LT2892920T - Inhibitoriniai peptidai, gauti iš mieloidinių ląstelių ekspresuojamo aktyvinančio receptoriaus-1 (trem-1) ir trem tipo transkripto-1 (tlt-1), ir jų panaudojimas - Google Patents

Inhibitoriniai peptidai, gauti iš mieloidinių ląstelių ekspresuojamo aktyvinančio receptoriaus-1 (trem-1) ir trem tipo transkripto-1 (tlt-1), ir jų panaudojimas

Info

Publication number
LT2892920T
LT2892920T LTEP13759234.1T LT13759234T LT2892920T LT 2892920 T LT2892920 T LT 2892920T LT 13759234 T LT13759234 T LT 13759234T LT 2892920 T LT2892920 T LT 2892920T
Authority
LT
Lithuania
Prior art keywords
trem
tlt
transcript
peptides derived
myeloid cells
Prior art date
Application number
LTEP13759234.1T
Other languages
English (en)
Inventor
Sébastien GIBOT
Amir BOUFENZER
Hafid Ait-Oufella
Marc Derive
Original Assignee
INSERM (Institut National de la Santé et de la Recherche Médicale)
Université De Lorraine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INSERM (Institut National de la Santé et de la Recherche Médicale), Université De Lorraine filed Critical INSERM (Institut National de la Santé et de la Recherche Médicale)
Publication of LT2892920T publication Critical patent/LT2892920T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
LTEP13759234.1T 2012-09-07 2013-09-09 Inhibitoriniai peptidai, gauti iš mieloidinių ląstelių ekspresuojamo aktyvinančio receptoriaus-1 (trem-1) ir trem tipo transkripto-1 (tlt-1), ir jų panaudojimas LT2892920T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12306079 2012-09-07
PCT/EP2013/068628 WO2014037565A2 (en) 2012-09-07 2013-09-09 Inhibiting peptides derived from triggering receptor expressed on myeloid cells-1 (trem-1) trem-like transcript 1 (tlt-1) and uses thereof

Publications (1)

Publication Number Publication Date
LT2892920T true LT2892920T (lt) 2020-07-10

Family

ID=46826397

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP13759234.1T LT2892920T (lt) 2012-09-07 2013-09-09 Inhibitoriniai peptidai, gauti iš mieloidinių ląstelių ekspresuojamo aktyvinančio receptoriaus-1 (trem-1) ir trem tipo transkripto-1 (tlt-1), ir jų panaudojimas

Country Status (24)

Country Link
US (1) US9657081B2 (lt)
EP (1) EP2892920B1 (lt)
JP (1) JP6307080B2 (lt)
KR (1) KR102181384B1 (lt)
CN (1) CN104837865B (lt)
AU (1) AU2013311606B2 (lt)
CA (1) CA2884121C (lt)
CY (1) CY1123014T1 (lt)
DK (1) DK2892920T3 (lt)
ES (1) ES2797625T3 (lt)
HK (1) HK1212360A1 (lt)
HR (1) HRP20200875T8 (lt)
HU (1) HUE051557T2 (lt)
IL (1) IL237615B (lt)
LT (1) LT2892920T (lt)
MX (1) MX2015002994A (lt)
NZ (1) NZ705899A (lt)
PL (1) PL2892920T3 (lt)
PT (1) PT2892920T (lt)
RS (1) RS60421B1 (lt)
RU (1) RU2672341C2 (lt)
SI (1) SI2892920T1 (lt)
WO (1) WO2014037565A2 (lt)
ZA (1) ZA201501779B (lt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018524299A (ja) * 2015-06-12 2018-08-30 マッカイ メディカル ファンデーション ザ プレスビュテロス チャーチ イン タイワン マッカイ メモリアル ホスピタル 免疫応答を調節するための方法およびポリペプチド
WO2017152102A2 (en) 2016-03-04 2017-09-08 Alector Llc Anti-trem1 antibodies and methods of use thereof
JOP20190248A1 (ar) 2017-04-21 2019-10-20 Amgen Inc بروتينات ربط مولد ضد trem2 واستخداماته
WO2020036987A1 (en) 2018-08-13 2020-02-20 Signablok, Inc. Peptides and compositions for targeted treatment and imaging
WO2021105137A1 (en) 2019-11-25 2021-06-03 INSERM (Institut National de la Santé et de la Recherche Médicale) Trem-1 inhibitors for the treatment of vaso-occlusions and tissue injuries in patients suffering from sickle cell disease
EP4161551A1 (en) * 2020-06-05 2023-04-12 Inotrem Trem-1 inhibitor for use in the treatment of a subject suffering from a coronavirus infection
MX2022016548A (es) 2020-06-26 2023-03-14 Amgen Inc Muteínas de il-10 y proteínas de fusión de las mismas.
WO2022189659A1 (en) 2021-03-12 2022-09-15 INSERM (Institut National de la Santé et de la Recherche Médicale) Trem-1 inhibitors for the treatment of marfan syndrome
EP4359441A1 (en) 2021-06-25 2024-05-01 Amgen Inc. Treatment of cardiovascular disease with trem-1 antigen binding proteins

