MA55380A - Dérivé hétéroaryle, son procédé de production et composition pharmaceutique le comprenant en tant que constituant efficace - Google Patents
Dérivé hétéroaryle, son procédé de production et composition pharmaceutique le comprenant en tant que constituant efficaceInfo
- Publication number
- MA55380A MA55380A MA055380A MA55380A MA55380A MA 55380 A MA55380 A MA 55380A MA 055380 A MA055380 A MA 055380A MA 55380 A MA55380 A MA 55380A MA 55380 A MA55380 A MA 55380A
- Authority
- MA
- Morocco
- Prior art keywords
- production
- pharmaceutical composition
- effective constituent
- heteroaryl derivative
- heteroaryl
- Prior art date
Links
- 239000000470 constituent Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20190031269 | 2019-03-19 | ||
KR20190134472 | 2019-10-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA55380A true MA55380A (fr) | 2022-01-26 |
Family
ID=72521153
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA055380A MA55380A (fr) | 2019-03-19 | 2020-03-19 | Dérivé hétéroaryle, son procédé de production et composition pharmaceutique le comprenant en tant que constituant efficace |
Country Status (15)
Country | Link |
---|---|
US (2) | US20220162203A1 (fr) |
EP (1) | EP3943491A4 (fr) |
JP (2) | JP7109013B2 (fr) |
KR (2) | KR102318875B1 (fr) |
CN (3) | CN114605400A (fr) |
AU (2) | AU2020240382B2 (fr) |
BR (1) | BR112021018704B1 (fr) |
CA (1) | CA3134261A1 (fr) |
IL (2) | IL299831A (fr) |
MA (1) | MA55380A (fr) |
MX (1) | MX2021011160A (fr) |
NZ (1) | NZ781366A (fr) |
SG (1) | SG11202110376XA (fr) |
WO (1) | WO2020190119A1 (fr) |
ZA (1) | ZA202107889B (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20220289733A1 (en) * | 2019-03-19 | 2022-09-15 | Voronoi Inc. | Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component |
JP7109013B2 (ja) | 2019-03-19 | 2022-07-29 | ボロノイ インコーポレイテッド | ヘテロアリール誘導体、ヘテロアリール誘導体の生成方法、およびヘテロアリール誘導体を有効成分として含む医薬組成物 |
TW202227425A (zh) * | 2020-09-18 | 2022-07-16 | 南韓商沃若諾伊生物公司 | 雜芳基衍生物、彼之製法、及包含彼作為活性成份之藥學組成物 |
KR20220085735A (ko) * | 2020-12-14 | 2022-06-22 | 보로노이바이오 주식회사 | 아이소옥사졸리딘 유도체 화합물 및 이의 용도 |
WO2022234965A1 (fr) * | 2021-05-07 | 2022-11-10 | 주식회사 보로노이 | Dérivé hétéroaryle, son procédé de préparation et composition pharmaceutique le comprenant en tant que principe actif |
JP2024519626A (ja) * | 2021-05-17 | 2024-05-21 | ボロノイ インコーポレイテッド | ヘテロアリール誘導体化合物およびその用途{Heteroaryl derivative compounds,and uses thereof} |
KR102563834B1 (ko) * | 2021-06-28 | 2023-08-04 | 순천대학교 산학협력단 | 세포자멸사를 유도하는 신규한 화합물 및 이를 포함하는 항암용 조성물 |
WO2024096624A1 (fr) * | 2022-11-03 | 2024-05-10 | Voronoi Inc. | Sels de fumarate, tartrate, malate et de citrate d'un inhibiteur d'egfr |
WO2024097848A1 (fr) | 2022-11-03 | 2024-05-10 | Oric Pharmaceuticals, Inc. | Sels de malonate et de glycolate d'un inhibiteur d'egfr |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60134679D1 (de) | 2000-10-20 | 2008-08-14 | Eisai R&D Man Co Ltd | Stickstoff enthaltende aromatische Heterozyklen |
US8084457B2 (en) | 2003-09-15 | 2011-12-27 | Lead Discovery Center Gmbh | Pharmaceutically active 4,6-disubstituted aminopyrimidine derivatives as modulators of protein kinases |
WO2006125616A2 (fr) | 2005-05-25 | 2006-11-30 | Ingenium Pharmaceuticals Ag | Methodes de traitement de la douleur |
TW200804364A (en) | 2006-02-22 | 2008-01-16 | Boehringer Ingelheim Int | New compounds |
JP2010522188A (ja) | 2007-03-20 | 2010-07-01 | スミスクライン ビーチャム コーポレーション | 化合物 |
TWI377944B (en) | 2007-06-05 | 2012-12-01 | Hanmi Holdings Co Ltd | Novel amide derivative for inhibiting the growth of cancer cells |
