KR920703060A - 제약학적 배합물 - Google Patents

제약학적 배합물

Info

Publication number
KR920703060A
KR920703060A KR1019920701762A KR920701762A KR920703060A KR 920703060 A KR920703060 A KR 920703060A KR 1019920701762 A KR1019920701762 A KR 1019920701762A KR 920701762 A KR920701762 A KR 920701762A KR 920703060 A KR920703060 A KR 920703060A
Authority
KR
South Korea
Prior art keywords
pharmaceutical combination
fencyclovir
combination according
propylene glycol
water
Prior art date
Application number
KR1019920701762A
Other languages
English (en)
Other versions
KR0170414B1 (ko
Inventor
앤 그리피드스 헤이즐
존 굳댈 앨런
오두로-예보아
Original Assignee
원본미기재
비이참 그루우프 피이엘시이
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 원본미기재, 비이참 그루우프 피이엘시이 filed Critical 원본미기재
Publication of KR920703060A publication Critical patent/KR920703060A/ko
Application granted granted Critical
Publication of KR0170414B1 publication Critical patent/KR0170414B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

내용 없음

Description

제약학적 배합물
[도면의 간단한 설명]
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (12)

  1. 최소한 30%의 프로필렌 글리콜 및 가용화 펜시클로비르를 함유한, 피부 또는 점막의 비루스 감염을 치료하기 위한 수증유 또는 수성 국소적인 제약학적 배합물.
  2. 제1항에 있어서, 0.075-10%의 펜시클로비르, 30-60%의 프로필렌 글리콜 및 최소한 15%의 물을 함유한 제약학적 배합물.
  3. 제2항에 있어서, 0.5-10%의 펜시클로비르, 30-50%의 프로필렌 글리콜 및 최소한 20%의 물을 함유하는 제약학적 배합물.
  4. 제3항에 있어서, 유상과 함께 2-8%의 펜시클로비르, 35-45%의 프로필렌 글리콜 및 25-40%의 물을 함유하는 제약학적 배합물.
  5. 제1-4항 중 어느 한 항에 있어서, 5%의 펜시클로비르를 함유한 제약학적 배합물.
  6. 제1항에 있어서, 실시예들을 참고로 명세서에 기술된 바와 실질적으로 같은 제약학적 배합물.
  7. 펜시클로비르, 프로필렌 글리콜 및 물의 조합물을, 임의적으로 유상과 혼합함으로 구성된, 제1항에 따른 제약학적 배합물의 제조 방법.
  8. 활성 치료 물질로서 사용하기 위한 제1항에 따른 제약학적 배합물.
  9. 비루스성 감염의 치료에 사용하기 위한 제l항에 따른 제약학적 배합물.
  10. 비루스성 감염의 치료에 사용하기 위한 약물의 제조에 있어서 제1항에 따른 제약학적 배합물의 사용.
  11. 제1항에 따른 제약학적 배합물의 효과량을 투여함으로 구성되는, 포유동물에 있어서 비루스성 감염의 치료 방법.
  12. ※ 참고사항:최초출원 내용에 의하여 공개되는 것임.
KR1019920701762A 1990-01-26 1991-01-24 펜시클로비르를 함유한 새로운 제약학적 배합물 KR0170414B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9001886,2 1990-01-26
GB9001886.2 1990-01-26
GB909001886A GB9001886D0 (en) 1990-01-26 1990-01-26 Pharmaceutical formulation
PCT/GB1991/000102 WO1991011187A1 (en) 1990-01-26 1991-01-24 Pharmaceutical formulation

Publications (2)

Publication Number Publication Date
KR920703060A true KR920703060A (ko) 1992-12-17
KR0170414B1 KR0170414B1 (ko) 1999-02-18

Family

ID=10669997

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920701762A KR0170414B1 (ko) 1990-01-26 1991-01-24 펜시클로비르를 함유한 새로운 제약학적 배합물

Country Status (29)

