LT3567124T - Genominių frakcijų paskirstymas, naudojant polimorfizmo skaičiavimo rezultatus - Google Patents
Genominių frakcijų paskirstymas, naudojant polimorfizmo skaičiavimo rezultatusInfo
- Publication number
- LT3567124T LT3567124T LTEP19178858.7T LT19178858T LT3567124T LT 3567124 T LT3567124 T LT 3567124T LT 19178858 T LT19178858 T LT 19178858T LT 3567124 T LT3567124 T LT 3567124T
- Authority
- LT
- Lithuania
- Prior art keywords
- polymorphism
- counts
- resolving
- genome fractions
- fractions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/10—Ploidy or copy number detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/10—Sequence alignment; Homology search
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B45/00—ICT specially adapted for bioinformatics-related data visualisation, e.g. displaying of maps or networks
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Evolutionary Biology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Data Mining & Analysis (AREA)
- Pathology (AREA)
- Evolutionary Computation (AREA)
- Bioethics (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Databases & Information Systems (AREA)
- Epidemiology (AREA)
- Artificial Intelligence (AREA)
- Public Health (AREA)
- Software Systems (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Algebra (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161474362P | 2011-04-12 | 2011-04-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
LT3567124T true LT3567124T (lt) | 2022-04-11 |
Family
ID=46001809
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP16158103.8T LT3078752T (lt) | 2011-04-12 | 2012-04-12 | Genomo frakcijų skaidymas, panaudojant polimorfizmo skaičiavimus |
LTEP19178858.7T LT3567124T (lt) | 2011-04-12 | 2012-04-12 | Genominių frakcijų paskirstymas, naudojant polimorfizmo skaičiavimo rezultatus |
LTEP18186518.9T LT3456844T (lt) | 2011-04-12 | 2012-04-12 | Genomo frakcijų išskirstymas, panaudojant polimorfizmo skaičiavimo duomenis |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP16158103.8T LT3078752T (lt) | 2011-04-12 | 2012-04-12 | Genomo frakcijų skaidymas, panaudojant polimorfizmo skaičiavimus |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP18186518.9T LT3456844T (lt) | 2011-04-12 | 2012-04-12 | Genomo frakcijų išskirstymas, panaudojant polimorfizmo skaičiavimo duomenis |
Country Status (20)
Country | Link |
---|---|
US (3) | US9447453B2 (lt) |
EP (5) | EP3078752B1 (lt) |
JP (3) | JP5863946B2 (lt) |
CN (2) | CN106319047B (lt) |
AU (1) | AU2012242698C1 (lt) |
CA (1) | CA2832468C (lt) |
CY (4) | CY1117574T1 (lt) |
DK (4) | DK3078752T3 (lt) |
ES (4) | ES2692333T3 (lt) |
HK (1) | HK1195103A1 (lt) |
HR (3) | HRP20220296T1 (lt) |
HU (3) | HUE057424T2 (lt) |
IL (1) | IL228843A (lt) |
LT (3) | LT3078752T (lt) |
PL (4) | PL2697392T3 (lt) |
PT (3) | PT3078752T (lt) |
RS (3) | RS57837B1 (lt) |
SI (3) | SI3456844T1 (lt) |
TR (1) | TR201816062T4 (lt) |
WO (1) | WO2012142334A2 (lt) |
Families Citing this family (104)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
US10083273B2 (en) | 2005-07-29 | 2018-09-25 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
US10081839B2 (en) | 2005-07-29 | 2018-09-25 | Natera, Inc | System and method for cleaning noisy genetic data and determining chromosome copy number |
US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
ES2620431T3 (es) | 2008-08-04 | 2017-06-28 | Natera, Inc. | Métodos para la determinación de alelos y de ploidía |
US20120185176A1 (en) | 2009-09-30 | 2012-07-19 | Natera, Inc. | Methods for Non-Invasive Prenatal Ploidy Calling |
US9323888B2 (en) | 2010-01-19 | 2016-04-26 | Verinata Health, Inc. | Detecting and classifying copy number variation |
US9260745B2 (en) | 2010-01-19 | 2016-02-16 | Verinata Health, Inc. | Detecting and classifying copy number variation |
