LT2979700T - Priešnavikinis agentas, turintis mažą irinotekano hidrochlorido hidrato dozę - Google Patents
Priešnavikinis agentas, turintis mažą irinotekano hidrochlorido hidrato dozęInfo
- Publication number
- LT2979700T LT2979700T LTEP14773638.3T LT14773638T LT2979700T LT 2979700 T LT2979700 T LT 2979700T LT 14773638 T LT14773638 T LT 14773638T LT 2979700 T LT2979700 T LT 2979700T
- Authority
- LT
- Lithuania
- Prior art keywords
- low dose
- antitumor agent
- including low
- agent including
- hydrochloride hydrate
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 229960000779 irinotecan hydrochloride Drugs 0.000 title 1
- GURKHSYORGJETM-WAQYZQTGSA-N irinotecan hydrochloride (anhydrous) Chemical compound Cl.C1=C2C(CC)=C3CN(C(C4=C([C@@](C(=O)OC4)(O)CC)C=4)=O)C=4C3=NC2=CC=C1OC(=O)N(CC1)CCC1N1CCCCC1 GURKHSYORGJETM-WAQYZQTGSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013066074 | 2013-03-27 | ||
| PCT/JP2014/058733 WO2014157444A1 (ja) | 2013-03-27 | 2014-03-27 | 低用量イリノテカン塩酸塩水和物を含有する抗腫瘍剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT2979700T true LT2979700T (lt) | 2018-12-27 |
Family
ID=51624406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP14773638.3T LT2979700T (lt) | 2013-03-27 | 2014-03-27 | Priešnavikinis agentas, turintis mažą irinotekano hidrochlorido hidrato dozę |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9616081B2 (lt) |
| EP (1) | EP2979700B1 (lt) |
| JP (1) | JP6002835B2 (lt) |
| KR (1) | KR101848131B1 (lt) |
| AU (1) | AU2014245147B2 (lt) |
| CY (1) | CY1120990T1 (lt) |
| DK (1) | DK2979700T3 (lt) |
| ES (1) | ES2702911T3 (lt) |
| HR (1) | HRP20182145T1 (lt) |
| HU (1) | HUE041687T2 (lt) |
| LT (1) | LT2979700T (lt) |
| PL (1) | PL2979700T3 (lt) |
| PT (1) | PT2979700T (lt) |
| RS (1) | RS58067B1 (lt) |
| RU (1) | RU2668125C2 (lt) |
| SI (1) | SI2979700T1 (lt) |
| TR (1) | TR201819576T4 (lt) |
| TW (1) | TWI641374B (lt) |
| UA (1) | UA117581C2 (lt) |
| WO (1) | WO2014157444A1 (lt) |
| ZA (1) | ZA201507444B (lt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013202947B2 (en) | 2012-06-13 | 2016-06-02 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan |
| US9717724B2 (en) | 2012-06-13 | 2017-08-01 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies |
| PL2979701T3 (pl) | 2013-03-27 | 2020-12-28 | Taiho Pharmaceutical Co., Ltd. | Środek przeciwnowotworowy obejmujący hydrat chlorowodorku irynotekanu |
| RU2682161C2 (ru) | 2013-09-06 | 2019-03-15 | Тайхо Фармасьютикал Ко., Лтд. | Противоопухолевое средство и усилитель противоопухолевого эффекта |
| US11318131B2 (en) | 2015-05-18 | 2022-05-03 | Ipsen Biopharm Ltd. | Nanoliposomal irinotecan for use in treating small cell lung cancer |
| SI3337467T1 (sl) | 2015-08-20 | 2021-03-31 | Ipsen Biopharm Ltd. Ash Road | Kombinacijska terapija, ki vsebuje liposomski irinotekan in zaviralec PARP za zdravljenje raka |
| EP3791876A1 (en) | 2015-08-21 | 2021-03-17 | Ipsen Biopharm Ltd. | Methods for treating metastatic pancreatic cancer using combination therapies comprising liposomal irinotecan and oxaliplatin |
| SG11201903615WA (en) | 2016-11-02 | 2019-05-30 | Ipsen Biopharm Ltd | Treating gastric cancer using combination therapies comprising liposomal irinotecan, oxaliplatin, 5-fluoruracil (and leucovorin) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6019790A (ja) | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| AU681321B2 (en) | 1995-03-29 | 1997-08-21 | Taiho Pharmaceutical Co., Ltd. | Uracil derivatives, and antitumor effect potentiator and antitumor agent containing the same |
