MA35158B1 - Formulations topiques de type suspension comprenant un depsipeptide cyclique - Google Patents
Formulations topiques de type suspension comprenant un depsipeptide cycliqueInfo
- Publication number
- MA35158B1 MA35158B1 MA36445A MA36445A MA35158B1 MA 35158 B1 MA35158 B1 MA 35158B1 MA 36445 A MA36445 A MA 36445A MA 36445 A MA36445 A MA 36445A MA 35158 B1 MA35158 B1 MA 35158B1
- Authority
- MA
- Morocco
- Prior art keywords
- cyclic depsipeptide
- suspension formulations
- topical suspension
- relates
- topical
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention porte sur de nouvelles compositions pharmaceutiques topiques dans lesquelles le principe actif est un depsipeptide cyclique de formule (ii) et sur des procédés pour la fabrication de telles compositions. L'invention porte en particulier sur des onguents hydrophobes comprenant une base hydrophobe et un agent modifiant la consistance, de préférence du myristate d'isopropyle.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161477297P | 2011-04-20 | 2011-04-20 | |
PCT/IB2012/051946 WO2012143868A1 (fr) | 2011-04-20 | 2012-04-18 | Formulations topiques de type suspension comprenant un depsipeptide cyclique |
Publications (1)
Publication Number | Publication Date |
---|---|
MA35158B1 true MA35158B1 (fr) | 2014-06-02 |
Family
ID=46148908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA36445A MA35158B1 (fr) | 2011-04-20 | 2013-11-15 | Formulations topiques de type suspension comprenant un depsipeptide cyclique |
Country Status (21)
Country | Link |
---|---|
US (2) | US8680054B2 (fr) |
EP (1) | EP2699231B1 (fr) |
JP (1) | JP5906304B2 (fr) |
KR (1) | KR101612170B1 (fr) |
CN (1) | CN103476396B (fr) |
AR (1) | AR086109A1 (fr) |
AU (1) | AU2012245960B2 (fr) |
BR (1) | BR112013026698A2 (fr) |
CA (1) | CA2833326A1 (fr) |
CL (1) | CL2013003036A1 (fr) |
EA (1) | EA201391555A1 (fr) |
ES (1) | ES2651639T3 (fr) |
GT (1) | GT201300257A (fr) |
IL (1) | IL228863A0 (fr) |
MA (1) | MA35158B1 (fr) |
MX (1) | MX338156B (fr) |
PE (1) | PE20141068A1 (fr) |
SG (1) | SG11201402441WA (fr) |
TN (1) | TN2013000386A1 (fr) |
TW (1) | TW201247218A (fr) |
WO (1) | WO2012143868A1 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY151973A (en) | 2007-08-17 | 2014-07-31 | Novartis Ag | Cyclic depsipeptides |
US8680054B2 (en) | 2011-04-20 | 2014-03-25 | Novartis Ag | Suspension type topical formulations comprising cyclic depsipeptide |
US8614289B2 (en) | 2011-04-20 | 2013-12-24 | Novartis Ag | Processes for the manufacture of macrocyclic depsipeptides and new intermediates |
US8987413B2 (en) | 2012-10-09 | 2015-03-24 | Novartis Ag | Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates |
US9067978B2 (en) | 2012-10-09 | 2015-06-30 | Novartis Ag | Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates |
US9226890B1 (en) | 2013-12-10 | 2016-01-05 | Englewood Lab, Llc | Polysilicone base for scar treatment |
CN108888590A (zh) * | 2018-08-06 | 2018-11-27 | 江苏知原药业有限公司 | 包含他克莫司的混悬类型的局部制剂 |
