MC1409A1 - Procede pour la preparation de derives de benzazepine - Google Patents

Procede pour la preparation de derives de benzazepine

Info

Publication number
MC1409A1
MC1409A1 MC811533A MC1533A MC1409A1 MC 1409 A1 MC1409 A1 MC 1409A1 MC 811533 A MC811533 A MC 811533A MC 1533 A MC1533 A MC 1533A MC 1409 A1 MC1409 A1 MC 1409A1
Authority
MC
Monaco
Prior art keywords
preparation
benzazepine derivatives
benzazepine
derivatives
Prior art date
Application number
MC811533A
Other languages
English (en)
Inventor
Rodney Ian Fryer
Eugene J Trybulski
Armin Walser
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1409A1 publication Critical patent/MC1409A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • C07C45/305Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/68Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
    • C07C63/72Polycyclic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
MC811533A 1980-08-05 1981-08-04 Procede pour la preparation de derives de benzazepine MC1409A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17555580A 1980-08-05 1980-08-05
US06/286,124 US4354973A (en) 1980-08-05 1981-07-23 Pyrrolo[3,4-d][2]benzazepines

Publications (1)

Publication Number Publication Date
MC1409A1 true MC1409A1 (fr) 1982-07-16

Family

ID=26871324

Family Applications (1)

Application Number Title Priority Date Filing Date
MC811533A MC1409A1 (fr) 1980-08-05 1981-08-04 Procede pour la preparation de derives de benzazepine

Country Status (25)

Country Link
US (1) US4354973A (fr)
EP (1) EP0045519B1 (fr)
AR (1) AR230639A1 (fr)
AT (1) ATE13888T1 (fr)
AU (1) AU545298B2 (fr)
CA (1) CA1174674A (fr)
CH (1) CH648849A5 (fr)
DE (2) DE3171021D1 (fr)
DK (1) DK347681A (fr)
ES (4) ES8300765A1 (fr)
FI (1) FI71149C (fr)
FR (1) FR2488257A1 (fr)
GB (1) GB2083460B (fr)
HU (1) HU188071B (fr)
IE (1) IE51466B1 (fr)
IL (1) IL63487A (fr)
IT (1) IT1138133B (fr)
LU (1) LU83531A1 (fr)
MC (1) MC1409A1 (fr)
NL (1) NL8103655A (fr)
NO (1) NO812647L (fr)
NZ (1) NZ197920A (fr)
PH (1) PH16814A (fr)
PT (1) PT73481B (fr)
SE (1) SE8104659L (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ204242A (en) * 1982-05-18 1986-08-08 Hoffmann La Roche 8-halo-6-phenyl-2,3-dihydro-1h,4h-pyrrolo(3,4-d)(2)benzazepine-(1-or 3-ones or 1,3-diones)
US4436662A (en) 1982-06-28 1984-03-13 Hoffmann-La Roche Inc. Pyrrolo[3,4-d][2]benzazepinones
US5098901A (en) * 1991-09-10 1992-03-24 Sterling Drug Inc. Imidazo [1,2-b][2]benzazepine and pyrimido [1,2-b][2]benzazepine antiarrhythmic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3523947A (en) * 1966-11-23 1970-08-11 Hoffmann La Roche 1-cyclic amidine-5-aryl-1,4-benzodiazepine and process
US3947585A (en) * 1974-06-03 1976-03-30 Ciba-Geigy Corporation Pyrazolobenzazepines
US4022801A (en) * 1974-06-03 1977-05-10 Ciba-Geigy Corporation Pyrazolobenzazepines
US4169150A (en) * 1975-11-12 1979-09-25 Teijin Limited Benzodiazepine derivatives and pharmaceutical compositions containing said derivatives

Also Published As

Publication number Publication date
EP0045519B1 (fr) 1985-06-19
ATE13888T1 (de) 1985-07-15
LU83531A1 (de) 1983-06-08
NL8103655A (nl) 1982-03-01
CA1174674A (fr) 1984-09-18
FR2488257B1 (fr) 1984-04-27
IT8123347A0 (it) 1981-08-03
ES513622A0 (es) 1983-04-01
IE51466B1 (en) 1986-12-24
ES504525A0 (es) 1982-11-16
ES8300765A1 (es) 1982-11-16
EP0045519A3 (en) 1982-03-31
GB2083460B (en) 1984-07-11
US4354973A (en) 1982-10-19
DE3171021D1 (en) 1985-07-25
FI71149C (fi) 1986-11-24
HU188071B (en) 1986-03-28
AU545298B2 (en) 1985-07-11
FI71149B (fi) 1986-08-14
AU7382581A (en) 1982-02-11
ES8304984A1 (es) 1983-04-01
NZ197920A (en) 1984-11-09
SE8104659L (sv) 1982-02-06
PT73481A (en) 1981-09-01
IL63487A0 (en) 1981-11-30
DE3131064A1 (de) 1982-04-08
IL63487A (en) 1987-01-30
GB2083460A (en) 1982-03-24
NO812647L (no) 1982-02-08
ES513621A0 (es) 1983-04-01
EP0045519A2 (fr) 1982-02-10
FI812416L (fi) 1982-02-06
PT73481B (en) 1983-07-06
ES513620A0 (es) 1983-04-01
CH648849A5 (de) 1985-04-15
IT1138133B (it) 1986-09-17
IE811775L (en) 1982-02-05
ES8304985A1 (es) 1983-04-01
DK347681A (da) 1982-02-06
ES8304983A1 (es) 1983-04-01
AR230639A1 (es) 1984-05-31
FR2488257A1 (fr) 1982-02-12
PH16814A (en) 1984-03-06

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Legal Events

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