MC2091A1 - Procedes pour la preparation de composes a action anti-inflammatoire et de formulations pharmaceutiques les contenant - Google Patents

Procedes pour la preparation de composes a action anti-inflammatoire et de formulations pharmaceutiques les contenant

Info

Publication number
MC2091A1
MC2091A1 MC902102A MC2102A MC2091A1 MC 2091 A1 MC2091 A1 MC 2091A1 MC 902102 A MC902102 A MC 902102A MC 2102 A MC2102 A MC 2102A MC 2091 A1 MC2091 A1 MC 2091A1
Authority
MC
Monaco
Prior art keywords
compounds
processes
preparation
pharmaceutical formulations
formulations containing
Prior art date
Application number
MC902102A
Other languages
English (en)
Inventor
Paul Jackson William
Anthony Salmon John
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898902472A external-priority patent/GB8902472D0/en
Priority claimed from GB898919314A external-priority patent/GB8919314D0/en
Priority claimed from GB898924867A external-priority patent/GB8924867D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of MC2091A1 publication Critical patent/MC2091A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
MC902102A 1989-02-03 1990-02-02 Procedes pour la preparation de composes a action anti-inflammatoire et de formulations pharmaceutiques les contenant MC2091A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898902472A GB8902472D0 (en) 1989-02-03 1989-02-03 Anti-inflammatory aryl derivatives
GB898919314A GB8919314D0 (en) 1989-08-25 1989-08-25 Anti-inflammatory aryl derivatives
GB898924867A GB8924867D0 (en) 1989-11-03 1989-11-03 Anti-inflammatory aryl derivatives

Publications (1)

Publication Number Publication Date
MC2091A1 true MC2091A1 (fr) 1991-02-15

Family

ID=27264299

Family Applications (1)

Application Number Title Priority Date Filing Date
MC902102A MC2091A1 (fr) 1989-02-03 1990-02-02 Procedes pour la preparation de composes a action anti-inflammatoire et de formulations pharmaceutiques les contenant

Country Status (16)

Country Link
EP (1) EP0384594B1 (fr)
JP (1) JPH02270855A (fr)
KR (1) KR900012892A (fr)
AT (1) ATE96427T1 (fr)
AU (1) AU624896B2 (fr)
CA (1) CA2009201A1 (fr)
DE (1) DE69004119T2 (fr)
DK (1) DK0384594T3 (fr)
ES (1) ES2060015T3 (fr)
FI (1) FI900536A0 (fr)
HU (1) HU208523B (fr)
IL (1) IL93259A0 (fr)
MC (1) MC2091A1 (fr)
NO (1) NO171906C (fr)
NZ (1) NZ232350A (fr)
PT (1) PT93049A (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120752A (en) * 1989-12-28 1992-06-09 Abbott Laboratories Cyclopropyl derivative lipoxygenase inhibitors
US5476873A (en) * 1990-07-25 1995-12-19 Abbott Laboratories Acetylene derivatives having lipoxygenase inhibitory activity
JPH06256285A (ja) * 1990-12-11 1994-09-13 Pfizer Pharmaceut Co Ltd ヒドロキサム酸誘導体およびその用途
US5130485A (en) * 1991-04-23 1992-07-14 Eli Lilly And Company N-hydroxy-N-(3-(2-substituted phenyl)prop-2-enyl)ureas and thioureas useful as 5-lipoxygenase inhibiting agents
US5283361A (en) * 1991-04-23 1994-02-01 Eli Lilly And Company N-hydroxy-N-[3-[2-(halophenylthio)phenyl]prop-2-enyl]ureas as lipoxygenase inhibitors
US5140047A (en) * 1991-05-03 1992-08-18 Smithkline Beecham Corporation Lipoxygenase inhibitors
DE4204686A1 (de) * 1992-02-17 1993-08-19 Gruenenthal Gmbh Imidazolylphenolderivate, diese enthaltende arzneimittel sowie ein verfahren zur herstellung dieser verbindungen und arzneimitteln
US5326787A (en) * 1992-05-12 1994-07-05 Abbott Laboratories Cycloalkyl N-hydroxy derivatives having lipoxygenase inhibitory activity
GB9308652D0 (en) * 1993-04-27 1993-06-09 Wellcome Found Anti-inflammatory compounds
TW418089B (en) * 1993-08-19 2001-01-11 Pfizer Pharmaceutical composition comprising phenoxyphenyl cyclopentenyl hydroxyureas (the dextrorotary isomers)
US5468760A (en) * 1993-11-08 1995-11-21 American Home Products Corporation Aralkyl-N-hydroxyureas as inhibitors of 5-lipoxygenase and oxidation of low density lipoprotein
US5428048A (en) * 1993-11-08 1995-06-27 American Home Products Corporation Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents
US5459154A (en) * 1993-11-08 1995-10-17 American Home Products Corporation N-hydroxyureas as 5-lipoxygenase inhibitors and inhibitors of oxidative modification of low density lipoprotein
EP0891772A3 (fr) * 1997-06-18 1999-05-19 Santen Pharmaceutical Co., Ltd. Agent thérapeutique pour le traitement des maladies rheumatismales contenant un agent anti-inflammatoire non stéroide et un dérivé d'acide phénylpropionique
CA2465261A1 (fr) * 2001-10-24 2003-05-01 The Regents Of The University Of California Identification de 5-lipoxydase en tant qu'oligogene favorisant l'atherosclerose
WO2013007371A2 (fr) * 2011-07-13 2013-01-17 Eth Zurich Résolution cinétique d'amines chirales

