KR950013482A - 복합 임플란트재 및 그의 제조방법 - Google Patents

복합 임플란트재 및 그의 제조방법 Download PDF

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Publication number
KR950013482A
KR950013482A KR1019930024040A KR930024040A KR950013482A KR 950013482 A KR950013482 A KR 950013482A KR 1019930024040 A KR1019930024040 A KR 1019930024040A KR 930024040 A KR930024040 A KR 930024040A KR 950013482 A KR950013482 A KR 950013482A
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South Korea
Prior art keywords
layer
calcium phosphate
composite implant
implant material
porous surface
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KR1019930024040A
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English (en)
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KR960010743B1 (ko
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김수룡
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우덕창
쌍용양회공업주식회사
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Priority to KR1019930024040A priority Critical patent/KR960010743B1/ko
Publication of KR950013482A publication Critical patent/KR950013482A/ko
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Publication of KR960010743B1 publication Critical patent/KR960010743B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/06—Titanium or titanium alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C4/00—Coating by spraying the coating material in the molten state, e.g. by flame, plasma or electric discharge
    • C23C4/12—Coating by spraying the coating material in the molten state, e.g. by flame, plasma or electric discharge characterised by the method of spraying
    • C23C4/134—Plasma spraying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00011—Metals or alloys
    • A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Metallurgy (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)

Abstract

본 발명은 티타늄 또는 티타늄합금등으로 된 금속 임플란트 모재(1에 플라스마 용사법에 의한 인산 칼슘화합물의 제1층인 치밀층(2)으로 된 복합 임플란트재에 있어서, 생체경조식(뼈)의 생성을 촉진합과 동시에 임플란트재와 생체경조직과의 결합력을 증진시키게 하는 제2층인 다공성 표면층(3)을 형성하기 위하여 알루미늄 분말과 인상칼슘화합물 분말을 중량비로 1:1.8 내지 1:10.5의 범위로 혼합하여 상기 제1층의 치밀층(2)위에 플라스마 용사하고, 이어서 이것을 알카리용액으로 처리하여 상기 알루미늄이 제거된 부위가 기공으로 생성되는 것이 추가로 이루어지는 복합 임플란트재 및 그의 제조방법이다.
강인한 금속 임플란트 모재(1), 인산칼슘화합물의 치밀층(2), 그리고 다공성 표면층(3)으로 구성된 본 발명에 의한 복합 임플란트재는 각각의 특성을 발휘하면서 서로의 단점을 보완해주는 특성을 보유하게 된다.

Description

복합 임플란트재 및 그의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명의 의한 복합 임플란트의 단면도이다.

Claims (5)

  1. 금속 임플란트 모재(1)와 그 위에 인산칼슘화합물의 치밀층(2)으로 된 복합 임플란트재에 있어서, 이위에 인산칼슘화합물로 된 다공성 표면층(3)이 추가로 이루어지는 것을 특징으로 하는 복합 임플란트재.
  2. 제1항에 있어서, 다공성 표면층(3)은 기공율 20 내지 50%, 기공경 1 내지 50㎛, 두께 100 내지 300㎛인 것을 특징으로 하는 복합 임플란트재.
  3. 금속 임플란트 모재(1)에 플라즈마 용사법에 의해 고순도 인산칼슘화합물로 제1층인 치밀층(2)의 복합 임플란트재를 제조하는 방법에 있어서, 알루미늄 분말과 인산칼슘화합물 분말을 중량비로 1 : 1.8 내지 1 : 10.5의 범위로 혼합하여 상기 제1층의 치밀층(2)위에 플라스마 용사하고, 이어서 이것을 알칼리용액으로 처리하여 상기 알루미늄이 제거된 부위가 기공으로 생성되어 제2층의 다공성 표면층(3)이 형성되는 것을 특징으로 하는 복합 임플란트의 제조방법.
  4. 제3항에 있어서, 제2층의 다공성 표면층(3)에 플라스마 용사되는 알루미늄 및 인산칼슘화합물 분말의 입자크기는 100 내지 200㎛ 범위로 하는 것을 특징으로 하는 복합 임플란트의 제조방법.
  5. 제3항에 있어서, 알칼리 용액은 0.1몰 농도의 수산화나트륨 또는 수산화칼륨 용액인 것을 특징으로 하는 복합 임플란트의 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930024040A 1993-11-12 1993-11-12 복합 임플란트재 및 그의 제조방법 KR960010743B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019930024040A KR960010743B1 (ko) 1993-11-12 1993-11-12 복합 임플란트재 및 그의 제조방법

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Application Number Priority Date Filing Date Title
KR1019930024040A KR960010743B1 (ko) 1993-11-12 1993-11-12 복합 임플란트재 및 그의 제조방법

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KR950013482A true KR950013482A (ko) 1995-06-15
KR960010743B1 KR960010743B1 (ko) 1996-08-08

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100655170B1 (ko) * 2005-04-07 2006-12-08 한국과학기술원 대퇴부에 사용되는 인공 관절 장치
WO2007040298A1 (en) * 2005-10-04 2007-04-12 Megagen Corp. Electrolyte solution for implant surface treatment, method for implant surface treatment using the same, and implant manufactured by the same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100655170B1 (ko) * 2005-04-07 2006-12-08 한국과학기술원 대퇴부에 사용되는 인공 관절 장치
WO2007040298A1 (en) * 2005-10-04 2007-04-12 Megagen Corp. Electrolyte solution for implant surface treatment, method for implant surface treatment using the same, and implant manufactured by the same

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Publication number Publication date
KR960010743B1 (ko) 1996-08-08

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