KR970009793A - Soft capsule containing ibuprofen solution - Google Patents

Soft capsule containing ibuprofen solution Download PDF

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Publication number
KR970009793A
KR970009793A KR1019950025094A KR19950025094A KR970009793A KR 970009793 A KR970009793 A KR 970009793A KR 1019950025094 A KR1019950025094 A KR 1019950025094A KR 19950025094 A KR19950025094 A KR 19950025094A KR 970009793 A KR970009793 A KR 970009793A
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KR
South Korea
Prior art keywords
weight
soft capsule
acid ester
fatty acid
capsule containing
Prior art date
Application number
KR1019950025094A
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Korean (ko)
Inventor
김태원
김종대
Original Assignee
양주환
주식회사 서흥캅셀
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Application filed by 양주환, 주식회사 서흥캅셀 filed Critical 양주환
Priority to KR1019950025094A priority Critical patent/KR970009793A/en
Publication of KR970009793A publication Critical patent/KR970009793A/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

본 발명은 내용액 전체 중량대비 20∼60중량%의 폴리옥시에틸렌소르비탄지방산에스테르와 5∼40중량%의 폴리글리세린지방산에스테르를 혼합한 다음 1∼10중량%의 폴리비닐피롤리돈과 1∼10중량%의 정제수를 투입하고 가온하여 약 80℃의 온도에서 혼합, 용해하고, 냉각하여 약 60℃에서 25∼40중량%의 이부프로펜을 투입용해시켜 연질캅셀의 내용액을 제조하고, 피막함을 특징으로 하는 이부프로펜 용액을 함유한 연질캅셀제의 제조방법에 관한 것이다.The present invention is a mixture of 20 to 60% by weight of polyoxyethylene sorbitan fatty acid ester with 5 to 40% by weight of polyglycerol fatty acid ester, and then 1 to 10% by weight of polyvinylpyrrolidone with respect to the total weight of the solution 10% by weight of purified water was added, warmed, mixed, dissolved, and cooled at a temperature of about 80 ° C., 25-40% by weight of ibuprofen was dissolved at about 60 ° C. to prepare a solution of the soft capsule. The manufacturing method of the soft capsule containing the ibuprofen solution characterized by the above-mentioned.

Description

이부프로펜 용액을 함유한 연질캅셀제Soft capsule containing ibuprofen solution

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (6)

내용액 전체 중량대비 20∼60중량%의 폴리옥시에틸렌소르비탄지방산에스테르와 5∼40중량%의 폴리글리세린지방산에스테르를 혼합한 다음 1∼10중량%의 폴리비닐피롤리돈과 1∼10중량%의 정제수를 투입하고 가온하여 약 80℃의 온도에서 혼합, 용해하고, 냉각하여 약 60℃에서 25∼40중량%의 이부프로펜을 투입 용해시켜 연질캅셀의 내용액을 제조하고, 피막함을 특징으로 하는 이부프로펜 용액을 함유한 연질캅셀제의 제조방법.20 to 60% by weight of polyoxyethylene sorbitan fatty acid ester and 5 to 40% by weight of polyglycerol fatty acid ester are mixed, and then 1 to 10% by weight of polyvinylpyrrolidone and 1 to 10% by weight Purified water was added, heated, mixed and dissolved at a temperature of about 80 ° C., cooled, and 25-40% by weight of ibuprofen was dissolved at about 60 ° C. to prepare a solution of a soft capsule, characterized in that A method for producing a soft capsule containing an ibuprofen solution. 제1항에 있어서, 폴리옥시에틸렌소르비탄지방산에스테르는 폴리소르베이트 80을 사용함을 특징으로 하는 이부프로펜 용액을 함유한 연질캅셀제의 제조방법.The method for producing a soft capsule containing ibuprofen solution according to claim 1, wherein the polyoxyethylene sorbitan fatty acid ester uses polysorbate 80. 제1항에 있어서, 폴리글리세린지방산에스테르는 폴리글리세린축합리시놀레인산에스테르를 사용함을 특징으로 하는 이부프로펜 용액을 함유한 연질캅셀제의 제조방법.The method for preparing a soft capsule containing ibuprofen solution according to claim 1, wherein the polyglycerol fatty acid ester is a polyglycerol condensed ricinoleic acid ester. 제2항에 있어서, 폴리옥시에틸렌소르비탄지방산에스테르는 내용액 전체 중량대비 30∼50중량% 사용함을 특징으로 하는 이부프로펜 용액을 함유한 연질캅셀제의 제조방법.3. The method of claim 2, wherein the polyoxyethylene sorbitan fatty acid ester is used in an amount of 30 to 50% by weight based on the total weight of the contents. 제3항에 있어서, 폴리글리세린지방산에스테르는 내용액 전체 중량대비 10∼30중량% 사용함을 특징으로 하는 이부프로펜 용액을 함유한 연질캅셀제의 제조방법.4. The method of claim 3, wherein the polyglycerol fatty acid ester is used in an amount of 10 to 30% by weight based on the total weight of the contents. 제1항의 방법에 따라 제조된 이부프로펜 용액을 함유한 연질캅셀제.A soft capsule containing an ibuprofen solution prepared according to the method of claim 1. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019950025094A 1995-08-16 1995-08-16 Soft capsule containing ibuprofen solution KR970009793A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019950025094A KR970009793A (en) 1995-08-16 1995-08-16 Soft capsule containing ibuprofen solution

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Application Number Priority Date Filing Date Title
KR1019950025094A KR970009793A (en) 1995-08-16 1995-08-16 Soft capsule containing ibuprofen solution

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KR970009793A true KR970009793A (en) 1997-03-27

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KR1019950025094A KR970009793A (en) 1995-08-16 1995-08-16 Soft capsule containing ibuprofen solution

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100449818B1 (en) * 2001-03-02 2004-09-22 최영욱 Soft capsule or injection formulation containg ibuprofen by smedds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100449818B1 (en) * 2001-03-02 2004-09-22 최영욱 Soft capsule or injection formulation containg ibuprofen by smedds

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