JP2011102241A (ja) | 2008-03-04 | 2011-05-26 | Dainippon Sumitomo Pharma Co Ltd | 新規1−アミノカルボニルピペリジン誘導体 |
AU2010284255B2 (en) | 2009-08-17 | 2016-11-17 | Memorial Sloan-Kettering Cancer Center | Heat shock protein binding compounds, compositions, and methods for making and using same |
KR101401664B1 (ko) | 2011-11-15 | 2014-06-11 | 중앙대학교 산학협력단 | 신경줄기세포 분화조절제용 신규 피리미딘-2,4-디아민 유도체 및 이의 의학적 용도 |
ES2668479T3 (es) | 2012-01-20 | 2018-05-18 | Genosco | Compuestos de pirimidina sustituidos y su uso como inhibidores de SYK |
US20150166591A1 (en) | 2012-05-05 | 2015-06-18 | Ariad Pharmaceuticals, Inc. | Methods and compositions for raf kinase mediated diseases |
WO2014055928A2 (fr) | 2012-10-04 | 2014-04-10 | University Of Utah Research Foundation | Analogues de n-(3-(pyrimidin-4-yl)phényl) substitué utilisés en tant qu'inhibiteurs de récepteur tyrosine kinase btk |
EP2769722A1 (fr) | 2013-02-22 | 2014-08-27 | Ruprecht-Karls-Universität Heidelberg | Composés utilisés pour inhiber un assemblage de capside du VIH |
US9434719B2 (en) | 2013-03-14 | 2016-09-06 | Novartis Ag | 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH |
WO2015025936A1 (fr) | 2013-08-22 | 2015-02-26 | 大鵬薬品工業株式会社 | Nouveau composé substitué par une quinoline |
WO2015061247A2 (fr) | 2013-10-21 | 2015-04-30 | Merck Patent Gmbh | Composés hétéroaryle servant d'inhibiteurs de la btk et leurs utilisations |
KR20150047855A (ko) | 2013-10-25 | 2015-05-06 | 한미약품 주식회사 | 단백질 카이네이즈 억제 효과를 갖는 2-사이아노-아크릴아마이드 유도체 |
EP3143015B1 (fr) | 2014-05-13 | 2019-02-20 | ARIAD Pharmaceuticals, Inc. | Composés hétéroaryl pour l'inhibition de kinase |
DK3157916T3 (en) | 2014-06-19 | 2019-03-18 | Ariad Pharma Inc | HETEROARYL COMPOUNDS FOR CHINESE INHIBITION |
PL3205650T3 (pl) * | 2014-10-11 | 2021-12-06 | Shanghai Hansoh Biomedical Co., Ltd. | Inhibitor EGFR i jego otrzymywanie i zastosowanie |
SG11201701960XA (en) | 2014-10-13 | 2017-04-27 | Yuhan Corp | Compounds and compositions for modulating egfr mutant kinase activities |
EP3206691B1 (fr) * | 2014-10-14 | 2018-09-19 | Sunshine Lake Pharma Co., Ltd. | Composés hétéroaryle substitués et leurs méthodes d'utilisation |
CN107835811B (zh) | 2015-07-16 | 2019-11-08 | 正大天晴药业集团股份有限公司 | 苯胺嘧啶衍生物及其用途 |
CN106478607B (zh) * | 2015-08-28 | 2019-05-24 | 广东东阳光药业有限公司 | 取代的杂芳基化合物及其组合物和用途 |
CN106132957B (zh) * | 2015-08-31 | 2018-06-12 | 无锡双良生物科技有限公司 | 2-芳胺基吡啶、嘧啶或三嗪衍生物及其制备方法和用途 |
US10709692B2 (en) | 2015-12-04 | 2020-07-14 | Denali Therapeutics Inc. | Isoxazolidine derived inhibitors of receptor interacting protein kinase 1 (RIPK1) |
EP3399968B8 (fr) * | 2016-01-07 | 2021-12-01 | Xuanzhu Biopharmaceutical Co., Ltd. | Inhibiteurs sélectifs de mutants cliniquement importants de la tyrosine kinase de l'egfr |
US11203576B2 (en) | 2016-03-11 | 2021-12-21 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Aurora kinase and Janus kinase inhibitors for prevention of graft versus host disease |
US11072607B2 (en) | 2016-12-16 | 2021-07-27 | Genentech, Inc. | Inhibitors of RIP1 kinase and methods of use thereof |
JP7028900B2 (ja) | 2017-06-13 | 2022-03-02 | ベイジン アダマドル バイオテクノロジー リミテッド ライアビリティ カンパニー | アミノピリミジン化合物、その調製方法、およびその使用 |
CA3068854A1 (fr) * | 2017-07-05 | 2019-01-10 | Cs Pharmatech Limited | Inhibiteurs selectifs de mutants cliniquement importants de la tyrosine kinase de l'egfr |
CA3079786A1 (fr) | 2017-10-24 | 2019-05-02 | The Broad Institute, Inc. | Derives de 4h-pyrrolo[3,2-c]pyridin-4-one |
TWI798334B (zh) | 2018-01-31 | 2023-04-11 | 大陸商迪哲(江蘇)醫藥股份有限公司 | Erbb/btk抑制劑 |
CN108191774B (zh) | 2018-01-31 | 2022-05-24 | 中国药科大学 | 一类杂环化合物、其制备方法和用途 |
