MA46064B1 - Pyridin-2- (1h) -one-quinolinone derivatives as isocitrate dehydrogenase inhibitors - Google Patents
Pyridin-2- (1h) -one-quinolinone derivatives as isocitrate dehydrogenase inhibitorsInfo
- Publication number
- MA46064B1 MA46064B1 MA46064A MA46064A MA46064B1 MA 46064 B1 MA46064 B1 MA 46064B1 MA 46064 A MA46064 A MA 46064A MA 46064 A MA46064 A MA 46064A MA 46064 B1 MA46064 B1 MA 46064B1
- Authority
- MA
- Morocco
- Prior art keywords
- pyridin
- isocitrate dehydrogenase
- dehydrogenase inhibitors
- quinolinone derivatives
- quinolinone
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Cette invention concerne des inhibiteurs de protéines d'isocitrate déshydrogénase mutantes (mt-idh) ayant une activité néomorphe, utiles pour traiter les troubles liés à la prolifération cellulaire et les cancers, de formule : (i) où a, u, w1, w2, w3, r1-r6, et r9 sont tels que décrits dans la présente.This invention relates to mutant isocitrate dehydrogenase (mt-idh) protein inhibitors having neomorphic activity useful for treating cell proliferation-related disorders and cancers of the formula: (i) where a, u, w1, w2 , w3, r1-r6, and r9 are as described herein.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462053006P | 2014-09-19 | 2014-09-19 | |
US201562128089P | 2015-03-04 | 2015-03-04 | |
US201562150812P | 2015-04-21 | 2015-04-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
MA46064A MA46064A (en) | 2019-07-03 |
MA46064B1 true MA46064B1 (en) | 2020-04-30 |
Family
ID=58698665
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA46064A MA46064B1 (en) | 2014-09-19 | 2015-09-18 | Pyridin-2- (1h) -one-quinolinone derivatives as isocitrate dehydrogenase inhibitors |
Country Status (3)
Country | Link |
---|---|
AR (1) | AR101976A1 (en) |
HR (1) | HRP20182176T1 (en) |
MA (1) | MA46064B1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107556366A (en) * | 2016-06-30 | 2018-01-09 | 上海海和药物研究开发有限公司 | Compound, preparation method and the usage with saltant type isocitric dehydrogenase inhibitory activity |
BR112023024454A2 (en) * | 2021-06-15 | 2024-02-06 | Wigen Biomedicine Tech Shanghai Co Ltd | COMPOUND OF GENERAL FORMULA (1) OR AN ISOMER, A CRYSTALLINE FORM, A PHARMACEUTICALLY ACCEPTABLE SALT, A HYDRATE OR A SOLVATE THEREOF; AND; USE OF THE COMPOUND OR ISOMER |
-
2015
- 2015-09-18 AR ARP150103022A patent/AR101976A1/en active IP Right Grant
- 2015-09-18 MA MA46064A patent/MA46064B1/en unknown
-
2018
- 2018-12-21 HR HRP20182176TT patent/HRP20182176T1/en unknown
Also Published As
Publication number | Publication date |
---|---|
MA46064A (en) | 2019-07-03 |
HRP20182176T1 (en) | 2019-02-22 |
AR101976A1 (en) | 2017-01-25 |
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