MD2633B2 - Procedeu de aplicare a invelisului antibiotic pe corpuri cu microcavitati interconexe (variante), corp cu microcavitati interconexe cu invelis antibiotic (variante) si utilizarea acestuia - Google Patents
Procedeu de aplicare a invelisului antibiotic pe corpuri cu microcavitati interconexe (variante), corp cu microcavitati interconexe cu invelis antibiotic (variante) si utilizarea acestuiaInfo
- Publication number
- MD2633B2 MD2633B2 MDA20020153A MD20020153A MD2633B2 MD 2633 B2 MD2633 B2 MD 2633B2 MD A20020153 A MDA20020153 A MD A20020153A MD 20020153 A MD20020153 A MD 20020153A MD 2633 B2 MD2633 B2 MD 2633B2
- Authority
- MD
- Moldova
- Prior art keywords
- gentamicin
- microcavities
- variants
- antibiotic coating
- bodies
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
- A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/249921—Web or sheet containing structurally defined element or component
- Y10T428/249953—Composite having voids in a component [e.g., porous, cellular, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Dispersion Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Fertilizers (AREA)
- Laminated Bodies (AREA)
- Saccharide Compounds (AREA)
Abstract
Inventia se refera la medicina si la medicina veterinara, in particular la un procedeu de aplicare a unui invelis antibiotic pe corpurile cu microcavitati interconexe, la corp cu invelis aplicat prin acest procedeu si la utilizarea acestuia.Procedeul de aplicare a unui invelis antibiotic pe corpurile cu microcavitati interconexe include introducerea in microcavitati prin impregnare, pulverizare sau picurare a unei solutii de pentakisdodecilsulfat de gentamicina; de tetrakisdodecilsulfat de gentamicina; de pentakisdodecilsulfonat de gentamicina sau tetrakisdodecilsulfonat de gentamicina. In calitate de solvent se utilizeaza metanol si/sau etanol, si/sau N,N-dimetilformamida, si/sau dimetilsulfoxid, dupa care solventul organic se elimina, iar pe suprafata microcavitatilor se formeaza un strat de pentakisdodecilsulfat de gentamicina, tetrakisdodecilsulfat de gentamicina, pentakisdodecilsulfonat de gentamicina, tetrakisdodecilsulfonat de gentamicina.Corpurile cu invelis antibiotic, realizate din colagen sau gelatina, sau poliesteri, sau fosfat tricalcic, sau hidroxilapatit, sau titan, sau aliaje de titan, sau otel de inalta calitate, se utilizeaza ca implant. ŕ
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10142465A DE10142465A1 (de) | 2001-08-31 | 2001-08-31 | Verfahren zur antibiotischen Beschichtung von nichtmetallischen Körpern mit interkonnektierenden Mikrohohlräumen, nichtmetallischer Körper sowie seine Verwendung |
DE10204307 | 2002-02-01 |
Publications (3)
Publication Number | Publication Date |
---|---|
MD20020153A MD20020153A (ro) | 2003-03-31 |
MD2633B2 true MD2633B2 (ro) | 2004-12-31 |
MD2633C2 MD2633C2 (ro) | 2005-08-31 |
Family
ID=26010028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDA20020153A MD2633C2 (ro) | 2001-08-31 | 2002-06-03 | Procedeu de aplicare a învelişului antibiotic pe corpuri cu microcavităţi interconexe (variante), corp cu microcavităţi interconexe cu inveliş antibiotic (variante) şi utilizarea acestuia |
Country Status (29)
Country | Link |
---|---|
US (1) | US6984410B2 (ro) |
EP (1) | EP1287818B1 (ro) |
JP (1) | JP3740449B2 (ro) |
CN (1) | CN1203903C (ro) |
AU (1) | AU2002300656B2 (ro) |
BG (1) | BG65774B1 (ro) |
BR (1) | BR0203427A (ro) |
CA (1) | CA2396146C (ro) |
CY (1) | CY1107271T1 (ro) |
CZ (1) | CZ301740B6 (ro) |
DE (1) | DE50211246D1 (ro) |
DK (1) | DK1287818T3 (ro) |
EE (1) | EE200200491A (ro) |
ES (1) | ES2295268T3 (ro) |
GE (1) | GEP20043333B (ro) |
HR (1) | HRP20020680B1 (ro) |
HU (1) | HUP0202916A3 (ro) |
IL (1) | IL150999A0 (ro) |
IS (1) | IS6390A (ro) |
MD (1) | MD2633C2 (ro) |
MX (1) | MXPA02008326A (ro) |
NO (1) | NO20024101L (ro) |
NZ (1) | NZ521043A (ro) |
PL (1) | PL206972B1 (ro) |
PT (1) | PT1287818E (ro) |
RU (1) | RU2236261C2 (ro) |
SA (1) | SA02230286B1 (ro) |
SK (1) | SK9852002A3 (ro) |
YU (1) | YU51902A (ro) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10262176B4 (de) * | 2002-06-21 | 2007-10-04 | Heraeus Kulzer Gmbh | Verfahren zur Herstellung von antibiotisch beschichteten porösen Körpern sowie Verwendung |
ITFI20030105A1 (it) * | 2003-04-14 | 2004-10-15 | Italmed Di Galli Giovanna E Pacini Gigliola S N C | Composizione ad uso odontoiatrico per la rigenerazione ossea |
US20070134287A1 (en) * | 2005-12-09 | 2007-06-14 | Biomet Manufacturing Corp | Method for coating biocompatible substrates with antibiotics |