KR20190108079A (ko) | 2018-03-13 | 2019-09-23 | 보로노이바이오 주식회사 | 2,4,5-치환된 피리미딘 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 |
WO2019177374A1 (fr) | 2018-03-13 | 2019-09-19 | 포로노이바이오 주식회사 | Dérivé de pyrimidine substitué en positions 2, 4 et 5, son procédé de préparation, et composition pharmaceutique le comprenant en tant que principe actif pour la prévention ou le traitement du cancer ou d'une maladie inflammatoire |
CA3099737A1 (fr) | 2018-05-14 | 2019-11-21 | Ariad Pharmaceuticals, Inc. | Sels pharmaceutiques de derives de pyrimidine et methode de traitement d'affections |
CN109280048A (zh) | 2018-11-16 | 2019-01-29 | 江西科技师范大学 | 一种含取代苯基丙烯酰胺结构的嘧啶类化合物及其应用 |
CN109608394A (zh) | 2018-12-03 | 2019-04-12 | 湖南大学 | 氮杂芳胺类化合物的合成方法和氮杂芳胺类化合物 |
JP7109013B2 (ja) | 2019-03-19 | 2022-07-29 | ボロノイ インコーポレイテッド | ヘテロアリール誘導体、ヘテロアリール誘導体の生成方法、およびヘテロアリール誘導体を有効成分として含む医薬組成物 |
-
2020
- 2020-03-19 JP JP2022504023A patent/JP7109013B2/ja active Active
- 2020-03-19 WO PCT/KR2020/095044 patent/WO2020190119A1/fr active Application Filing
- 2020-03-19 CN CN202210215237.6A patent/CN114605400A/zh active Pending
- 2020-03-19 MA MA055380A patent/MA55380A/fr unknown
- 2020-03-19 CN CN202211226875.4A patent/CN115838369A/zh active Pending
- 2020-03-19 SG SG11202110376XA patent/SG11202110376XA/en unknown
- 2020-03-19 NZ NZ781366A patent/NZ781366A/en unknown
- 2020-03-19 US US17/440,630 patent/US20220162203A1/en active Pending
- 2020-03-19 BR BR112021018704-9A patent/BR112021018704B1/pt active IP Right Grant
- 2020-03-19 KR KR1020200033737A patent/KR102318875B1/ko active IP Right Grant
- 2020-03-19 MX MX2021011160A patent/MX2021011160A/es unknown
- 2020-03-19 CA CA3134261A patent/CA3134261A1/fr active Pending
- 2020-03-19 IL IL299831A patent/IL299831A/en unknown
- 2020-03-19 CN CN202080022186.4A patent/CN113993866B/zh active Active
- 2020-03-19 EP EP20774059.8A patent/EP3943491A4/fr active Pending
- 2020-03-19 AU AU2020240382A patent/AU2020240382B2/en active Active
-
2021
- 2021-09-19 IL IL286471A patent/IL286471B2/en unknown
- 2021-10-15 ZA ZA2021/07889A patent/ZA202107889B/en unknown
- 2021-10-21 KR KR1020210141386A patent/KR102564533B1/ko active IP Right Grant
- 2021-11-08 US US17/521,711 patent/US11466000B2/en active Active
-
2022
- 2022-07-07 JP JP2022109721A patent/JP7394298B2/ja active Active
- 2022-08-01 AU AU2022211789A patent/AU2022211789A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CN115838369A (zh) | 2023-03-24 |
CN113993866A (zh) | 2022-01-28 |
EP3943491A4 (fr) | 2022-11-23 |
IL286471B2 (en) | 2023-08-01 |
AU2020240382A1 (en) | 2021-11-11 |
EP3943491A1 (fr) | 2022-01-26 |
AU2022211789A1 (en) | 2022-08-25 |
CN114605400A (zh) | 2022-06-10 |
BR112021018704B1 (pt) | 2023-01-10 |
AU2020240382B2 (en) | 2022-08-25 |
US20220073505A1 (en) | 2022-03-10 |
CN113993866B (zh) | 2022-10-28 |
US11466000B2 (en) | 2022-10-11 |
JP2022522250A (ja) | 2022-04-14 |
IL286471B1 (en) | 2023-04-01 |
ZA202107889B (en) | 2024-02-28 |
MX2021011160A (es) | 2022-02-10 |
IL286471A (en) | 2021-12-01 |
JP7109013B2 (ja) | 2022-07-29 |
BR112021018704A2 (fr) | 2021-11-23 |
US20220162203A1 (en) | 2022-05-26 |
SG11202110376XA (en) | 2021-10-28 |
IL299831A (en) | 2023-03-01 |
KR102564533B1 (ko) | 2023-08-08 |
WO2020190119A1 (fr) | 2020-09-24 |
KR20210130123A (ko) | 2021-10-29 |
KR20200111644A (ko) | 2020-09-29 |
CA3134261A1 (fr) | 2020-09-24 |
JP2022125283A (ja) | 2022-08-26 |
JP7394298B2 (ja) | 2023-12-08 |
KR102318875B1 (ko) | 2021-11-01 |
