MD4506C1 - Polymeric material with antibacterial properties based on lignin grafted with N'-(5-nitrofurfurylidene)isonicotinehydrazide - Google Patents

Polymeric material with antibacterial properties based on lignin grafted with N'-(5-nitrofurfurylidene)isonicotinehydrazide

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Publication number
MD4506C1
MD4506C1 MDA20160128A MD20160128A MD4506C1 MD 4506 C1 MD4506 C1 MD 4506C1 MD A20160128 A MDA20160128 A MD A20160128A MD 20160128 A MD20160128 A MD 20160128A MD 4506 C1 MD4506 C1 MD 4506C1
Authority
MD
Moldova
Prior art keywords
polymeric material
lignin
isonicotinehydrazide
nitrofurfurylidene
antibacterial
Prior art date
Application number
MDA20160128A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD4506B1 (en
Inventor
Штефан РОБУ
Виорел ПРИСАКАРЬ
Вячеслав КУЛЧИТСКИЙ
Марина ГРИНКО
Алик БАРБА
Original Assignee
Государственный Университет Молд0
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Государственный Университет Молд0 filed Critical Государственный Университет Молд0
Priority to MDA20160128A priority Critical patent/MD4506C1/en
Publication of MD4506B1 publication Critical patent/MD4506B1/en
Publication of MD4506C1 publication Critical patent/MD4506C1/en

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  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

The invention relates to the field of medicine and chemistry, namely to new polymeric antibacterial materials based on lignin.Summary of the invention consists in that a polymeric material with antibacterial properties is proposed, which is a lignin grafted with the antibacterial preparation N'-(5-nitrofurfurylidene)isonicotinehydrazide (isofural), wherein the isofural content is of 30…50 wt.%. At the same time, the grafting is performed by preliminary activation of lignin with ethyl chloroformate in the presence of an organic base in dimethylformamide at 0°C.The polymeric material has an antibacterial effect at micromolecular isofural level, low toxicity and is soluble in the dimethylformamide-water mixture (1:1).
MDA20160128A 2016-11-24 2016-11-24 Polymeric material with antibacterial properties based on lignin grafted with N'-(5-nitrofurfurylidene)isonicotinehydrazide MD4506C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20160128A MD4506C1 (en) 2016-11-24 2016-11-24 Polymeric material with antibacterial properties based on lignin grafted with N'-(5-nitrofurfurylidene)isonicotinehydrazide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20160128A MD4506C1 (en) 2016-11-24 2016-11-24 Polymeric material with antibacterial properties based on lignin grafted with N'-(5-nitrofurfurylidene)isonicotinehydrazide

Publications (2)

Publication Number Publication Date
MD4506B1 MD4506B1 (en) 2017-08-31
MD4506C1 true MD4506C1 (en) 2018-03-31

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20160128A MD4506C1 (en) 2016-11-24 2016-11-24 Polymeric material with antibacterial properties based on lignin grafted with N'-(5-nitrofurfurylidene)isonicotinehydrazide

Country Status (1)

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MD (1) MD4506C1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111558328B (en) * 2020-05-25 2023-09-01 雅思汀娜(北京)科技有限公司 Lignin cationic surfactant and preparation method thereof, and long-acting antibacterial agent and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD196C2 (en) * 1994-07-22 1995-10-31 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Izonicotinoilhydrazone of 5-nitro-2 furanaldehyde
RU2185166C2 (en) * 2000-04-03 2002-07-20 Новосибирская государственная медицинская академия Agent for treatment of tuberculosis with low level of fibrotic complications
MD4399B1 (en) * 2015-02-19 2016-02-29 Universitatea De Stat Din Moldova Polymeric material with antibacterial properties

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD196C2 (en) * 1994-07-22 1995-10-31 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Izonicotinoilhydrazone of 5-nitro-2 furanaldehyde
RU2185166C2 (en) * 2000-04-03 2002-07-20 Новосибирская государственная медицинская академия Agent for treatment of tuberculosis with low level of fibrotic complications
MD4399B1 (en) * 2015-02-19 2016-02-29 Universitatea De Stat Din Moldova Polymeric material with antibacterial properties

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
G. Gellenstedt and G. Henrikson. Lignins: Major Sources, Structure and Properties, in Monomers, Polymers and Composites from Renewable Resources, ed. by M. N. Belgacem and Al. Gandini. Elsevier, 2008, pag. 201-224 *
S. Laurichesse, L Averous. Chemical modification of lignins: Towards biobased polymers. Progres in Polymer Science, 39, Issue 7, July 2014 regăsit în Internet la 2017.06.23, url: https://www.researchgate.net/profile/Luc_Averous2/publication/259095789_Chemical_modification_of_lignins_Towards_biobased_polymers/links/54f70d120cf210398e90eaaf/Chemical-modification-of-lignins-Towards-biobased-polymers.pdf Chapter 4.4. Functionalization of hydroxyl groups *
V. Prisacari, S. Buraciov, A. Dizdari, S. Stoletov, V. Ţapcov. "Izofuralul - remediu nou antibacterian". Analele Ştiinţifice ale USMF "N. Testemiţanu", Chişinău, 2003, p.240-243 *

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FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees