MA40894A - HETERODIMERIC IMMUNOGLOBULINS RE-TARGET CD3 / CD38 T-LYMPHOCYTES AND THEIR PRODUCTION PROCESSES - Google Patents

HETERODIMERIC IMMUNOGLOBULINS RE-TARGET CD3 / CD38 T-LYMPHOCYTES AND THEIR PRODUCTION PROCESSES

Info

Publication number: MA40894A
Authority: MA; Morocco
Prior art keywords: lymphocytes; target; production processes; heterodimeric immunoglobulins; heterodimeric
Prior art date: 2014-11-04

Application number

MA040894A

Other languages

French (fr)

Inventor

Jonathan Back

Samuel Hou

Rami Lissilaa

Romain Ollier

Darko Skegro

Original Assignee

Glenmark Pharmaceuticals Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-11-04

Filing date

2015-11-02

Publication date

2017-09-12

2014-11-04 Priority claimed from PCT/EP2014/073738 external-priority patent/WO2015063339A1/en

2015-11-02 Application filed by Glenmark Pharmaceuticals Sa filed Critical Glenmark Pharmaceuticals Sa

2017-09-12 Publication of MA40894A publication Critical patent/MA40894A/en

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

MA040894A 2014-11-04 2015-11-02 HETERODIMERIC IMMUNOGLOBULINS RE-TARGET CD3 / CD38 T-LYMPHOCYTES AND THEIR PRODUCTION PROCESSES MA40894A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
PCT/EP2014/073738 WO2015063339A1 (en)	2013-11-04	2014-11-04	Production of t cell retargeting hetero-dimeric immunoglobulins
EP15167034		2015-05-08

Publications (1)

Publication Number	Publication Date
MA40894A true MA40894A (en)	2017-09-12

Family

ID=53059011

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA040894A MA40894A (en)	2014-11-04	2015-11-02	HETERODIMERIC IMMUNOGLOBULINS RE-TARGET CD3 / CD38 T-LYMPHOCYTES AND THEIR PRODUCTION PROCESSES

Country Status (20)

Country	Link
EP (1)	EP3215541A1 (en)
JP (3)	JP2018501297A (en)
KR (1)	KR20170078831A (en)
CN (1)	CN107207596A (en)
AU (1)	AU2015341884B2 (en)
BR (1)	BR112017009263A2 (en)
CA (1)	CA2965745C (en)
CL (1)	CL2017001090A1 (en)
CO (1)	CO2017005240A2 (en)
EA (1)	EA039658B1 (en)
HK (1)	HK1244014A1 (en)
IL (1)	IL251848A0 (en)
MA (1)	MA40894A (en)
MX (1)	MX2017005814A (en)
MY (1)	MY186929A (en)
NZ (1)	NZ732019A (en)
PE (1)	PE20171041A1 (en)
PH (1)	PH12017500819A1 (en)
SG (1)	SG11201703313SA (en)
WO (1)	WO2016071355A1 (en)

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WO2015013671A1 (en)	2013-07-25	2015-01-29	Cytomx Therapeutics, Inc.	Multispecific antibodies, multispecific activatable antibodies and methods of using the same
EP3176185A1 (en)	2013-11-04	2017-06-07	Glenmark Pharmaceuticals S.A.	Production of t cell retargeting hetero-dimeric immunoglobulins
KR102497443B1 (en)	2014-03-28	2023-02-08	젠코어 인코포레이티드	Bispecific antibodies that bind to cd38 and cd3
BR112017001579A2 (en) *	2014-07-25	2017-11-21	Cytomx Therapeutics Inc	anti-cd3 antibodies, activatable anti-cd3 antibodies, multispecific anti-cd3 antibodies, multispecific activatable cd3 antibodies and methods of use
US11773166B2 (en)	2014-11-04	2023-10-03	Ichnos Sciences SA	CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production
PE20171103A1 (en)	2014-11-26	2017-08-07	Xencor Inc	HETERODIMERIC ANTIBODIES THAT BIND TO CD3 AND CD38
CA2967426A1 (en)	2014-11-26	2016-06-02	Xencor, Inc.	Heterodimeric antibodies that bind cd3 and tumor antigens
US10259887B2 (en)	2014-11-26	2019-04-16	Xencor, Inc.	Heterodimeric antibodies that bind CD3 and tumor antigens
TWI829617B (en)	2015-07-31	2024-01-21	德商安美基研究（慕尼黑）公司	Antibody constructs for flt3 and cd3
TWI796283B (en)	2015-07-31	2023-03-21	德商安美基研究（慕尼黑）公司	Antibody constructs for msln and cd3
CN108699136B (en)	2015-12-07	2022-03-18	Xencor股份有限公司	Heterodimeric antibodies that bind CD3 and PSMA
EA039859B1 (en)	2016-02-03	2022-03-21	Эмджен Рисерч (Мюник) Гмбх	Bispecific antibody constructs binding egfrviii and cd3
RU2022104399A (en)	2016-06-14	2022-05-05	Ксенкор, Инк.	BISPECIFIC ANTIBODIES-CHECKPOINT INHIBITORS
CA3060190A1 (en) *	2017-04-24	2018-11-01	Glenmark Pharmaceuticals S.A.	T cell redirecting bispecific antibodies for the treatment of egfr positive cancers
WO2018224441A1 (en) *	2017-06-05	2018-12-13	Numab Innovation Ag	Novel anti-cd3 antibodies
CN110691789A (en)	2017-06-05	2020-01-14	努玛治疗有限公司	Novel anti-CD 3 antibodies
CN111051344B (en)	2017-06-08	2023-10-27	黑带医疗有限公司	CD38 modulating antibodies
CA3066555A1 (en) *	2017-06-08	2018-12-13	Black Belt Therapeutics Limited	Cd38 modulating antibody
UY37757A (en)	2017-08-10	2018-11-30	Grifols Diagnostic Solutions Inc	COMPOSITIONS, PROCEDURES AND / OR KITS THAT INCLUDE AN EXTRACELLULAR DOMAIN OF RECOMBINANT HUMAN CD38
CA3072296A1 (en)	2017-08-16	2019-02-21	Black Belt Therapeutics Limited	Cd38 antibody
WO2019035938A1 (en)	2017-08-16	2019-02-21	Elstar Therapeutics, Inc.	Multispecific molecules that bind to bcma and uses thereof
US11542338B2 (en)	2017-08-16	2023-01-03	Black Belt Therapeutics Limited	CD38 modulating antibody
US11472889B2 (en)	2017-10-14	2022-10-18	Cytomx Therapeutics, Inc.	Antibodies, activatable antibodies, bispecific antibodies, and bispecific activatable antibodies and methods of use thereof
WO2020064865A1 (en) *	2018-09-25	2020-04-02	Ichnos Sciences S.A.	Antibody quantification in biological samples
KR102353568B1 (en) *	2018-11-14	2022-01-20	주식회사 헬릭스미스	Anti c-Met Antibody or Antigen binding fragment thereof with Improved Stability
BR112021014574A2 (en) *	2019-01-23	2021-10-05	Encefa	CD31 COMPETITORS AND USES THEREOF
US20220177582A1 (en) *	2019-03-13	2022-06-09	Ichnos Sciences SA	Non-consensus glycosylation of bispecific antibodies
CN113874399A (en) *	2019-05-23	2021-12-31	维洛斯生物股份有限公司	anti-ROR 1/anti-CD 3 bispecific binding molecules
EP3984554A4 (en) *	2019-06-11	2023-11-08	ONO Pharmaceutical Co., Ltd.	Immunosuppression agent
CN110551222B (en) *	2019-08-27	2023-06-06	重庆市畜牧科学院	Novel bifunctional antibody and application thereof
CN113015749B (en) *	2019-09-30	2022-01-21	和铂医药(苏州)有限公司	Antibodies targeting CD3, bispecific antibodies, and uses thereof
CN113493519B (en) *	2020-03-19	2022-12-27	浙江道尔生物科技有限公司	Fusion protein with remarkably prolonged half-life for treating ocular angiogenesis diseases
US11919956B2 (en)	2020-05-14	2024-03-05	Xencor, Inc.	Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
US20230312742A1 (en) *	2020-06-17	2023-10-05	Y-Mabs Therapeutics, Inc.	CD38 antibodies for the treatment of human diseases
KR102607909B1 (en)	2020-08-19	2023-12-01	젠코어 인코포레이티드	Anti-CD28 composition
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EP1720907B1 (en) *	2004-02-06	2015-04-08	MorphoSys AG	Anti-cd38 human antibodies and uses therefor
SG10201912554TA (en) *	2005-03-23	2020-02-27	Genmab As	Antibodies against cd38 for treatment of multiple myeloma
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EP1914242A1 (en) *	2006-10-19	2008-04-23	Sanofi-Aventis	Novel anti-CD38 antibodies for the treatment of cancer
PL2975051T3 (en) *	2009-06-26	2021-09-20	Regeneron Pharmaceuticals, Inc.	Readily isolated bispecific antibodies with native immunoglobulin format
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EA201791693A1 (en) *	2011-03-25	2018-05-31	Гленмарк Фармасьютикалс С.А.	HETERODIMERNY IMMUNOHLOBULINS
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DK2914302T3 (en) *	2012-11-05	2017-04-10	Morphosys Ag	RADIOACTIVALLY MARKED ANTIBODY AND USES OF IT
EP3176185A1 (en) *	2013-11-04	2017-06-07	Glenmark Pharmaceuticals S.A.	Production of t cell retargeting hetero-dimeric immunoglobulins

