MA22889A1 - Procede de preparation de produits nouveaux - Google Patents
Procede de preparation de produits nouveauxInfo
- Publication number
- MA22889A1 MA22889A1 MA23182A MA23182A MA22889A1 MA 22889 A1 MA22889 A1 MA 22889A1 MA 23182 A MA23182 A MA 23182A MA 23182 A MA23182 A MA 23182A MA 22889 A1 MA22889 A1 MA 22889A1
- Authority
- MA
- Morocco
- Prior art keywords
- preparation
- new products
- products
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929209628A GB9209628D0 (en) | 1992-05-05 | 1992-05-05 | Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MA22889A1 true MA22889A1 (fr) | 1993-12-31 |
Family
ID=10714988
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA23182A MA22889A1 (fr) | 1992-05-05 | 1993-05-03 | Procede de preparation de produits nouveaux |
Country Status (10)
Country | Link |
---|---|
US (1) | US5447954A (fr) |
EP (1) | EP0639187A1 (fr) |
JP (1) | JPH08500085A (fr) |
CN (1) | CN1092418A (fr) |
AU (1) | AU4041293A (fr) |
GB (1) | GB9209628D0 (fr) |
IL (1) | IL105586A0 (fr) |
MA (1) | MA22889A1 (fr) |
SI (1) | SI9300238A (fr) |
WO (1) | WO1993022304A1 (fr) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE303144T1 (de) * | 1995-11-17 | 2005-09-15 | Univ Johns Hopkins | Hemmung der fettsäuresynthase als mittel zur verminderung der adipozytenmenge |
DE19705718A1 (de) * | 1997-02-14 | 1998-08-20 | Horst P O Dr Wolf | Neue Oxirancarbonsäuren zur Behandlung des Diabetes Typ 2 und anderer insulinresistenter Zustände |
US6395767B2 (en) | 2000-03-10 | 2002-05-28 | Bristol-Myers Squibb Company | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method |
JP4598917B2 (ja) * | 2000-04-28 | 2010-12-15 | ダイセル化学工業株式会社 | ラクトンの製造方法 |
EP1332139B1 (fr) | 2000-10-23 | 2007-04-04 | Arizona Biomedical Research Commission | Agents anticancereux dont l'action repose sur la regulation de la prenylation de proteines |
WO2003002732A1 (fr) * | 2001-06-27 | 2003-01-09 | Biovitrum Ab | Polypeptides de citrate lyase |
AU2002348276A1 (en) * | 2001-11-16 | 2003-06-10 | Bristol-Myers Squibb Company | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein |
EP1504525A2 (fr) * | 2002-05-14 | 2005-02-09 | Siemens Aktiengesellschaft | Procede pour generer un signal d'emission |
KR100983990B1 (ko) * | 2002-05-28 | 2010-09-30 | 아지노모토 가부시키가이샤 | Atp 시트르산 리아제의 발현 억제용 의약 조성물 |
EP1626711A4 (fr) * | 2003-05-09 | 2010-10-06 | Univ Pennsylvania | Compositions et methodes de traitement anticancereux |
DE20312620U1 (de) * | 2003-08-14 | 2003-10-09 | Bsh Bosch Siemens Hausgeraete | Kältegerät mit Türsicherung |
US7371759B2 (en) * | 2003-09-25 | 2008-05-13 | Bristol-Myers Squibb Company | HMG-CoA reductase inhibitors and method |
KR100918322B1 (ko) * | 2003-11-12 | 2009-09-22 | 페노믹스 코포레이션 | 헤테로시클릭 보론산 화합물 |
US7767828B2 (en) * | 2003-11-12 | 2010-08-03 | Phenomix Corporation | Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
US7576121B2 (en) * | 2003-11-12 | 2009-08-18 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
US7317109B2 (en) * | 2003-11-12 | 2008-01-08 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
US7420059B2 (en) * | 2003-11-20 | 2008-09-02 | Bristol-Myers Squibb Company | HMG-CoA reductase inhibitors and method |
US7253283B2 (en) | 2004-01-16 | 2007-08-07 | Bristol-Myers Squibb Company | Tricyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof |
EP1778220A1 (fr) * | 2004-07-12 | 2007-05-02 | Phenomix Corporation | Composes cyano contraints |
US7572805B2 (en) | 2004-07-14 | 2009-08-11 | Bristol-Myers Squibb Company | Pyrrolo(oxo)isoquinolines as 5HT ligands |
US7517991B2 (en) * | 2004-10-12 | 2009-04-14 | Bristol-Myers Squibb Company | N-sulfonylpiperidine cannabinoid receptor 1 antagonists |
WO2006076597A1 (fr) * | 2005-01-12 | 2006-07-20 | Bristol-Myers Squibb Company | Heterocycles bicycliques constituant des modulateurs des recepteurs cannabinoides |
US7314882B2 (en) * | 2005-01-12 | 2008-01-01 | Bristol-Myers Squibb Company | Bicyclic heterocycles as cannabinoid receptor modulators |