| RU2361592C2 (ru) * | 2004-09-22 | 2009-07-20 | Пфайзер Инк. | Терапевтические комбинации, содержащие ингибитор поли(адф-рибоза)полимеразы |
| PL1839662T3 (pl) * | 2005-01-19 | 2010-08-31 | Zeria Pharm Co Ltd | Środek przeciwnowotworowy |
| US7799783B2 (en) | 2005-01-26 | 2010-09-21 | Taiho Pharmaceutical Co., Ltd. | Method of administrating an anticancer drug containing α, α, α-trifluorothymidine and thymidine phosphorylase inhibitor |
| PT1849470T (pt) | 2005-01-26 | 2017-09-22 | Taiho Pharmaceutical Co Ltd | Fármaco anticancro contendo alfa, alfa, alfa-trifluorotimidina e inibidor da timidina-fosforilase |
| GB0506708D0 (en) * | 2005-04-01 | 2005-05-11 | Queen Mary & Westfield College | Use of calcitonin as combined treatment therapy for the management of inflammatory disease conditions |
| GR20060100144A (el) | 2006-03-03 | 2007-10-17 | Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene | |
| EP2040696B1 (en) * | 2006-07-14 | 2017-01-25 | DSM IP Assets B.V. | Compositions and use thereof for the treatment, co-treatment or prevention of inflammatory disorders |
| JP2011157298A (ja) | 2010-02-01 | 2011-08-18 | Aska Pharmaceutical Co Ltd | 胃潰瘍治療剤 |
-
2014
- 2014-03-27 RS RS20181521A patent/RS58067B1/sr unknown
- 2014-03-27 US US14/779,759 patent/US9616081B2/en active Active
- 2014-03-27 TW TW103111512A patent/TWI641374B/zh active
- 2014-03-27 HU HUE14773638A patent/HUE041687T2/hu unknown
- 2014-03-27 ES ES14773638T patent/ES2702911T3/es active Active
- 2014-03-27 PL PL14773638T patent/PL2979700T3/pl unknown
- 2014-03-27 UA UAA201510465A patent/UA117581C2/uk unknown
- 2014-03-27 AU AU2014245147A patent/AU2014245147B2/en active Active
- 2014-03-27 EP EP14773638.3A patent/EP2979700B1/en active Active
- 2014-03-27 PT PT14773638T patent/PT2979700T/pt unknown
- 2014-03-27 RU RU2015145997A patent/RU2668125C2/ru active
- 2014-03-27 DK DK14773638.3T patent/DK2979700T3/en active
- 2014-03-27 SI SI201430982T patent/SI2979700T1/sl unknown
- 2014-03-27 JP JP2015508649A patent/JP6002835B2/ja active Active
- 2014-03-27 KR KR1020157026552A patent/KR101848131B1/ko active IP Right Grant
- 2014-03-27 TR TR2018/19576T patent/TR201819576T4/tr unknown
- 2014-03-27 LT LTEP14773638.3T patent/LT2979700T/lt unknown
- 2014-03-27 WO PCT/JP2014/058733 patent/WO2014157444A1/ja active Application Filing
-
2015
- 2015-10-07 ZA ZA2015/07444A patent/ZA201507444B/en unknown
-
2018
- 2018-12-18 HR HRP20182145TT patent/HRP20182145T1/hr unknown
- 2018-12-18 CY CY181101357T patent/CY1120990T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUE041687T2 (hu) | 2019-05-28 |
| PL2979700T3 (pl) | 2019-03-29 |
| EP2979700B1 (en) | 2018-09-26 |
| ZA201507444B (en) | 2017-01-25 |
| TW201513864A (zh) | 2015-04-16 |
| KR101848131B1 (ko) | 2018-04-11 |
| RS58067B1 (sr) | 2019-02-28 |
| KR20150136074A (ko) | 2015-12-04 |
| TWI641374B (zh) | 2018-11-21 |
| WO2014157444A1 (ja) | 2014-10-02 |
| TR201819576T4 (tr) | 2019-01-21 |
| US20160082031A1 (en) | 2016-03-24 |
| JP6002835B2 (ja) | 2016-10-05 |
| CY1120990T1 (el) | 2019-12-11 |
| ES2702911T3 (es) | 2019-03-06 |
| AU2014245147A1 (en) | 2015-10-15 |
| AU2014245147B2 (en) | 2017-08-31 |
| PT2979700T (pt) | 2018-12-27 |
| EP2979700A4 (en) | 2016-11-23 |
| UA117581C2 (uk) | 2018-08-27 |
| RU2668125C2 (ru) | 2018-09-26 |
| JPWO2014157444A1 (ja) | 2017-02-16 |
| DK2979700T3 (en) | 2019-01-21 |
| SI2979700T1 (sl) | 2019-01-31 |
| EP2979700A1 (en) | 2016-02-03 |
| US9616081B2 (en) | 2017-04-11 |
| RU2015145997A (ru) | 2017-05-04 |
| HRP20182145T1 (hr) | 2019-03-08 |
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