LT2061803T - Fc turinčių baltymų gryninimo būdas - Google Patents
Fc turinčių baltymų gryninimo būdasInfo
- Publication number
- LT2061803T LT2061803T LT07802925T LT07802925T LT2061803T LT 2061803 T LT2061803 T LT 2061803T LT 07802925 T LT07802925 T LT 07802925T LT 07802925 T LT07802925 T LT 07802925T LT 2061803 T LT2061803 T LT 2061803T
- Authority
- LT
- Lithuania
- Prior art keywords
- purification
- containing proteins
- proteins
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06119611 | 2006-08-28 | ||
US84254206P | 2006-09-06 | 2006-09-06 | |
PCT/EP2007/058887 WO2008025748A1 (en) | 2006-08-28 | 2007-08-27 | Process for the purification of fc-containing proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
LT2061803T true LT2061803T (lt) | 2019-11-25 |
Family
ID=38610939
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LT07802925T LT2061803T (lt) | 2006-08-28 | 2007-08-27 | Fc turinčių baltymų gryninimo būdas |
Country Status (21)
Country | Link |
---|---|
US (1) | US8513393B2 (lt) |
EP (1) | EP2061803B2 (lt) |
JP (1) | JP2010501623A (lt) |
KR (1) | KR101770312B1 (lt) |
AR (1) | AR062570A1 (lt) |
AU (1) | AU2007291283B2 (lt) |
CA (1) | CA2661748C (lt) |
DK (1) | DK2061803T4 (lt) |
EA (1) | EA017152B1 (lt) |
ES (1) | ES2755386T5 (lt) |
FI (1) | FI2061803T4 (lt) |
HK (1) | HK1131400A1 (lt) |
HU (1) | HUE045898T2 (lt) |
IL (1) | IL197220A (lt) |
LT (1) | LT2061803T (lt) |
MX (1) | MX2009002014A (lt) |
PL (1) | PL2061803T5 (lt) |
PT (1) | PT2061803T (lt) |
SI (1) | SI2061803T2 (lt) |
UA (1) | UA99262C2 (lt) |
WO (1) | WO2008025748A1 (lt) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10508144B2 (en) | 2005-12-20 | 2019-12-17 | Bristol-Myers Squibb Company | Carbohydrate content of CTLA4 molecules |
AR058568A1 (es) | 2005-12-20 | 2008-02-13 | Bristol Myers Squibb Co | Metodos para producir una composicion con moleculas ctla4-ig a partir de un medio de cultivo |
SI2061803T2 (sl) † | 2006-08-28 | 2023-01-31 | Ares Trading S.A. | Postopek za čiščenje proteinov, ki vsebujejo FC |
PE20091434A1 (es) * | 2007-10-30 | 2009-10-17 | Genentech Inc | Purificacion de anticuerpos por cromatografia de intercambio cationico |
SG195574A1 (en) * | 2008-10-20 | 2013-12-30 | Abbott Lab | Antibodies that bind to il-18 and methods of purifying the same |
BRPI0920572A8 (pt) * | 2008-10-20 | 2015-10-27 | Abbott Lab | Inativação viral durante a purificação dos anticorpos |
TW201024319A (en) * | 2008-10-20 | 2010-07-01 | Abbott Lab | Antibodies that bind to IL-12 and methods of purifying the same |
EP2350127B1 (en) | 2008-10-20 | 2015-01-28 | AbbVie Inc. | Isolation and purification of antibodies using protein a affinity chromatography |
IN2012DN00338A (lt) * | 2009-08-07 | 2015-05-22 | Millipore Corp | |
LT2513134T (lt) | 2009-12-18 | 2017-11-27 | Novartis Ag | Praplovimo tirpalas ir afininės chromatografijos metodas |
JP5773454B2 (ja) | 2010-01-15 | 2015-09-02 | バイオ−ラッド ラボラトリーズ インコーポレーティッド | アパタイトの表面中和方法 |
US8895707B2 (en) * | 2010-08-18 | 2014-11-25 | Bio-Rad Laboratories, Inc. | Elution of proteins from hydroxyapatite resins without resin deterioration |
JP5798307B2 (ja) * | 2010-09-03 | 2015-10-21 | 国立大学法人名古屋大学 | グロボトリアオシルセラミドを特異的に認識するモノクローナル抗体及びその作製法 |
JP5838221B2 (ja) | 2010-12-21 | 2016-01-06 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | アイソフォーム濃縮抗体調製物及びこれを得る方法 |
CA2825651C (en) | 2011-02-02 | 2020-03-24 | Bio-Rad Laboratories, Inc. | Apatite surface neutralization with alkali solutions |
BR112013024933A2 (pt) | 2011-03-29 | 2016-09-06 | Glaxosmithkline Llc | sistema tampão para purificação de proteínas |
SG10201701224UA (en) * | 2012-03-12 | 2017-04-27 | Merck Patent Gmbh | Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode |
US9815695B2 (en) | 2012-05-30 | 2017-11-14 | Bio-Rad Laboratories, Inc. | In situ restoration of apatite-based chromatography resins |
EP2682168A1 (en) | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
EP3155009A1 (en) * | 2014-06-13 | 2017-04-19 | Lupin Limited | Process for the purification of tnfr:fc fusion protein |
US10092857B2 (en) | 2014-06-23 | 2018-10-09 | Bio-Rad Laboratories, Inc. | Apatite in-situ restoration |
CN105392569B (zh) | 2014-06-23 | 2019-08-20 | 生物辐射实验室股份有限公司 | 磷灰石预处理 |
EP2975050B1 (en) * | 2014-07-18 | 2019-05-29 | Sandoz Ag | Quantification of misfolded TNFR2:Fc |
WO2016149088A1 (en) * | 2015-03-13 | 2016-09-22 | Bristol-Myers Squibb Company | Use of alkaline washes during chromatography to remove impurities |
CN116903727A (zh) | 2020-05-08 | 2023-10-20 | 高山免疫科学股份有限公司 | 具有和不具有t细胞抑制蛋白的april和baff抑制性免疫调节蛋白及其使用方法 |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2065346C (en) | 1989-09-05 | 2005-03-29 | Craig A. Smith | Tumor necrosis factor-.alpha. and-.beta. receptors |
US5447851B1 (en) * | 1992-04-02 | 1999-07-06 | Univ Texas System Board Of | Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells |
NZ256293A (en) | 1992-09-15 | 1997-06-24 | Immunex Corp | Method of treating tumour necrosis factor - mediated inflammation by use of tnf antagonist |
DK0659767T4 (da) * | 1993-12-27 | 2003-02-10 | Zlb Bioplasma Ag | Fremgangsmåde til fremstilling af et koncentrat af anti-D-immunoglobulin G og et farmaceutisk præparat, som indeholder dette |
AU712759C (en) * | 1995-06-08 | 2001-08-09 | Immunex Corporation | TNF-alpha converting enzyme |
US6406901B1 (en) * | 1995-06-08 | 2002-06-18 | Immunex Corporation | TNF-a converting enzyme |
US5969102A (en) | 1997-03-03 | 1999-10-19 | St. Jude Children's Research Hospital | Lymphocyte surface receptor that binds CAML, nucleic acids encoding the same and methods of use thereof |
IL121900A (en) | 1997-10-07 | 2001-12-23 | Omrix Biopharmaceuticals Ltd | A method for the purification of immunoglobulins |
IL139035A0 (en) | 1998-05-06 | 2001-11-25 | Genentech Inc | Protein purification by ion exchange chromatography |
PT1084136E (pt) | 1998-06-01 | 2004-12-31 | Genentech Inc | Separacao de monomeros de anticorpos dos seus multimeros atraves da utilizacao de cromatografia de troca ionica |
PT1084147E (pt) | 1998-06-09 | 2005-01-31 | Statens Seruminstitut | Processo para producao de imunoglobulinas para administracao intravenosa e outros produtos de imunoglobulina |
PL393286A1 (pl) | 1999-01-07 | 2011-06-06 | Zymogenetics, Inc. | Rozpuszczalny receptor BR43x2 i sposoby jego zastosowania |
DE19955558C2 (de) | 1999-11-18 | 2003-03-20 | Stefan Kochanek | Permanente Amniozyten-Zelllinie, ihre Herstellung und Verwendung zur Herstellung von Gentransfervektoren |
WO2001087977A2 (en) * | 2000-05-12 | 2001-11-22 | Amgen Inc. | Methods and compositions of matter concerning april/g70, bcma, blys/agp-3, and taci |
PL403488A1 (pl) * | 2001-05-24 | 2013-07-08 | Zymogenetics, Inc. | Zastosowanie bialka fuzyjnego TACI-immunoglobulina, bialko fuzyjne, czasteczka kwasu nukleinowego kodujaca bialko fuzyjne, kompozycja farmaceutyczna i sposób wytwarzania bialka fuzyjnego TACI-immunoglobulina |
NZ547695A (en) | 2001-06-26 | 2008-09-26 | Amgen Fremont Inc | Antibodies to OPGL |
ES2322945T5 (es) | 2001-12-21 | 2012-10-17 | Immunex Corporation | Métodos para purficación de proteína |
US20060234226A1 (en) * | 2002-04-26 | 2006-10-19 | Fahner Robert L | Non-affinity purification of proteins |
JP5525118B2 (ja) | 2002-09-11 | 2014-06-18 | 中外製薬株式会社 | タンパク質精製方法 |
ES2527616T3 (es) | 2002-09-11 | 2015-01-27 | Genentech, Inc. | Purificación de anticuerpos anti-HER2 |
DK1601697T3 (da) * | 2003-02-28 | 2007-10-01 | Lonza Biologics Plc | Oprensning af antistof ved protein A- og ionbytningskromatografi |