2015
- 2015-11-02 MA MA040894A patent/MA40894A/en unknown
- 2015-11-03 EP EP15790129.9A patent/EP3215541A1/en not_active Withdrawn
- 2015-11-03 JP JP2017542319A patent/JP2018501297A/en active Pending
- 2015-11-03 WO PCT/EP2015/075628 patent/WO2016071355A1/en active Application Filing
- 2015-11-03 PE PE2017000802A patent/PE20171041A1/en unknown
- 2015-11-03 MX MX2017005814A patent/MX2017005814A/en unknown
- 2015-11-03 AU AU2015341884A patent/AU2015341884B2/en active Active
- 2015-11-03 EA EA201790961A patent/EA039658B1/en unknown
- 2015-11-03 SG SG11201703313SA patent/SG11201703313SA/en unknown
- 2015-11-03 KR KR1020177015252A patent/KR20170078831A/en not_active Application Discontinuation
- 2015-11-03 CN CN201580072196.8A patent/CN107207596A/en active Pending
- 2015-11-03 BR BR112017009263-8A patent/BR112017009263A2/en active Search and Examination
- 2015-11-03 CA CA2965745A patent/CA2965745C/en active Active
- 2015-11-03 MY MYPI2017701499A patent/MY186929A/en unknown
- 2015-11-03 NZ NZ732019A patent/NZ732019A/en unknown
2017
- 2017-04-23 IL IL251848A patent/IL251848A0/en unknown
- 2017-05-02 CL CL2017001090A patent/CL2017001090A1/en unknown
- 2017-05-03 PH PH12017500819A patent/PH12017500819A1/en unknown
- 2017-05-26 CO CONC2017/0005240A patent/CO2017005240A2/en unknown
2018
- 2018-03-12 HK HK18103440.0A patent/HK1244014A1/en unknown
2019
- 2019-07-23 JP JP2019135318A patent/JP2019214582A/en active Pending
2021
- 2021-08-02 JP JP2021126392A patent/JP7403505B2/en active Active

Also Published As

Publication number	Publication date
JP2019214582A (en)	2019-12-19
CN107207596A (en)	2017-09-26
AU2015341884B2 (en)	2020-09-17
JP2021184722A (en)	2021-12-09
EA201790961A1 (en)	2017-10-31
CA2965745C (en)	2023-12-05
WO2016071355A1 (en)	2016-05-12
CA2965745A1 (en)	2016-05-12
CL2017001090A1 (en)	2018-01-05
AU2015341884A1 (en)	2017-06-08
BR112017009263A2 (en)	2018-01-30
JP2018501297A (en)	2018-01-18
KR20170078831A (en)	2017-07-07
HK1244014A1 (en)	2018-07-27
MX2017005814A (en)	2017-08-02
EP3215541A1 (en)	2017-09-13
CO2017005240A2 (en)	2017-10-31
NZ732019A (en)	2022-07-29
PE20171041A1 (en)	2017-07-19
EA039658B1 (en)	2022-02-22
MY186929A (en)	2021-08-26
JP7403505B2 (en)	2023-12-22
PH12017500819A1 (en)	2017-10-02
IL251848A0 (en)	2017-06-29
SG11201703313SA (en)	2017-05-30

Publication	Publication Date	Title
MA40894A (en)	2017-09-12	HETERODIMERIC IMMUNOGLOBULINS RE-TARGET CD3 / CD38 T-LYMPHOCYTES AND THEIR PRODUCTION PROCESSES
HK1245171A1 (en)	2018-08-24	Heterodimeric antibodies that bind cd3 and cd38
HK1257164A1 (en)	2019-10-18	Novel anti-pd-l1 antibodies
IL255727A (en)	2018-01-31	Novel anti-pd-l1 antibodies
HK1246324A1 (en)	2018-09-07	Anti-pd-l1 antibodies
IL248007A0 (en)	2016-11-30	Bispecific antibodies that bind to cd38 and cd3
MA43389A (en)	2021-05-12	ANTI-OX40 ANTIBODIES AND PROCESSES FOR USE
MA40889A (en)	2017-09-12	HEREODIMERIC IMMUNOGLOBULINS RE-TARGET LYMPHOCYTES
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HK1251055A1 (en)	2019-01-18	Automated interpretation for the layout of structured multi-field files
PL3223845T3 (en)	2021-11-22	Heterodimeric antibodies that bind cd3 and cd20
MA42829A (en)	2021-04-14	COMPOSITIONS DERIVED FROM PLACENTA AND PROCESSES FOR PRODUCING THEM
MA41375A (en)	2017-11-28	BISPECIFIC IGG ANTIBODIES AND THEIR PREPARATION PROCESSES
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MA44517A (en)	2019-02-06	RECOMBINANT INTRAVENOUS IMMUNOGLOBULIN (RIVIG) COMPOSITIONS AND PROCESSES FOR PRODUCTION AND USE
DK3250491T3 (en)	2022-06-13	Product turner and placer
ZA201604024B (en)	2017-08-30	Improved feeding strategies and purification processes for monoclonal antibody production
GB201621446D0 (en)	2017-02-01	IL-11 antibodies
TH176441B (en)	2018-06-07	Production systems and production methods for nitrogen-containing products And products that were selected from fermented / cultured products
TH1501005423A (en)	2018-06-21	Adhesion molecule for BCMA and CD3
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