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861719A (en) 1986-04-25 1989-08-29 Fred Hutchinson Cancer Research Center DNA constructs for retrovirus packaging cell lines
US5278056A (en) 1988-02-05 1994-01-11 The Trustees Of Columbia University In The City Of New York Retroviral packaging cell lines and process of using same
US5670488A (en) 1992-12-03 1997-09-23 Genzyme Corporation Adenovirus vector for gene therapy
DE69434860T2 (de) 1993-02-22 2007-03-15 The Rockefeller University Herstellung von helfer-freien retroviren mit hohem titer mittels transienter transfektion
FR2712812B1 (fr) 1993-11-23 1996-02-09 Centre Nat Rech Scient Composition pour la production de produits thérapeutiques in vivo.
NZ293261A (en) 1994-09-12 1998-11-25 Schering Ag Recombinant pallidipin protein, asp-pallidipin, which inhibits collagen induced platelet aggregation inhibitor
IL116816A (en) 1995-01-20 2003-05-29 Rhone Poulenc Rorer Sa Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
WO2002016416A2 (en) * 2000-08-22 2002-02-28 The Brigham And Women's Hospital, Inc. Diagnosis and treatment of cardiovascular conditions
US20040180409A1 (en) * 2003-03-16 2004-09-16 Mcvicar Daniel TLT-1, a novel platelet-associated receptor and uses therefor
GB0426146D0 (en) * 2004-11-29 2004-12-29 Bioxell Spa Therapeutic peptides and method
US7553936B2 (en) * 2006-12-04 2009-06-30 The United States of America as represented by Secretary Department of Health and Human Services Anti-TREM-like transcript-1 (TLT-1) antibodies and compositions
EP2174131A1 (en) 2007-07-23 2010-04-14 Bioxell S.p.a. Screening, therapy and diagnosis
DE102009018620A1 (de) 2009-04-27 2010-10-28 Carefusion Germany 234 Gmbh Ansteuer- und Auswerteschaltung, Messgerät sowie Verfahren zum Messen der Konzentration eines Gases
JP5467313B2 (ja) * 2009-09-28 2014-04-09 国立大学法人 岡山大学 アテローム動脈硬化抑制剤
CA2795390C (en) * 2010-04-08 2020-11-03 Inserm (Institut National De La Sante Et De La Recherche Medicale) Inhibiting peptides derived from trem-like transcript 1 (tlt-1) and uses thereof

Also Published As

Publication number Publication date
SI2892920T1 (sl) 2020-08-31
WO2014037565A2 (en) 2014-03-13
CN104837865A (zh) 2015-08-12
EP2892920A2 (en) 2015-07-15
JP2015533791A (ja) 2015-11-26
AU2013311606B2 (en) 2017-10-05
CY1123014T1 (el) 2021-10-29
DK2892920T3 (da) 2020-06-08
HUE051557T2 (hu) 2021-03-01
US9657081B2 (en) 2017-05-23
PT2892920T (pt) 2020-06-16
EP2892920B1 (en) 2020-03-04
CN104837865B (zh) 2019-09-24
MX2015002994A (es) 2016-01-14
IL237615A0 (en) 2015-04-30
JP6307080B2 (ja) 2018-04-04
CA2884121C (en) 2021-10-12
ES2797625T3 (es) 2020-12-03
PL2892920T3 (pl) 2020-08-24
CA2884121A1 (en) 2014-03-13
RS60421B1 (sr) 2020-07-31
ZA201501779B (en) 2016-10-26
HK1212360A1 (en) 2016-06-10
KR20150110460A (ko) 2015-10-02
KR102181384B1 (ko) 2020-11-20
WO2014037565A3 (en) 2014-05-15
RU2672341C2 (ru) 2018-11-14
HRP20200875T1 (hr) 2020-09-04
US20150232531A1 (en) 2015-08-20
NZ705899A (en) 2018-08-31
HRP20200875T8 (hr) 2021-04-30
RU2015112625A (ru) 2016-10-27
WO2014037565A9 (en) 2015-06-11
AU2013311606A1 (en) 2015-04-09
IL237615B (en) 2018-12-31

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