MA44227A - Anticorps pour il-17c - Google Patents
Anticorps pour il-17cInfo
- Publication number
- MA44227A MA44227A MA044227A MA44227A MA44227A MA 44227 A MA44227 A MA 44227A MA 044227 A MA044227 A MA 044227A MA 44227 A MA44227 A MA 44227A MA 44227 A MA44227 A MA 44227A
- Authority
- MA
- Morocco
- Prior art keywords
- antibodies
- fragments
- relates
- antibody
- psoriasis
- Prior art date
Links
- 102000013691 Interleukin-17 Human genes 0.000 title abstract 2
- 108050003558 Interleukin-17 Proteins 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La présente invention concerne des anticorps ou des fragments d'anticorps se liant à l'il-17c humaine. En particulier, l'invention concerne des anticorps ou des fragments d'anticorps qui présentent des propriétés bénéfiques combinées et sont donc utiles pour le traitement d'êtres humains présentant, par exemple, une dermatite atopique ou un psoriasis.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16156582 | 2016-02-19 | ||
EP16156651 | 2016-02-22 | ||
PCT/EP2017/053592 WO2017140831A1 (fr) | 2016-02-19 | 2017-02-17 | Anticorps anti-il-17c |
Publications (2)
Publication Number | Publication Date |
---|---|
MA44227A true MA44227A (fr) | 2018-12-26 |
MA44227B1 MA44227B1 (fr) | 2021-06-30 |
Family
ID=58057136
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA44227A MA44227B1 (fr) | 2016-02-19 | 2017-02-17 | Anticorps pour il-17c |
MA43088A MA43088B1 (fr) | 2016-02-19 | 2017-02-17 | Anticorps anti-il-17c |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA43088A MA43088B1 (fr) | 2016-02-19 | 2017-02-17 | Anticorps anti-il-17c |
Country Status (32)
Country | Link |
---|---|
US (4) | US20190048071A1 (fr) |
EP (1) | EP3416983B1 (fr) |
JP (2) | JP6535139B2 (fr) |
KR (1) | KR20180109977A (fr) |
CN (1) | CN108699143B (fr) |
AU (1) | AU2017219837B2 (fr) |
BR (1) | BR112018016798A2 (fr) |
CA (1) | CA3014842A1 (fr) |
CL (1) | CL2018002340A1 (fr) |
CO (1) | CO2018008724A2 (fr) |
CU (1) | CU20180087A7 (fr) |
CY (1) | CY1124296T1 (fr) |
DK (1) | DK3416983T3 (fr) |
EA (1) | EA037813B1 (fr) |
EC (1) | ECSP18070641A (fr) |
ES (1) | ES2877376T3 (fr) |
HR (1) | HRP20211059T1 (fr) |
HU (1) | HUE054755T2 (fr) |
IL (1) | IL260733B2 (fr) |
LT (1) | LT3416983T (fr) |
MA (2) | MA44227B1 (fr) |
MD (1) | MD3416983T2 (fr) |
MX (1) | MX2018009860A (fr) |
PH (1) | PH12018501739A1 (fr) |
PL (1) | PL3416983T3 (fr) |
RS (1) | RS62012B1 (fr) |
SG (1) | SG11201806161TA (fr) |
SI (1) | SI3416983T1 (fr) |
TN (1) | TN2018000289A1 (fr) |
TW (1) | TW201734041A (fr) |
WO (1) | WO2017140831A1 (fr) |
ZA (1) | ZA201806249B (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20190048071A1 (en) | 2016-02-19 | 2019-02-14 | Morphosys Ag | Antibodies for il-17c |
TW201919698A (zh) | 2017-09-25 | 2019-06-01 | 德商莫菲西斯公司 | 異位性皮炎之治療 |
GB201803563D0 (en) | 2018-03-06 | 2018-04-18 | Galapagos Nv | Antibodies and pharmaceutical compositions thereof for the treatment of autoimmune skin diseases |
TW202011995A (zh) | 2018-07-03 | 2020-04-01 | 比利時商葛萊伯格有限公司 | 高濃度液體抗體配製物 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4708871A (en) | 1983-03-08 | 1987-11-24 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
ES2301198T3 (es) | 1997-06-12 | 2008-06-16 | Novartis International Pharmaceutical Ltd. | Polipeptidos artificiales de anticuerpos. |
EP2333069A3 (fr) * | 1998-05-15 | 2011-09-14 | Genentech, Inc. | Utilisations therapeutiques de polypeptides homologues de il-17 |
DK1144607T5 (da) | 1999-07-20 | 2009-10-05 | Morphosys Ag | Fremgangsmåde til præsentation af (poly)peptider/proteiner på bakteriofage partikler via disulfidbindinger |
US7771951B2 (en) | 2001-12-03 | 2010-08-10 | Amgen Fremont Inc. | Antibody categorization based on binding characteristics |