US10388403B2 (en) | 2010-01-19 | 2019-08-20 | Verinata Health, Inc. | Analyzing copy number variation in the detection of cancer |
US20120100548A1 (en) | 2010-10-26 | 2012-04-26 | Verinata Health, Inc. | Method for determining copy number variations |
WO2011091063A1 (en) | 2010-01-19 | 2011-07-28 | Verinata Health, Inc. | Partition defined detection methods |
EP2848703A1 (en) | 2010-01-19 | 2015-03-18 | Verinata Health, Inc | Simultaneous determination of aneuploidy and fetal fraction |
US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
CA3037126C (en) | 2010-05-18 | 2023-09-12 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
US11031095B2 (en) | 2010-08-06 | 2021-06-08 | Ariosa Diagnostics, Inc. | Assay systems for determination of fetal copy number variation |
US20120034603A1 (en) | 2010-08-06 | 2012-02-09 | Tandem Diagnostics, Inc. | Ligation-based detection of genetic variants |
US20130261003A1 (en) | 2010-08-06 | 2013-10-03 | Ariosa Diagnostics, In. | Ligation-based detection of genetic variants |
US20130040375A1 (en) | 2011-08-08 | 2013-02-14 | Tandem Diagnotics, Inc. | Assay systems for genetic analysis |
US20140342940A1 (en) | 2011-01-25 | 2014-11-20 | Ariosa Diagnostics, Inc. | Detection of Target Nucleic Acids using Hybridization |
US10533223B2 (en) | 2010-08-06 | 2020-01-14 | Ariosa Diagnostics, Inc. | Detection of target nucleic acids using hybridization |
US8700338B2 (en) | 2011-01-25 | 2014-04-15 | Ariosa Diagnosis, Inc. | Risk calculation for evaluation of fetal aneuploidy |
US10167508B2 (en) | 2010-08-06 | 2019-01-01 | Ariosa Diagnostics, Inc. | Detection of genetic abnormalities |
US11203786B2 (en) | 2010-08-06 | 2021-12-21 | Ariosa Diagnostics, Inc. | Detection of target nucleic acids using hybridization |
JP6328934B2 (ja) | 2010-12-22 | 2018-05-23 | ナテラ, インコーポレイテッド | 非侵襲性出生前親子鑑定法 |
US8756020B2 (en) | 2011-01-25 | 2014-06-17 | Ariosa Diagnostics, Inc. | Enhanced risk probabilities using biomolecule estimations |
US9994897B2 (en) | 2013-03-08 | 2018-06-12 | Ariosa Diagnostics, Inc. | Non-invasive fetal sex determination |
US10131947B2 (en) | 2011-01-25 | 2018-11-20 | Ariosa Diagnostics, Inc. | Noninvasive detection of fetal aneuploidy in egg donor pregnancies |
US11270781B2 (en) | 2011-01-25 | 2022-03-08 | Ariosa Diagnostics, Inc. | Statistical analysis for non-invasive sex chromosome aneuploidy determination |
JP6153874B2 (ja) | 2011-02-09 | 2017-06-28 | ナテラ, インコーポレイテッド | 非侵襲的出生前倍数性呼び出しのための方法 |
CA2827873C (en) * | 2011-02-24 | 2022-08-16 | The Chinese University Of Hong Kong | Molecular testing of multiple pregnancies |
RS57837B1 (sr) | 2011-04-12 | 2018-12-31 | Verinata Health Inc | Razrešavanje genomskih frakcija upotrebom broja kopija polimorfizama |
WO2014014498A1 (en) | 2012-07-20 | 2014-01-23 | Verinata Health, Inc. | Detecting and classifying copy number variation in a fetal genome |
US9411937B2 (en) | 2011-04-15 | 2016-08-09 | Verinata Health, Inc. | Detecting and classifying copy number variation |
US8712697B2 (en) | 2011-09-07 | 2014-04-29 | Ariosa Diagnostics, Inc. | Determination of copy number variations using binomial probability calculations |
ES2651612T3 (es) | 2011-10-18 | 2018-01-29 | Multiplicom Nv | Diagnóstico de aneuploidía cromosómica fetal |
US10289800B2 (en) | 2012-05-21 | 2019-05-14 | Ariosa Diagnostics, Inc. | Processes for calculating phased fetal genomic sequences |
WO2014015269A1 (en) | 2012-07-19 | 2014-01-23 | Ariosa Diagnostics, Inc. | Multiplexed sequential ligation-based detection of genetic variants |
EP3561072A1 (en) | 2012-12-10 | 2019-10-30 | Resolution Bioscience, Inc. | Methods for targeted genomic analysis |
