KR970027051A - 카바모일기를 포함하는 신규한 설파메이트 화합물 - Google Patents

카바모일기를 포함하는 신규한 설파메이트 화합물 Download PDF

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Publication number
KR970027051A
KR970027051A KR1019950039456A KR19950039456A KR970027051A KR 970027051 A KR970027051 A KR 970027051A KR 1019950039456 A KR1019950039456 A KR 1019950039456A KR 19950039456 A KR19950039456 A KR 19950039456A KR 970027051 A KR970027051 A KR 970027051A
Authority
KR
South Korea
Prior art keywords
compounds containing
carbamoyl groups
phenyl
propanediol
sulfamate compounds
Prior art date
Application number
KR1019950039456A
Other languages
English (en)
Inventor
최용문
한동일
김형철
Original Assignee
조규향
주식회사 유 공
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 조규향, 주식회사 유 공 filed Critical 조규향
Priority to KR1019950039456A priority Critical patent/KR970027051A/ko
Priority to US08/616,077 priority patent/US5654461A/en
Priority to PCT/KR1996/000041 priority patent/WO1997016417A1/en
Priority to KR1019960049052A priority patent/KR100446104B1/ko
Priority to JP51723597A priority patent/JP4094057B2/ja
Priority to PT96935567T priority patent/PT801642E/pt
Priority to ES96935567T priority patent/ES2154840T3/es
Priority to CN96191830A priority patent/CN1077570C/zh
Priority to EP96935567A priority patent/EP0801642B1/en
Priority to CA002209229A priority patent/CA2209229C/en
Priority to DE69611286T priority patent/DE69611286T2/de
Priority to US08/742,929 priority patent/US5892088A/en
Priority to PCT/KR1996/000190 priority patent/WO1997016418A1/en
Priority to DK96935567T priority patent/DK0801642T3/da
Publication of KR970027051A publication Critical patent/KR970027051A/ko
Priority to GR20010400461T priority patent/GR3035615T3/el

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/02—Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

본 발명은 2-페닐-1, 3-프로판디올 단일 카바메이트로부터 유도되는 썰파메이트 화합물들에 관한 것으로서, 좀더 상세하게는 3-카바모일-2-페닐-1, 3-프로판디올 썰파메이트 라세미체 및 이것의 (S)- 및 (R)- 광학이성질체 3종에 관한 것이다.
본 발명에 따른 화합물들은 중추신경계 질병, 예를 들어 신경성 근육통, 간질 및 뇌졸증의 치료 및 예방에 유용하다.

Description

카바모일기를 포함하는 신규한 설파메이트 화합물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (3)

  1. 하기 일반식(Ⅰ)로 표시되는 3-카바모일-2-페닐-1, 3-프로판디올 썰파메이트.
  2. 하기 일반식(Ⅱ)로 표시되는 (R)-3-카바모일-2-페닐-1, 3-프로판디올 썰파메이트.
  3. 하기 일반식(Ⅲ)로 표시되는 (S)-3-카바모일-2-페닐-1, 3-프로판디올 썰파메이트.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950039456A 1995-11-02 1995-11-02 카바모일기를 포함하는 신규한 설파메이트 화합물 KR970027051A (ko)

Priority Applications (15)