DE102006016598A1 (de) * | 2006-04-06 | 2007-11-15 | Heraeus Kulzer Gmbh | Beschichtete Vaskulärimplantate |
JP5161452B2 (ja) | 2006-10-03 | 2013-03-13 | 日本コヴィディエン株式会社 | 医療用具の製造方法、医療用具の表面に抗生物質を付与する方法および医療用具 |
CN101721750B (zh) * | 2009-12-25 | 2013-08-07 | 安徽医科大学 | 一种抗菌可降解活性纳米复合仿生骨组织修复材料的制备方法 |
DE102010055560B4 (de) | 2010-12-23 | 2017-02-23 | Heraeus Medical Gmbh | Beschichtungsvorrichtung |
DE102012002209A1 (de) * | 2012-02-07 | 2013-08-08 | Carl Freudenberg Kg | Biodegradierbares Vlies für medizinische Zwecke |
US10662292B2 (en) | 2016-09-27 | 2020-05-26 | Wacker Chemie Ag | Process for producing spherical polysilsesquioxane particles |
US10662293B2 (en) | 2016-10-06 | 2020-05-26 | Wacker Chemie Ag | Method for producing spherical polysilsesquioxane particles |
WO2019084117A1 (en) | 2017-10-24 | 2019-05-02 | University Of Cincinnati | IMPLANT COATINGS AND METHOD FOR MANUFACTURING IMPLANT COATINGS |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA950831A (en) * | 1972-04-25 | 1974-07-09 | Leonard D. Kurtz | Biocidal salts |
FR2272680B1 (ro) * | 1974-05-29 | 1978-07-21 | Hosbon Sa Lab | |
DE2807132C2 (de) * | 1978-02-20 | 1983-11-03 | Battelle-Institut E.V., 6000 Frankfurt | Implantierbares Pharmaka-Depot |
DE3206725A1 (de) | 1981-05-13 | 1982-12-02 | Merck Patent Gmbh, 6100 Darmstadt | Schwer loesliche salze von aminoglykosidantibiotika |
DE3206726A1 (de) | 1982-02-25 | 1983-09-01 | Merck Patent Gmbh, 6100 Darmstadt | Pharmakadepot |
DE4314871A1 (de) * | 1993-05-05 | 1994-11-10 | Merck Patent Gmbh | Lösungsmittel für ein schwerlösliches Gentamicin-Salz |
DE4404018A1 (de) * | 1994-02-09 | 1995-08-10 | Merck Patent Gmbh | Protrahiert freisetzende Darreichungsformen enthaltend Clindamycin-Palmitat |
US5624704A (en) * | 1995-04-24 | 1997-04-29 | Baylor College Of Medicine | Antimicrobial impregnated catheters and other medical implants and method for impregnating catheters and other medical implants with an antimicrobial agent |
WO1997038698A1 (en) | 1996-04-18 | 1997-10-23 | University Technology Corporation | Methods for treating middle and inner ear disorders |
US6417293B1 (en) * | 2000-12-04 | 2002-07-09 | Dow Corning Corporation | Thermoplastic silicone elastomers formed from polyester resins |
DE10114245A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung |
-
2002
- 2002-05-17 IS IS6390A patent/IS6390A/is unknown
- 2002-06-03 MD MDA20020153A patent/MD2633C2/ro not_active IP Right Cessation
- 2002-06-27 BG BG106881A patent/BG65774B1/bg unknown
- 2002-07-02 CZ CZ20022322A patent/CZ301740B6/cs not_active IP Right Cessation
- 2002-07-04 SK SK985-2002A patent/SK9852002A3/sk unknown
- 2002-07-05 YU YUP51902 patent/YU51902A/sh unknown
- 2002-07-29 CA CA 2396146 patent/CA2396146C/en not_active Expired - Fee Related
- 2002-07-31 IL IL15099902A patent/IL150999A0/xx not_active IP Right Cessation
- 2002-08-12 GE GEAP2002004867 patent/GEP20043333B/en unknown
- 2002-08-13 US US10/217,788 patent/US6984410B2/en not_active Expired - Fee Related
- 2002-08-14 EP EP20020018322 patent/EP1287818B1/de not_active Expired - Lifetime
- 2002-08-14 DE DE50211246T patent/DE50211246D1/de not_active Expired - Lifetime
- 2002-08-14 PT PT02018322T patent/PT1287818E/pt unknown
- 2002-08-14 DK DK02018322T patent/DK1287818T3/da active
- 2002-08-14 ES ES02018322T patent/ES2295268T3/es not_active Expired - Lifetime
- 2002-08-19 AU AU2002300656A patent/AU2002300656B2/en not_active Ceased
- 2002-08-20 HR HR20020680A patent/HRP20020680B1/xx not_active IP Right Cessation
- 2002-08-27 NZ NZ521043A patent/NZ521043A/en not_active IP Right Cessation
- 2002-08-27 MX MXPA02008326A patent/MXPA02008326A/es active IP Right Grant
- 2002-08-28 NO NO20024101A patent/NO20024101L/no not_active Application Discontinuation
- 2002-08-28 BR BR0203427A patent/BR0203427A/pt not_active IP Right Cessation
- 2002-08-28 JP JP2002249580A patent/JP3740449B2/ja not_active Expired - Fee Related
- 2002-08-29 PL PL355778A patent/PL206972B1/pl not_active IP Right Cessation
- 2002-08-30 RU RU2002123420A patent/RU2236261C2/ru not_active IP Right Cessation
- 2002-08-30 HU HU0202916A patent/HUP0202916A3/hu unknown
- 2002-08-30 CN CNB02141503XA patent/CN1203903C/zh not_active Expired - Fee Related
- 2002-08-30 EE EEP200200491A patent/EE200200491A/xx unknown
- 2002-09-03 SA SA02230286A patent/SA02230286B1/ar unknown
-
2008
- 2008-01-18 CY CY081100074T patent/CY1107271T1/el unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
MM4A | Patent for invention definitely lapsed due to non-payment of fees |