WO2014151117A1 (en) | 2013-03-15 | 2014-09-25 | The Board Of Trustees Of The Leland Stanford Junior University | Identification and use of circulating nucleic acid tumor markers |
GB201304810D0 (en) * | 2013-03-15 | 2013-05-01 | Isis Innovation | Assay |
KR102665592B1 (ko) | 2013-05-24 | 2024-05-21 | 시쿼넘, 인코포레이티드 | 유전적 변이의 비침습 평가를 위한 방법 및 프로세스 |
WO2015026967A1 (en) * | 2013-08-20 | 2015-02-26 | Natera, Inc. | Methods of using low fetal fraction detection |
US20170132364A1 (en) * | 2013-09-03 | 2017-05-11 | Welgene Biotech Co., Ltd. | Non-invasive prenatal testing method based on genome-wide normalized score |
US10262755B2 (en) | 2014-04-21 | 2019-04-16 | Natera, Inc. | Detecting cancer mutations and aneuploidy in chromosomal segments |
US10577655B2 (en) | 2013-09-27 | 2020-03-03 | Natera, Inc. | Cell free DNA diagnostic testing standards |
US9499870B2 (en) | 2013-09-27 | 2016-11-22 | Natera, Inc. | Cell free DNA diagnostic testing standards |
WO2015042649A1 (en) * | 2013-09-27 | 2015-04-02 | Murdoch Children's Research Institute | A quantitative assay for target dna in a mixed sample comprising target and non-target dna |
RU2543155C1 (ru) * | 2014-02-03 | 2015-02-27 | Закрытое акционерное общество "Геноаналитика" | Способ неинвазивной диагностики анеуплоидий плода методом секвенирования |
US10741291B2 (en) * | 2014-03-27 | 2020-08-11 | The Scripps Research Institute | Systems and methods for genomic annotation and distributed variant interpretation |
EP3134541B1 (en) | 2014-04-21 | 2020-08-19 | Natera, Inc. | Detecting copy number variations (cnv) of chromosomal segments in cancer |
WO2016019042A1 (en) | 2014-07-30 | 2016-02-04 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
JP7441584B6 (ja) * | 2014-08-22 | 2024-03-15 | レゾリューション バイオサイエンス, インコーポレイテッド | 無細胞DNA(cfDNA)の定量的遺伝子解析のための方法 |
US10006910B2 (en) | 2014-12-18 | 2018-06-26 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
WO2016100049A1 (en) | 2014-12-18 | 2016-06-23 | Edico Genome Corporation | Chemically-sensitive field effect transistor |
US9618474B2 (en) | 2014-12-18 | 2017-04-11 | Edico Genome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
US9859394B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
US10020300B2 (en) | 2014-12-18 | 2018-07-10 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
US9857328B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same |
WO2016183106A1 (en) | 2015-05-11 | 2016-11-17 | Natera, Inc. | Methods and compositions for determining ploidy |
JP2018517421A (ja) * | 2015-06-15 | 2018-07-05 | マードック チルドレンズ リサーチ インスティチュート | キメリズムを測定する方法 |
BE1023274A9 (nl) * | 2015-07-17 | 2017-03-17 | Multiplicom Nv | Schattingswerkwijze en -systeem voor het schatten van een foetale fractie |
WO2017050244A1 (en) * | 2015-09-22 | 2017-03-30 | The Chinese University Of Hong Kong | Accurate quantification of fetal dna fraction by shallow-depth sequencing of maternal plasma dna |
BE1022771B1 (nl) * | 2015-10-14 | 2016-08-31 | Multiplicom Nv | Werkwijze en systeem om te bepalen of een vrouw zwanger is op basis van een bloedstaal |
DK3374525T3 (da) | 2015-11-11 | 2021-04-06 | Resolution Bioscience Inc | Højeffektiv konstruktion af dna-biblioteker |
EP4071250A1 (en) | 2016-03-22 | 2022-10-12 | Myriad Women's Health, Inc. | Combinatorial dna screening |
WO2017201081A1 (en) | 2016-05-16 | 2017-11-23 | Agilome, Inc. | Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids |
EP3504347A4 (en) | 2016-08-25 | 2020-04-29 | Resolution Bioscience, Inc. | METHODS FOR DETECTING GENOMIC COPY CHANGES IN DNA SAMPLES |
WO2018064486A1 (en) | 2016-09-29 | 2018-04-05 | Counsyl, Inc. | Noninvasive prenatal screening using dynamic iterative depth optimization |
WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
CN109996894A (zh) * | 2016-11-18 | 2019-07-09 | 香港中文大学 | 用于单基因疾病的基于通用单倍型的非侵入性产前测试 |
US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
