KR930702509A - 사람 면역결핍 바이러스(hiv)면역치료제 - Google Patents

사람 면역결핍 바이러스(hiv)면역치료제

Info

Publication number
KR930702509A
KR930702509A KR1019930701196A KR930701196A KR930702509A KR 930702509 A KR930702509 A KR 930702509A KR 1019930701196 A KR1019930701196 A KR 1019930701196A KR 930701196 A KR930701196 A KR 930701196A KR 930702509 A KR930702509 A KR 930702509A
Authority
KR
South Korea
Prior art keywords
hiv
protein
capacity
immunotherapy
infected
Prior art date
Application number
KR1019930701196A
Other languages
English (en)
Other versions
KR100251823B1 (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR930702509A publication Critical patent/KR930702509A/ko
Application granted granted Critical
Publication of KR100251823B1 publication Critical patent/KR100251823B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • AIDS & HIV (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019930701196A 1991-08-22 1992-08-24 사람 면역 결핍 바이러스(hiv) 감염의 면역치료용 모노클로날 항체 KR100251823B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74856291A 1991-08-22 1991-08-22
US7/748,562 1991-08-22
PCT/US1992/007111 WO1993004090A1 (en) 1991-08-22 1992-08-24 Hiv immunotherapeutics

Publications (2)

Publication Number Publication Date
KR930702509A true KR930702509A (ko) 1993-09-09
KR100251823B1 KR100251823B1 (ko) 2000-04-15

Family

ID=25009973

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930701196A KR100251823B1 (ko) 1991-08-22 1992-08-24 사람 면역 결핍 바이러스(hiv) 감염의 면역치료용 모노클로날 항체

Country Status (9)

Country Link
EP (1) EP0554446B1 (ko)
JP (1) JP2888980B2 (ko)
KR (1) KR100251823B1 (ko)
AT (1) ATE173024T1 (ko)
AU (1) AU659677B2 (ko)
CA (1) CA2094611C (ko)
DE (1) DE69227500T2 (ko)
RU (1) RU2128222C1 (ko)
WO (1) WO1993004090A1 (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995006119A1 (en) * 1993-08-24 1995-03-02 Scotgen Limited Recombinant humanized anti-human immunodeficiency virus antibody
JP2888981B2 (ja) * 1992-08-24 1999-05-10 日清食品株式会社 Ｈｉｖ免疫療法
AU681633B2 (en) * 1993-03-11 1997-09-04 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Anti-HIV monoclonal antibody
US5618922A (en) 1994-07-25 1997-04-08 Nissin Shokuhin Kabushiki Kaisha NM03 antibody materials and methods
US6193982B1 (en) 1995-04-27 2001-02-27 The United States Of America As Represented By The Department Of Health & Human Services Anti-cyanovirin antibody with an internal image of gp120, a method of use thereof, and a method of using a cyanovirin to induce an immune response to gp120
US6987096B1 (en) 1995-04-27 2006-01-17 The United States Of America As Represented By The Department Of Health And Human Services Antiviral proteins and peptides, DNA coding sequences therefor, and uses thereof
US6780847B2 (en) 1995-04-27 2004-08-24 The United States Of America As Represented By The Department Of Health And Human Services Glycosylation-resistant cyanovirins and related conjugates, compositions, nucleic acids, vectors, host cells, methods of production and methods of using nonglycosylated cyanovirins
US6428790B1 (en) 1995-04-27 2002-08-06 The United States Of America As Represented By The Secretary Department Of Health And Human Services Cyanovirin conjugates and matrix-anchored cyanovirin and related compositions and methods of use
US5843882A (en) 1995-04-27 1998-12-01 The United States Of America As Represented By The Department Of Health And Human Services Antiviral proteins and peptides
US7048935B2 (en) 1995-04-27 2006-05-23 The United States Of America As Represented By The Department Of Health And Human Services Cyanovirin conjugates and matrix-anchored cyanovirin and related compositions and methods of use
AU2487300A (en) 1998-12-31 2000-07-31 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
WO2000039303A2 (en) 1998-12-31 2000-07-06 Chiron Corporation Modified hiv env polypeptides
CN1339319A (zh) * 2000-08-18 2002-03-13 清华大学 一种治疗艾滋病的药物及其制备方法
DE60221705T2 (de) 2001-03-22 2008-06-05 The United States of America, represented by the Secretary, Dept. of Health and Human Services, the Natl. Institutes of Health, Office of Technology Transfer Glykosylierungsresistente cyanovirine und damit verbundene konjugate, zusammensetzungen, nukleinsäuren, vektoren, wirtszellen, herstellungsverfahren sowie verfahren zur verwendung nichtglykosylierter cyanovirine
AU2002320314A1 (en) 2001-07-05 2003-01-21 Chiron, Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3885355T2 (de) * 1987-05-29 1994-06-01 Shuzo Matsushita Monoklonale Antikörper.
CA1339857C (en) * 1987-05-29 1998-05-05 Cecily Rou-Yun Sun Monoclonal antibodies to gp120 which neutraleze hiv-1
EP0339504A3 (en) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
CA2058630A1 (en) * 1989-06-05 1990-12-06 Charles F. Scott, Jr. Human monoclonal antibodies to hiv-1 mn gp 120
JP2989862B2 (ja) * 1990-07-02 1999-12-13 財団法人化学及血清療法研究所 モノクローナル抗体