NZ781366A (en) | 2022-08-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA55380A (fr) | Dérivé hétéroaryle, son procédé de production et composition pharmaceutique le comprenant en tant que constituant efficace | |
BR112017019287A2 (pt) | composto, composição farmaceuticamente aceitável, método de tratamento de câncer, processo para preparar o composto da fórmula i, método para tratar câncer, e kit | |
BR112019006106A2 (pt) | formulação carregada com canabinoide, processo para preparar a formulação carregada com canabinoide, composições farmacêutica e nutracêutica, e, método de tratamento de um indivíduo sofrendo de uma enfermidade ou um distúrbio. | |
EP3312177A4 (fr) | Composé dérivé tricyclique, son procédé de préparation, et composition pharmaceutique le contenant | |
BR112017020886A2 (pt) | processo para criação de insetos | |
NZ734714A (en) | Methods of purifying cannabinoids, compositions and kits thereof | |
EP3539960A4 (fr) | Composé macrocyclique azoté, son procédé de préparation, sa composition pharmaceutique et son application | |
BR112018013174A2 (pt) | composição e método para crescimento de cabelo | |
EP3636646A4 (fr) | Dérivés d'hétéroaryle pyrazole, leur procédé de préparation et leur application médicale | |
EP3287463A4 (fr) | Dérivé pyrimidylamino à cycle condensé, son procédé de préparation, et intermédiaire, composition pharmaceutique et applications associées | |
EP3133071A4 (fr) | Dérivé c-aryl indican et composition pharmaceutique correspondante, procédé de préparation associé et utilisations associées | |
EP3279207A4 (fr) | Nouveau composé de 4'-thionucléoside, ainsi que son procédé de préparation, composition pharmaceutique comprenant celui-ci et son application | |
CL2015001772A1 (es) | Composición farmacéutica para el tratamiento de dolor cabeza, y método de preparación de la misma. | |
PT3524609T (pt) | Método para a preparação de derivados de 3-fenil- 2,3,4,8,9,10-hexahidropirano[2,3-f]cromeno, isómeros óticos dos mesmos, e intermediários do processo | |
BR112019005103A2 (pt) | método para determinar a quantidade requerida por plantas de cultura em um campo, método para tratar plantas de cultura em um campo, sistema e produto de programa de computador | |
DK3604304T3 (da) | Pyrrolo-pyridinderivatforbindelse, fremgangsmåde til fremstilling deraf og farmaceutisk sammensætning indeholdende denne som aktiv ingrediens til forebyggelse eller behandling af proteinkinase-relaterede sygdomme | |
EP3623503A4 (fr) | Médicament protéique multispécifique et bibliothèque associée, procédé de préparation associé et application associée | |
EP3766521A4 (fr) | Composition pharmaceutique contenant un dérivé d'acide aminé marqué au 211at, et procédé pour produire ladite composition pharmaceutique | |
EP3670511A4 (fr) | Composé de tétrahydroprotoberbérine, son procédé de préparation, ses utilisations et composition pharmaceutique | |
EP3287456A4 (fr) | Composé de 5-hydroxy-1,7-naphtyridine substitué par aryle ou hétéroaryle, son procédé de préparation et son utilisation pharmaceutique | |
MX2019001225A (es) | Compuesto aromatico heterociclico nitrogenoso, metodo de preparacion del mismo, composicion farmaceutico del mismo y aplicacion del mismo. | |
BR112017001888A2 (pt) | formulações biológicas para instilação intravesical | |
EP3805212A4 (fr) | Composé 3-oxazolinone, procédé de préparation correspondant, et utilisation pharmaceutique associée | |
MA40617B1 (fr) | Formulation comprenant glycopyrrolate, procédé et appareil | |
EP3176164A4 (fr) | Isomère optique de dérivé de 1,4-benzothiazépine-1-oxyde, et composition pharmaceutique préparée à l'aide de celui-ci |