GB2559319B (en) | 2016-12-23 | 2019-01-16 | Cs Genetics Ltd | Reagents and methods for the analysis of linked nucleic acids |
JP7237003B2 (ja) | 2017-01-24 | 2023-03-10 | セクエノム, インコーポレイテッド | 遺伝子片の評価のための方法およびプロセス |
RU2636618C1 (ru) * | 2017-02-14 | 2017-11-24 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова" Министерства здравоохранения Российской Федерации | Способ и тест-система для определения доли плодовой ДНК в плазме крови беременной женщины с помощью методов высокопроизводительного секвенирования |
US12006533B2 (en) * | 2017-02-17 | 2024-06-11 | Grail, Llc | Detecting cross-contamination in sequencing data using regression techniques |
WO2018156418A1 (en) | 2017-02-21 | 2018-08-30 | Natera, Inc. | Compositions, methods, and kits for isolating nucleic acids |
US20200087710A1 (en) * | 2017-03-17 | 2020-03-19 | Sequenom, Inc. | Methods and processes for assessment of genetic mosaicism |
KR102145417B1 (ko) * | 2017-05-24 | 2020-08-19 | 지니너스 주식회사 | 무세포 핵산으로부터 수득된 서열 분석 데이터에 대한 배경 대립인자의 빈도 분포를 생성하는 방법 및 이를 이용하여 무세포 핵산으로부터 변이를 검출하는 방법 |
KR102543270B1 (ko) * | 2017-06-20 | 2023-06-13 | 일루미나, 인코포레이티드 | 미지의 유전자형의 기여자로부터의 dna 혼합물의 정확한 컴퓨팅 분해를 위한 방법 |
SG11201911538YA (en) * | 2017-06-20 | 2020-01-30 | Illumina Inc | Methods and systems for decomposition and quantification of dna mixtures from multiple contributors of known or unknown genotypes |
CN108220451B (zh) * | 2017-12-08 | 2020-10-27 | 北京科迅生物技术有限公司 | 胎儿游离核酸浓度的检测方法及试剂盒 |
US12024738B2 (en) | 2018-04-14 | 2024-07-02 | Natera, Inc. | Methods for cancer detection and monitoring |
GB201810571D0 (en) | 2018-06-27 | 2018-08-15 | Cs Genetics Ltd | Reagents and methods for the analysis of circulating microparticles |
US11525159B2 (en) | 2018-07-03 | 2022-12-13 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
ES2738176B2 (es) * | 2018-07-20 | 2021-01-11 | Bioarray S L | Metodo para el estudio de mutaciones en embriones en procesos de reproduccion in vitro |
CN109378037B (zh) * | 2018-10-31 | 2023-04-14 | 中国石油大学(华东) | 基于遗传学规律的等位基因准确推断方法 |
US20200381079A1 (en) * | 2019-06-03 | 2020-12-03 | Illumina, Inc. | Methods for determining sub-genic copy numbers of a target gene with close homologs using beadarray |
GB201909325D0 (en) | 2019-06-28 | 2019-08-14 | Cs Genetics Ltd | Reagents and methods for analysis for microparticles |
CN110438220A (zh) * | 2019-08-16 | 2019-11-12 | 深圳市人民医院 | 纤毛不动综合症基因面板试剂盒及其应用 |
US11946104B2 (en) | 2020-07-07 | 2024-04-02 | Billiontoone, Inc. | Non-invasive prenatal testing at early stage of pregnancy |
CN113345515B (zh) * | 2021-06-17 | 2024-05-31 | 苏州贝康医疗器械有限公司 | 新发平衡易位家系中胚胎遗传性检测方法及装置 |
CN113667734B (zh) * | 2021-07-16 | 2022-05-24 | 四川大学华西医院 | Shank3片段序列甲基化检测试剂在制备精神***症诊断试剂盒中的用途 |
WO2023014597A1 (en) | 2021-08-02 | 2023-02-09 | Natera, Inc. | Methods for detecting neoplasm in pregnant women |
WO2023158596A1 (en) | 2022-02-16 | 2023-08-24 | Illumina, Inc. | Minimizing fetal fraction bias in maternal polygenic risk score estimation |
Family Cites Families (88)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6270961B1 (en) | 1987-04-01 | 2001-08-07 | Hyseq, Inc. | Methods and apparatus for DNA sequencing and DNA identification |
US5965362A (en) | 1992-03-04 | 1999-10-12 | The Regents Of The University Of California | Comparative genomic hybridization (CGH) |
WO1994003638A1 (en) | 1992-07-30 | 1994-02-17 | Applied Biosystems, Inc. | Method of detecting aneuploidy by amplified short tandem repeats |
US5776737A (en) | 1994-12-22 | 1998-07-07 | Visible Genetics Inc. | Method and composition for internal identification of samples |
US6057103A (en) | 1995-07-18 | 2000-05-02 | Diversa Corporation | Screening for novel bioactivities |
ES2401121T3 (es) | 1996-10-04 | 2013-04-17 | Veri-Q Inc. | Dispositivos de recolección de muestras y métodos que utilizan marcadores y el uso de dichos marcadores como controles en la validación de una muestra, evaluación y/o certificación de laboratorio |
GB9704444D0 (en) | 1997-03-04 | 1997-04-23 | Isis Innovation | Non-invasive prenatal diagnosis |
DE69837913T2 (de) | 1997-04-01 | 2008-02-07 | Solexa Ltd., Saffron Walden | Verfahren zur vervielfältigung von nukleinsäure |
AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
US6440706B1 (en) | 1999-08-02 | 2002-08-27 | Johns Hopkins University | Digital amplification |
US20020142324A1 (en) | 2000-09-22 | 2002-10-03 | Xun Wang | Fungal target genes and methods to identify those genes |
US6691042B2 (en) | 2001-07-02 | 2004-02-10 | Rosetta Inpharmatics Llc | Methods for generating differential profiles by combining data obtained in separate measurements |
US7226732B2 (en) | 2001-07-16 | 2007-06-05 | Cepheid | Methods, apparatus, and computer programs for verifying the integrity of a probe |
US6927028B2 (en) * | 2001-08-31 | 2005-08-09 | Chinese University Of Hong Kong | Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA |
US7893248B2 (en) | 2002-02-20 | 2011-02-22 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA) |
US6977162B2 (en) | 2002-03-01 | 2005-12-20 | Ravgen, Inc. | Rapid analysis of variations in a genome |
CA2477761A1 (en) | 2002-03-01 | 2003-09-12 | Ravgen, Inc. | Methods for detection of genetic disorders |
US20030194704A1 (en) | 2002-04-03 | 2003-10-16 | Penn Sharron Gaynor | Human genome-derived single exon nucleic acid probes useful for gene expression analysis two |
US7727720B2 (en) * | 2002-05-08 | 2010-06-01 | Ravgen, Inc. | Methods for detection of genetic disorders |
EP2359689B1 (en) | 2002-09-27 | 2015-08-26 | The General Hospital Corporation | Microfluidic device for cell separation and use thereof |
US10229244B2 (en) | 2002-11-11 | 2019-03-12 | Affymetrix, Inc. | Methods for identifying DNA copy number changes using hidden markov model based estimations |
US20040224331A1 (en) | 2003-01-17 | 2004-11-11 | The Trustees Of Boston University | Haplotype analysis |
US8394582B2 (en) | 2003-03-05 | 2013-03-12 | Genetic Technologies, Inc | Identification of fetal DNA and fetal cell markers in maternal plasma or serum |
EP1606417A2 (en) | 2003-03-07 | 2005-12-21 | Rubicon Genomics Inc. | In vitro dna immortalization and whole genome amplification using libraries generated from randomly fragmented dna |
WO2005023091A2 (en) | 2003-09-05 | 2005-03-17 | The Trustees Of Boston University | Method for non-invasive prenatal diagnosis |
US20050221341A1 (en) | 2003-10-22 | 2005-10-06 | Shimkets Richard A | Sequence-based karyotyping |
US20050114205A1 (en) * | 2003-11-21 | 2005-05-26 | Kenneth Nelson | Multi-media digital cartridge storage and playback units |
WO2005072133A2 (en) | 2004-01-27 | 2005-08-11 | Zoragen, Inc. | Nucleic acid detection |
US20100216151A1 (en) | 2004-02-27 | 2010-08-26 | Helicos Biosciences Corporation | Methods for detecting fetal nucleic acids and diagnosing fetal abnormalities |
US20060046258A1 (en) | 2004-02-27 | 2006-03-02 | Lapidus Stanley N | Applications of single molecule sequencing |
US20100216153A1 (en) * | 2004-02-27 | 2010-08-26 | Helicos Biosciences Corporation | Methods for detecting fetal nucleic acids and diagnosing fetal abnormalities |
WO2005116257A2 (en) | 2004-05-17 | 2005-12-08 | The Ohio State University Research Foundation | Unique short tandem repeats and methods of their use |
DE102004036285A1 (de) | 2004-07-27 | 2006-02-16 | Advalytix Ag | Verfahren zum Bestimmen der Häufigkeit von Sequenzen einer Probe |
JP2007327743A (ja) | 2004-09-07 | 2007-12-20 | Univ Of Tokyo | 遺伝子コピーの解析方法及び装置 |
TW200624106A (en) | 2004-09-07 | 2006-07-16 | Uni Charm Corp | Warming article |
US20060286566A1 (en) * | 2005-02-03 | 2006-12-21 | Helicos Biosciences Corporation | Detecting apparent mutations in nucleic acid sequences |
US20060178835A1 (en) | 2005-02-10 | 2006-08-10 | Applera Corporation | Normalization methods for genotyping analysis |
CA2601221C (en) | 2005-03-18 | 2013-08-06 | The Chinese University Of Hong Kong | A method for the detection of chromosomal aneuploidies |
CA2611409A1 (en) | 2005-06-08 | 2006-12-14 | Compugen Ltd. | Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis |
US20060286558A1 (en) | 2005-06-15 | 2006-12-21 | Natalia Novoradovskaya | Normalization of samples for amplification reactions |
US8532930B2 (en) | 2005-11-26 | 2013-09-10 | Natera, Inc. | Method for determining the number of copies of a chromosome in the genome of a target individual using genetic data from genetically related individuals |
DE102005057988A1 (de) | 2005-08-04 | 2007-02-08 | Bosch Rexroth Ag | Axialkolbenmaschine |
ES2739484T3 (es) | 2006-02-02 | 2020-01-31 | Univ Leland Stanford Junior | Prueba genética fetal no invasiva mediante análisis digital |
US20100184043A1 (en) * | 2006-02-28 | 2010-07-22 | University Of Louisville Research Foundation | Detecting Genetic Abnormalities |
CA2647793C (en) | 2006-02-28 | 2016-07-05 | University Of Louisville Research Foundation | Detecting fetal chromosomal abnormalities using tandem single nucleotide polymorphisms |
WO2007146106A2 (en) | 2006-06-05 | 2007-12-21 | Cryo- Cell International, Inc. | Procurement, isolation and cryopreservation of maternal placental cells |
EP2589668A1 (en) | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Rare cell analysis using sample splitting and DNA tags |
US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
CA2655272C (en) | 2006-06-14 | 2017-04-18 | Living Microsystems, Inc. | Rare cell analysis using sample splitting and dna tags |
US20080070792A1 (en) | 2006-06-14 | 2008-03-20 | Roland Stoughton | Use of highly parallel snp genotyping for fetal diagnosis |
US9328378B2 (en) | 2006-07-31 | 2016-05-03 | Illumina Cambridge Limited | Method of library preparation avoiding the formation of adaptor dimers |
US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
CA2677517C (en) | 2007-02-08 | 2015-11-03 | Sequenom, Inc. | Nucleic acid-based tests for rhd typing, gender determination and nucleic acid quantification |
CA2900927C (en) | 2007-07-23 | 2018-08-14 | The Chinese University Of Hong Kong | Diagnosing fetal chromosomal aneuploidy using genomic sequencing |
US20100112590A1 (en) | 2007-07-23 | 2010-05-06 | The Chinese University Of Hong Kong | Diagnosing Fetal Chromosomal Aneuploidy Using Genomic Sequencing With Enrichment |
CN101889074A (zh) | 2007-10-04 | 2010-11-17 | 哈尔西恩莫尔丘勒公司 | 采用电子显微镜对核酸聚合物测序 |
AU2009223671B2 (en) * | 2008-03-11 | 2014-11-27 | Sequenom, Inc. | Nucleic acid-based tests for prenatal gender determination |
US20090307180A1 (en) | 2008-03-19 | 2009-12-10 | Brandon Colby | Genetic analysis |
CA2718137A1 (en) | 2008-03-26 | 2009-10-01 | Sequenom, Inc. | Restriction endonuclease enhanced polymorphic sequence detection |
US20090270601A1 (en) | 2008-04-21 | 2009-10-29 | Steven Albert Benner | Differential detection of single nucleotide polymorphisms |
ES2532153T3 (es) | 2008-07-18 | 2015-03-24 | Trovagene, Inc. | Métodos para la detección de secuencias de ácidos nucleicos "ultracortos" basados en PCR |
CA3069082C (en) | 2008-09-20 | 2022-03-22 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
US20100285537A1 (en) | 2009-04-02 | 2010-11-11 | Fluidigm Corporation | Selective tagging of short nucleic acid fragments and selective protection of target sequences from degradation |
EP2494065B1 (en) | 2009-10-26 | 2015-12-23 | Lifecodexx AG | Means and methods for non-invasive diagnosis of chromosomal aneuploidy |
