MA20104A1 - Procede de preparation de dipeptides n-alcoyles et de leurs esters. - Google Patents

Procede de preparation de dipeptides n-alcoyles et de leurs esters.

Info

Publication number
MA20104A1
MA20104A1 MA20325A MA20325A MA20104A1 MA 20104 A1 MA20104 A1 MA 20104A1 MA 20325 A MA20325 A MA 20325A MA 20325 A MA20325 A MA 20325A MA 20104 A1 MA20104 A1 MA 20104A1
Authority
MA
Morocco
Prior art keywords
esters
preparation
dipeptides
alkyl
alkyl dipeptides
Prior art date
Application number
MA20325A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of MA20104A1 publication Critical patent/MA20104A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80—Antihypertensive peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
MA20325A 1983-04-28 1984-04-27 Procede de preparation de dipeptides n-alcoyles et de leurs esters. MA20104A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833315464 DE3315464A1 (de) 1983-04-28 1983-04-28 Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern

Publications (1)

Publication Number Publication Date
MA20104A1 true MA20104A1 (fr) 1984-12-31

Family

ID=6197624

Family Applications (1)

Application Number Title Priority Date Filing Date
MA20325A MA20104A1 (fr) 1983-04-28 1984-04-27 Procede de preparation de dipeptides n-alcoyles et de leurs esters.

Country Status (17)

Country Link
US (1) US4525301A (fr)
EP (1) EP0126986B1 (fr)
JP (2) JPH0655757B2 (fr)
KR (1) KR920001771B1 (fr)
AR (1) AR241709A1 (fr)
AT (1) ATE28753T1 (fr)
CA (2) CA1258148A (fr)
DE (2) DE3315464A1 (fr)
DK (2) DK171028B1 (fr)
ES (1) ES531926A0 (fr)
FI (1) FI80050C (fr)
GR (1) GR81965B (fr)
HU (1) HU194279B (fr)
IE (1) IE57287B1 (fr)
MA (1) MA20104A1 (fr)
NO (1) NO169591C (fr)
PT (1) PT78486B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766110A (en) * 1981-08-21 1988-08-23 Ryan James W Novel complex amido and imido derivatives of carboxyalkyl peptides
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
NZ202903A (en) * 1981-12-29 1988-01-08 Hoechst Ag 1-- pe pyrrol-2-yl-carboxylic acid derivatives and pharmaceutical compositions
US5175306A (en) * 1983-01-31 1992-12-29 Hoechst Aktiengesellschaft Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
FI841052A (fi) * 1983-03-16 1984-09-17 Usv Pharma Corp Foereningar foer behandling av blodtryckssjukdomar.
FR2546886B2 (fr) * 1983-06-06 1986-05-16 Adir Derives d'acides isoindoledicarboxyliques, leur preparation et compositions pharmaceutiques les contenant
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
DE3333454A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3408923A1 (de) * 1984-03-12 1985-09-26 Hoechst Ag, 6230 Frankfurt Carboxyalkyldipeptidderivate, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
CA1244041A (fr) * 1984-07-30 1988-11-01 Elijah H. Gold Procede de preparation du cis, endo-octahydrocyclopenta ¬b|pyrrole-2- carboxylate
US4801721A (en) * 1984-08-16 1989-01-31 Ryan James W Stereospecific synthesis of carboxyalkyl peptides
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US4691049A (en) * 1984-09-17 1987-09-01 Schering Corporation Process for preparing a specific diastereomer of a monoamino dicarboxylic acid ester
US4785003A (en) * 1984-10-16 1988-11-15 Biomeasure, Inc. N-disubstituted glycine and B-amino-propionic acid derivatives having anti-ulcer activity
US4785089A (en) * 1985-06-13 1988-11-15 Ciba-Geigy Corporation Novel sulfonic acid esters and their preparation
DE3582595D1 (de) * 1985-09-16 1991-05-23 Schering Corp Antihypertensive mittel, deren pharmazeutische zusammensetzungen und verfahren zur herstellung von mitteln und zusammensetzungen.
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
JPH0662671B2 (ja) * 1986-01-17 1994-08-17 株式会社大塚製薬工場 プロリン誘導体
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
DE3839127A1 (de) * 1988-11-19 1990-05-23 Hoechst Ag Pyrrolidon-2-carbonsaeure-derivate mit psychotroper wirkung
ES2136028B1 (es) * 1997-11-03 2000-07-01 Valles Rodoreda Martin Esteres del acido 2-(r)-fluorosulfoniloxi-4-fenibutirico, procedimiento para su obtencion y procedimiento para su utilizacion en la preparacion de carboxialquildipeptidos.
US6919450B2 (en) * 2001-03-27 2005-07-19 Ranbaxy Laboratories Limited Process for the preparation of benazepril
CA2363658C (fr) * 2001-11-21 2005-12-13 Brantford Chemicals Inc. Methode amelioree de preparation du ramipril
MXPA05010165A (es) * 2003-04-15 2005-11-16 Warner Lambert Co Derivados de prolina biciclicos [c]-condensados y su uso para el tratamiento de estados artriticos.
AU2005304664A1 (en) * 2004-11-05 2006-05-18 King Pharmaceuticals Research & Development, Inc. Stabilized ramipril compositions and methods of making
CN105693817B (zh) 2014-11-27 2020-06-05 西北大学 一类三肽化合物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3177130D1 (de) * 1980-08-30 1990-01-11 Hoechst Ag Aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung.
GB2128984B (en) * 1982-05-12 1985-05-22 Hoffmann La Roche Diaza-bicyclic compounds

