MA40403A - Méthodes de traitement de paramyxovirus - Google Patents
Méthodes de traitement de paramyxovirusInfo
- Publication number
- MA40403A MA40403A MA040403A MA40403A MA40403A MA 40403 A MA40403 A MA 40403A MA 040403 A MA040403 A MA 040403A MA 40403 A MA40403 A MA 40403A MA 40403 A MA40403 A MA 40403A
- Authority
- MA
- Morocco
- Prior art keywords
- treating
- methods
- paramyxoviruses
- methylpropanoate
- cytidine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
La présente invention concerne des procédés pour l'amélioration et/ou le traitement d'une infection à paramyxovirus, ou l'inhibition de la réplication d'un paramyxovirus, par l'utilisation de 3',5'-(2-méthylpropanoate-4'-c-(chlorométhyl)-2'-désoxy-2'-fluoro-cytidine (composé a)), le composé (a) ou son sel pharmaceutiquement acceptable pouvant fournir 4'-c-chlorométhyl-2'-désoxy-2'-fluoro-5'- (tétrahydrogène triphosphate)-cytidine ou son sel pharmaceutiquement acceptable (composé (b)).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462027719P | 2014-07-22 | 2014-07-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA40403A true MA40403A (fr) | 2017-05-31 |
Family
ID=55163588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA040403A MA40403A (fr) | 2014-07-22 | 2015-07-20 | Méthodes de traitement de paramyxovirus |
Country Status (13)
Country | Link |
---|---|
US (1) | US20160022724A1 (fr) |
EP (1) | EP3171878A4 (fr) |
JP (1) | JP2017525681A (fr) |
KR (1) | KR20170031231A (fr) |
AU (1) | AU2015294343A1 (fr) |
BR (1) | BR112017001162A2 (fr) |
CA (1) | CA2955604A1 (fr) |
CL (1) | CL2017000156A1 (fr) |
MA (1) | MA40403A (fr) |
MX (1) | MX2017000983A (fr) |
RU (1) | RU2017105470A (fr) |
TW (1) | TW201609104A (fr) |
WO (1) | WO2016014398A1 (fr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LT2794627T (lt) | 2011-12-22 | 2019-01-10 | Alios Biopharma, Inc. | Pakeistieji nukleozidai, nukleotidai ir jų analogai |
AU2012358804B2 (en) | 2011-12-22 | 2018-04-19 | Alios Biopharma, Inc. | Substituted phosphorothioate nucleotide analogs |
US8916538B2 (en) | 2012-03-21 | 2014-12-23 | Vertex Pharmaceuticals Incorporated | Solid forms of a thiophosphoramidate nucleotide prodrug |
US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
USRE48171E1 (en) | 2012-03-21 | 2020-08-25 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
CA2894541A1 (fr) | 2012-12-21 | 2014-06-26 | Alios Biopharma, Inc. | Nucleosides, nucleotides substitues et leurs analogues |
KR102168621B1 (ko) | 2012-12-21 | 2020-10-22 | 얀센 바이오파마, 인코퍼레이트. | 치환된 뉴클레오사이드, 뉴클레오타이드 및 그것의 유사체 |
CA2908313A1 (fr) | 2013-04-05 | 2014-10-09 | Alios Biopharma, Inc. | Traitement contre une infection par le virus de l'hepatite c utilisant une combinaison de composes |
US9815864B2 (en) | 2013-06-26 | 2017-11-14 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
ES2825035T3 (es) | 2013-06-26 | 2021-05-14 | Janssen Biopharma Inc | Nucleósidos, nucleótidos y análogos de estos sustituidos con 4-azidoalquilo |
AU2014331863C1 (en) | 2013-10-11 | 2019-05-16 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
CA2952959C (fr) | 2014-06-24 | 2023-03-07 | Alios Biopharma, Inc. | Utilisation de nucleosides et de nucleotides pour traiter une infection de filovirus |
