KR950005921A - Compositions to Promote Wound Treatment - Google Patents

Compositions to Promote Wound Treatment Download PDF

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Publication number
KR950005921A
KR950005921A KR1019930016390A KR930016390A KR950005921A KR 950005921 A KR950005921 A KR 950005921A KR 1019930016390 A KR1019930016390 A KR 1019930016390A KR 930016390 A KR930016390 A KR 930016390A KR 950005921 A KR950005921 A KR 950005921A
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KR
South Korea
Prior art keywords
group
composition
wound treatment
promoting
triazol
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Application number
KR1019930016390A
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Korean (ko)
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KR100242479B1 (en
Inventor
아키라 세오
구니카즈 히라가
히로야스 고가
요시미 니와노
Original Assignee
무라다 도시카즈
니혼노야쿠 가부시키가이샤
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Application filed by 무라다 도시카즈, 니혼노야쿠 가부시키가이샤 filed Critical 무라다 도시카즈
Priority to KR1019930016390A priority Critical patent/KR100242479B1/en
Publication of KR950005921A publication Critical patent/KR950005921A/en
Application granted granted Critical
Publication of KR100242479B1 publication Critical patent/KR100242479B1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

일반식(Ⅰ)의 화합물을 활성성분으로서 포함하는 상처 치료를 촉진시키기 위한 조성물에 대해 기술하였다.A composition for promoting wound healing comprising the compound of formula (I) as an active ingredient has been described.

상기식에서, R은 수소원자, 페닐 그룹 또는, 할로겐 원자, C1-C6알킬그룹, 하이드록실 그룹 또는 C1-C6알콕시 그룹에 의해 치환된 페닐 그룹이고, X는 1-이미다졸릴 그룹 또는 1,2,4-트리아졸-1-일 그룹이다.Wherein R is a hydrogen atom, a phenyl group or a phenyl group substituted by a halogen atom, a C 1 -C 6 alkyl group, a hydroxyl group or a C 1 -C 6 alkoxy group, and X is a 1-imidazolyl group Or 1,2,4-triazol-1-yl group.

Description

상처 치료를 촉진시키기 위한 조성물Compositions to Promote Wound Treatment

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (6)

활성 성분으로서의 일반식(Ⅰ)의 화합물 및 약제학적으로 허용되는 담체를 포함함을 특징으로 하는, 상처 치료를 촉진시키기 위한 조성물.A composition for promoting wound healing comprising a compound of formula (I) as an active ingredient and a pharmaceutically acceptable carrier. 상기식에서, R은 수소원자, 페닐 그룹 또는, 할로겐 원자, C1-C6알킬그룹, 하이드록실 그룹 또는 C1-C6알콕시 그룹에 의해 치환된 페닐 그룹이고, X는 1-이미다졸릴 그룹 또는 1,2,4-트리아졸-1-일 그룹이다.Wherein R is a hydrogen atom, a phenyl group or a phenyl group substituted by a halogen atom, a C 1 -C 6 alkyl group, a hydroxyl group or a C 1 -C 6 alkoxy group, and X is a 1-imidazolyl group Or 1,2,4-triazol-1-yl group. 제1항에 있어서, R이 o-클로로페닐 그룹, p-하이드록시 페닐 그룹 또는 p-톨릴 그룹인 조성물.The composition of claim 1 wherein R is an o-chlorophenyl group, p-hydroxy phenyl group or p-tolyl group. 제1항 또는 제2항에 있어서, 국소용으로 사용하기 위한 조성물.The composition of claim 1 or 2 for topical use. 제1항 또는 제2항의 상처 치료를 촉진시키기 위한 조성물을, 상처 치료를 촉진시킬 필요가 있는 환자에게 투여함을 특징으로 하여, 상처 치료를 촉진시키는 방법.A method for promoting wound treatment, characterized in that the composition for promoting wound treatment of claim 1 or 2 is administered to a patient in need of promoting the wound treatment. 제4항에 있어서, 조성물을 상처에 국소 투여하는 방법.The method of claim 4, wherein the composition is administered topically to the wound. 일반식(Ⅰ′)의 화합물.Compound of general formula (I '). 상기식에서, X는 1-이미다졸릴 그룹 또는 1,2,4-트리아졸-1-일 그룹이다.Wherein X is a 1-imidazolyl group or 1,2,4-triazol-1-yl group. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019930016390A 1993-08-24 1993-08-24 Composition for accelerating healing of wound KR100242479B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019930016390A KR100242479B1 (en) 1993-08-24 1993-08-24 Composition for accelerating healing of wound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019930016390A KR100242479B1 (en) 1993-08-24 1993-08-24 Composition for accelerating healing of wound

Publications (2)

Publication Number Publication Date
KR950005921A true KR950005921A (en) 1995-03-20
KR100242479B1 KR100242479B1 (en) 2000-03-02

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ID=19361779

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930016390A KR100242479B1 (en) 1993-08-24 1993-08-24 Composition for accelerating healing of wound

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KR (1) KR100242479B1 (en)

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Publication number Publication date
KR100242479B1 (en) 2000-03-02

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