KR970021068A - New antibiotic MR-93A and preparation method thereof - Google Patents

New antibiotic MR-93A and preparation method thereof Download PDF

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Publication number
KR970021068A
KR970021068A KR1019950037864A KR19950037864A KR970021068A KR 970021068 A KR970021068 A KR 970021068A KR 1019950037864 A KR1019950037864 A KR 1019950037864A KR 19950037864 A KR19950037864 A KR 19950037864A KR 970021068 A KR970021068 A KR 970021068A
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KR
South Korea
Prior art keywords
strain
antibiotic
preparation
new antibiotic
oxazole
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KR1019950037864A
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Korean (ko)
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KR0154492B1 (en
Inventor
고영희
이충환
정명철
이호재
Original Assignee
김은영
한국과학기술연구원
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Priority to KR1019950037864A priority Critical patent/KR0154492B1/en
Publication of KR970021068A publication Critical patent/KR970021068A/en
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Publication of KR0154492B1 publication Critical patent/KR0154492B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/14—Nitrogen or oxygen as hetero atom and at least one other diverse hetero ring atom in the same ring

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

본 발명은 하기 구조식을 갖는 옥사졸계 신규 항생물질 MR-93A 화합물, 이를 생산하는 트리코데르마(Trichoderma)속 MR93 균주 및 상기 균주를 배양하는 것을 특징으로 하는 신규 항생물질 MR-93A의 제조방법에 관한 것이다.The present invention relates to an oxazole-based novel antibiotic MR-93A compound having the following structural formula, a Trichoderma genus MR93 strain which produces the same, and a method for producing a novel antibiotic MR-93A, comprising culturing the strain. will be.

Description

신규 항생물질 MR-93A 및 이의 제조방법New antibiotic MR-93A and preparation method thereof

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

제1도는 MR-93A 화합물의 수소 핵자기 공명(1H-NMR) 스펙트럼을 나타낸 것이고,Figure 1 shows the hydrogen nuclear magnetic resonance ( 1 H-NMR) spectrum of the MR-93A compound,

제2도는 MR-93A 화합물의 탄소 핵자기 공명(13C-NMR) 스펙트럼을 나타낸 것이다.2 shows the carbon nuclear magnetic resonance ( 13 C-NMR) spectrum of the MR-93A compound.

Claims (4)

하기 구조식을 갖는 옥사졸계 항생물질 MR-93A, 그와 유도체 및 화학적, 약학적으로 허용가능한 염 :Oxazole antibiotic MR-93A, its derivatives, and chemically and pharmaceutically acceptable salts having the formula: 신규 항생물질 MR-93A를 생산한 수 있는 트리코데르마(Trichoderma)속 균주.Trichoderma sp. Strain capable of producing the novel antibiotic MR-93A. 제2항에 있어서, 트리코데르마(Trichoderma)속 MR93 균주인 KCTC 0114BP.3. KCTC 0114BP according to claim 2, which is a Trichoderma genus MR93 strain. 제2항의 균주를 배양하는 것을 특징으로 하는 옥사졸계 항생물질 MR-93A의 생산방법.Method for producing an oxazole-based antibiotic MR-93A characterized by culturing the strain of claim 2. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019950037864A 1995-10-28 1995-10-28 Novel antibiotics mr-93a and process for the preparation thereof KR0154492B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019950037864A KR0154492B1 (en) 1995-10-28 1995-10-28 Novel antibiotics mr-93a and process for the preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019950037864A KR0154492B1 (en) 1995-10-28 1995-10-28 Novel antibiotics mr-93a and process for the preparation thereof

Publications (2)

Publication Number Publication Date
KR970021068A true KR970021068A (en) 1997-05-28
KR0154492B1 KR0154492B1 (en) 1998-11-16

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950037864A KR0154492B1 (en) 1995-10-28 1995-10-28 Novel antibiotics mr-93a and process for the preparation thereof

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KR0154492B1 (en) 1998-11-16

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