WO2006076568A2 (fr) | 2005-01-12 | 2006-07-20 | Bristol-Myers Squibb Company | Heterocycles bicycliques servant de modulateurs au recepteur de cannabinoides |
US7317024B2 (en) | 2005-01-13 | 2008-01-08 | Bristol-Myers Squibb Co. | Heterocyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof |
US20060160850A1 (en) * | 2005-01-18 | 2006-07-20 | Chongqing Sun | Bicyclic heterocycles as cannabinoid receptor modulators |
ES2319461T3 (es) * | 2005-02-10 | 2009-05-07 | Bristol-Myers Squibb Company | Dihidroquinazolinonas como moduladores de 5ht. |
US7825139B2 (en) * | 2005-05-25 | 2010-11-02 | Forest Laboratories Holdings Limited (BM) | Compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
US7888381B2 (en) | 2005-06-14 | 2011-02-15 | Bristol-Myers Squibb Company | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity, and use thereof |
US7452892B2 (en) * | 2005-06-17 | 2008-11-18 | Bristol-Myers Squibb Company | Triazolopyrimidine cannabinoid receptor 1 antagonists |
US7629342B2 (en) * | 2005-06-17 | 2009-12-08 | Bristol-Myers Squibb Company | Azabicyclic heterocycles as cannabinoid receptor modulators |
US20060287342A1 (en) * | 2005-06-17 | 2006-12-21 | Mikkilineni Amarendra B | Triazolopyrimidine heterocycles as cannabinoid receptor modulators |
US7317012B2 (en) * | 2005-06-17 | 2008-01-08 | Bristol-Myers Squibb Company | Bicyclic heterocycles as cannabinoind-1 receptor modulators |
US7572808B2 (en) * | 2005-06-17 | 2009-08-11 | Bristol-Myers Squibb Company | Triazolopyridine cannabinoid receptor 1 antagonists |
US7632837B2 (en) * | 2005-06-17 | 2009-12-15 | Bristol-Myers Squibb Company | Bicyclic heterocycles as cannabinoid-1 receptor modulators |
CA2617102A1 (fr) * | 2005-07-28 | 2007-02-08 | Bristol-Myers Squibb Company | Tetrahydro-1h-pyrido[4,3,b]indoles substitues utilises en tant qu'agonistes et antagonistes des recepteurs de la serotonine |
US7795436B2 (en) * | 2005-08-24 | 2010-09-14 | Bristol-Myers Squibb Company | Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists |
US8618115B2 (en) * | 2005-10-26 | 2013-12-31 | Bristol-Myers Squibb Company | Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them |
US7592461B2 (en) | 2005-12-21 | 2009-09-22 | Bristol-Myers Squibb Company | Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof |
US7553836B2 (en) * | 2006-02-06 | 2009-06-30 | Bristol-Myers Squibb Company | Melanin concentrating hormone receptor-1 antagonists |
US20070238770A1 (en) * | 2006-04-05 | 2007-10-11 | Bristol-Myers Squibb Company | Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations |
US7795291B2 (en) | 2006-07-07 | 2010-09-14 | Bristol-Myers Squibb Company | Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method |
WO2008057856A2 (fr) | 2006-11-01 | 2008-05-15 | Bristol-Myers Squibb Company | MODULATEURS DU RÉCEPTEUR DES GLUCOCORTICOÏDES ET DE L'ACTIVITÉ DE AP-1 ET / OU DE NF-ϰB ET UTILISATION DESDITS MODULATEURS |
EP2089389A2 (fr) | 2006-11-01 | 2009-08-19 | Bristol-Myers Squibb Company | Modulateur du récepteur de glucocorticoïdes, ap-1, et/ou activité de nf-kb et leur utilisation |
JP2010508358A (ja) | 2006-11-01 | 2010-03-18 | ブリストル−マイヤーズ スクイブ カンパニー | グルココルチコイド受容体、AP−1、および/またはNF−κB活性の調節剤、並びにその使用 |
EP2089355A2 (fr) | 2006-11-01 | 2009-08-19 | Brystol-Myers Squibb Company | Modulateurs de recepteur de glucocorticoide, d'activite ap-1 et/ou nf- kappa b, et leur utilisation |
EP2581081A3 (fr) | 2007-06-01 | 2013-07-31 | The Trustees Of Princeton University | Traitement d'infections virales par modulation de voies métaboliques de cellules hôtes |
US20090011994A1 (en) * | 2007-07-06 | 2009-01-08 | Bristol-Myers Squibb Company | Non-basic melanin concentrating hormone receptor-1 antagonists and methods |
ES2448839T3 (es) | 2007-11-01 | 2014-03-17 | Bristol-Myers Squibb Company | Compuestos no esteroideos útiles como moderadores de la actividad del receptor de glucocorticoides AP-1 y/o NF-kappa b y uso de los mismos |
