MC1985A1 - AMINO ACID DERIVATIVES - Google Patents

AMINO ACID DERIVATIVES

Info

Publication number: MC1985A1
Authority: MC; Monaco
Prior art keywords: amino acid; acid derivatives; derivatives; amino; acid
Prior art date: 1987-10-06

Application number

MC882008A

Other languages

French (fr)

Inventor

Branca Quirico

Edenhofer Albrecht

Gutknecht Eva-Maria

Neidhart Werner

Ramuz Henri

Wostl Wolfgang

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-06

Filing date

1988-10-03

Publication date

1989-11-23

1988-10-03 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1989-11-23 Publication of MC1985A1 publication Critical patent/MC1985A1/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic

MC882008A 1987-10-06 1988-10-03 AMINO ACID DERIVATIVES MC1985A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH390387		1987-10-06

Publications (1)

Publication Number	Publication Date
MC1985A1 true MC1985A1 (en)	1989-11-23

Family

ID=4265984

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MC882008A MC1985A1 (en)	1987-10-06	1988-10-03	AMINO ACID DERIVATIVES

Country Status (14)

Country	Link
EP (1)	EP0310918A3 (en)
JP (1)	JPH02256658A (en)
KR (1)	KR890006572A (en)
AU (1)	AU627156B2 (en)
DK (1)	DK523288A (en)
FI (1)	FI884598A (en)
HU (1)	HUT49322A (en)
IL (1)	IL87871A0 (en)
MC (1)	MC1985A1 (en)
NO (1)	NO884434L (en)
NZ (1)	NZ226395A (en)
PT (1)	PT88679A (en)
YU (1)	YU185188A (en)
ZA (1)	ZA887322B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ220173A (en) *	1986-05-09	1990-01-29	Dainippon Pharmaceutical Co	Tripeptide derivatives as antihypertensive agents;processes for their preparation and pharmaceutical compositions thereof
US4895834A (en) *	1986-12-15	1990-01-23	Warner-Lambert Company	Renin inhibitors III
US5023236A (en) *	1988-04-07	1991-06-11	Corvas, Inc.	Factor VII/VIIA active site inhibitors
EP0391180A3 (en) *	1989-04-04	1991-04-03	F. Hoffmann-La Roche Ag	Peptide derivatives of amino acids having a renin-inhibiting effect
CA2012901A1 (en) *	1989-04-05	1990-10-05	Quirico Branca	Amino acid derivatives
ES2086341T3 (en) *	1989-09-12	1996-07-01	Hoechst Ag	DERIVATIVES OF AMINO ACIDS WITH RENINE INHIBITING PROPERTIES, PROCEDURE FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE.
DE4008403A1 (en) *	1990-03-16	1991-09-19	Merck Patent Gmbh	GLYKOLSAEUREDERIVATE
US5516784A (en) *	1991-08-13	1996-05-14	Schering Corporation	Anti-HIV (AIDS) agents
US5422349A (en) *	1992-08-14	1995-06-06	G. D. Seale & Co.	Morpholino-oxazinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension
US5693815A (en) *	1993-01-17	1997-12-02	Schering Corporation	Peptides
US5563127A (en) *	1993-03-24	1996-10-08	The Dupont Merck Pharmaceutical Company	Boronic acid and ester inhibitors of thrombin
FR2741066B1 (en) *	1995-11-14	1997-12-12	Rhone Poulenc Rorer Sa	NEW TRANSFECTION AGENTS AND THEIR PHARMACEUTICAL APPLICATIONS
FR2752422B1 (en) *	1996-08-16	1998-11-06	Lipha	PHARMACEUTICAL COMPOSITION CONTAINING 4-OXO-BUTANOIC ACIDS
YU68900A (en) *	1998-05-12	2002-12-10	Warner-Lambert Company	Combinations of protein farnesyltransferase and hmg coa reductase inhibitors and their use to theat cancer
AU2008247488B2 (en) *	2007-05-04	2014-02-27	Marina Biotech, Inc.	Amino acid lipids and uses thereof
GB0919194D0 (en)	2009-11-02	2009-12-16	Lytix Biopharma As	Compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4652551A (en) *	1984-06-22	1987-03-24	Abbott Laboratories	Renin inhibiting compounds
DK34086A (en) *	1985-01-23	1986-07-24	Abbott Lab	PEPTIDYLAMINODIOLS
IL81234A (en) *	1986-01-16	1992-09-06	Abbott Lab	Peptidylaminodiols,process for their preparation and pharmaceutical compositions comprising them
US4792555A (en) *	1987-03-20	1988-12-20	American Home Products Corporation	Phospholipase A2 inhibitors