Application Number Priority Date Filing Date Title
KR1019950039456A KR970027051A (ko) 1995-11-02 1995-11-02 카바모일기를 포함하는 신규한 설파메이트 화합물
US08/616,077 US5654461A (en) 1995-11-02 1996-03-14 Sulfamate compound containing carbamoyl group
PCT/KR1996/000041 WO1997016417A1 (en) 1995-11-02 1996-03-27 Novel sulfamate compound containing carbamoyl group
KR1019960049052A KR100446104B1 (ko) 1995-11-02 1996-10-28 N-치환된카바모일기를포함하는신규한썰파메이트화합물과이의제조방법
CN96191830A CN1077570C (zh) 1995-11-02 1996-11-01 新颖的含n－取代氨基甲酰基的氨基磺酸酯化合物及其制备
PT96935567T PT801642E (pt) 1995-11-02 1996-11-01 Novo composto sulfamato com um grupo carbamoilo n-substituido e metodo para a sua preparacao
ES96935567T ES2154840T3 (es) 1995-11-02 1996-11-01 Nuevo compuesto de sulfamato que contiene un grupo carbamoilo sustituido en n y metodo para prepararlo.
JP51723597A JP4094057B2 (ja) 1995-11-02 1996-11-01 Ｎ−置換カルバモイル基を含有する新規のスルファメート化合物とその製造方法
EP96935567A EP0801642B1 (en) 1995-11-02 1996-11-01 Novel sulfamate compound containing n-substituted carbamoyl group and method for preparing the same
CA002209229A CA2209229C (en) 1995-11-02 1996-11-01 Novel sulfamate compound containing n-substituted carbamoyl group and method for preparing the same
DE69611286T DE69611286T2 (de) 1995-11-02 1996-11-01 Neue sulfamate mit n-substituierten carbamoyl-gruppen und verfahren zu deren herstellung
US08/742,929 US5892088A (en) 1995-11-02 1996-11-01 Sulfamate compound containing N-substituted carbamoyl group and method for preparing the same
PCT/KR1996/000190 WO1997016418A1 (en) 1995-11-02 1996-11-01 Novel sulfamate compound containing n-substituted carbamoyl group and method for preparing the same
DK96935567T DK0801642T3 (da) 1995-11-02 1996-11-01 Hidtil ukendt sulfamatforbindelse indeholdende N-substitueret carbomoylgruppe og fremgangsmåde til fremstilling af samme
GR20010400461T GR3035615T3 (en) 1995-11-02 2001-03-21 Novel sulfamate compound containing n-substituted carbamoyl group and method for preparing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019950039456A KR970027051A (ko) 1995-11-02 1995-11-02 카바모일기를 포함하는 신규한 설파메이트 화합물

Publications (1)

Publication Number Publication Date
KR970027051A true KR970027051A (ko) 1997-06-24

Family

ID=19432801

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019950039456A KR970027051A (ko) 1995-11-02 1995-11-02 카바모일기를 포함하는 신규한 설파메이트 화합물
KR1019960049052A KR100446104B1 (ko) 1995-11-02 1996-10-28 N-치환된카바모일기를포함하는신규한썰파메이트화합물과이의제조방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019960049052A KR100446104B1 (ko) 1995-11-02 1996-10-28 N-치환된카바모일기를포함하는신규한썰파메이트화합물과이의제조방법

Country Status (3)

Country Link
US (1) US5654461A (ko)
KR (2) KR970027051A (ko)
WO (1) WO1997016417A1 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5892088A (en) * 1995-11-02 1999-04-06 Yukong Limited Sulfamate compound containing N-substituted carbamoyl group and method for preparing the same
DE60142632D1 (de) * 2000-11-30 2010-09-02 Novodermix Internat Ltd Heilung von wunden
AU2003297639A1 (en) * 2002-12-02 2004-06-23 University Of Florida Treatments for benign tumors, cancers, neoplasias, and/or other inflammatory disorders or diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2364876A1 (de) * 1973-12-28 1975-07-03 Basf Ag Butinylcarbamate
CA1082194A (en) * 1974-12-30 1980-07-22 Allen F. Hirsch Aliphatic sulfamates
US4513006A (en) * 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives
US4792569A (en) * 1987-08-27 1988-12-20 Mcneilab, Inc. Anticonvulsant phenethyl sulfamates
US5258402A (en) * 1992-06-11 1993-11-02 Mcneil-Ppc, Inc. Imidate derivatives of pharmaceutically useful anticonvulsant sulfamates
US5384327A (en) * 1992-12-22 1995-01-24 Mcneilab, Inc. Anticonvulsant sorbopyranose sulfamates
US5510379A (en) * 1994-12-19 1996-04-23 Warner-Lambert Company Sulfonate ACAT inhibitors
US5998380A (en) * 1995-10-13 1999-12-07 New England Medical Center Hospitals, Inc. Treatment of migraine

Also Published As

Publication number Publication date
WO1997016417A1 (en) 1997-05-09
KR100446104B1 (ko) 2004-12-08
KR19990068856A (ko) 1999-09-06
US5654461A (en) 1997-08-05

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