JP2023516754A (ja) * | 2020-03-06 | 2023-04-20 | ライフマックス ラボラトリーズ インコーポレイテッド | 環状デプシペプチドの局所医薬製剤 |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3043252C2 (de) | 1980-11-15 | 1982-12-02 | Degussa Ag, 6000 Frankfurt | Cyclische Acetale von N-Acylglutaminsäure -γ- semialdehyden, Verfahren zu deren Herstellung und ihre Verwendung |
US5595756A (en) | 1993-12-22 | 1997-01-21 | Inex Pharmaceuticals Corporation | Liposomal compositions for enhanced retention of bioactive agents |
DE4421113A1 (de) | 1994-06-16 | 1995-12-21 | Biotechnolog Forschung Gmbh | Chondramide, Gewinnungsverfahren, Mittel mit Chondramiden und Mischkultur zur Chondramid-Gewinnung |
DE19828043A1 (de) | 1998-06-24 | 1999-12-30 | Bayer Ag | Ektoparasitizide Mittel |
JP2000154198A (ja) | 1998-11-20 | 2000-06-06 | Nisshin Flour Milling Co Ltd | 環状デプシペプチドの固相合成方法及びその中間体 |
JP2001131085A (ja) * | 1999-08-25 | 2001-05-15 | Saitama Daiichi Seiyaku Kk | 経皮・経粘膜吸収用の医薬組成物 |
GB0108234D0 (en) | 2001-04-02 | 2001-05-23 | Pharma Mar Sa | Process for producing trunkamide A compounds |
US20040110228A1 (en) | 2002-04-01 | 2004-06-10 | Mcalpine Shelli R. | Combinatorial organic synthesis of unique biologically active compounds |
KR101099409B1 (ko) | 2003-06-06 | 2011-12-27 | 아렉시스 악티에볼라그 | 피부 상태 또는 암 치료를 위한 scce 저해제로서의융합된 헤테로사이클 화합물의 용도 |
GB0322140D0 (en) * | 2003-09-22 | 2003-10-22 | Pfizer Ltd | Combinations |
DE10358525A1 (de) * | 2003-12-13 | 2005-07-07 | Bayer Healthcare Ag | Endoparasitizide Mittel zur topischen Applikation |
WO2005075667A1 (fr) | 2004-02-03 | 2005-08-18 | Bayer Healthcare Ag | Methodes de diagnostic et de traitement de maladies associees a la kallikreine 7 (klk7) |
JP2009532664A (ja) | 2006-02-27 | 2009-09-10 | アリゾナ・ボード・オブ・リージェンツ・フォー・アンド・オン・ビハーフ・オブ・アリゾナ・ステイト・ユニバーシティ | 癌の治療のためのノボペプチドの同定および使用 |
MY151973A (en) | 2007-08-17 | 2014-07-31 | Novartis Ag | Cyclic depsipeptides |
EP2183270B1 (fr) | 2007-08-17 | 2014-12-17 | Novartis AG | Utilisation de dépsipeptides cycliques pour inhiber la kallikréine 7 |
DE102007052391A1 (de) | 2007-10-31 | 2009-05-07 | Henkel Ag & Co. Kgaa | Mattwachs |
JP2010241784A (ja) * | 2008-06-19 | 2010-10-28 | Mitsubishi Tanabe Pharma Corp | 経皮投与製剤 |
US20110112121A1 (en) | 2009-07-06 | 2011-05-12 | Joerg Berghausen | Pharmaceutical Compositions and Solid Forms |
KR101004362B1 (ko) | 2010-03-19 | 2010-12-28 | 가톨릭대학교 산학협력단 | 자가 면역 질환 예방 및 치료용 TNF-α와 TWEAK 이중 길항제 |
US20120064136A1 (en) | 2010-09-10 | 2012-03-15 | Nanobio Corporation | Anti-aging and wrinkle treatment methods using nanoemulsion compositions |
WO2012035468A2 (fr) | 2010-09-14 | 2012-03-22 | Trima - Israel Pharmaceutical Products Maabarot Ltd. | Composition topique moussante |
WO2012103035A1 (fr) | 2011-01-24 | 2012-08-02 | Anterios, Inc. | Compositions de nanoparticules |
US20120328701A1 (en) | 2011-01-24 | 2012-12-27 | Anterios, Inc. | Nanoparticle compositions, formulations thereof, and uses therefor |
US8614289B2 (en) | 2011-04-20 | 2013-12-24 | Novartis Ag | Processes for the manufacture of macrocyclic depsipeptides and new intermediates |
