MA32560B1 - Nouveaux derives tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents
Nouveaux derives tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennentInfo
- Publication number
- MA32560B1 MA32560B1 MA33612A MA33612A MA32560B1 MA 32560 B1 MA32560 B1 MA 32560B1 MA 33612 A MA33612 A MA 33612A MA 33612 A MA33612 A MA 33612A MA 32560 B1 MA32560 B1 MA 32560B1
- Authority
- MA
- Morocco
- Prior art keywords
- contain
- pharmaceutical compositions
- preparation process
- tricyclic derivatives
- new tricyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Composés de formule (i) dans laquelle : a représente un cycle (hétéro)aromatique ou non contenant 5, 6 ou 7 chaînons; z1, z2 et z3 représentent indépendamment les uns des autres un groupement ch ou un atome d'azote, sachant qu'au moins un de ces trois groupes est un atome d'azote; x représente une chaîne alkylène telle que définie dans la description; r2 représente un groupement aryle ou hétéroaryle, le groupements r1 représente un groupement de formule (ii) tel que défini dans la description.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0804014A FR2933983B1 (fr) | 2008-07-15 | 2008-07-15 | Nouveaux derives tricycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
PCT/FR2009/000855 WO2010007248A2 (fr) | 2008-07-15 | 2009-07-10 | Nouveaux derives tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
MA32560B1 true MA32560B1 (fr) | 2011-08-01 |
Family
ID=40404284
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA33612A MA32560B1 (fr) | 2008-07-15 | 2011-02-11 | Nouveaux derives tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Country Status (14)
Country | Link |
---|---|
US (1) | US20110112104A1 (fr) |
EP (1) | EP2303880A2 (fr) |
JP (1) | JP2011528028A (fr) |
KR (1) | KR20110030686A (fr) |
CN (1) | CN102149714A (fr) |
AR (1) | AR072745A1 (fr) |
AU (1) | AU2009272612A1 (fr) |
BR (1) | BRPI0916775A2 (fr) |
CA (1) | CA2730516A1 (fr) |
EA (1) | EA201100188A1 (fr) |
FR (1) | FR2933983B1 (fr) |
MA (1) | MA32560B1 (fr) |
MX (1) | MX2011000533A (fr) |
WO (1) | WO2010007248A2 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6426745B2 (ja) * | 2013-10-04 | 2018-11-21 | ウニヴェルズィテート バーゼル | 配座固定されたPI3K及びmTOR阻害剤 |
SG11202001262QA (en) * | 2017-08-15 | 2020-03-30 | Agios Pharmaceuticals Inc | Pyruvate kinase activators for use in treating blood disorders |
WO2020094084A1 (fr) * | 2018-11-07 | 2020-05-14 | 南京明德新药研发有限公司 | Dérivé tricyclique utilisé comme inhibiteur de ret |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5688950A (en) * | 1996-04-23 | 1997-11-18 | Neurogen Corporation | Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands |
AU2006239236A1 (en) * | 2005-04-28 | 2006-11-02 | Supergen, Inc. | Protein kinase inhibitors |
FR2912145B1 (fr) * | 2007-02-02 | 2009-03-06 | Servier Lab | Nouveaux derives tricycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2008
- 2008-07-15 FR FR0804014A patent/FR2933983B1/fr not_active Expired - Fee Related
-
2009
- 2009-07-10 US US12/737,436 patent/US20110112104A1/en not_active Abandoned
- 2009-07-10 CN CN2009801356769A patent/CN102149714A/zh active Pending
- 2009-07-10 WO PCT/FR2009/000855 patent/WO2010007248A2/fr active Application Filing
- 2009-07-10 BR BRPI0916775-7A patent/BRPI0916775A2/pt not_active IP Right Cessation
- 2009-07-10 EA EA201100188A patent/EA201100188A1/ru unknown
- 2009-07-10 JP JP2011517964A patent/JP2011528028A/ja not_active Withdrawn
- 2009-07-10 KR KR1020117003376A patent/KR20110030686A/ko not_active Application Discontinuation
- 2009-07-10 EP EP09784263A patent/EP2303880A2/fr not_active Withdrawn
