the sheet. In fact, 1,4-butanediol is not suitable for use with high yields in relation to the human body since it metabolizes to? -hydroxyl butyrate (GHB), a substance which affects the human body in a very negative and toxic way . Both 1,3-propanediol and 1-butanediol are moderately active as antimicrobial agents, due to their slightly short length of carbon chain and therefore will only be moderately effective in reducing odors.

EP 0044543 describes a topical pharmaceutical formulation comprising a water-miscible polyhydric alcohol. In EP 0044543 propylene glycol, butane-1,3-diol, polyethylene glycol and glycerol are preferred, wherein propylene glycol, such as polyhydric alcohol, is especially preferred. EP 0044543 does not disclose which polyhydric alcohols can be provided with an effect against odor, whereby EP 0044543 also naturally fails to differentiate between different polyhydric alcohols with respect to their suitability as agents to obtain an effect against odors. The polyhydric alcohols mentioned as being preferred and especially preferred are only moderately active as antimicrobial agents due to their rather short length of carbon chain and therefore will only be moderately effective in reducing odor. JP 2003081801 discloses 1, 2-alkanediols such as 1,2-pentanediol, 1,2-hexanediol and 1,2-octanediol, to prevent body odor. However, these diols are not very suitable for use as anti-odor agents since they have strong odors by themselves. The 1,2-pentanediol has, for example, an aromatic odor which alters the comfort of the consumer in a negative way. In addition, 1,2-hexanediol and 1,2-octanediol have little solubility in body fluids such as urine. In addition, these diols are expensive which returns to the products obtained by using the expensive diols. Other documents describing similar compositions for use as an anti-odor agent are JP 19920319931 and JP 2001190647. Therefore, an advantageous way to obtain an effect against odor in absorbent products would be advantageous and in particular a method for reducing and / or eliminate the odor of a mammal, such as the smell of urine, feces, leg ulcer fluids, position ulcers in decubitus, blood and transpiration, which method does not generate other smells or aromas that may be uncomfortable for the consumer, method which is profitable and method which does not need to use other substances that hide odors such as perfumes which can generate allergies and / or method which does not involve the simultaneous coloring of products, can be advantageous. In addition, the products obtained by said method and the compositions used in the methods can be advantageous.

BRIEF DESCRIPTION OF THE INVENTION Accordingly, the present invention preferably seeks to mitigate, alleviate or eliminate one or more of the deficiencies identified in the foregoing in the art and the disadvantages alone or in any combination and resolves at least the above mentioned problems when supplying the use of a composition comprising pentane-1,5-diol to reduce and / or eliminate the odor of a mammal such as urine odor, feces, leg ulcer liquids, decubitus position ulcers, blood and transpiration , an absorption product comprising pentane-1,5-diol to reduce and / or eliminate the odor of a mammal such as urine odor, feces, leg ulcer fluids, decubitus position ulcers, blood and perspiration. By means of the invention, the human being who uses the composition does not suffer from the odor that the body fluid that comes from the human being is normally generated. The composition can be integrated / applied onto an absorbent and / or sanitary article and in this way the odor of the mammal is reduced and / or eliminated by use of the article. The invention also relates to a package comprising one or more absorbent and / or sanitary articles as mentioned in the above.

