LT3436022T - Oxysterols and methods of use thereof - Google Patents

Oxysterols and methods of use thereof

Info

Publication number
LT3436022T
LT3436022T LTEPPCT/US2017/025535T LTUS2017025535T LT3436022T LT 3436022 T LT3436022 T LT 3436022T LT US2017025535 T LTUS2017025535 T LT US2017025535T LT 3436022 T LT3436022 T LT 3436022T
Authority
LT
Lithuania
Prior art keywords
oxysterols
methods
Prior art date
Application number
LTEPPCT/US2017/025535T
Other languages
Lithuanian (lt)
Inventor
Albert Robichaud
Francesco Salituro
Gabriel MARTINEZBOTELLA
Boyd Harrison
John Reid
Original Assignee
Sage Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sage Therapeutics, Inc. filed Critical Sage Therapeutics, Inc.
Publication of LT3436022T publication Critical patent/LT3436022T/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
LTEPPCT/US2017/025535T 2016-04-01 2017-03-31 Oxysterols and methods of use thereof LT3436022T (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662317002P 2016-04-01 2016-04-01
PCT/US2017/025535 WO2017173358A1 (en) 2016-04-01 2017-03-31 Oxysterols and methods of use thereof

Publications (1)

Publication Number Publication Date
LT3436022T true LT3436022T (en) 2022-06-27

Family

ID=59965335

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/US2017/025535T LT3436022T (en) 2016-04-01 2017-03-31 Oxysterols and methods of use thereof

Country Status (19)

Country Link
US (2) US20190330259A1 (en)
EP (1) EP3436022B1 (en)
JP (3) JP7112331B2 (en)
CN (2) CN109195604B (en)
AU (2) AU2017240157B2 (en)
BR (1) BR112018070123A2 (en)
CA (1) CA3019146C (en)
DK (1) DK3436022T3 (en)
ES (1) ES2921010T3 (en)
HR (1) HRP20220716T1 (en)
HU (1) HUE059491T2 (en)
LT (1) LT3436022T (en)
MA (1) MA44526A (en)
PL (1) PL3436022T3 (en)
PT (1) PT3436022T (en)
RS (1) RS63280B1 (en)
RU (1) RU2754130C2 (en)
SI (1) SI3436022T1 (en)
WO (1) WO2017173358A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3461834T3 (en) 2013-03-13 2021-08-23 Sage Therapeutics Inc NEUROACTIVE STEROIDS
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WO2023114224A1 (en) 2021-12-13 2023-06-22 Sage Therapeutics, Inc. Combination of muscarinic receptor positive modulators and nmda positive allosteric modulators

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Also Published As

Publication number Publication date
US20190330259A1 (en) 2019-10-31
DK3436022T3 (en) 2022-06-20
EP3436022A1 (en) 2019-02-06
JP2023126904A (en) 2023-09-12
AU2022291419A1 (en) 2023-02-02
PL3436022T3 (en) 2022-08-08
US11884697B2 (en) 2024-01-30
JP7112331B2 (en) 2022-08-03
CN114272249A (en) 2022-04-05
PT3436022T (en) 2022-07-04
JP2021167334A (en) 2021-10-21
EP3436022A4 (en) 2019-11-27
RS63280B1 (en) 2022-06-30
BR112018070123A2 (en) 2019-02-05
WO2017173358A1 (en) 2017-10-05
RU2754130C2 (en) 2021-08-27
CN109195604B (en) 2023-11-14
CA3019146A1 (en) 2017-10-05
HRP20220716T1 (en) 2022-09-02
MA44526A (en) 2021-06-02
RU2018138183A (en) 2020-05-12
AU2017240157B2 (en) 2022-10-20
JP2019510051A (en) 2019-04-11
JP7308886B2 (en) 2023-07-14
HUE059491T2 (en) 2022-11-28
CA3019146C (en) 2024-03-26
US20210261598A1 (en) 2021-08-26
SI3436022T1 (en) 2022-08-31
AU2017240157A1 (en) 2018-10-25
CN109195604A (en) 2019-01-11
ES2921010T3 (en) 2022-08-16
EP3436022B1 (en) 2022-03-09
RU2018138183A3 (en) 2020-05-26

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