ES2720282T3 (es) * | 2009-11-05 | 2019-07-19 | Univ Hong Kong Chinese | Análisis genómico fetal a partir de una muestra biológica materna |
CN102597272A (zh) | 2009-11-12 | 2012-07-18 | 艾索特里克斯遗传实验室有限责任公司 | 基因座的拷贝数分析 |
WO2011091063A1 (en) | 2010-01-19 | 2011-07-28 | Verinata Health, Inc. | Partition defined detection methods |
US9260745B2 (en) | 2010-01-19 | 2016-02-16 | Verinata Health, Inc. | Detecting and classifying copy number variation |
WO2011090556A1 (en) * | 2010-01-19 | 2011-07-28 | Verinata Health, Inc. | Methods for determining fraction of fetal nucleic acid in maternal samples |
US9323888B2 (en) | 2010-01-19 | 2016-04-26 | Verinata Health, Inc. | Detecting and classifying copy number variation |
US20120100548A1 (en) | 2010-10-26 | 2012-04-26 | Verinata Health, Inc. | Method for determining copy number variations |
AU2011207544A1 (en) | 2010-01-19 | 2012-09-06 | Verinata Health, Inc. | Identification of polymorphic sequences in mixtures of genomic DNA by whole genome sequencing |
EP2848703A1 (en) | 2010-01-19 | 2015-03-18 | Verinata Health, Inc | Simultaneous determination of aneuploidy and fetal fraction |
US10388403B2 (en) | 2010-01-19 | 2019-08-20 | Verinata Health, Inc. | Analyzing copy number variation in the detection of cancer |
US20120237928A1 (en) | 2010-10-26 | 2012-09-20 | Verinata Health, Inc. | Method for determining copy number variations |
US20110312503A1 (en) | 2010-01-23 | 2011-12-22 | Artemis Health, Inc. | Methods of fetal abnormality detection |
WO2012012037A1 (en) | 2010-07-19 | 2012-01-26 | New England Biolabs, Inc. | Oligonucleotide adaptors: compositions and methods of use |
US20120034603A1 (en) | 2010-08-06 | 2012-02-09 | Tandem Diagnostics, Inc. | Ligation-based detection of genetic variants |
EP4269623A3 (en) | 2010-11-30 | 2024-03-06 | The Chinese University Of Hong Kong | Analysis of a biological sample of an organism for chromosomal deletions or amplifications associated with cancer |
CN103620055A (zh) | 2010-12-07 | 2014-03-05 | 利兰·斯坦福青年大学托管委员会 | 在全基因组规模非侵入性确定亲本单倍型的胎儿遗传 |
WO2012088348A2 (en) | 2010-12-23 | 2012-06-28 | Sequenom, Inc. | Fetal genetic variation detection |
US20120190021A1 (en) * | 2011-01-25 | 2012-07-26 | Aria Diagnostics, Inc. | Detection of genetic abnormalities |
JP6153874B2 (ja) | 2011-02-09 | 2017-06-28 | ナテラ, インコーポレイテッド | 非侵襲的出生前倍数性呼び出しのための方法 |
RS57837B1 (sr) | 2011-04-12 | 2018-12-31 | Verinata Health Inc | Razrešavanje genomskih frakcija upotrebom broja kopija polimorfizama |
GB2484764B (en) | 2011-04-14 | 2012-09-05 | Verinata Health Inc | Normalizing chromosomes for the determination and verification of common and rare chromosomal aneuploidies |
US9411937B2 (en) | 2011-04-15 | 2016-08-09 | Verinata Health, Inc. | Detecting and classifying copy number variation |
GB2485635B (en) | 2011-07-26 | 2012-11-28 | Verinata Health Inc | Method for determining the presence or absence of different aneuploidies in a sample |
-
2012
- 2012-04-12 RS RS20181302A patent/RS57837B1/sr unknown
- 2012-04-12 HU HUE19178858A patent/HUE057424T2/hu unknown
- 2012-04-12 CA CA2832468A patent/CA2832468C/en active Active
- 2012-04-12 ES ES16158103.8T patent/ES2692333T3/es active Active
- 2012-04-12 LT LTEP16158103.8T patent/LT3078752T/lt unknown
- 2012-04-12 DK DK16158103.8T patent/DK3078752T3/en active
- 2012-04-12 ES ES19178858T patent/ES2907069T3/es active Active
- 2012-04-12 SI SI201231813T patent/SI3456844T1/sl unknown
- 2012-04-12 PL PL12716939T patent/PL2697392T3/pl unknown
- 2012-04-12 DK DK19178858.7T patent/DK3567124T3/da active
- 2012-04-12 PT PT16158103T patent/PT3078752T/pt unknown
- 2012-04-12 SI SI201231416T patent/SI3078752T1/sl unknown
- 2012-04-12 HU HUE16158103A patent/HUE041411T2/hu unknown
