MA23621A1 - Heteroaryl oxazolidinones a 5 membres - Google Patents

Heteroaryl oxazolidinones a 5 membres

Info

Publication number
MA23621A1
MA23621A1 MA23960A MA23960A MA23621A1 MA 23621 A1 MA23621 A1 MA 23621A1 MA 23960 A MA23960 A MA 23960A MA 23960 A MA23960 A MA 23960A MA 23621 A1 MA23621 A1 MA 23621A1
Authority
MA
Morocco
Prior art keywords
members
oxazolidinones
heteroaryl
heteroaryl oxazolidinones
Prior art date
Application number
MA23960A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MA23621A1 publication Critical patent/MA23621A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/08Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
MA23960A 1994-07-20 1995-07-19 Heteroaryl oxazolidinones a 5 membres MA23621A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4425613A DE4425613A1 (de) 1994-07-20 1994-07-20 5-gliedrige Heteroaryl-oxazolidinone

Publications (1)

Publication Number Publication Date
MA23621A1 true MA23621A1 (fr) 1996-04-01

Family

ID=6523633

Family Applications (1)

Application Number Title Priority Date Filing Date
MA23960A MA23621A1 (fr) 1994-07-20 1995-07-19 Heteroaryl oxazolidinones a 5 membres

Country Status (28)

Country Link
US (1) US5698574A (fr)
EP (1) EP0693491A1 (fr)
JP (1) JPH0853443A (fr)
KR (1) KR960004343A (fr)
CN (1) CN1121919A (fr)
AU (1) AU695661B2 (fr)
BG (1) BG99791A (fr)
CA (1) CA2154026A1 (fr)
CO (1) CO4410193A1 (fr)
CZ (1) CZ187395A3 (fr)
DE (1) DE4425613A1 (fr)
EE (1) EE9500044A (fr)
FI (1) FI953476A (fr)
HR (1) HRP950391A2 (fr)
HU (1) HUT74003A (fr)
IL (1) IL114622A (fr)
MA (1) MA23621A1 (fr)
NO (1) NO304488B1 (fr)
NZ (1) NZ272596A (fr)
PE (1) PE35896A1 (fr)
PL (1) PL309685A1 (fr)
RO (1) RO115161B1 (fr)
RU (1) RU95113086A (fr)
SK (1) SK91695A3 (fr)
SV (1) SV1995000042A (fr)
TN (1) TNSN95083A1 (fr)
YU (1) YU49195A (fr)
ZA (1) ZA956015B (fr)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
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DE4425609A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
DE69615002T2 (de) * 1995-02-03 2002-06-13 Pharmacia & Upjohn Co., Kalamazoo Durch hetero-aromatische ring substituierte phenyloxazolidinone als antimikrobielles mittel
US6124334A (en) * 1995-02-03 2000-09-26 Pharmacia & Upjohn Company Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials
SK283487B6 (sk) * 1995-09-01 2003-08-05 Pharmacia And Upjohn Company Fenyloxazolidinóny majúce C-C väzbu v 4 až 8 členných heterocyklických kruhoch
DE19601264A1 (de) * 1996-01-16 1997-07-17 Bayer Ag Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
HRP970049A2 (en) * 1996-02-06 1998-04-30 Bayer Ag New heteroaryl oxazolidinones
DE19604223A1 (de) * 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
ATE227277T1 (de) * 1996-08-21 2002-11-15 Upjohn Co Isoxazoline derivate und ihre verwendung als antimikroben
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) * 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
BR9907183A (pt) 1998-01-23 2003-06-10 Versicor Inc Colet neas combinatórias de oxazolidinona, composições e processos de preparação
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6262044B1 (en) * 1998-03-12 2001-07-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (PTPASES)
US6232322B1 (en) 1998-05-12 2001-05-15 American Home Products Corporation Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6221902B1 (en) 1998-05-12 2001-04-24 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6451827B2 (en) 1998-05-12 2002-09-17 Wyeth 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
US6251936B1 (en) 1998-05-12 2001-06-26 American Home Products Corporation Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
US6121271A (en) * 1998-05-12 2000-09-19 American Home Products Corporation Naphtho[2,3-B]heteroar-4-yl derivatives
US6110963A (en) * 1998-05-12 2000-08-29 American Home Products Corporation Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6214877B1 (en) 1998-05-12 2001-04-10 John A. Butera 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
US6699896B1 (en) 1998-05-12 2004-03-02 Wyeth Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6110962A (en) * 1998-05-12 2000-08-29 American Home Products Corporation 11-aryl-benzo[B]naphtho[2,3-D]furans and 11-aryl-benzo[B]naphtho[2,3-D]thiophenes useful in the treatment of insulin resistance and hyperglycemia
AU756337B2 (en) * 1998-05-12 2003-01-09 Wyeth Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
AU753988B2 (en) 1998-06-05 2002-10-31 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
MY122454A (en) 1998-06-05 2006-04-29 Upjohn Co Use of oxazolidinones for the preparation of a medicament for transdermal delivery
CN1305374A (zh) * 1998-07-14 2001-07-25 法玛西雅厄普约翰美国公司 治疗眼部感染的噁唑烷酮
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
AR020660A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Composiciones antibioticas para el tratamiento de ojos, oidos y nariz
JP2002535680A (ja) 1999-01-27 2002-10-22 ファルマシア・アンド・アップジョン・カンパニー 延長因子p活性モジュレーターのアッセイ方法
US6310081B1 (en) 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
MY127336A (en) * 2000-03-22 2006-11-30 Upjohn Co Container for linezolid iv solution
US6514529B2 (en) 2000-03-22 2003-02-04 Pharmacia & Upjohn Company Oxazolidinone tablet formulation
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
DK1301207T3 (da) 2000-06-30 2005-10-10 Pharmacia & Upjohn Co Llc Sammensætninger til behandling af bakterieinfektioner indeholdende en oxazolidinonforbindelse, sulbactam og ampicillin
PE20020300A1 (es) * 2000-08-22 2002-05-10 Pharmacia Corp Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco
WO2002018354A1 (fr) * 2000-08-31 2002-03-07 Abbott Laboratories Oxazolidinones et leur utilisation en tant qu'agents antibacteriens
PE20020578A1 (es) 2000-10-10 2002-08-14 Upjohn Co Una composicion de antibiotico topico para el tratamiento de infecciones oculares
ATE319710T1 (de) 2000-12-21 2006-03-15 Pharmacia & Upjohn Co Llc Antimikrobielle chinolonderivate und ihre verwendung zur behandlung bakterieller infektionen
GB0118407D0 (en) * 2001-07-27 2001-09-19 Cipla Ltd Oxazolidinone derivatives as antibacterial agents
JP2003192773A (ja) * 2001-12-26 2003-07-09 Mitsui Chemicals Inc 生体吸収性ポリヒドロキシカルボン酸及びその製造法
TW200302095A (en) * 2002-01-25 2003-08-01 Upjohn Co Oxazolidinone cotherapy
BR0307898A (pt) * 2002-02-22 2004-12-07 Pharmacia Corp Formulações de droga antibiótica oftálmica contendo um composto de ciclodextrina e cloreto de cetil piridìnio
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
JP2005527575A (ja) * 2002-03-29 2005-09-15 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 糖尿病性足病変感染を治療するためのオキサゾリジノンの非経口、静脈内および経口投与
WO2004014897A1 (fr) * 2002-08-12 2004-02-19 Pharmacia & Upjohn Company Llc N-aryl-2-oxazolidinones et leurs derives
AR042086A1 (es) * 2002-11-21 2005-06-08 Upjohn Co N-aril-2- oxazolidinon -5- carboxamidas y sus derivados, usados como agentes antibacterianos
CA2507468A1 (fr) * 2002-11-28 2004-06-10 Astrazeneca Ab Derives d'oxazolidinone et/ou d'isoxazoline utilises comme agents antibacteriens
GB0229526D0 (en) * 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
US20040170686A1 (en) * 2003-01-31 2004-09-02 Fredrickson Jennifer K. Suspension vehicle for coated drug particles
JP2006516991A (ja) * 2003-02-07 2006-07-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗菌剤
EP1594494A1 (fr) * 2003-02-07 2005-11-16 Warner-Lambert Company LLC Derives d'oxazolidinone n-substitues par un noyau bicyclique, utilises comme agents antibacteriens
US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
US20040204463A1 (en) * 2003-04-01 2004-10-14 Harris Christina Renee N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
EP1660488A1 (fr) * 2003-08-25 2006-05-31 Warner-Lambert Company LLC Nouveaux composes d'aryloxazolidinone antimicrobiens
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
TW200815428A (en) * 2006-08-15 2008-04-01 Wyeth Corp Oxazolidone derivatives as PR modulators
US7538107B2 (en) * 2006-08-15 2009-05-26 Wyeth Oxazinan-2-one derivatives useful as PR modulators
US7618989B2 (en) * 2006-08-15 2009-11-17 Wyeth Tricyclic oxazolidone derivatives useful as PR modulators
WO2008112495A1 (fr) * 2007-03-09 2008-09-18 Wyeth Synthèse et caractérisation d'une forme polymorphe iii de 4-(2-(4,4-diméthyl-2-oxooxazolidin-3-yl)thiazol-4-yl)benzonitrile
CN104364240B (zh) * 2012-06-08 2017-02-22 四川贝力克生物技术有限责任公司 一种用于预防或治疗分支杆菌疾病的药物