- 2009-07-10 MX MX2011000533A patent/MX2011000533A/es not_active Application Discontinuation
- 2009-07-10 CA CA2730516A patent/CA2730516A1/fr not_active Abandoned
- 2009-07-10 AU AU2009272612A patent/AU2009272612A1/en not_active Abandoned
- 2009-07-14 AR ARP090102653A patent/AR072745A1/es unknown
-
2011
- 2011-02-11 MA MA33612A patent/MA32560B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
AU2009272612A1 (en) | 2010-01-21 |
FR2933983A1 (fr) | 2010-01-22 |
WO2010007248A3 (fr) | 2010-04-08 |
WO2010007248A2 (fr) | 2010-01-21 |
CN102149714A (zh) | 2011-08-10 |
FR2933983B1 (fr) | 2010-08-27 |
EP2303880A2 (fr) | 2011-04-06 |
EA201100188A1 (ru) | 2011-08-30 |
AR072745A1 (es) | 2010-09-15 |
CA2730516A1 (fr) | 2010-01-21 |
KR20110030686A (ko) | 2011-03-23 |
US20110112104A1 (en) | 2011-05-12 |
MX2011000533A (es) | 2011-02-22 |
BRPI0916775A2 (pt) | 2018-02-14 |
JP2011528028A (ja) | 2011-11-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA200701176A1 (ru) | Новые соединения нафталина, способ их получения и фармацевтические композиции, содержащие их | |
MY144633A (en) | New tricyclic derivatives, method of preparing same and pharmaceutical compositions containing them | |
MY160942A (en) | Melanin production inhibitor | |
RS51661B (en) | NEW DIOSMETHINE DERIVATIVES, THE PROCEDURE FOR THEIR MAKING AND THE PHARMACEUTICAL MIXTURES CONTAINING THEM | |
TW200720249A (en) | Pyrrolidine compound | |
WO2008081096A3 (fr) | Derives quinolinyliques, leur procede de preparation. les compositions pharmaceutiques qui les contiennent et leur utilisation comme agents hypoglycemiants et hypoli pemiants | |
TW200612920A (en) | Novel imidazolidine derivatives | |
TN2010000061A1 (en) | Tricyclic bridged cyclopentanedione derivatives as herbicides | |
ATE482221T1 (de) | Bisamid-zinkbasen | |
EA201001087A1 (ru) | Новые дигидроиндолоновые соединения, способ их получения и фармацевтические композиции, содержащие их | |
EA200501530A1 (ru) | Новые соединения бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат | |
MY164789A (en) | Heterocyclic compounds for treating or preventing disorders caused by reduced neurotransmission of serotonin, norephnephrine or dopamine | |
MA32560B1 (fr) | Nouveaux derives tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent | |
GB2470170A (en) | Dithienothiophene derivatives | |
WO2009035024A1 (fr) | Dérivé de fullerène | |
SG165381A1 (en) | Novel benzimidazole and benzothiazole derivatives, method for preparing same, use thereof as drugs, pharmaceutical compositions and novel use in particular as c-met inhibitors | |
EA200900481A1 (ru) | Новые соединения индола, способ их получения и фармацевтические композиции, которые их содержат | |
SG168482A1 (en) | New chromene compounds, a process for their preparation and pharmaceutical compositions containing them | |
MX2012005596A (es) | Derivados de difenil azepano como inhibidores de reabsorcion de monoaminas. | |
WO2009063785A1 (fr) | Dérivé de fullerène et convertisseur photoélectrique organique l'utilisant | |
WO2008059068A3 (fr) | Titanocène substitué par un carbonyle | |
UA83638C2 (ru) | Соединения 4-оксо-4,6,7,8-тетрагидропирроло[1,2-a]пиразин-6-карбоксамида, способ их получения и фармацевтическая композиция, которая их содержит | |
EA200601248A1 (ru) | Новые многократно замещённые соединения 1,1-пиридилоксициклопропанамина, способ их получения и фармацевтические композиции, которые их содержат | |
SG158015A1 (en) | New azabicyclic compounds, a process for their preparation and pharmaceutical compositions containing them | |
ATE523502T1 (de) | Zearalenon-makrolidderivate und ihre verwendung |