MA45407A - Compositions et méthodes de déplétion de cellules - Google Patents
Compositions et méthodes de déplétion de cellulesInfo
- Publication number
- MA45407A MA45407A MA045407A MA45407A MA45407A MA 45407 A MA45407 A MA 45407A MA 045407 A MA045407 A MA 045407A MA 45407 A MA45407 A MA 45407A MA 45407 A MA45407 A MA 45407A
- Authority
- MA
- Morocco
- Prior art keywords
- compositions
- methods
- cell deletion
- deletion
- cell
- Prior art date
Links
- 238000012217 deletion Methods 0.000 title 1
- 230000037430 deletion Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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US10961537B2 (en) | 2017-07-18 | 2021-03-30 | Csl Behring Gene Therapy, Inc. | Compositions and methods for treating beta-hemoglobinopathies |
JP2021524449A (ja) * | 2018-05-23 | 2021-09-13 | アーデーセー セラピューティクス ソシエテ アノニム | 分子アジュバント |
CA3107383A1 (fr) * | 2018-07-23 | 2020-01-30 | Magenta Therapeutics, Inc. | Utilisation d'un conjugue anticorps anti-cd5 -medicament (adc) dans une therapie cellulaire allogenique |
CA3107378A1 (fr) * | 2018-07-23 | 2020-01-30 | Magenta Therapeutics, Inc. | Utilisation d'un conjugue medicament anticorps anti-cd2 (adc) dans une therapie cellulaire allogenique |
AU2019374055A1 (en) * | 2018-10-30 | 2021-06-17 | Magenta Therapeutics, Inc. | Methods for allogeneic hematopoietic stem cell transplantation |
CA3117367A1 (fr) * | 2018-10-30 | 2020-05-07 | Magenta Therapeutics, Inc. | Anticorps anti-cd45 et leurs conjugues |
BR112021012240A2 (pt) | 2018-12-23 | 2022-01-18 | Csl Behring Llc | Terapia de gene-célula-tronco hematopoiética para síndrome wiskott-aldrich |
EP3908296A4 (fr) * | 2019-01-07 | 2022-09-14 | Magenta Therapeutics, Inc. | Utilisation d'un conjugué médicament anticorps anti-cd45 (adc) dans une thérapie cellulaire |
EP3958910A4 (fr) * | 2019-04-24 | 2023-08-02 | Magenta Therapeutics, Inc. | Conjugués anticorps anti-cd45-médicaments et leurs utilisations |
AU2020261079A1 (en) * | 2019-04-24 | 2021-12-23 | Magenta Therapeutics, Inc. | Conditioning methods for gene therapy |
WO2020219861A1 (fr) * | 2019-04-25 | 2020-10-29 | Actinium Pharmaceuticals, Inc. | Compositions et procédés d'immunodéplétion pour le traitement des maladies hématologiques malignes et non malignes |
WO2020247670A1 (fr) * | 2019-06-04 | 2020-12-10 | Magenta Therapeutics, Inc. | Procédés et compositions pour le traitement de maladies auto-immunes |
BR112021026376A2 (pt) * | 2019-06-25 | 2022-05-10 | Gilead Sciences Inc | Proteínas de fusão flt3l-fc e métodos de uso |
EP3997128A4 (fr) * | 2019-07-09 | 2023-10-18 | Hemogenyx Pharmaceuticals Llc | Procédé d'élimination de cellules souches hématopoïétique/progéniteurs hématopoïétiques (csh/ph) chez un patient à l'aide d'anticorps bispécifiques |
CA3145697A1 (fr) * | 2019-07-30 | 2021-02-04 | Dendrocyte Biotech Pty Ltd | Immunoconjugue anti-cd300f |
AU2021224663A1 (en) * | 2020-02-18 | 2022-09-08 | Magenta Therapeutics, Inc. | Compositions and methods for allogeneic transplantation |
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2017
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EP3471772A4 (fr) | 2020-03-18 |
SG11201811292RA (en) | 2019-01-30 |
CA3028145A1 (fr) | 2017-12-21 |
AU2017204139A1 (en) | 2018-01-18 |
US20190192682A1 (en) | 2019-06-27 |
KR20230082055A (ko) | 2023-06-08 |
US20190328901A1 (en) | 2019-10-31 |
JP2022163075A (ja) | 2022-10-25 |
WO2017219025A1 (fr) | 2017-12-21 |
AU2018208749B2 (en) | 2020-09-03 |
EP3471772A1 (fr) | 2019-04-24 |
IL263743A (en) | 2019-01-31 |
JP2024037832A (ja) | 2024-03-19 |
AU2020217338A1 (en) | 2020-08-27 |
JP2019522050A (ja) | 2019-08-08 |
BR112018076263A2 (pt) | 2019-03-26 |
US10624973B2 (en) | 2020-04-21 |
KR20190039085A (ko) | 2019-04-10 |
AU2017204139B2 (en) | 2018-08-09 |
AU2018208749A1 (en) | 2018-08-16 |
US20200376134A1 (en) | 2020-12-03 |
CN109641051A (zh) | 2019-04-16 |
MX2018015683A (es) | 2019-05-27 |
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