EA200700823A1 (ru) | 2004-10-18 | 2008-02-28 | Займодженетикс, Инк., Сша | Растворимый zcytor21, анти-zcytor21 антитела и связывающие партнёры и способы применения при воспалении |
US20070129302A1 (en) * | 2005-10-18 | 2007-06-07 | Zeren Gao | Il-17c antagonists and methods of using the same |
CA2666842A1 (fr) | 2006-10-18 | 2008-04-24 | Zymogenetics, Inc. | Antagonistes de l'il-17c et leurs procedes d'utilisation |
TW201307385A (zh) * | 2010-10-25 | 2013-02-16 | Genentech Inc | 胃腸炎症和銀屑病以及哮喘的治療 |
SG10201509257VA (en) | 2010-11-19 | 2015-12-30 | Morphosys Ag | A collection and methods for its use |
US20140234330A1 (en) | 2011-07-22 | 2014-08-21 | Amgen Inc. | Il-17 receptor a is required for il-17c biology |
ES2669984T3 (es) * | 2011-10-19 | 2018-05-29 | Morphosys Ag | Antagonistas de IL17C para el tratamiento de trastornos inflamatorios |
DK2858670T3 (en) | 2012-06-12 | 2018-10-22 | Orega Biotech | Antagonists of IL-17 isoforms and their applications |
AU2015367684A1 (en) * | 2014-12-15 | 2017-07-06 | Galapagos Nv | Antibodies for IL-17C |
US20190048071A1 (en) | 2016-02-19 | 2019-02-14 | Morphosys Ag | Antibodies for il-17c |
-
2017
- 2017-02-17 US US16/076,401 patent/US20190048071A1/en not_active Abandoned
- 2017-02-17 DK DK17705873.2T patent/DK3416983T3/da active
- 2017-02-17 CN CN201780011965.2A patent/CN108699143B/zh active Active
- 2017-02-17 EP EP17705873.2A patent/EP3416983B1/fr active Active
- 2017-02-17 ES ES17705873T patent/ES2877376T3/es active Active
- 2017-02-17 HU HUE17705873A patent/HUE054755T2/hu unknown
- 2017-02-17 BR BR112018016798A patent/BR112018016798A2/pt unknown
- 2017-02-17 MA MA44227A patent/MA44227B1/fr unknown
- 2017-02-17 MX MX2018009860A patent/MX2018009860A/es unknown
- 2017-02-17 MA MA43088A patent/MA43088B1/fr unknown
- 2017-02-17 TN TNP/2018/000289A patent/TN2018000289A1/en unknown
- 2017-02-17 SG SG11201806161TA patent/SG11201806161TA/en unknown
- 2017-02-17 TW TW106105384A patent/TW201734041A/zh unknown
- 2017-02-17 IL IL260733A patent/IL260733B2/en unknown
- 2017-02-17 MD MDE20190007T patent/MD3416983T2/ro unknown
- 2017-02-17 SI SI201730777T patent/SI3416983T1/sl unknown
- 2017-02-17 WO PCT/EP2017/053592 patent/WO2017140831A1/fr active Application Filing
- 2017-02-17 RS RS20210775A patent/RS62012B1/sr unknown
- 2017-02-17 KR KR1020187024953A patent/KR20180109977A/ko not_active Application Discontinuation
- 2017-02-17 JP JP2018543220A patent/JP6535139B2/ja active Active
- 2017-02-17 CU CU2018000087A patent/CU20180087A7/es unknown
- 2017-02-17 AU AU2017219837A patent/AU2017219837B2/en active Active
- 2017-02-17 LT LTEP17705873.2T patent/LT3416983T/lt unknown
- 2017-02-17 EA EA201891594A patent/EA037813B1/ru unknown
- 2017-02-17 CA CA3014842A patent/CA3014842A1/fr active Pending
- 2017-02-17 PL PL17705873T patent/PL3416983T3/pl unknown
-
2018
- 2018-08-08 US US16/058,143 patent/US10259869B2/en active Active
- 2018-08-16 PH PH12018501739A patent/PH12018501739A1/en unknown
- 2018-08-16 CL CL2018002340A patent/CL2018002340A1/es unknown
- 2018-08-21 CO CONC2018/0008724A patent/CO2018008724A2/es unknown
- 2018-09-17 ZA ZA2018/06249A patent/ZA201806249B/en unknown
- 2018-09-19 EC ECSENADI201870641A patent/ECSP18070641A/es unknown
-
2019
- 2019-02-26 US US16/286,231 patent/US10633439B2/en active Active
- 2019-04-26 JP JP2019086144A patent/JP6916834B2/ja active Active
-
2020
- 2020-03-18 US US16/822,844 patent/US11987621B2/en active Active
-
2021
- 2021-07-02 HR HRP20211059TT patent/HRP20211059T1/hr unknown
- 2021-07-06 CY CY20211100604T patent/CY1124296T1/el unknown
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