ME02477B - Genz 112638 za lečenje gošeove ili fabrijeve bolesti u kombinacionoj terapiji - Google Patents

Genz 112638 za lečenje gošeove ili fabrijeve bolesti u kombinacionoj terapiji

Info

Publication number: ME02477B
Authority: ME; Montenegro
Prior art keywords: genz; combination therapy; fabry disease; treating gaucher; gaucher
Prior art date: 2009-11-27

Application number

MEP-2016-163A

Other languages

German (de)

English (en)

French (fr)

Inventor

Hanlan Liu

Chris Willis

Renu Bhardwaj

Diane P Copeland

Abizer Harianawala

Jeffrey Skell

John Marshall

Jianmei Kochling

Gerard Palace

Judith Peterschmitt

Craig Siegel

Seng Cheng

Original Assignee

Genzyme Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-11-27

Filing date

2010-11-24

Publication date

2017-02-20

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43431870&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME02477(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2010-11-24 Application filed by Genzyme Corp filed Critical Genzyme Corp

2017-02-20 Publication of ME02477B publication Critical patent/ME02477B/me

Links

208000024720 Fabry Disease Diseases 0.000 title 1
208000015872 Gaucher disease Diseases 0.000 title 1
238000002648 combination therapy Methods 0.000 title 1
229960002856 eliglustat Drugs 0.000 title 1
KUBARPMUNHKBIQ-VTHUDJRQSA-N eliglustat tartrate Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.C([C@@H](NC(=O)CCCCCCC)[C@H](O)C=1C=C2OCCOC2=CC=1)N1CCCC1.C([C@@H](NC(=O)CCCCCCC)[C@H](O)C=1C=C2OCCOC2=CC=1)N1CCCC1 KUBARPMUNHKBIQ-VTHUDJRQSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Steroid Compounds (AREA)

MEP-2016-163A 2009-11-27 2010-11-24 Genz 112638 za lečenje gošeove ili fabrijeve bolesti u kombinacionoj terapiji ME02477B (me)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US26474809P	2009-11-27	2009-11-27
EP14164650.5A EP2796457B1 (en)	2009-11-27	2010-11-24	Genz 112638 for treating Gaucher or Fabry disease in combination therapy

Publications (1)

Publication Number	Publication Date
ME02477B true ME02477B (me)	2017-02-20

Family

ID=43431870

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MEP-2016-163A ME02477B (me)	2009-11-27	2010-11-24	Genz 112638 za lečenje gošeove ili fabrijeve bolesti u kombinacionoj terapiji

Country Status (41)

Country	Link
US (6)	US11458119B2 (me)
EP (5)	EP2796457B1 (me)
JP (6)	JP2013512252A (me)
KR (5)	KR20220162824A (me)
CN (5)	CN105777707B (me)
AR (3)	AR079152A1 (me)
AU (3)	AU2010324810B2 (me)
BR (1)	BR112012012947B8 (me)
CA (3)	CA3075788C (me)
CL (2)	CL2012001348A1 (me)
CR (1)	CR20120277A (me)
CY (3)	CY1115880T1 (me)
DK (3)	DK3133070T3 (me)
DO (2)	DOP2012000141A (me)
EA (3)	EA029990B1 (me)
EC (2)	ECSP12011926A (me)
ES (4)	ES2493940T5 (me)
GT (1)	GT201200161A (me)
HK (2)	HK1203485A1 (me)
HR (3)	HRP20140780T4 (me)
HU (2)	HUE045784T2 (me)
IL (4)	IL310635A (me)
LT (2)	LT3133070T (me)
MA (1)	MA33838B1 (me)
ME (1)	ME02477B (me)
MX (1)	MX358345B (me)
MY (2)	MY192644A (me)
NI (1)	NI201200096A (me)
NZ (3)	NZ600155A (me)
PE (2)	PE20121337A1 (me)
PH (1)	PH12015502514A1 (me)
PL (4)	PL2796457T3 (me)
PT (4)	PT2504332E (me)
RS (3)	RS53503B2 (me)
SG (2)	SG10201800136QA (me)
SI (3)	SI3133070T1 (me)
SM (1)	SMT201600273B (me)
TN (1)	TN2012000237A1 (me)
TW (3)	TWI586663B (me)
UA (1)	UA113491C2 (me)
WO (1)	WO2011066352A1 (me)

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CA3075788A1 (en)	2011-06-03
HK1203485A1 (zh)	2015-10-30
BR112012012947A2 (pt)	2017-03-01
AU2016202591A1 (en)	2016-05-19
CR20120277A (es)	2012-09-05
ES2493940T5 (es)	2021-11-23
UA113491C2 (xx)	2017-02-10
US20160120842A1 (en)	2016-05-05
BR112012012947B1 (pt)	2021-04-06
SG10201407881WA (en)	2015-01-29
WO2011066352A8 (en)	2011-08-11
AU2017265180B2 (en)	2019-08-01
EA201890254A3 (ru)	2019-02-28
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IL260299A (en)	2018-08-30
CY1122698T1 (el)	2021-03-12
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LT3133070T (lt)	2019-11-11
CL2012001348A1 (es)	2012-08-24
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JP6452635B2 (ja)	2019-01-16
SI2796457T1 (sl)	2016-10-28
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KR20120115972A (ko)	2012-10-19
PL2796457T3 (pl)	2017-04-28
CN112521367B (zh)	2024-01-02

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