MD3273G2 - Process for obtaining drimenol acetate from 11-monoacetate drimane-8-a,11-diol - Google Patents

Process for obtaining drimenol acetate from 11-monoacetate drimane-8-a,11-diol

Info

Publication number
MD3273G2
MD3273G2 MDA20060187A MD20060187A MD3273G2 MD 3273 G2 MD3273 G2 MD 3273G2 MD A20060187 A MDA20060187 A MD A20060187A MD 20060187 A MD20060187 A MD 20060187A MD 3273 G2 MD3273 G2 MD 3273G2
Authority
MD
Moldova
Prior art keywords
drimenol
drimane
monoacetate
acetate
diol
Prior art date
Application number
MDA20060187A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD3273F1 (en
Inventor
Павел ВЛАД
Калерия КУЧЬКОВА
Акулина АРЫКУ
Алик БАРБА
Original Assignee
Институт Химии Академии Наук Молдовы
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Институт Химии Академии Наук Молдовы filed Critical Институт Химии Академии Наук Молдовы
Priority to MDA20060187A priority Critical patent/MD3273G2/en
Publication of MD3273F1 publication Critical patent/MD3273F1/en
Publication of MD3273G2 publication Critical patent/MD3273G2/en

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to the sesquiterpenoide chemistry, in particular to a process for obtaining drimenol acetate, a valuable intermediate compound used in the synthesis of biologically active compounds, from 11-monoacetate drimane-8α,11-diol.The process for obtaining drimenol acetate from 11-monoacetate, drimane-8α,11-diol includes dissolution of 11-monoacetate drimane-8α,11-diol in acetonitrile, treatment of the obtained solution with trimethylsilylic ester of the methane-sulphonic acid taken in the molar excess of 1:5, agitation of the reaction mixture during 10 minutes at a temperature of 0…20°C, dilution and extraction of the mixture, washing, drying, filtration of the extract and solvent removal in vacuum. At the same time the drimenol acetate is isolated by column silica gel chromatography.
MDA20060187A 2006-07-14 2006-07-14 Process for obtaining drimenol acetate from 11-monoacetate drimane-8-a,11-diol MD3273G2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20060187A MD3273G2 (en) 2006-07-14 2006-07-14 Process for obtaining drimenol acetate from 11-monoacetate drimane-8-a,11-diol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20060187A MD3273G2 (en) 2006-07-14 2006-07-14 Process for obtaining drimenol acetate from 11-monoacetate drimane-8-a,11-diol

Publications (2)

Publication Number Publication Date
MD3273F1 MD3273F1 (en) 2007-03-31
MD3273G2 true MD3273G2 (en) 2007-10-31

Family

ID=37909220

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20060187A MD3273G2 (en) 2006-07-14 2006-07-14 Process for obtaining drimenol acetate from 11-monoacetate drimane-8-a,11-diol

Country Status (1)

Country Link
MD (1) MD3273G2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4248C1 (en) * 2013-04-19 2014-03-31 Институт Химии Академии Наук Молдовы Process for producing 14,15-bisnorlabdane-8(9)-en-13-one

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3140410B1 (en) * 2014-05-06 2019-09-11 Firmenich SA Drimenol synthases and method of producing drimenol

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
A. Barrero, E.A. Manzaneda, J. Altarejos, S. Salido, J.M. Ramos, M.S.J. Simmonds, W.M. Blaney. Tetrahedron, 1995, V51, N27, p. 7435-7450 *
Влaд, A.H. Apыку, A.Г. Чoкырлaн. Известия РАН, Сер. хuм, 2004, №2, с. 423-426 *
П.Ф. Влaд, A.H. Apыку, A.Г. Чoкырлaн. Известия РАН, Сер. xuм., 2004, №2, с. 423-426 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4248C1 (en) * 2013-04-19 2014-03-31 Институт Химии Академии Наук Молдовы Process for producing 14,15-bisnorlabdane-8(9)-en-13-one

Also Published As

Publication number Publication date
MD3273F1 (en) 2007-03-31

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees