KR970000222A - 팩리택셀 유도체의 전구약물 - Google Patents

팩리택셀 유도체의 전구약물

Info

Publication number
KR970000222A
KR970000222A KR1019960019825A KR19960019825A KR970000222A KR 970000222 A KR970000222 A KR 970000222A KR 1019960019825 A KR1019960019825 A KR 1019960019825A KR 19960019825 A KR19960019825 A KR 19960019825A KR 970000222 A KR970000222 A KR 970000222A
Authority
KR
South Korea
Prior art keywords
patricaxel
prodrugs
derivatives
patricaxel derivatives
Prior art date
Application number
KR1019960019825A
Other languages
English (en)
Other versions
KR100375956B1 (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR970000222A publication Critical patent/KR970000222A/ko
Application granted granted Critical
Publication of KR100375956B1 publication Critical patent/KR100375956B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6551—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring
    • C07F9/65512—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
KR1019960019825A 1995-06-06 1996-06-04 팩리택셀유도체의전구약물 KR100375956B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46924795A 1995-06-06 1995-06-06
US469,247 1995-06-06

Publications (2)

Publication Number Publication Date
KR970000222A true KR970000222A (ko) 1997-01-21
KR100375956B1 KR100375956B1 (ko) 2003-04-21

Family

ID=23863053

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960019825A KR100375956B1 (ko) 1995-06-06 1996-06-04 팩리택셀유도체의전구약물

Country Status (23)

Country Link
EP (1) EP0747385B1 (ko)
JP (1) JPH08337589A (ko)
KR (1) KR100375956B1 (ko)
CN (1) CN1066151C (ko)
AR (1) AR002756A1 (ko)
AT (1) ATE222259T1 (ko)
AU (1) AU695959B2 (ko)
CA (1) CA2176191A1 (ko)
CZ (1) CZ291516B6 (ko)
DE (1) DE69622933T2 (ko)
DK (1) DK0747385T3 (ko)
ES (1) ES2181824T3 (ko)
HU (1) HUP9601524A3 (ko)
IL (1) IL118526A (ko)
MX (1) MX9601994A (ko)
NO (1) NO315233B1 (ko)
NZ (1) NZ286723A (ko)
PL (1) PL187883B1 (ko)
PT (1) PT747385E (ko)
RU (1) RU2162082C2 (ko)
SG (1) SG72692A1 (ko)
TW (1) TW354293B (ko)
ZA (1) ZA964261B (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395770B1 (en) * 1995-10-26 2002-05-28 Baker Norton Pharmaceuticals, Inc. Method and compositions for administering taxanes orally to human patients
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
US6515016B2 (en) 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis
RU2205005C2 (ru) * 1997-05-27 2003-05-27 Бейкер Нортон Фармасьютикалз, Инк. Способ и композиции для перорального введения таксанов пациентам
US6204257B1 (en) * 1998-08-07 2001-03-20 Universtiy Of Kansas Water soluble prodrugs of hindered alcohols
AU776511B2 (en) * 1999-02-18 2004-09-09 Baylor University Compositions and methods for use in targeting vascular destruction
US6362172B2 (en) * 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
AR030188A1 (es) 2000-02-02 2003-08-13 Univ Florida State Res Found Compuestos de taxano sustituidos con esteres en el c7; composiciones farmaceuticas que los contienen y proceso para tratar un sujeto mamifero que sufre de una condicion que responde a los taxanos
CN1362958A (zh) 2000-02-02 2002-08-07 佛罗里达州立大学研究基金有限公司 用作抗肿瘤剂的c7碳酸酯取代的紫杉烷
US6916942B2 (en) 2000-02-03 2005-07-12 Bristol-Myers Squibb Company Process for the preparation of C-4 carbonate taxanes
US6750246B1 (en) 2000-02-03 2004-06-15 Bristol-Myers Squibb Company C-4 carbonate taxanes
US7063977B2 (en) 2001-08-21 2006-06-20 Bristol-Myers Squibb Company Enzymatic resolution of t-butyl taxane derivatives
KR20030049023A (ko) * 2001-12-13 2003-06-25 주식회사 코오롱 방사선 감작제용 파클리탁셀 유도체
TW200540164A (en) 2004-03-05 2005-12-16 Univ Florida State Res Found C7 lactyloxy-substituted taxanes
CN105879114A (zh) * 2005-02-18 2016-08-24 阿布拉西斯生物科学公司 用于整合入医疗装置的疏水性改善的药物
JP2016512831A (ja) 2013-03-15 2016-05-09 コンサート ファーマシューティカルズ インコーポレイテッド 重水素化されたパルボシクリブ
WO2015009889A1 (en) 2013-07-18 2015-01-22 Concert Pharmaceuticals, Inc. Deuterated intedanib derivatives and their use for the treatment of proliferative disorders
SG10202112588PA (en) * 2015-11-19 2021-12-30 Biohaven Pharm Holding Co Ltd Amine prodrugs of pharmaceutical compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2111527C (en) * 1992-12-24 2000-07-18 Jerzy Golik Phosphonooxymethyl ethers of taxane derivatives
CA2129288C (en) * 1993-08-17 2000-05-16 Jerzy Golik Phosphonooxymethyl esters of taxane derivatives

Also Published As

Publication number Publication date
ATE222259T1 (de) 2002-08-15
PT747385E (pt) 2002-11-29
TW354293B (en) 1999-03-11
IL118526A (en) 2001-05-20
SG72692A1 (en) 2000-05-23
ES2181824T3 (es) 2003-03-01
RU2162082C2 (ru) 2001-01-20
HU9601524D0 (en) 1996-07-29
PL314637A1 (en) 1996-12-09
HUP9601524A3 (en) 2000-03-28
AU5471896A (en) 1996-12-19
DE69622933D1 (de) 2002-09-19
KR100375956B1 (ko) 2003-04-21
CN1066151C (zh) 2001-05-23
CZ291516B6 (cs) 2003-03-12
AR002756A1 (es) 1998-04-29
DE69622933T2 (de) 2003-04-24
NZ286723A (en) 1998-03-25
NO315233B1 (no) 2003-08-04
MX9601994A (es) 1997-08-30
CZ156396A3 (en) 1996-12-11
IL118526A0 (en) 1996-10-16
NO962231D0 (no) 1996-05-31
DK0747385T3 (da) 2002-12-16
EP0747385B1 (en) 2002-08-14
HUP9601524A2 (en) 1997-05-28
EP0747385A1 (en) 1996-12-11
PL187883B1 (pl) 2004-10-29
CN1144805A (zh) 1997-03-12
CA2176191A1 (en) 1996-12-07
NO962231L (no) 1996-12-09
ZA964261B (en) 1997-11-27
AU695959B2 (en) 1998-08-27
JPH08337589A (ja) 1996-12-24

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Legal Events

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E701 Decision to grant or registration of patent right
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Year of fee payment: 4

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