US8680054B2 (en) | 2011-04-20 | 2014-03-25 | Novartis Ag | Suspension type topical formulations comprising cyclic depsipeptide |
US9067978B2 (en) | 2012-10-09 | 2015-06-30 | Novartis Ag | Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates |
US8987413B2 (en) | 2012-10-09 | 2015-03-24 | Novartis Ag | Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates |
-
2012
- 2012-04-12 US US13/445,202 patent/US8680054B2/en active Active
- 2012-04-18 WO PCT/IB2012/051946 patent/WO2012143868A1/fr active Application Filing
- 2012-04-18 EP EP12723241.1A patent/EP2699231B1/fr active Active
- 2012-04-18 EA EA201391555A patent/EA201391555A1/ru unknown
- 2012-04-18 BR BR112013026698A patent/BR112013026698A2/pt not_active IP Right Cessation
- 2012-04-18 JP JP2014505768A patent/JP5906304B2/ja active Active
- 2012-04-18 PE PE2013002371A patent/PE20141068A1/es not_active Application Discontinuation
- 2012-04-18 AR ARP120101325 patent/AR086109A1/es unknown
- 2012-04-18 CN CN201280018749.8A patent/CN103476396B/zh active Active
- 2012-04-18 KR KR1020137027256A patent/KR101612170B1/ko not_active IP Right Cessation
- 2012-04-18 CA CA 2833326 patent/CA2833326A1/fr not_active Abandoned
- 2012-04-18 SG SG11201402441WA patent/SG11201402441WA/en unknown
- 2012-04-18 ES ES12723241.1T patent/ES2651639T3/es active Active
- 2012-04-18 AU AU2012245960A patent/AU2012245960B2/en not_active Ceased
- 2012-04-18 MX MX2013012187A patent/MX338156B/es active IP Right Grant
- 2012-04-19 TW TW101114020A patent/TW201247218A/zh unknown
-
2013
- 2013-09-25 TN TNP2013000386A patent/TN2013000386A1/fr unknown
- 2013-10-14 IL IL228863A patent/IL228863A0/en unknown
- 2013-10-18 CL CL2013003036A patent/CL2013003036A1/es unknown
- 2013-10-18 GT GT201300257A patent/GT201300257A/es unknown
- 2013-11-15 MA MA36445A patent/MA35158B1/fr unknown
-
2014
- 2014-02-04 US US14/171,807 patent/US9114110B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
KR20130133295A (ko) | 2013-12-06 |
US8680054B2 (en) | 2014-03-25 |
JP2014512377A (ja) | 2014-05-22 |
AU2012245960B2 (en) | 2014-09-25 |
IL228863A0 (en) | 2013-12-31 |
AU2012245960A1 (en) | 2013-10-17 |
US20140162959A1 (en) | 2014-06-12 |
KR101612170B1 (ko) | 2016-04-12 |
EA201391555A1 (ru) | 2014-11-28 |
AR086109A1 (es) | 2013-11-20 |
CN103476396A (zh) | 2013-12-25 |
NZ615551A (en) | 2015-08-28 |
EP2699231B1 (fr) | 2017-09-13 |
TN2013000386A1 (en) | 2015-01-20 |
CL2013003036A1 (es) | 2014-04-04 |
ES2651639T3 (es) | 2018-01-29 |
MX2013012187A (es) | 2013-11-04 |
US9114110B2 (en) | 2015-08-25 |
PE20141068A1 (es) | 2014-09-04 |
CN103476396B (zh) | 2015-08-05 |
US20120270796A1 (en) | 2012-10-25 |
TW201247218A (en) | 2012-12-01 |
MX338156B (es) | 2016-04-05 |
JP5906304B2 (ja) | 2016-04-20 |
WO2012143868A1 (fr) | 2012-10-26 |
GT201300257A (es) | 2015-02-19 |
CA2833326A1 (fr) | 2012-10-26 |
BR112013026698A2 (pt) | 2016-12-27 |
SG11201402441WA (en) | 2014-09-26 |
EP2699231A1 (fr) | 2014-02-26 |
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