DETAILED DESCRIPTION OF THE INVENTION In the context of the present invention the following definitions apply: The term "article" and "product" within the application is understood to mean the same. The term "odor" is meant to mean any odor that may arise from bodily fluids coming from a mammal such as a human being. Examples of body fluids are such as urine, stools, leg ulcer fluids, position ulcers in decubitus, blood and perspiration as well as menstruation. The term "absorbent product" is intended to mean any product that can absorb human liquids such as bandages or compresses. The term "sanitary product" is intended to mean any product that can be used, at least partially, to absorb urine, menstruation and / or feces. Examples are sprays, deodorants, diapers and tampons. Use of a diol to reduce odor The invention relates to the use of a composition comprising pentane-1,5-d-ol to reduce and / or eliminate the odor of a mammal such as the odor of urine, feces, liquids of ulcers on the legs, ulcers due to lying, blood, menstruation and perspiration. By the invented use of pentane-1, 5-d? Ol to reduce and / or eliminate the odor several problems have been solved in such a way that the consumer no longer suffers from the odor and there is no need to change, for example a diaper so frequently and in such a way that the costs of diaper use are reduced. The use of pentane-1,5-d-ol to reduce and / or eliminate the odor of a mammal such as the smell of urine, feces, leg ulcer liquids, decubitus ulcers, blood and perspiration provides several advantages over to the diols used in the prior art. First, pentane-1,5-diol is odorless which gives pentane-1,5-diol a great advantage compared to many other diols, especially in providing an anti-odor effect. Here, when pentane-1, 5-diol is used to reduce and / or eliminate odor, there is no need to hide its odor. This in turn leads to another advantage with the use of pentane-1,5-diol since there is no need to use perfumes that can result in allergic reactions in mammals that come in contact with it and since the pentane- 1, 5-diol does not give rise to allergic reactions by itself. Pentane-1,5-diol is also effective as an antimicrobial agent in destroying or reducing the number of bacteria and fungi. It is more effective than various other diols. In addition, there is great access to pentane-1, 5-diol on the market since pentane-1,5-diol is a waste product in the process of making hexanediol which is a major constituent in the manufacture of plastics. In addition, since pentane-1,5-diol is colorless there is no need to color or change the color of a product for the consumer after the application of pentane-1,5-diol. Another additional advantage of pentane-1,5-diol is the fact that it has been shown to have low toxicity and eco-toxicity and that these have been well established. In addition, pentane-1,5-diol has a solubility that is satisfactory with respect to being soluble in polar fluids such as water, sweat, urine, blood, menstruation, feces, leg ulcer liquids, decubitus position ulcers and perspiration and other bodily fluids. This is because the carbon chain has a length that provides a satisfactory solubility but still provides a good effect against odor. Both the solubility in aqueous solutions such as sweat, urine, blood, menstruation, feces, leg ulcer fluids, decubitus position ulcers and perspiration as well as other body fluids and the antimicrobial effect depend, at least partially, on the chain length of the diol. A short chain length provides the diol with good solubility but also a poorer antimicrobial effect. The opposite is valid for longer chains to some extent. Accordingly, these effects are balanced with each other, in terms of providing effective control against the odor of bodily fluids. Except for being odorless, pentane-1,5-diol has a high antimicrobial effect and a satisfactory solubility. Since pentane-1, 5-diol has the positive characteristics mentioned above with respect to providing an effect against odor, pentane-1,5-diol can be used to alleviate the aforementioned drawbacks or other anti-odor agents such as the drawback that the odor agent itself has a strong odor by providing compositions comprising pentane-1 , 5-diol and other anti-odor agents such as other diols. Therefore, in another embodiment of the present invention there is provided a composition that also comprises at least one other diol having the general structure of (CH 2) n H 202, wherein n represents the number of CH 2. For example, n is from 3 to 10, such as 3, 4, 5, 6, 7, 8, 9 or 10. Accordingly, one or more of the diols can have hydroxyl groups in the diols which are connected to different carbon. Examples of the diols are propane-1,2-diol, propane-1,3-diol, butane-1,2-diol, butane-1,3-diol, butane-1,4-diol, 2-methylpropane- 1, 2-diol, 2-methylpropane-1,3-diol, pentane-1,2-diol, pentane-1,3-diol, pentane-1,4-diol, 2-methylpentane-2,4-diol, pentane-2, 3-diol, pentane-2,4-diol, hexane-1,2-diol, hexane-1,3-diol, hexane-1,4-diol, hexane-1,5-diol, hexane- 1,6-diol, hexane-2,3-diol, hexane-2,4-diol, hexane-2,5-diol, hexane-3,4-diol, heptane-1,2-diol, heptane-1, 