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2559699B2 (ja) * 1985-03-16 1996-12-04 ザ ウエルカム フアウンデ−シヨン リミテツド 新規なアリ−ル誘導体
US4728670A (en) * 1986-06-04 1988-03-01 E. R. Squibb & Sons, Inc. Biphenyl hydroxamic acids
US4897422A (en) * 1987-02-10 1990-01-30 Abbott Laboratories Lipoxygenase inhibiting compounds
EP0292699B1 (fr) * 1987-04-24 1994-03-23 Abbott Laboratories Dérivés d'urée inhibiteurs de lipoxygénase
PL154186B1 (en) * 1987-07-15 1991-07-31 Wellcome Found Method for manufacturing arylic derivatives of the hydroxamic acid

Also Published As

Publication number Publication date
ES2060015T3 (es) 1994-11-16
CA2009201A1 (fr) 1990-08-03
IL93259A0 (en) 1990-11-29
NO900504L (no) 1990-08-06
PT93049A (pt) 1990-08-31
DE69004119D1 (de) 1993-12-02
JPH02270855A (ja) 1990-11-05
EP0384594A1 (fr) 1990-08-29
HU900656D0 (en) 1990-04-28
HU208523B (en) 1993-11-29
EP0384594B1 (fr) 1993-10-27
AU4908890A (en) 1990-08-09
NO171906B (no) 1993-02-08
ATE96427T1 (de) 1993-11-15
NO171906C (no) 1993-05-19
DE69004119T2 (de) 1994-03-24
FI900536A0 (fi) 1990-02-02
KR900012892A (ko) 1990-09-03
DK0384594T3 (da) 1993-12-06
NO900504D0 (no) 1990-02-02
NZ232350A (en) 1992-04-28
AU624896B2 (en) 1992-06-25
HUT53071A (en) 1990-09-28

Similar Documents

Publication Publication Date Title
MC2091A1 (fr) Procedes pour la preparation de composes a action anti-inflammatoire et de formulations pharmaceutiques les contenant
CA2029599A1 (fr) Medicaments contenant comme substance active des acides carboxyliques renfermant du soufre
FI872864A (fi) Menetelmä farmaseuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi
SE8804692L (sv) Nya 17b-oh-19-nor-steroider substituerade i 17 -staellning, foerfarande foer framstaellning daerav, anvaendning daerav som laekemedel och farmaceutiska kompositioner innehaallande dem
FR2698788B1 (fr) Composition pharmaceutique effervescente contenant de l'ibuprofène et son procédé de préparation.
IT1226727B (it) Farmaci precursori della dopamina.
NZ225408A (en) Acetohydroxamic acid derivatives and compositions thereof
IL92358A0 (en) Diaryl compounds,their preparation and pharmaceutical compositions containing them
KR880007074A (ko) 의약품
DE68904102D1 (de) Antivirale tetrahydroimidazo(1,4)benzodiazepin-2-one.
FR2712809B1 (fr) Nouvelle composition pharmaceutique destinée à la préparation d'une poudre stable contenant, à titre d'ingrédient actif, une association d'acide acétylsalicylique et de métoclopramide.
ATE40127T1 (de) 1,5-benzothiazepinderivate, verfahren zu ihrer herstellung und arzneimittel.
HU9500175D0 (en) Pharmacologically active alpha-[tertiary-aminomethyl]-benzenemethanol derivatives
DK644487A (da) Farmaceutisk praeparat indeholdende en 2-oxo-imidazolidinforbindelse
JO1679B1 (en) A new, therapeutically active compound and method for preparing it
TH8696A (th) สารประกอบแอริลซึ่งต้านการอักเสบ
ES8300709A1 (es) Un metodo para la preparacion de derivados de pirazolidinona
JO1660B1 (en) Benzimidazole compounds are a therapeutically effective substitute for chlorine and processes for preparing and using them
TH6256A (th) อนุพันธ์ แอริล สารต่อต้านการอักเสบ

Legal Events

Date Code Title Description
YP Annual fee paid