MA52885A - Anticorps anti il-11ra - Google Patents

Anticorps anti il-11ra

Info

Publication number
MA52885A
MA52885A MA052885A MA52885A MA52885A MA 52885 A MA52885 A MA 52885A MA 052885 A MA052885 A MA 052885A MA 52885 A MA52885 A MA 52885A MA 52885 A MA52885 A MA 52885A
Authority
MA
Morocco
Prior art keywords
anti body
Prior art date
Application number
MA052885A
Other languages
English (en)
Inventor
Stuart Alexander Cook
Sebastian Schaefer
Original Assignee
Boehringer Ingelheim Int
Nat Univ Singapore
Singapore Health Serv Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int, Nat Univ Singapore, Singapore Health Serv Pte Ltd filed Critical Boehringer Ingelheim Int
Publication of MA52885A publication Critical patent/MA52885A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/6857Antibody fragments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA052885A 2018-06-13 2019-06-13 Anticorps anti il-11ra MA52885A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1809700.6A GB201809700D0 (en) 2018-06-13 2018-06-13 IL-11 antibodies

Publications (1)

Publication Number Publication Date
MA52885A true MA52885A (fr) 2021-04-21

Family

ID=63042296

Family Applications (1)

Application Number Title Priority Date Filing Date
MA052885A MA52885A (fr) 2018-06-13 2019-06-13 Anticorps anti il-11ra

Country Status (24)

Country Link
US (1) US11084878B2 (fr)
EP (1) EP3806959A1 (fr)
JP (1) JP7437325B2 (fr)
KR (1) KR20210031645A (fr)
CN (1) CN113226471A (fr)
AU (1) AU2019286797A1 (fr)
BR (1) BR112020025502A2 (fr)
CA (1) CA3101401A1 (fr)
CL (1) CL2020003218A1 (fr)
CO (1) CO2020015376A2 (fr)
CR (1) CR20210010A (fr)
DO (1) DOP2020000236A (fr)
EA (1) EA202092605A1 (fr)
EC (1) ECSP21001499A (fr)
GB (1) GB201809700D0 (fr)
IL (1) IL279352A (fr)
JO (1) JOP20200300A1 (fr)
MA (1) MA52885A (fr)
MX (1) MX2020013468A (fr)
PE (1) PE20211500A1 (fr)
PH (1) PH12020552229A1 (fr)
SG (1) SG11202011648UA (fr)
TW (1) TW202016140A (fr)
WO (1) WO2019238884A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201522186D0 (en) 2015-12-16 2016-01-27 Singapore Health Services Pte Ltd And Nat University Of Singapore The Treatment of fibrosis
CA3045871A1 (fr) 2016-12-16 2018-06-21 Singapore Health Services Pte Ltd Anticorps anti-il-11
GB201621439D0 (en) 2016-12-16 2017-02-01 Singapore Health Services Pte Ltd And Nat Univ Of Singapore IL-11Ra Antibodies
CN113677706A (zh) 2019-01-21 2021-11-19 新加坡保健服务私人有限公司 肝毒性的治疗
GB201902419D0 (en) 2019-02-22 2019-04-10 Singapore Health Serv Pte Ltd Treatment of kidney injury
CA3146344A1 (fr) 2019-05-03 2020-11-12 Singapore Health Services Pte. Ltd. Traitement et prevention de maladies metaboliques
GB202009292D0 (en) 2020-06-18 2020-08-05 Singapore Health Serv Pte Ltd Treatment and prevention of disease caused by type IV collagen dysfunction
EP3939999A1 (fr) * 2020-07-14 2022-01-19 Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Anticorps neutralisant la sous-unité alpha du récepteur de l'interleukine 11 (il11ra) et leurs utilisations
GB202017244D0 (en) 2020-10-30 2020-12-16 Nat Univ Singapore Methods to extend health-span and treat age-related diseases
WO2022180172A1 (fr) 2021-02-26 2022-09-01 Bayer Aktiengesellschaft Inhibiteurs de l'il-11 ou de l'il-11ra destinés à être utilisés dans le traitement d'un saignement utérin anormal
KR20240070496A (ko) * 2021-07-02 2024-05-21 레크나 테라퓨틱스 상하이 씨오., 엘티디. 활성화된 간 성상세포(hscs)의 고갈 및 이의 용도
EP4376948A1 (fr) 2021-07-26 2024-06-05 Boehringer Ingelheim International GmbH Traitement et prévention d'une maladie hépatique alcoolique
CN113735975B (zh) * 2021-09-07 2022-08-12 广东东阳光药业有限公司 一种抗il-11r抗体及其应用
WO2023111196A1 (fr) 2021-12-16 2023-06-22 Singapore Health Services Pte. Ltd. Traitement et prévention d'une maladie glomérulaire

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1598364A1 (fr) * 2004-05-21 2005-11-23 AGIRx Limited Recepteur chimérique soluble hyper IL-11 et son utilisation
JP6545105B2 (ja) 2013-02-07 2019-07-17 シーエスエル、リミテッド Il−11r結合タンパク質及びその使用
US10308719B2 (en) * 2015-01-26 2019-06-04 The University Of Chicago IL13Rα2 binding agents and use thereof in cancer treatment
GB201522186D0 (en) 2015-12-16 2016-01-27 Singapore Health Services Pte Ltd And Nat University Of Singapore The Treatment of fibrosis
GB201621439D0 (en) * 2016-12-16 2017-02-01 Singapore Health Services Pte Ltd And Nat Univ Of Singapore IL-11Ra Antibodies

Also Published As

Publication number Publication date
EA202092605A1 (ru) 2021-06-01
TW202016140A (zh) 2020-05-01
CA3101401A1 (fr) 2019-12-19
AU2019286797A1 (en) 2021-01-28
CL2020003218A1 (es) 2021-07-30
JP7437325B2 (ja) 2024-02-22
JP2021527086A (ja) 2021-10-11
CR20210010A (es) 2021-06-01
GB201809700D0 (en) 2018-08-01
CO2020015376A2 (es) 2021-04-19
DOP2020000236A (es) 2021-10-31
PH12020552229A1 (en) 2021-06-28
KR20210031645A (ko) 2021-03-22
CN113226471A (zh) 2021-08-06
JOP20200300A1 (ar) 2020-11-22
PE20211500A1 (es) 2021-08-11
ECSP21001499A (es) 2021-03-31
US20190389957A1 (en) 2019-12-26
US20200377605A9 (en) 2020-12-03
MX2020013468A (es) 2021-04-13
US11084878B2 (en) 2021-08-10
EP3806959A1 (fr) 2021-04-21
SG11202011648UA (en) 2020-12-30
BR112020025502A2 (pt) 2021-03-16
IL279352A (en) 2021-01-31
WO2019238884A1 (fr) 2019-12-19

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