LT3063293T - Nukleorūgščių kopijų skaičiaus nustatymas, pagrįstas fragmentų skaičiavimais - Google Patents

Nukleorūgščių kopijų skaičiaus nustatymas, pagrįstas fragmentų skaičiavimais

Info

Publication number
LT3063293T
LT3063293T LTEP14793517.5T LT14793517T LT3063293T LT 3063293 T LT3063293 T LT 3063293T LT 14793517 T LT14793517 T LT 14793517T LT 3063293 T LT3063293 T LT 3063293T
Authority
LT
Lithuania
Prior art keywords
estimates
fragment
nucleic acid
copy number
number determination
Prior art date
Application number
LTEP14793517.5T
Other languages
English (en)
Inventor
Andreas Türk
Original Assignee
Lexogen Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lexogen Gmbh filed Critical Lexogen Gmbh
Publication of LT3063293T publication Critical patent/LT3063293T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/20—Sequence assembly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
    • C12Q2535/122—Massive parallel sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2545/00—Reactions characterised by their quantitative nature
    • C12Q2545/10—Reactions characterised by their quantitative nature the purpose being quantitative analysis
    • C12Q2545/114—Reactions characterised by their quantitative nature the purpose being quantitative analysis involving a quantitation step

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
LTEP14793517.5T 2013-10-31 2014-10-31 Nukleorūgščių kopijų skaičiaus nustatymas, pagrįstas fragmentų skaičiavimais LT3063293T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20130191170 EP2868752A1 (en) 2013-10-31 2013-10-31 Nucleic acid copy number determination based on fragment estimates
PCT/EP2014/073463 WO2015063271A1 (en) 2013-10-31 2014-10-31 Nucleic acid copy number determination based on fragment estimates

Publications (1)

Publication Number Publication Date
LT3063293T true LT3063293T (lt) 2018-01-25

Family

ID=49515258

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP14793517.5T LT3063293T (lt) 2013-10-31 2014-10-31 Nukleorūgščių kopijų skaičiaus nustatymas, pagrįstas fragmentų skaičiavimais

Country Status (6)

Country Link
US (1) US20160244827A1 (lt)
EP (2) EP2868752A1 (lt)
DK (1) DK3063293T3 (lt)
LT (1) LT3063293T (lt)
NO (1) NO3063293T3 (lt)
WO (1) WO2015063271A1 (lt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3460071A1 (en) * 2017-09-22 2019-03-27 Lexogen GmbH Estimating pre-pcr fragment numbers from post-pcr frequencies of unique molecular identifiers
US11183270B2 (en) * 2017-12-07 2021-11-23 International Business Machines Corporation Next generation sequencing sorting in time and space complexity using location integers
CN111755066B (zh) * 2019-03-27 2022-10-18 欧蒙医学诊断（中国）有限公司 一种拷贝数变异的检测方法和实施该方法的设备
KR20220097894A (ko) * 2019-10-16 2022-07-08 스틸라 테크놀로지스 핵산 서열 농도의 측정
CN114171121B (zh) * 2020-09-10 2024-05-17 深圳华大生命科学研究院 一种mRNA 5’3’末端差异的快速检测方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090171640A1 (en) 2007-12-28 2009-07-02 Microsoft Corporation Population sequencing using short read technologies
WO2009091798A1 (en) 2008-01-16 2009-07-23 Helicos Biosciences Corporation Quantitative genetic analysis
EP2333104A1 (en) 2009-12-11 2011-06-15 Lexogen GmbH RNA analytics method
KR101295784B1 (ko) 2011-10-31 2013-08-12 삼성에스디에스 주식회사 목표 유전체 서열 내의 신규서열 생성 장치 및 방법

Also Published As

Publication number Publication date
EP3063293B1 (en) 2017-11-15
US20160244827A1 (en) 2016-08-25
EP3063293A1 (en) 2016-09-07
EP2868752A1 (en) 2015-05-06
WO2015063271A1 (en) 2015-05-07
NO3063293T3 (lt) 2018-04-14
DK3063293T3 (en) 2018-02-19

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