Also Published As

Publication number Publication date
JPH0768213B2 (ja) 1995-07-26
DE3465202D1 (en) 1987-09-10
CA1258148A (fr) 1989-08-01
AR241709A1 (es) 1992-11-30
DE3315464A1 (de) 1984-10-31
HU194279B (en) 1988-01-28
NO841703L (no) 1984-10-29
CA1281330C (fr) 1991-03-12
DK171028B1 (da) 1996-04-22
GR81965B (fr) 1984-12-12
FI80050B (fi) 1989-12-29
PT78486A (de) 1984-05-01
ATE28753T1 (de) 1987-08-15
IE57287B1 (en) 1992-07-15
HUT34224A (en) 1985-02-28
EP0126986B1 (fr) 1987-08-05
JPH06184095A (ja) 1994-07-05
NO169591C (no) 1992-07-15
ES8502083A1 (es) 1984-12-16
JPS59206341A (ja) 1984-11-22
EP0126986A1 (fr) 1984-12-05
DK213184D0 (da) 1984-04-27
DK172685B1 (da) 1999-05-31
KR840009076A (ko) 1984-12-24
PT78486B (de) 1986-06-02
JPH0655757B2 (ja) 1994-07-27
FI841656A0 (fi) 1984-04-26
NO169591B (no) 1992-04-06
ES531926A0 (es) 1984-12-16
DK213184A (da) 1984-10-29
DK89392A (da) 1992-07-07
IE841049L (en) 1984-10-28
US4525301A (en) 1985-06-25
KR920001771B1 (ko) 1992-03-02
FI841656A (fi) 1984-10-29
FI80050C (fi) 1990-04-10
DK89392D0 (da) 1992-07-07

Similar Documents

Publication Publication Date Title
MA20104A1 (fr) Procede de preparation de dipeptides n-alcoyles et de leurs esters.
RO89714A (fr) Procede de preparation des derives de 5-methylthiopyrimidine
FR2490632B1 (fr) Derives de l-argininal et procede de preparation
MA20110A1 (fr) Procede de preparation de derives du cepheme.
BE887628A (fr) Procede de preparation de polyamines/amides
MA20226A1 (fr) Procede pour la preparation de dipeptides N-alcoyles et de leurs esters.
FR2555575B1 (fr) Procede de preparation de 4-alcoxyanilines
IT8448946A1 (it) Metodo e dispositivo per la fabbricazione di rulli.
FR2546907B1 (fr) Procede de production de la riboflavine
DK522784A (da) Forbedret forgaeringsproces
BE889546A (fr) Procede de preparation de n-cyclohexylbenzothiazole-2-sulfenamide
FR2550223B1 (fr) Spf-100 et procede de preparation
FR2550190B1 (fr) Procede de preparation de b-phenylserine
FR2549039B1 (fr) Procede de preparation de 3,3,3-trifluoro-2-trifluoro-mehylpropene
FR2534905B1 (fr) Procede de preparation de phenylcetones
IT8421110A0 (it) Procedimento e impianto per laproduzione di etanolo.
FR2528825B1 (fr) Procede de preparation de meta-chlorobenzotrifluorure
RO81430A (fr) Procede de preparation des azolul siliglycolethers
RO89126A (fr) Procede de preparation des derives de quinoleine
FR2550790B1 (fr) Procede de preparation de la 4-methylionone
MA20108A1 (fr) Procede de preparation de derives de cepheme
RO89010A (fr) Procede pour la preparation des esters thiazolidyniques substitus
FR2540108B1 (fr) Procede de preparation de perhalogenoalkylthioethers
FR2551435B1 (fr) Procede de preparation de la 6-demethyl-6-deoxy-6-methylene-5-oxytetracycline et de son derive 11a-chloro
FR2526021B1 (fr) Procede de preparation de 3-hydroxy-benzodiazepinones