Also Published As

Publication number Publication date
JP2888980B2 (ja) 1999-05-10
DE69227500T2 (de) 1999-04-15
EP0554446B1 (en) 1998-11-04
EP0554446A4 (ko) 1994-02-09
RU2128222C1 (ru) 1999-03-27
WO1993004090A1 (en) 1993-03-04
AU2568392A (en) 1993-03-16
ATE173024T1 (de) 1998-11-15
EP0554446A1 (en) 1993-08-11
KR100251823B1 (ko) 2000-04-15
CA2094611A1 (en) 1993-02-23
DE69227500D1 (de) 1998-12-10
CA2094611C (en) 2000-07-25
JPH06503970A (ja) 1994-05-12
AU659677B2 (en) 1995-05-25

Similar Documents

Publication Publication Date Title
KR930702509A (ko) 사람 면역결핍 바이러스(hiv)면역치료제
JPH06502539A (ja) Ｈｉｖ−１　ｇｐ１２０のｖ３ループおよびｃｄ−４結合部位に特異的な中和ヒトモノクローナル抗体
AT398080B (de) Immortalisierte zellinie, verfahren zu ihrer herstellung und verfahren zur herstellung von monoklonalen antikörpern sowie diagnoseverfahren und -mittel
ATE238420T1 (de) Rekombinanter humanisierter antikörper gegen menschlichen immunschwächevirus
US5854400A (en) Monoclonal antibodies which neutralize HIV-1 infection
RU93005284A (ru) Моноклональные антитела линии клеток, фармацевтические композиции, способы лечения, фрагмент антитела
US6132721A (en) Non-Toxic immunogens derived from a retroviral regulatory protein, antibodies, preparation method therefor, and pharmaceutical compositions containing same
WO1990010457A1 (en) Method of treating hiv infections using immunotoxins
US6241986B1 (en) Human monoclonal antibodies to the CD4-binding domain of HIV, uses thereof and synergistic neutralization of HIV
US5445960A (en) Monoclonal antibodies specific for HIV and hybridomas for their production
JPH05503851A (ja) 中和および／またはａｄｃｃ仲介モノクローナルｈｉｖ抗体
KR0149848B1 (ko) Hiv에 특이한 모노클로날 항체 및 그 제조용 하이브리도마
AU8010791A (en) Hiv monoclonal antibody
US5820865A (en) Method to induce cytotoxic T Lymphocytes specific for a broad array of HIV-1 isolates using hybrid synthetic peptides
US6200575B1 (en) Non-toxic immunogens derived from a retroviral regulatory protein antibodies preparation process and pharmaceutical compositions comprising them
ATE201698T1 (de) Immuntherapeutika gegen hiv
CN1172717C (zh) 一种治疗艾滋病的药物及其制备方法
AU651794B2 (en) Human monoclonal antibodies to human immunodeficiency virus
RU94024562A (ru) Антитело, полинуклеотид, клетка, способ получения антитела
Benjouad et al. Effect of sialic acid removal on the antibody response to the third variable domain of human immunodeficiency virus type‐1 envelope glycoprotein
CA2160696A1 (en) Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus
CN1238499C (zh) 艾滋病病毒0型株的一种抗体及其生产细胞系与应用
EP0491888A4 (en) Immunotherapeutic compositions for treating and preventing aids, arc and hiv infection
KR100871455B1 (ko) Ｈｉｖ 바이러스에 대한 천연 항체
WO2002026253A1 (fr) Vaccin contre le sida, son procede de preparation et ses applications

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
LAPS Lapse due to unpaid annual fee