MA43987A - Détermination de la pureté de protéine multimère - Google Patents
Détermination de la pureté de protéine multimèreInfo
- Publication number
- MA43987A MA43987A MA043987A MA43987A MA43987A MA 43987 A MA43987 A MA 43987A MA 043987 A MA043987 A MA 043987A MA 43987 A MA43987 A MA 43987A MA 43987 A MA43987 A MA 43987A
- Authority
- MA
- Morocco
- Prior art keywords
- purity
- determination
- multimer protein
- multimer
- protein
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/33—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/061—Sources
- G01N2201/06113—Coherent sources; lasers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
- G01N27/44726—Arrangements for investigating the separated zones, e.g. localising zones by optical means using specific dyes, markers or binding molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44795—Isoelectric focusing
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562160341P | 2015-05-12 | 2015-05-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA43987A true MA43987A (fr) | 2018-12-19 |
Family
ID=56072452
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA043987A MA43987A (fr) | 2015-05-12 | 2016-05-11 | Détermination de la pureté de protéine multimère |
MA056416A MA56416A (fr) | 2015-05-12 | 2016-05-11 | Détermination de la pureté de protéines multimériques |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA056416A MA56416A (fr) | 2015-05-12 | 2016-05-11 | Détermination de la pureté de protéines multimériques |
Country Status (11)
Country | Link |
---|---|
US (2) | US10520511B2 (fr) |
EP (2) | EP3885368A1 (fr) |
JP (3) | JP7240812B2 (fr) |
AR (1) | AR104610A1 (fr) |
AU (2) | AU2016261854B2 (fr) |
CA (1) | CA2984010A1 (fr) |
ES (1) | ES2881359T3 (fr) |
HK (1) | HK1252480A1 (fr) |
MA (2) | MA43987A (fr) |
PL (1) | PL3294775T3 (fr) |
WO (1) | WO2016183222A1 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3384274B1 (fr) | 2015-11-30 | 2021-11-10 | Intabio, Inc. | Procédés de caractérisation d'échantillon |
CN109937034B (zh) | 2016-11-21 | 2022-09-16 | 济世-伊沃泰克生物制品有限公司 | 阿柏西普制剂及其用途 |
EP3668985B1 (fr) | 2017-08-17 | 2021-06-16 | Just-Evotec Biologics, Inc. | Procédé de purification de protéine glycosylée à partir de galectines et d'autres contaminants de cellules hôtes |
JP7333326B2 (ja) | 2018-01-29 | 2023-08-24 | インタバイオ, エルエルシー | 試料の特性評価のための装置、方法およびキット |
WO2019232397A1 (fr) | 2018-05-31 | 2019-12-05 | Intabio, Inc. | Logiciel pour systèmes microfluidiques faisant interface avec la spectrométrie de masse |
MX2021002573A (es) * | 2018-09-10 | 2021-05-12 | Genentech Inc | Sistemas y procedimientos para electroforesis capilar de afinidad. |
US11573226B2 (en) * | 2018-09-10 | 2023-02-07 | Genentech, Inc. | Systems and methods for affinity capillary electrophoresis |
US11782023B2 (en) * | 2018-12-19 | 2023-10-10 | Regeneron Pharmaceuticals, Inc. | Ce-western applications for antibody development |
KR20210122803A (ko) * | 2019-01-31 | 2021-10-12 | 리제너론 파아마슈티컬스, 인크. | 항체 전하 이질성의 고유 마이크로유체 ce-ms 분석 |
US11285484B2 (en) | 2019-08-12 | 2022-03-29 | Intabio, Llc | Multichannel isoelectric focusing devices and high voltage power supplies |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPP385598A0 (en) | 1998-06-02 | 1998-06-25 | Life Therapeutics Limited | Purification of antibodies |
US6472179B2 (en) * | 1998-09-25 | 2002-10-29 | Regeneron Pharmaceuticals, Inc. | Receptor based antagonists and methods of making and using |
EP1194768A4 (fr) * | 1999-04-20 | 2008-03-26 | Target Discovery Inc | Procedes de cartographie peptidique de polypeptides, etablissement de profils et systeme de base de donnees bioinformatique |
US6818112B2 (en) * | 1999-04-20 | 2004-11-16 | Target Discovery, Inc. | Protein separation via multidimensional electrophoresis |
US7087411B2 (en) | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
AUPQ743300A0 (en) * | 2000-05-11 | 2000-06-01 | Life Therapeutics Limited | Separation of avian antibodies |
US6927004B2 (en) | 2002-03-08 | 2005-08-09 | Asml Netherlands B.V. | Mask for use in lithography, method of making a mask, lithographic apparatus, and device manufacturing method |