Country Link
EP (1) EP0511991B1 (ko)
JP (1) JP2545317B2 (ko)
KR (1) KR0170414B1 (ko)
CN (1) CN1056058C (ko)
AP (1) AP197A (ko)
AT (1) ATE142880T1 (ko)
AU (1) AU643975B2 (ko)
CA (1) CA2074503C (ko)
CY (2) CY1984A (ko)
DE (1) DE69122229T2 (ko)
DK (1) DK0511991T3 (ko)
ES (1) ES2092559T3 (ko)
FI (1) FI101600B (ko)
GB (1) GB9001886D0 (ko)
GR (1) GR3021385T3 (ko)
HK (1) HK218996A (ko)
HU (1) HU215842B (ko)
IE (1) IE910249A1 (ko)
IL (1) IL97008A (ko)
LU (1) LU90110I2 (ko)
MA (1) MA22051A1 (ko)
MY (1) MY110074A (ko)
PL (1) PL166678B1 (ko)
PT (1) PT96563B (ko)
SA (1) SA91110341B1 (ko)
SG (1) SG49144A1 (ko)
TW (1) TW307687B (ko)
WO (1) WO1991011187A1 (ko)
ZA (1) ZA91525B (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9114939D0 (en) * 1991-07-11 1991-08-28 Smithkline Beecham Plc Pharmaceutical formulation
US6124304A (en) * 1993-10-05 2000-09-26 Smithkline Beecham Plc Penciclovir for the treatment of zoster associated pain
GB9326177D0 (en) * 1993-12-22 1994-02-23 Smithkline Beecham Plc Pharmaceuticals
GB9601544D0 (en) 1996-01-26 1996-03-27 Smithkline Beecham Plc Pharmaceuticals
US7223387B2 (en) 1998-11-18 2007-05-29 Medivir Ab Antiviral formulations comprising propylene glycol and an isopropyl alkanoic acid ester
WO2017029298A1 (en) 2015-08-17 2017-02-23 Sanovel Ilac Sanayi Ve Ticaret A.S. A topical antiviral composition
WO2019195802A1 (en) 2018-04-05 2019-10-10 Bausch Health Ireland Limited Polymeric emulsion delivery systems

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
KR830005852A (ko) * 1980-07-18 1983-09-14 미첼 페터 잭슨 피부와 점막의 비루스 감염치료에 적합한 국소치료제의 제조방법
GB2080106B (en) * 1980-07-18 1984-03-07 Weelcome Foundation Ltd Acyclovin preparations
EP0095813A3 (en) * 1982-06-01 1985-05-08 THE PROCTER & GAMBLE COMPANY Penetrating topical pharmaceutical compositions containing 9-(2-hydroxyethoxymethyl) guanine
DE3485225D1 (de) * 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
DE3571810D1 (en) * 1984-01-26 1989-08-31 Merck & Co Inc Substituted butyl guanines and their utilization in antiviral compositions
DE3671227D1 (de) * 1985-07-27 1990-06-21 Beecham Group Plc 9-substituierte guaninmonohydrate.

Also Published As

Publication number Publication date
IL97008A0 (en) 1992-03-29
ZA91525B (en) 1992-02-26
HU9202431D0 (en) 1992-10-28
CN1056058C (zh) 2000-09-06
EP0511991A1 (en) 1992-11-11
HK218996A (en) 1997-01-03
CA2074503C (en) 1999-12-14
AP9000236A0 (en) 1991-01-31
WO1991011187A1 (en) 1991-08-08
CN1053547A (zh) 1991-08-07
CY1984A (en) 1997-09-05
EP0511991B1 (en) 1996-09-18
DK0511991T3 (da) 1996-11-11
GR3021385T3 (en) 1997-01-31
AP197A (en) 1992-06-30
FI101600B1 (fi) 1998-07-31
IL97008A (en) 1995-05-26
JPH05503695A (ja) 1993-06-17
AU643975B2 (en) 1993-12-02
PL166678B1 (pl) 1995-06-30
IE910249A1 (en) 1991-07-31
TW307687B (ko) 1997-06-11
SA91110341B1 (ar) 2004-05-25
DE69122229T2 (de) 1997-03-06
JP2545317B2 (ja) 1996-10-16
KR0170414B1 (ko) 1999-02-18
FI923371A (fi) 1992-07-24
SG49144A1 (en) 1998-05-18
AU7155891A (en) 1991-08-21
GB9001886D0 (en) 1990-03-28
FI101600B (fi) 1998-07-31
CA2074503A1 (en) 1991-07-27
MA22051A1 (fr) 1991-10-01
PT96563A (pt) 1991-10-15
CY1999020I2 (en) 2009-11-04
ATE142880T1 (de) 1996-10-15
HU215842B (hu) 2001-02-28
PT96563B (pt) 1998-07-31
ES2092559T3 (es) 1996-12-01
HUT62472A (en) 1993-05-28
LU90110I2 (fr) 1997-09-25
DE69122229D1 (de) 1996-10-24
FI923371A0 (fi) 1992-07-24
MY110074A (en) 1997-12-31

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