LT3170896T - Pliuripotentinių kamieninių ląstelių, turinčių antigenui specifinį t ląstelių receptoriaus geną, gavimo būdas - Google Patents
Pliuripotentinių kamieninių ląstelių, turinčių antigenui specifinį t ląstelių receptoriaus geną, gavimo būdasInfo
- Publication number
- LT3170896T LT3170896T LTEP15822874.2T LT15822874T LT3170896T LT 3170896 T LT3170896 T LT 3170896T LT 15822874 T LT15822874 T LT 15822874T LT 3170896 T LT3170896 T LT 3170896T
- Authority
- LT
- Lithuania
- Prior art keywords
- antigen
- specific
- stem cells
- production method
- pluripotent stem
- Prior art date
Links
- 108700042075 T-Cell Receptor Genes Proteins 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 210000001778 pluripotent stem cell Anatomy 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/463—Cellular immunotherapy characterised by recombinant expression
- A61K39/4632—T-cell receptors [TCR]; antibody T-cell receptor constructs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464452—Transcription factors, e.g. SOX or c-MYC
- A61K39/464453—Wilms tumor 1 [WT1]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Oncology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Transplantation (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462026336P | 2014-07-18 | 2014-07-18 | |
PCT/JP2015/070623 WO2016010154A1 (ja) | 2014-07-18 | 2015-07-17 | 抗原特異的t細胞受容体遺伝子を有する多能性幹細胞の製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
LT3170896T true LT3170896T (lt) | 2020-07-10 |
Family
ID=55078639
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP15822874.2T LT3170896T (lt) | 2014-07-18 | 2015-07-17 | Pliuripotentinių kamieninių ląstelių, turinčių antigenui specifinį t ląstelių receptoriaus geną, gavimo būdas |
Country Status (14)
Country | Link |
---|---|
US (1) | US20170304417A1 (lt) |
EP (1) | EP3170896B1 (lt) |
JP (1) | JP6942466B2 (lt) |
CN (1) | CN107002036A (lt) |
AU (1) | AU2015290560B2 (lt) |
CY (1) | CY1122993T1 (lt) |
DK (1) | DK3170896T3 (lt) |
ES (1) | ES2793025T3 (lt) |
HU (1) | HUE049347T2 (lt) |
LT (1) | LT3170896T (lt) |
PL (1) | PL3170896T3 (lt) |
PT (1) | PT3170896T (lt) |
SI (1) | SI3170896T1 (lt) |
WO (1) | WO2016010154A1 (lt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015178431A1 (ja) | 2014-05-21 | 2015-11-26 | 国立大学法人京都大学 | 膵芽細胞の製造方法および膵芽細胞を含む膵疾患治療剤 |
US11834757B2 (en) * | 2017-12-06 | 2023-12-05 | New York Blood Center, Inc. | HLA homozygous induced pluripotent stem cell (iPSC) libraries |
CN112752838A (zh) * | 2018-07-26 | 2021-05-04 | 国立大学法人京都大学 | 制备引入外源抗原受体的细胞的方法 |
JPWO2022059780A1 (lt) * | 2020-09-18 | 2022-03-24 | ||
EP4219707A1 (en) | 2020-09-24 | 2023-08-02 | Kyoto University | Method for producing effector cell having desired specificity |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006306822A (ja) * | 2005-05-02 | 2006-11-09 | Japan Science & Technology Agency | 移植片拒絶反応及び移植片対宿主疾患を防ぐ移植免疫反応抑制ポリフェノール溶液及び移植免疫反応抑制方法 |
US20090217403A1 (en) * | 2005-06-06 | 2009-08-27 | Hergen Spits | Means and methods for generating a t cell against an antigen of interest |
WO2011068962A1 (en) * | 2009-12-03 | 2011-06-09 | The University Of Utah Research Foundation | Methods for generating t lymphocytes from hematopoietic stem cells |
US9206394B2 (en) * | 2010-02-03 | 2015-12-08 | The University Of Tokyo | Method for reconstructing immune function using pluripotent stem cells |
-
2015
- 2015-07-17 LT LTEP15822874.2T patent/LT3170896T/lt unknown
- 2015-07-17 WO PCT/JP2015/070623 patent/WO2016010154A1/ja active Application Filing
- 2015-07-17 ES ES15822874T patent/ES2793025T3/es active Active
- 2015-07-17 AU AU2015290560A patent/AU2015290560B2/en active Active
- 2015-07-17 DK DK15822874.2T patent/DK3170896T3/da active
- 2015-07-17 PT PT158228742T patent/PT3170896T/pt unknown
- 2015-07-17 EP EP15822874.2A patent/EP3170896B1/en active Active
- 2015-07-17 CN CN201580049886.1A patent/CN107002036A/zh active Pending
- 2015-07-17 JP JP2016534511A patent/JP6942466B2/ja active Active
- 2015-07-17 SI SI201531243T patent/SI3170896T1/sl unknown
- 2015-07-17 PL PL15822874T patent/PL3170896T3/pl unknown
- 2015-07-17 HU HUE15822874A patent/HUE049347T2/hu unknown
- 2015-07-17 US US15/326,973 patent/US20170304417A1/en active Pending
-
2020
- 2020-06-10 CY CY20201100529T patent/CY1122993T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CY1122993T1 (el) | 2021-10-29 |
JPWO2016010154A1 (ja) | 2017-04-27 |
JP6942466B2 (ja) | 2021-09-29 |
PT3170896T (pt) | 2020-06-16 |
EP3170896B1 (en) | 2020-03-11 |
EP3170896A4 (en) | 2018-03-21 |
WO2016010154A1 (ja) | 2016-01-21 |
PL3170896T3 (pl) | 2020-11-02 |
ES2793025T3 (es) | 2020-11-12 |
SI3170896T1 (sl) | 2020-08-31 |
CN107002036A (zh) | 2017-08-01 |
DK3170896T3 (da) | 2020-06-08 |
EP3170896A1 (en) | 2017-05-24 |
US20170304417A1 (en) | 2017-10-26 |
HUE049347T2 (hu) | 2020-09-28 |
AU2015290560B2 (en) | 2021-02-18 |
AU2015290560A1 (en) | 2017-03-09 |
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