1988
- 1988-09-20 DK DK523288A patent/DK523288A/en not_active Application Discontinuation
- 1988-09-27 EP EP19880115878 patent/EP0310918A3/en not_active Withdrawn
- 1988-09-29 IL IL87871A patent/IL87871A0/en unknown
- 1988-09-29 NZ NZ226395A patent/NZ226395A/en unknown
- 1988-09-29 ZA ZA887322A patent/ZA887322B/en unknown
- 1988-09-30 AU AU23307/88A patent/AU627156B2/en not_active Ceased
- 1988-10-03 MC MC882008A patent/MC1985A1/en unknown
- 1988-10-03 HU HU885114A patent/HUT49322A/en unknown
- 1988-10-04 YU YU01851/88A patent/YU185188A/en unknown
- 1988-10-05 KR KR1019880012964A patent/KR890006572A/en not_active Application Discontinuation
- 1988-10-05 NO NO88884434A patent/NO884434L/en unknown
- 1988-10-06 PT PT88679A patent/PT88679A/en unknown
- 1988-10-06 JP JP63252886A patent/JPH02256658A/en active Pending
- 1988-10-06 FI FI884598A patent/FI884598A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK523288A (en)	1989-04-07
HUT49322A (en)	1989-09-28
KR890006572A (en)	1989-06-14
YU185188A (en)	1990-12-31
ZA887322B (en)	1989-06-28
NO884434D0 (en)	1988-10-05
AU2330788A (en)	1989-06-08
JPH02256658A (en)	1990-10-17
EP0310918A3 (en)	1990-12-12
FI884598A (en)	1989-04-07
EP0310918A2 (en)	1989-04-12
DK523288D0 (en)	1988-09-20
NZ226395A (en)	1991-12-23
AU627156B2 (en)	1992-08-20
NO884434L (en)	1989-04-07
IL87871A0 (en)	1989-03-31
FI884598A0 (en)	1988-10-06
PT88679A (en)	1989-07-31

Legal Events

Date	Code	Title	Description
1991-08-20	YP	Annual fee paid

Publication	Publication Date	Title
MC2040A1 (en)	1990-05-30	AMINO ACID DERIVATIVES
MC2022A1 (en)	1990-02-23	AMINO ACID DERIVATIVES
MC2151A1 (en)	1992-03-10	AMINO ACID DERIVATIVES
MC2106A1 (en)	1991-03-11	AMINO ACID DERIVATIVES
DK340088A (en)	1988-12-23	AMINO ACID DERIVATIVES
MC2103A1 (en)	1991-03-11	AMINO ACID DERIVATIVES
DE59008394D1 (en)	1995-03-16	Amino acid amide derivatives.
NO920417D0 (en)	1992-01-31	amino acid derivative
DE122005000012I2 (en)	2006-02-09	N- (pyrrolo (2-3-d) pyrimidin-3-ylacyl-glutamic acid derivatives {
MA26449A1 (en)	2004-12-20	AMINO ACID DERIVATIVES.
FR2609998B1 (en)	1994-04-15	NOVEL ANTIOXIDANT SUBSTANCES DERIVED FROM AMINO ACIDS
IT1191807B (en)	1988-03-23	MIXTURES-MOTHER FOR THE OPACIZATION OF POLYAMIDES
DK414389D0 (en)	1989-08-23	PHARMACEUTICAL PREPARATION CONTAINING AN AMINO ACID DERIVATIVE WITH PURINE-INHIBITORIAL EFFECT
MC1985A1 (en)	1989-11-23	AMINO ACID DERIVATIVES
MC2107A1 (en)	1991-03-11	AMINO ACID DERIVATIVES
DK0425925T3 (en)	1994-11-21	Substituted amino acid amide derivatives as well as their preparation and use
MC2264A1 (en)	1993-04-26	AMINO ACID DERIVATIVES
IT8722619A0 (en)	1987-11-13	AMINO PEROXICARBOXYLIC DERIVATIVES
MC1981A1 (en)	1989-11-23	CATECHOL CARBOXYLIC ACID DERIVATIVES
MC1960A1 (en)	1989-06-30	HYDROCINNAMIC ACID DERIVATIVES
DK702688D0 (en)	1988-12-16	EPIPODOPHYLLOTOXIN-GLUCOSIDE 4'-ACYLD DERIVATIVES
PT75949B (en)	1985-10-04	PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES IN N- (VINBLASTINOIL-23)
DE69018816T2 (en)	1995-11-16	AMINO ACID DERIVATIVES.
MC2109A1 (en)	1991-03-11	Amino acid derivatives
FR2508036B1 (en)	1985-12-13	NOVEL NA-3-CYANO-PROPANOIC AMINO ACID DERIVATIVES AND APPLICATION THEREOF