MD3273G2 - Process for obtaining drimenol acetate from 11-monoacetate drimane-8-a,11-diol - Google Patents
Process for obtaining drimenol acetate from 11-monoacetate drimane-8-a,11-diolInfo
- Publication number
- MD3273G2 MD3273G2 MDA20060187A MD20060187A MD3273G2 MD 3273 G2 MD3273 G2 MD 3273G2 MD A20060187 A MDA20060187 A MD A20060187A MD 20060187 A MD20060187 A MD 20060187A MD 3273 G2 MD3273 G2 MD 3273G2
- Authority
- MD
- Moldova
- Prior art keywords
- drimenol
- drimane
- monoacetate
- acetate
- diol
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention relates to the sesquiterpenoide chemistry, in particular to a process for obtaining drimenol acetate, a valuable intermediate compound used in the synthesis of biologically active compounds, from 11-monoacetate drimane-8α,11-diol.The process for obtaining drimenol acetate from 11-monoacetate, drimane-8α,11-diol includes dissolution of 11-monoacetate drimane-8α,11-diol in acetonitrile, treatment of the obtained solution with trimethylsilylic ester of the methane-sulphonic acid taken in the molar excess of 1:5, agitation of the reaction mixture during 10 minutes at a temperature of 0…20°C, dilution and extraction of the mixture, washing, drying, filtration of the extract and solvent removal in vacuum. At the same time the drimenol acetate is isolated by column silica gel chromatography.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MDA20060187A MD3273G2 (en) | 2006-07-14 | 2006-07-14 | Process for obtaining drimenol acetate from 11-monoacetate drimane-8-a,11-diol |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MDA20060187A MD3273G2 (en) | 2006-07-14 | 2006-07-14 | Process for obtaining drimenol acetate from 11-monoacetate drimane-8-a,11-diol |
Publications (2)
Publication Number | Publication Date |
---|---|
MD3273F1 MD3273F1 (en) | 2007-03-31 |
MD3273G2 true MD3273G2 (en) | 2007-10-31 |
Family
ID=37909220
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDA20060187A MD3273G2 (en) | 2006-07-14 | 2006-07-14 | Process for obtaining drimenol acetate from 11-monoacetate drimane-8-a,11-diol |
Country Status (1)
Country | Link |
---|---|
MD (1) | MD3273G2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MD4248C1 (en) * | 2013-04-19 | 2014-03-31 | Институт Химии Академии Наук Молдовы | Process for producing 14,15-bisnorlabdane-8(9)-en-13-one |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3140410B1 (en) * | 2014-05-06 | 2019-09-11 | Firmenich SA | Drimenol synthases and method of producing drimenol |
-
2006
- 2006-07-14 MD MDA20060187A patent/MD3273G2/en not_active IP Right Cessation
Non-Patent Citations (3)
Title |
---|
A. Barrero, E.A. Manzaneda, J. Altarejos, S. Salido, J.M. Ramos, M.S.J. Simmonds, W.M. Blaney. Tetrahedron, 1995, V51, N27, p. 7435-7450 * |
Влaд, A.H. Apыку, A.Г. Чoкырлaн. Известия РАН, Сер. хuм, 2004, №2, с. 423-426 * |
П.Ф. Влaд, A.H. Apыку, A.Г. Чoкырлaн. Известия РАН, Сер. xuм., 2004, №2, с. 423-426 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MD4248C1 (en) * | 2013-04-19 | 2014-03-31 | Институт Химии Академии Наук Молдовы | Process for producing 14,15-bisnorlabdane-8(9)-en-13-one |
Also Published As
Publication number | Publication date |
---|---|
MD3273F1 (en) | 2007-03-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Usuki et al. | Extraction and isolation of shikimic acid from Ginkgo biloba leaves utilizing an ionic liquid that dissolves cellulose | |
CN103923055B (en) | The method of (1S, 2R, 3S, 4R) is prepared by one-2,3-O-isopropylidene-4-Aminocyclopentane-1,2,3-triols | |
CN103333942A (en) | A synthetic method for (R)-praziquantel | |
EP3045459B1 (en) | Method for preparing intermediate compound of sitagliptin | |
Song et al. | Enantiopure azetidine-2-carboxamides as organocatalysts for direct asymmetric aldol reactions in aqueous and organic media | |
CN102911160B (en) | Method for preparing and purifying dabigatran etexilate intermediate | |
CN103641761A (en) | Vildagliptin preparation method | |
Turks et al. | Novel 3-C-aminomethyl-hexofuranose-derived thioureas and their testing in asymmetric catalysis | |
CN103788069A (en) | Preparation method for esomeprazole magnesium trihydrate | |
MD3273G2 (en) | Process for obtaining drimenol acetate from 11-monoacetate drimane-8-a,11-diol | |
CN105148988A (en) | Chiral pyridoxal catalysts and synthetic method therefor and application thereof | |
CN103304467A (en) | Method for preparing N-coffee acyl tryptamine by one-step process | |
CN104530112B (en) | The preparation method of everolimus intermediate and its ethylization impurity | |
UA95781C2 (en) | Process of preparing bromopicrin | |
CN108276299A (en) | Synthetic method of the Dapoxetine hydrochloride in relation to substance | |
WO2015189862A1 (en) | Chiral amines, a process for preparation and use thereof | |
CN104016954A (en) | Method for preparing and purifying nebivolol intermediate | |
WO2007070238A3 (en) | Processes for the preparation of modafinil and analogs thereof | |
CN110894198B (en) | Xanthine compound and preparation method and application thereof | |
Tang et al. | Chirality conversion and enantioselective extraction of amino acids by imidazolium-based binol-aldehyde | |
CN101654426B (en) | Method for preparing ilomastat | |
Bentama et al. | Synthesis of new α-heterocyclic α-aminoesters | |
KR20090101462A (en) | Pregabalin-4-eliminate, pregabalin-5-eliminate, their use as reference marker and standard, and method to produce pregabalin containing low levels thereof | |
CN104672243A (en) | Method for preparing vildagliptin degraded impurities | |
CN103539796A (en) | Preparation method of levo praziquantel as well as intermediate thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG4A | Patent for invention issued | ||
KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
MM4A | Patent for invention definitely lapsed due to non-payment of fees |