PE20091928A1 (es) * | 2008-05-29 | 2009-12-31 | Bristol Myers Squibb Co | Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos |
WO2010104818A1 (fr) | 2009-03-09 | 2010-09-16 | Bristol-Myers Squibb Company | Analogues d'azapyridone utiles comme antagonistes du récepteur 1 de l'hormone concentrant la mélanine |
WO2010104830A1 (fr) | 2009-03-09 | 2010-09-16 | Bristol-Myers Squibb Company | Analogues de pyridone utiles comme antagonistes du récepteur 1 de l'hormone concentrant la mélanine |
CA2756786A1 (fr) | 2009-03-27 | 2010-09-30 | Bristol-Myers Squibb Company | Procedes destines a prevenir des evenements cardiovasculaires indesirables majeurs par des inhibiteurs de la dpp-iv |
US9346852B2 (en) | 2011-03-14 | 2016-05-24 | Bristol-Myers Scuibb Company | Substituted adipic acid amides and uses thereof |
US8815909B2 (en) | 2011-07-18 | 2014-08-26 | Bristol-Myers Squibb Company | Diaminocyclohexane compounds and uses thereof |
US8710049B2 (en) | 2011-07-18 | 2014-04-29 | Bristol-Myers Squibb Company | Diaminocyclohexane compounds and uses thereof |
EP2892897A1 (fr) | 2012-09-05 | 2015-07-15 | Bristol-Myers Squibb Company | Antagonistes du récepteur 1 d'hormone concentrant la mélanine de type pyrrolone ou pyrrolidinone |
WO2014039411A1 (fr) | 2012-09-05 | 2014-03-13 | Bristol-Myers Squibb Company | Antagonistes du récepteur 1 de l'hormone de concentration de pyrrolone ou pyrrolidinone mélanine |
WO2015027021A1 (fr) | 2013-08-22 | 2015-02-26 | Bristol-Myers Squibb Company | Dérivés imide et acylurée utilisés comme modulateurs du récepteur de glucocorticoïdes |
WO2015049365A2 (fr) | 2013-10-03 | 2015-04-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Méthodes et compositions pharmaceutiques permettant la modulation de l'autophagie chez un sujet ayant besoin d'un tel traitement |
WO2016207867A1 (fr) | 2015-02-25 | 2016-12-29 | Université Du Luxembourg | Nat8l et n-acétylaspartate dans le cancer |
JP2021517589A (ja) | 2018-03-12 | 2021-07-26 | アンセルム(アンスティチュート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシェルシュ・メディカル) | 癌の治療のための化学免疫療法を増強するためのカロリー制限模倣物の使用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE478147C (de) * | 1926-03-19 | 1929-06-19 | Hermann Wintzer Metallgiessere | Vorrichtung zum Antrieb von Schmierkolbenpumpen |
US3248187A (en) * | 1961-12-22 | 1966-04-26 | Exxon Research Engineering Co | Alkenyl dicarboxylic acid lactones, their method of preparation and utility |
GB1037985A (en) * | 1963-02-19 | 1966-08-03 | Cheuron Res Company | Alkylbutyrolactone-ª-acetic acids |
DE3813806A1 (de) * | 1988-04-23 | 1989-11-02 | Basf Ag | 11-hydroxy-(gamma)-dodecalacton und seine herstellung |
JP2796884B2 (ja) * | 1990-08-30 | 1998-09-10 | 高砂香料工業株式会社 | 光学活性γ―ブチロラクトン誘導体の製造方法 |
-
1992
- 1992-05-05 GB GB929209628A patent/GB9209628D0/en active Pending
- 1992-05-05 US US08/331,613 patent/US5447954A/en not_active Expired - Fee Related
-
1993
- 1993-04-29 JP JP5518927A patent/JPH08500085A/ja active Pending
- 1993-04-29 AU AU40412/93A patent/AU4041293A/en not_active Abandoned
- 1993-04-29 EP EP93911509A patent/EP0639187A1/fr not_active Withdrawn
- 1993-04-29 WO PCT/EP1993/001071 patent/WO1993022304A1/fr not_active Application Discontinuation
- 1993-05-03 MA MA23182A patent/MA22889A1/fr unknown
- 1993-05-03 IL IL105586A patent/IL105586A0/xx unknown
- 1993-05-04 CN CN93107072A patent/CN1092418A/zh active Pending
- 1993-05-05 SI SI9300238A patent/SI9300238A/sl unknown
Also Published As
Publication number | Publication date |
---|---|
US5447954A (en) | 1995-09-05 |
IL105586A0 (en) | 1993-12-28 |
JPH08500085A (ja) | 1996-01-09 |
AU4041293A (en) | 1993-11-29 |
CN1092418A (zh) | 1994-09-21 |
GB9209628D0 (en) | 1992-06-17 |
WO1993022304A1 (fr) | 1993-11-11 |
SI9300238A (sl) | 1993-12-31 |
EP0639187A1 (fr) | 1995-02-22 |
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