3-diol, heptane-1, -diol, heptane-L, 5-diol, heptane-1, 6-diol, heptane-1, 7-diol, heptane-2,3-diol, heptane-2,4-diol , heptane-2, 5-diol, heptane-2,6-diol, heptane-3,4-diol, heptane-3,5-diol, octane-1,2-diol, octane-1,3-diol, octane -1,4-diol, octane-1, 5-diol, octane-1,6-diol, octane-L, 7-diol, octane-1, 8-diol, octane-2,3-diol, octane-2 , 4-diol, octane-2, 5-diol, octane-2, 6-diol, octane-2,7-diol, octane-3,4-diol, octane-3, 5-diol, octane-3, 6 -diol and octane-4,5-diol. There may also be a mixture of different diols such as 2, 3, 4 or 5 diols in combination with pentane-1,5-diol. In a further embodiment there is provided a composition, comprising pentane-1,5-diol and at least one of the diols selected from the group consisting of propane-1,2-diol, propane-1,3-diol , butane-1,3-diol, pentane-1,3-diol, and pentane-1,4-diol. Propane-1, 2-diol, propane-1,3-diol, butane-1,3-diol, pentane-1,3-diol, and pentane-1,4-diol which also has a good effect against odors and they do not present such strong and / or unpleasant odors as, for example, pentane-1,2-diol and do not result in toxic metabolic waste products such as, for example, butane-1,4-diol. In a further embodiment a composition is provided, which composition comprises pentane-1,5-diol and propane-1,2-diol and / or butane-1,3-diol, propane-1,2-diol and butane -1, 3-diol have a higher solubility than pentane-1,5-diol in urine, menstruation, feces, leg ulcer fluids, decubitus ulcers, blood and perspiration and a good effect against odor and at the same time They do not have a very strong smell on their own. Thus, a composition comprising a combination of pentane-1,5-diol with these other diols has an improved solubility compared to a composition comprising only pentane-1,5-diol and less odor and improved antimicrobial activity in comparison with a composition comprising only propane-1,2-diol and / or butane-1,3-diol. The stereochemistry of the diols is not important for the present invention and enantiomers, diastereoisomers, tautomers and racemic mixtures can be used with good results. In fact, the requirement that the diols be "different" must be understood to mean that they differ in the connectivity of the atoms (regioisomérismo) and not in if they are, for example R / S or +/-. The pentane-1,5-diol or pentane-1,5-diol and other diols may be present in an amount from about 0.1 to about 99% (v / v) depending on the article in which one or more of the diols are used. . Examples of amounts are 1, 10, 20, 30, 40, 50, 60, 70, 80, 90 or 99%. In consecuense, pentane-1, 5-diol or pentane-1,5-diol and other diols can be used together with other components such as antibacterial, antifungal or antiviral components such as antibiotics, antifungals and antiviral agents. Examples are penicillins, cephalosporins, carbacephems, cefamycins, carbapenems, monobactams, aminoglycosides, glycopeptides, quinolones, tetracyclines, macrolides, fluoroquinolones, imidazoles, allylamines, acyclovir and vectavir. Examples are antiseptic agents and include iodine, silver, copper, chlorhexidine, polyhexanide, alginate, zinc or zinc oxide and other biguanides, acetic acid and hydrogen peroxide. Pentane-1,5-diol or pentane-1,5-diol and other diols can also be agitated together with other compounds such as natural, synthetic or semi-synthetic or identical natural compounds which provide flavor to the product in which is used the diol. The examples are different perfumes, citrus, apple and rose. Absorbent and / or sanitary product The invention also relates to an absorbent and / or sanitary product as defined above in which the product comprises a composition comprising pentane-1,5-diol. In another embodiment, the invention also relates to an absorbent and / or sanitary product as defined above in which the product comprises a composition comprising pentane-1,5-diol and at least one other diol. This diol can comprise between 3 and 8 carbon atoms in a straight or branched chain. Accordingly, one or more of the diols may have hydroxy groups of the diols which are connected to different carbon atoms. Examples of diols are propane-1,2-diol, propane-1,3-diol, butane-1,2-diol, butane-1,3-diol, butane-1, -diol, 2-methylpropane-1, 2-diol, 2-methylpropane-1, 3-diol, pentane-1,2-diol, pentane-1,3-diol, pentane-1,4-diol, 2-methylpentane-2,4-diol, pentane- 2,3-diol, pentane-2,4-diol, hexane-1,2-diol, hexane-1,3-d-ol, hexane-1, -diol, hexane-1,5-d-ol, hexane -1, 6-diol, hexane-2,3-diol, hexane-2,4-diol, hexane-2,5-diol, hexane-3,4-diol, heptane-1,2-diol, heptane-1 , 3-diol, heptane-1, -diol, heptane-1,5-diol, heptane-1, 6-diol, heptane-1, 7-diol, heptane-2,3-diol, heptane-2, 4- diol, heptane-2, 5-diol, heptane-2,6-diol, heptane-3,4-diol, heptane-3,5-diol, octane-1,2-diol, octane-1,3-diol, octane-1,4-diol, octane-1,5-diol, octane-1,6-diol, octane-1,7-diol, octane-1,8-diol, octane-2,3-diol, octane- 2,4-diol, octane-2, 5-diol, octane-2,6-diol, octane-2,7-diol, octane-3,4-diol, octane-3, 5-diol, octane-3, 6-diol and octane-4,5-diol. There may also be a mixture of different diols such as 2, 3, 4 or 