EP3797782A1 (fr) | 2014-06-24 | 2021-03-31 | Janssen BioPharma, Inc. | Nucléosides substitués, nucléotides et leurs analogues pour traiter les infections virales |
CN106999509A (zh) * | 2014-08-05 | 2017-08-01 | 艾丽奥斯生物制药有限公司 | 用于治疗副粘病毒的联合治疗 |
CN107108681B (zh) | 2014-10-28 | 2021-04-06 | 詹森生物制药有限公司 | 制备取代的核苷类似物的方法 |
MA41213A (fr) | 2014-12-19 | 2017-10-24 | Alios Biopharma Inc | Nucléosides substitués, nucléotides et analogues de ceux-ci |
MA41441A (fr) | 2014-12-19 | 2017-12-12 | Alios Biopharma Inc | Nucléosides substitués, nucléotides et analogues de ceux-ci |
WO2016145103A1 (fr) | 2015-03-11 | 2016-09-15 | Alios Biopharma, Inc. | Composés d'aza-pyridone et leurs utilisations |
WO2018081449A1 (fr) * | 2016-10-27 | 2018-05-03 | Alios Biopharma, Inc. | Méthode pour le traitement d'une infection par le virus respiratoire syncytial |
WO2018222774A1 (fr) * | 2017-05-30 | 2018-12-06 | Alios Biopharma, Inc. | Méthodes de traitement des pneumovirus |
CN113462656B (zh) * | 2021-03-24 | 2022-09-30 | 兰州生物制品研究所有限责任公司 | 一种人三型副流感病毒冷适应温度敏感株及其应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2115927C (fr) * | 1991-08-26 | 2009-04-21 | Francis V. Chisari | Peptides pour l'induction de reponses des lymphocytes t cytotoxiques contre le virus de l'hepatite b |
JPH0859508A (ja) * | 1994-08-16 | 1996-03-05 | Teijin Ltd | サイトメガロウイルス網膜炎予防または治療剤 |
PE20130395A1 (es) * | 2010-06-24 | 2013-04-10 | Gilead Sciences Inc | Pirazolo[1,5-a]pirimidinas para tratamiento antiviral |
LT2794627T (lt) * | 2011-12-22 | 2019-01-10 | Alios Biopharma, Inc. | Pakeistieji nukleozidai, nukleotidai ir jų analogai |
PL2827875T3 (pl) * | 2012-03-21 | 2019-07-31 | Janssen Biopharma, Inc. | Podstawione nukleozydy, nukleotydy i ich analogi |
-
2015
- 2015-07-20 US US14/804,034 patent/US20160022724A1/en not_active Abandoned
- 2015-07-20 KR KR1020177004409A patent/KR20170031231A/ko unknown
- 2015-07-20 AU AU2015294343A patent/AU2015294343A1/en not_active Abandoned
- 2015-07-20 RU RU2017105470A patent/RU2017105470A/ru not_active Application Discontinuation
- 2015-07-20 EP EP15825198.3A patent/EP3171878A4/fr not_active Withdrawn
- 2015-07-20 WO PCT/US2015/041111 patent/WO2016014398A1/fr active Application Filing
- 2015-07-20 MX MX2017000983A patent/MX2017000983A/es unknown
- 2015-07-20 CA CA2955604A patent/CA2955604A1/fr not_active Abandoned
- 2015-07-20 MA MA040403A patent/MA40403A/fr unknown
- 2015-07-20 JP JP2017503609A patent/JP2017525681A/ja active Pending
- 2015-07-20 BR BR112017001162A patent/BR112017001162A2/pt not_active IP Right Cessation
- 2015-07-22 TW TW104123747A patent/TW201609104A/zh unknown
-
2017
- 2017-01-20 CL CL2017000156A patent/CL2017000156A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
MX2017000983A (es) | 2017-09-01 |
KR20170031231A (ko) | 2017-03-20 |
CA2955604A1 (fr) | 2016-01-28 |
WO2016014398A1 (fr) | 2016-01-28 |
RU2017105470A3 (fr) | 2019-02-28 |
EP3171878A4 (fr) | 2018-03-14 |
TW201609104A (zh) | 2016-03-16 |
CL2017000156A1 (es) | 2017-11-03 |
US20160022724A1 (en) | 2016-01-28 |
AU2015294343A1 (en) | 2017-02-02 |
RU2017105470A (ru) | 2018-08-22 |
BR112017001162A2 (pt) | 2017-11-14 |
EP3171878A1 (fr) | 2017-05-31 |
JP2017525681A (ja) | 2017-09-07 |
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