JPWO2007034907A1 (ja) * | 2005-09-22 | 2009-03-26 | 財団法人化学物質評価研究機構 | 被検化学物質の生物に与える影響の予測方法 |
EP1803814A1 (fr) | 2005-12-27 | 2007-07-04 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Procédé d'amélioration la capacité de sélection d'anticorps dans une bibliothèque d'affichage de phages |
EP4218801A3 (fr) * | 2006-03-31 | 2023-08-23 | Chugai Seiyaku Kabushiki Kaisha | Procédé de modification d'anticorps pour purifier un anticorps bispécifique |
US7771997B2 (en) | 2007-06-04 | 2010-08-10 | Regeneron Pharmaceuticals, Inc. | Enhanced expression and stability regions |
PL2202245T3 (pl) * | 2007-09-26 | 2017-02-28 | Chugai Seiyaku Kabushiki Kaisha | Sposób modyfikowania punktu izoelektrycznego przeciwciała poprzez podstawienie aminokwasu w cdr |
JP4977588B2 (ja) | 2007-12-07 | 2012-07-18 | 富士フイルム株式会社 | イムノクロマトグラフ方法 |
KR20120027055A (ko) | 2009-06-26 | 2012-03-20 | 리제네론 파라마큐티칼스 인코포레이티드 | 천연 면역글로불린 포맷을 가지는 용이하게 분리된 이중특이성 항체 |
SG195073A1 (en) | 2011-05-21 | 2013-12-30 | Macrogenics Inc | Deimmunized serum-binding domains and their use for extending serum half-life |
GB2504139B (en) * | 2012-07-20 | 2014-12-31 | Argen X Bv | Antibodies to highly conserved targets produced by the immunisation of Camelidae species |
EP2604624A1 (fr) * | 2011-12-13 | 2013-06-19 | University College Dublin National University Of Ireland, Dublin | Peptides de liaison de l'inhibiteur de protéase de Bowman-Birk (BBO) et utilisations associées pour la séparation, la détection ou la purification du BBI. |
US9815909B2 (en) * | 2012-03-13 | 2017-11-14 | Novimmune S.A. | Readily isolated bispecific antibodies with native immunoglobulin format |
SG11201407644UA (en) | 2012-06-05 | 2014-12-30 | Regeneron Pharma | Methods for making fully human bispecific antibodies using a common light chain |
TWI675044B (zh) * | 2012-11-14 | 2019-10-21 | 美商再生元醫藥公司 | 重組細胞表面捕捉蛋白質 |
WO2015024896A1 (fr) * | 2013-08-19 | 2015-02-26 | F. Hoffmann-La Roche Ag | Séparation d'anticorps bispécifiques et sous-produits de la production d'anticorps bispécifiques utilisant la chromatographie sur hydroxyapatite |
CA2922979A1 (fr) * | 2013-09-03 | 2015-03-12 | Novimmune S.A. | Molecules de liaison bispecifiques facilement isolees au format natif, mais possedant des regions constantes mutees |
-
2016
- 2016-05-11 US US15/152,135 patent/US10520511B2/en active Active
- 2016-05-11 ES ES16724805T patent/ES2881359T3/es active Active
- 2016-05-11 MA MA043987A patent/MA43987A/fr unknown
- 2016-05-11 CA CA2984010A patent/CA2984010A1/fr active Pending
- 2016-05-11 WO PCT/US2016/031899 patent/WO2016183222A1/fr unknown
- 2016-05-11 JP JP2017558949A patent/JP7240812B2/ja active Active
- 2016-05-11 EP EP21171963.8A patent/EP3885368A1/fr active Pending
- 2016-05-11 AU AU2016261854A patent/AU2016261854B2/en active Active
- 2016-05-11 MA MA056416A patent/MA56416A/fr unknown
- 2016-05-11 EP EP16724805.3A patent/EP3294775B1/fr active Active
- 2016-05-11 PL PL16724805T patent/PL3294775T3/pl unknown
- 2016-05-12 AR ARP160101379A patent/AR104610A1/es unknown
-
2018
- 2018-09-13 HK HK18111788.3A patent/HK1252480A1/zh unknown
-
2019
- 2019-11-18 US US16/686,770 patent/US20200166522A1/en active Pending
-
2021
- 2021-06-02 JP JP2021092988A patent/JP7137663B2/ja active Active
-
2022
- 2022-05-05 AU AU2022203033A patent/AU2022203033A1/en active Pending
- 2022-09-02 JP JP2022139802A patent/JP2022171730A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP7240812B2 (ja) | 2023-03-16 |
AU2022203033A1 (en) | 2022-05-26 |
HK1252480A1 (zh) | 2019-05-24 |
EP3294775A1 (fr) | 2018-03-21 |
US20170045527A1 (en) | 2017-02-16 |
US10520511B2 (en) | 2019-12-31 |
JP2022171730A (ja) | 2022-11-11 |
US20200166522A1 (en) | 2020-05-28 |
WO2016183222A1 (fr) | 2016-11-17 |
EP3885368A1 (fr) | 2021-09-29 |
AU2016261854A1 (en) | 2017-11-09 |
WO2016183222A4 (fr) | 2017-01-05 |
JP2018528389A (ja) | 2018-09-27 |
MA56416A (fr) | 2022-05-04 |
ES2881359T3 (es) | 2021-11-29 |
JP2021152544A (ja) | 2021-09-30 |
AU2016261854B2 (en) | 2022-05-26 |
EP3294775B1 (fr) | 2021-07-14 |
JP7137663B2 (ja) | 2022-09-14 |
PL3294775T3 (pl) | 2021-12-13 |
CA2984010A1 (fr) | 2016-11-17 |
AR104610A1 (es) | 2017-08-02 |
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