MA39141A1 - Humanized anti-tau antibodies (ps422) and methods of use thereof - Google Patents

Humanized anti-tau antibodies (ps422) and methods of use thereof

Info

Publication number
MA39141A1
MA39141A1 MA39141A MA39141A MA39141A1 MA 39141 A1 MA39141 A1 MA 39141A1 MA 39141 A MA39141 A MA 39141A MA 39141 A MA39141 A MA 39141A MA 39141 A1 MA39141 A1 MA 39141A1
Authority
MA
Morocco
Prior art keywords
methods
humanized anti
tau antibodies
tau
antibodies
Prior art date
Application number
MA39141A
Other languages
French (fr)
Inventor
Hubert Kettenberger
Guy Georges
Michael Schraeml
Bernd Bohrmann
Joerg Benz
Ulrich Goepfert
Fiona Grueninger
Olaf Mundigl
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority claimed from PCT/EP2014/078234 external-priority patent/WO2015091656A1/en
Publication of MA39141A1 publication Critical patent/MA39141A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne des anticorps anti-tau(ps422) humain humanisés et des méthodes d'utilisation de ceux-ci.The present invention provides humanized human anti-tau (ps422) antibodies and methods of use thereof.

MA39141A 2013-12-20 2014-12-17 Humanized anti-tau antibodies (ps422) and methods of use thereof MA39141A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13199123 2013-12-20
PCT/EP2014/078234 WO2015091656A1 (en) 2013-12-20 2014-12-17 HUMANIZED ANTI-Tau(pS422) ANTIBODIES AND METHODS OF USE

Publications (1)

Publication Number Publication Date
MA39141A1 true MA39141A1 (en) 2017-06-30

Family

ID=49876465

Family Applications (1)

Application Number Title Priority Date Filing Date
MA39141A MA39141A1 (en) 2013-12-20 2014-12-17 Humanized anti-tau antibodies (ps422) and methods of use thereof

Country Status (2)

Country Link
AR (1) AR098855A1 (en)
MA (1) MA39141A1 (en)

Also Published As

Publication number Publication date
AR098855A1 (en) 2016-06-15

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