5 diols in combination with pentane-1,5-diol. The stereochemistry of the diols is not important for the present invention and the enantiomers, diastereoisomers, tautomers and racemic mixtures of the diols can all be used with good results. In fact, the requirement that the diols be "different" must be understood to mean that they differ in the connectivity of the atoms (regioisomérismo) and not in if they are, for example R / S or +/-. The pentane-1,5-diol or the pentane-1,5-diol and other diols can be present in an amount from about 0.1 to about 99% (v / v) depending on the article in which one or more of the diols. Examples of amounts are 1, 10, 20, 30, 40, 50, 60, 70, 80, 90 or 99%. Accordingly, pentane-1,5-diol or pentane-1,5-diol and other diols can be used together with other components such as antibacterial, antifungal or antiviral components such as an antibiotic, antifungal and antiviral agent. Examples are penicillins, cephalosporins, carbacephems, cefamycins, carbapenems, monobactams, aminoglycosides, glycopeptides, quinolones, tetracyclines, macrolides, fluoroquinolones, imidazoles, allylamines, acyclovir and vectavir. Examples are antiseptic agents that include iodine, silver, copper, chlorhexidine, polyhexanide, alginate, zinc or zinc oxide and other biguanides, acetic acid and hydrogen peroxide. The pentane-1,5-diol or the pentane-1,5-diol and other diols can also be accelerated together with other compounds such as the natural, synthetic or semi-synthetic or identical natural ones which provide flavor to the product in the which is the diol used. The examples are different perfumes, citrus, apple and rose.

The sanitary and / or absorbent article can be any absorbent or sanitary product insofar as the product, when used, provides the new properties of reduction and / or odor elimination of mammalian liquids such as human or animal liquids. Examples are a disposable absorbent sheet, an air freshening product, a diaper, a pad for underwear, tampons, bandages, compresses, face mask, air filtering device, sanitary napkin, tampon, panty protection, incontinence pad , incontinence device, surgical dressing, adhesive bandage, a paper product containing one or more paper membranes such as a face towel, a bath towel, paper towels and sanitary napkins. The invention also relates to a package comprising one or more absorbent and / or sanitary articles as defined above. The invention also relates to a method of manufacturing an absorbent and / or sanitary article as defined above. The following examples are designed to illustrate but do not limit the invention in any way in terms of shape or form, either explicitly or implicitly. EXAMPLES Example 1 Active solutions containing pentane-1,5-diol 10% (v / v) and 30% (v / v) are sprayed on a disposable sanitary napkin, until it is moistened to the entire area of the sanitary napkin. The sanitary towel is left at room temperature until the sanitary towel is dried. The sanitary towel is then used to remove urine from a human being. After the urine is removed by the sanitary napkin, it is found that there is no smell of urine evolved from the sanitary napkin, which is pleasant for the consumer of the sanitary napkin. As a control, water alone was used. The same amount of water and the active solution were used. EXAMPLE 2 The same solution as in Example 1 was sprayed on a women's diaper until the entire diaper was covered by the solution. The diaper was left at room temperature to dry. When the diaper was used by a woman with urinary leakage problems, no aroma could be detected even after a longer period of use. Example 3 Compresses were sprayed in the same manner and with the same solutions as in example 1. Example 4 Compresses were sprayed in the same manner and with the same solutions as in example 1. The compresses can be used as a compress and They can be applied on an ulcer such as an ulcer on one leg or an ulcer by decubitus position. Although the present invention has been described in the foregoing with reference to specific embodiments, it is not intended to be limited to the specific form set forth herein. Instead, the invention is limited only by the appended claims and other embodiments in addition to those specific to the foregoing are equally possible within the scope of these appended claims. In the claims, the term "comprising / included" does not exclude the presence of other elements or steps. In addition, although they are included individually, a plurality of means, elements or steps of methods can be implemented by for example a single unit or processor. Additionally, although different individual features may be included in claims, these may possibly be advantageously combined and inclusion in different claims does not imply that the feature combination is not feasible and / or advantageous. In addition, the singular reference does not exclude the plural. The terms "a", "one", "first", "second", etc. do not prevent plurality. The reference numbers in the claims are provided only as a clarifying example and should not be considered as limiting the scope of the claims in any way.