JPWO2004087761A1 (ja) * | 2003-03-31 | 2006-07-27 | 麒麟麦酒株式会社 | ヒトモノクローナル抗体およびヒトポリクローナル抗体の精製 |
TWI353991B (en) * | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
EP1678208B1 (en) * | 2003-10-27 | 2013-05-15 | Wyeth LLC | Removal of high molecular weight aggregates using hydroxyapatite chromatography |
PL2256134T3 (pl) * | 2003-11-13 | 2014-06-30 | Hanmi Science Co Ltd | Fragment Fc Ig do nośnika leku i sposób jego wytwarzania |
CN1946739A (zh) * | 2004-04-14 | 2007-04-11 | 豪夫迈-罗氏公司 | 纯化的白细胞介素-15/Fc融合蛋白及其制备 |
RU2457214C2 (ru) | 2005-03-11 | 2012-07-27 | Вайет | Способ хроматографии в режиме слабого распределения |
CA2604877A1 (en) * | 2005-04-11 | 2006-10-19 | J.P. Sercel Associates Inc. | Protein purification |
WO2006138553A2 (en) * | 2005-06-17 | 2006-12-28 | Wyeth | Methods of purifying fc region containing proteins |
WO2009017491A1 (en) | 2006-06-14 | 2009-02-05 | Smithkline Beecham Corporation | Methods for purifying antibodies using ceramic hydroxyapatite |
SI2061803T2 (sl) † | 2006-08-28 | 2023-01-31 | Ares Trading S.A. | Postopek za čiščenje proteinov, ki vsebujejo FC |
WO2008087184A2 (en) * | 2007-01-17 | 2008-07-24 | Merck Serono S.A. | Process for the purification of fc-containing proteins |
-
2007
- 2007-08-27 SI SI200732135T patent/SI2061803T2/sl unknown
- 2007-08-27 ES ES07802925T patent/ES2755386T5/es active Active
- 2007-08-27 JP JP2009526068A patent/JP2010501623A/ja active Pending
- 2007-08-27 HU HUE07802925A patent/HUE045898T2/hu unknown
- 2007-08-27 PL PL07802925.3T patent/PL2061803T5/pl unknown
- 2007-08-27 MX MX2009002014A patent/MX2009002014A/es active IP Right Grant
- 2007-08-27 PT PT78029253T patent/PT2061803T/pt unknown
- 2007-08-27 FI FIEP07802925.3T patent/FI2061803T4/fi active
- 2007-08-27 AU AU2007291283A patent/AU2007291283B2/en active Active
- 2007-08-27 US US12/377,122 patent/US8513393B2/en active Active
- 2007-08-27 UA UAA200902854A patent/UA99262C2/uk unknown
- 2007-08-27 EA EA200970231A patent/EA017152B1/ru not_active IP Right Cessation
- 2007-08-27 CA CA2661748A patent/CA2661748C/en active Active
- 2007-08-27 EP EP07802925.3A patent/EP2061803B2/en active Active
- 2007-08-27 LT LT07802925T patent/LT2061803T/lt unknown
- 2007-08-27 WO PCT/EP2007/058887 patent/WO2008025748A1/en active Application Filing
- 2007-08-27 KR KR1020097006443A patent/KR101770312B1/ko active IP Right Grant
- 2007-08-27 DK DK07802925.3T patent/DK2061803T4/da active
- 2007-08-28 AR ARP070103817A patent/AR062570A1/es not_active Application Discontinuation
-
2009
- 2009-02-24 IL IL197220A patent/IL197220A/en active IP Right Grant
- 2009-12-03 HK HK09111377.1A patent/HK1131400A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AR062570A1 (es) | 2008-11-19 |
PL2061803T3 (pl) | 2020-02-28 |
EA017152B1 (ru) | 2012-10-30 |
PL2061803T5 (pl) | 2023-03-27 |
ES2755386T3 (es) | 2020-04-22 |
DK2061803T3 (da) | 2019-11-18 |
EP2061803B2 (en) | 2022-11-16 |
AU2007291283A1 (en) | 2008-03-06 |
US8513393B2 (en) | 2013-08-20 |
EP2061803A1 (en) | 2009-05-27 |
FI2061803T4 (fi) | 2023-03-14 |
MX2009002014A (es) | 2009-03-09 |
AU2007291283B2 (en) | 2012-09-20 |
DK2061803T4 (da) | 2022-12-05 |
UA99262C2 (uk) | 2012-08-10 |
IL197220A (en) | 2013-06-27 |
CA2661748C (en) | 2016-02-09 |
SI2061803T2 (sl) | 2023-01-31 |
EP2061803B1 (en) | 2019-08-14 |
PT2061803T (pt) | 2019-11-21 |
WO2008025748A1 (en) | 2008-03-06 |
EA200970231A1 (ru) | 2009-08-28 |
HUE045898T2 (hu) | 2020-01-28 |
KR101770312B1 (ko) | 2017-08-22 |
US20100190961A1 (en) | 2010-07-29 |
KR20090057296A (ko) | 2009-06-04 |
HK1131400A1 (en) | 2010-01-22 |
JP2010501623A (ja) | 2010-01-21 |
ES2755386T5 (es) | 2023-04-05 |
IL197220A0 (en) | 2009-12-24 |
SI2061803T1 (sl) | 2019-12-31 |
CA2661748A1 (en) | 2008-03-06 |
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