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JPS5735589A (en) * 1980-08-11 1982-02-26 Nippon Soda Co Ltd 5-thienyloxazoline derivative, its preparation and selective herbicide
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ATE146783T1 (de) * 1991-11-01 1997-01-15 Upjohn Co Substituierte aryl- und heteroaryl- phenyloxazolidinone

Also Published As

Publication number Publication date
AU695661B2 (en) 1998-08-20
NZ272596A (en) 1997-03-24
FI953476A0 (fi) 1995-07-18
IL114622A0 (en) 1995-11-27
EP0693491A1 (fr) 1996-01-24
NO304488B1 (no) 1998-12-28
SV1995000042A (es) 1996-03-28
JPH0853443A (ja) 1996-02-27
HU9502167D0 (en) 1995-09-28
SK91695A3 (en) 1996-02-07
KR960004343A (ko) 1996-02-23
FI953476A (fi) 1996-01-21
RO115161B1 (ro) 1999-11-30
CA2154026A1 (fr) 1996-01-21
NO952866L (no) 1996-01-22
AU2498895A (en) 1996-02-01
IL114622A (en) 1999-07-14
YU49195A (sh) 1998-12-23
RU95113086A (ru) 1997-06-27
HRP950391A2 (en) 1997-06-30
TNSN95083A1 (fr) 1996-02-06
BG99791A (en) 1996-04-30
CN1121919A (zh) 1996-05-08
CO4410193A1 (es) 1997-01-09
DE4425613A1 (de) 1996-01-25
ZA956015B (en) 1996-02-22
NO952866D0 (no) 1995-07-19
PE35896A1 (es) 1996-10-14
EE9500044A (et) 1996-02-15
HUT74003A (en) 1996-10-28
US5698574A (en) 1997-12-16
PL309685A1 (en) 1996-01-22
CZ187395A3 (en) 1996-02-14

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