- 2012-04-12 DK DK18186518.9T patent/DK3456844T3/da active
- 2012-04-12 RS RS20200985A patent/RS60710B1/sr unknown
- 2012-04-12 EP EP16158103.8A patent/EP3078752B1/en not_active Revoked
- 2012-04-12 US US13/445,778 patent/US9447453B2/en active Active
- 2012-04-12 HR HRP20220296TT patent/HRP20220296T1/hr unknown
- 2012-04-12 JP JP2014505313A patent/JP5863946B2/ja active Active
- 2012-04-12 CN CN201610697158.8A patent/CN106319047B/zh active Active
- 2012-04-12 ES ES12716939.9T patent/ES2572912T3/es active Active
- 2012-04-12 DK DK12716939.9T patent/DK2697392T3/en active
- 2012-04-12 LT LTEP19178858.7T patent/LT3567124T/lt unknown
- 2012-04-12 LT LTEP18186518.9T patent/LT3456844T/lt unknown
- 2012-04-12 HU HUE18186518A patent/HUE050032T2/hu unknown
- 2012-04-12 PL PL18186518T patent/PL3456844T3/pl unknown
- 2012-04-12 PL PL19178858T patent/PL3567124T3/pl unknown
- 2012-04-12 PT PT191788587T patent/PT3567124T/pt unknown
- 2012-04-12 EP EP21213624.6A patent/EP4039820A1/en active Pending
- 2012-04-12 PT PT181865189T patent/PT3456844T/pt unknown
- 2012-04-12 EP EP18186518.9A patent/EP3456844B1/en active Active
- 2012-04-12 ES ES18186518T patent/ES2806728T3/es active Active
- 2012-04-12 WO PCT/US2012/033391 patent/WO2012142334A2/en active Application Filing
- 2012-04-12 EP EP12716939.9A patent/EP2697392B1/en active Active
- 2012-04-12 RS RS20220224A patent/RS63008B1/sr unknown
- 2012-04-12 SI SI201231986T patent/SI3567124T1/sl unknown
- 2012-04-12 PL PL16158103T patent/PL3078752T3/pl unknown
- 2012-04-12 AU AU2012242698A patent/AU2012242698C1/en active Active
- 2012-04-12 CN CN201280028976.9A patent/CN103797129B/zh active Active
- 2012-04-12 TR TR2018/16062T patent/TR201816062T4/tr unknown
- 2012-04-12 EP EP19178858.7A patent/EP3567124B1/en active Active
-
2013
- 2013-10-13 IL IL228843A patent/IL228843A/en active IP Right Grant
-
2014
- 2014-08-18 HK HK14108407.4A patent/HK1195103A1/zh unknown
-
2015
- 2015-12-22 JP JP2015249239A patent/JP6268153B2/ja active Active
-
2016
- 2016-05-30 CY CY20161100473T patent/CY1117574T1/el unknown
- 2016-08-11 US US15/234,966 patent/US10658070B2/en active Active
-
2017
- 2017-12-25 JP JP2017247208A patent/JP6760917B2/ja active Active
-
2018
- 2018-10-26 HR HRP20181770TT patent/HRP20181770T1/hr unknown
- 2018-10-30 CY CY181101123T patent/CY1120851T1/el unknown
-
2020
- 2020-04-20 US US16/853,347 patent/US20200251180A1/en active Pending
- 2020-08-10 HR HRP20201249TT patent/HRP20201249T1/hr unknown
- 2020-08-27 CY CY20201100805T patent/CY1123287T1/el unknown
-
2022
- 2022-03-09 CY CY20221100193T patent/CY1125362T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HRP20181770T1 (hr) | Rješavanje genomskih frakcija upotrebom broja kopija polimorfizama | |
IL231983B (en) | Dna containing tricyclo-phosphorothioate | |
LT2742151T (lt) | Polimerazės kompozicija | |
EP2726548A4 (en) | HARDENING COMPOSITIONS | |
EP2682432A4 (en) | HARDENING COMPOSITION | |
EP2735590A4 (en) | HARDENING COMPOSITION | |
GB201118636D0 (en) | Nucleotide sequence | |
EP2662410A4 (en) | CURABLE COMPOSITION | |
EP2784124A4 (en) | HARDENING COMPOSITION | |
EP2784123A4 (en) | CURABLE COMPOSITION | |
EP2784128A4 (en) | HARDENING COMPOSITION | |
EP2784127A4 (en) | HARDENING COMPOSITION | |
EP2722366A4 (en) | HARDENING COMPOSITION | |
EP2662413A4 (en) | CURABLE COMPOSITION | |
EP2784125A4 (en) | CURABLE COMPOSITION | |
EP2662411A4 (en) | CURABLE COMPOSITION | |
EP2662412A4 (en) | HARDENING COMPOSITION | |
EP2784126A4 (en) | CURABLE COMPOSITION | |
TWI561573B (en) | Curable compositions | |
EP2663657A4 (en) | GENOMIC ASSEMBLY | |
EP2706095A4 (en) | HARDENING COMPOSITION | |
GB201204205D0 (en) | Alcohol-containing compositions | |
GB201112355D0 (en) | DNA screening | |
GB201208808D0 (en) | Novel Consumable | |
GB201216870D0 (en) | dna screening |