It is noted that in relation to this date, the best method known to the applicant to carry out the aforementioned invention is that which is clear from the present description of the invention.

Claims (13)

1. - CLAIMS Having described the invention as above, the content of the following claims is claimed as property: 1. An absorption product, characterized in that it comprises pentane-1,5-diol to reduce and / or eliminate the odor of a mammal, such as the smell of urine, menstruation, stools, liquid ulcers on the legs, ulcers from lying down, blood and perspiration.
2. 2. The absorption product according to claim 1, characterized in that it comprises at least one other diol, at least one diol having the general structure of (CH2) nH202, wherein n represents the number of CH2.
3. 3. The absorption product according to claim 2, characterized in that it is selected from 3 to 10 such as 3, 4, 5, 6, 7, 8, 9, or 10.
4. 4. The absorption product according to claim 2 or 3, characterized in that the hydroxy groups of the diols are connected to different carbon atoms in the diol.
5. 5. The absorption product according to claim 2 or 3, characterized in that the diol is selected from the group consisting of propane-1,2-diol, propane-1,3-diol, butane-1,2-diol , butane-1, 3-diol, butane-1,4-diol, 2-methylpropane-1, 2-diol, 2-methylpropane-1, 3-diol, pentane-1,2-diol, pentane-1, 3 -diol, pentane-1, -diol, pentane-2,3-diol, pentane-2,4-diol, 2-methylpentane-2, -diol, hexane-1,2-diol, hexane-1,3-diol , hexane-1,4-diol, hexane-1,5-diol, hexane-1,6-diol, hexane-2,3-diol, hexane-2, -diol, hexane-2,5-diol, hexane- 3,4-diol, heptane-1,2-diol, heptane-1,3-diol, heptane-1,4-diol, heptane-1,5-diol, heptane-1,6-diol, heptane-1, 7-diol, heptane-2,3-diol, heptane-2,4-diol, heptane-2,5-diol, heptane-2,6-diol, heptane-3,4-diol, heptane-3, 5- diol, octane-1,2-diol, octane-1,3-diol, octane-1, -diol, octane-1,5-diol, octane-1,6-diol, octane-1,7-diol, octane -1,8-diol, octane-2, 3-diol, octane-2,4-diol, octane-2,5-diol, octane-2, 6-diol, octane-2, 7-diol, octane-3,4-diol, octane-3, 5-diol, octane-3,6-diol and octane-4,5-diol.
6. 6. The absorption product according to claim 5, characterized in that the diol is selected from the group consisting of propane-1,2-diol, butane-1,3-diol, pentane-1,3-diol and pentane- 1,4-diol.
7. The absorption product according to claim 1, characterized in that the composition comprises one or more components that are selected from the group consisting of antibacterial and / or antifungal components such as antibiotics and antiviral agents.
8. 8. The absorption product according to claim 7, characterized in that the antibacterial and / or antifungal components are selected from the group consisting of penicillins, cephalosporins, carbacephems, cefamycins, carbapenems, monobactams, aminoglycosides, glycopeptides, quinolones, tetracyclines, macrolides , fluoroquinolones, imidazoles, allylamines, acyclovir and vectavir.
9. 9. The absorption product according to claim 1, characterized in that it comprises an antiseptic agent.
10. 10. The absorption product according to claim 9, characterized in that the antiseptic agent is selected from the group consisting of iodine, silver, copper, chlorhexidine, polyhexanide, alginate, zinc or zinc oxide and other biguanides, acetic acid and peroxide of hydrogen.
11. 11. The absorption product according to claim 1, characterized in that it comprises synthetic or semi-synthetic substances that provide identical natural flavors.
12. 12. The absorption product according to claim 1, characterized in that it is selected from the group consisting of a disposable absorbent sheet, an air freshening product, diaper, a pad for underwear, tampons, bandages, compresses, face mask, air filtration device, sanitary napkin, tampon, cover for panties, incontinence pad, incontinence device, surgical dressing, adhesive bandage, a paper product that contains one or more paper membranes such as a facial tissue, a toilet paper for bath, paper towels and sanitary napkins.
13. 13. A method for manufacturing an absorption product, characterized in that it comprises the steps of: a) providing an absorption product, b) applying a composition comprising pentane-1,5-diol in the absorption product and by means of the which obtains an absorption product that reduces and / or eliminates the odor of a mammal, such as the smell such as that which is produced from urine, feces, leg ulcer liquids, pressure ulcers, blood and transpiration.