KR910021394A - 카르복실산 유도체 - Google Patents

카르복실산 유도체 Download PDF

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Publication number
KR910021394A
KR910021394A KR1019910003131A KR910003131A KR910021394A KR 910021394 A KR910021394 A KR 910021394A KR 1019910003131 A KR1019910003131 A KR 1019910003131A KR 910003131 A KR910003131 A KR 910003131A KR 910021394 A KR910021394 A KR 910021394A
Authority
KR
South Korea
Prior art keywords
carboxylic acid
methyl
complex
zinc
pharmaceutical composition
Prior art date
Application number
KR1019910003131A
Other languages
English (en)
Inventor
와트슨 클리테로우 존
윌리엄 콜링톤 에리스
Original Assignee
배리 안토니 뉴샘
글락소 그룹 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 배리 안토니 뉴샘, 글락소 그룹 리미티드 filed Critical 배리 안토니 뉴샘
Publication of KR910021394A publication Critical patent/KR910021394A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Abstract

내용 없음

Description

카르복실산 유도체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (9)

  1. 타르타르산, 시트르산 및 알킬 시트르산으로부터 선택된 카르복실산과 아연의 착물과, 라니터딘으로 형성된 염 또는 그의 용해화물.
  2. 제1항에 있어서, 카르복실산이 시트르산인것을 특징으로 하는 염.
  3. Ｎ-〔2-〔〔〔5-〔(디메틸아미노)메틸〕-2-퓨라닐〕메틸〕티오〕에틸〕-Ｎ＇-메틸-2-니트로-1,1-에텐디아민 2-히드록시-1, 2, 3-프로판트라카르복실 레이트 아연(2＋)착물, 및 그의 용매화물.
  4. 라니티딘을 적절한 용매중에서 아연과 카르복실산의 착물과 반응시킨 후, 생성된 염을 용액으로부터 분리하는 것으로 이루어진 것을 특징으로 하는, 제1항 내지 제3항중 어느 한 항에 의한 염의 제조방법.
  5. 제4항에 있어서, 용매가 물인 것을 특징으로 하는 방법.
  6. 제4항 또는 제5항에 있어서, 반응을 20-60℃의 온도에서 행하는 것을 특징으로 하는 방법.
  7. 제약학적으로 허용되는 1종 이상의 담체 또는 부형제와 함께 제1항 내지 제3항중 어느 한 항에 의한 염을 함유하는 제약 조성물.
  8. 제7항에 있어서, 조성물이 경구투여용으로 적절한 형태인 제약 조성물.
  9. 제8항에 있어서, 조성물이 정제형태인 제약 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019910003131A 1990-02-27 1991-02-26 카르복실산 유도체 KR910021394A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909004328A GB9004328D0 (en) 1990-02-27 1990-02-27 Chemical compounds
GB9004328.2 1990-02-27

Publications (1)

Publication Number Publication Date
KR910021394A true KR910021394A (ko) 1991-12-20

Family

ID=10671650

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910003131A KR910021394A (ko) 1990-02-27 1991-02-26 카르복실산 유도체

Country Status (11)

Country Link
US (1) US5399556A (ko)
EP (1) EP0445949A1 (ko)
JP (1) JPH04217676A (ko)
KR (1) KR910021394A (ko)
AU (1) AU639980B2 (ko)
CA (1) CA2037081A1 (ko)
GB (1) GB9004328D0 (ko)
IE (1) IE910655A1 (ko)
PT (1) PT96879A (ko)
TW (1) TW219362B (ko)
ZA (1) ZA911398B (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH679582A5 (ko) * 1988-07-18 1992-03-13 Glaxo Group Ltd
AUPM456894A0 (en) * 1994-03-18 1994-04-14 Glyzinc Pharmaceuticals Limited Treatment for gastric disorders
DE9420259U1 (de) * 1994-12-17 1995-02-09 Roehm Gmbh Entbittertes Ranitidin-Präparat
GB9621273D0 (en) * 1996-10-11 1996-11-27 Cortecs Ltd Therapeutic method
AU2007216671B2 (en) * 2007-07-09 2009-07-16 Cypress Pharmaceutical, Inc. Pleasant-tasting ranitidine formulation
USD666493S1 (en) 2010-11-01 2012-09-04 Colgate-Palmolive Company Cap for a container
USD666492S1 (en) 2010-11-01 2012-09-04 Colgate-Palmolive Company Cap for a container
USD666099S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666098S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666097S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666096S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
BE905235A (fr) * 1986-08-05 1986-12-01 Hasunor Ag Ascorbates antagonistes des recepteurs h2 et leur procede de preparation.
CH670089A5 (en) * 1987-02-20 1989-05-12 Hasunor Ag Ascorbyl derivs. of H2 receptor antagonists - prepd. by reacting corresp. acid with base in organic solvent and refluxing
ES2009921A6 (es) * 1988-05-26 1989-10-16 Vinas Lab Procedimiento para la obtencion de derivados imidazolicos.
ES2007948A6 (es) * 1988-07-06 1989-07-01 Vinas Lab Procedimiento para la obtencion de derivados propargilguanidicos.
ES2007959A6 (es) * 1988-07-11 1989-07-01 Vinas Lab Procedimiento para la obtencion de derivados tiazolicos.
CH679582A5 (ko) * 1988-07-18 1992-03-13 Glaxo Group Ltd
ES2012285A6 (es) * 1989-03-09 1990-03-01 Vinas Lab Procedimiento para la obtencion de derivados furanicos.

Also Published As

Publication number Publication date
PT96879A (pt) 1991-10-31
AU639980B2 (en) 1993-08-12
EP0445949A1 (en) 1991-09-11
GB9004328D0 (en) 1990-04-25
JPH04217676A (ja) 1992-08-07
US5399556A (en) 1995-03-21
IE910655A1 (en) 1991-08-28
AU7139591A (en) 1991-08-29
CA2037081A1 (en) 1991-08-28
ZA911398B (en) 1992-02-26
TW219362B (ko) 1994-01-21

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