KR910002469A - Method of manufacturing ^ 99mTC-labeled radiopharmaceutical for diagnosing liver and biliary tracts - Google Patents

Method of manufacturing ^ 99mTC-labeled radiopharmaceutical for diagnosing liver and biliary tracts Download PDF

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Publication number
KR910002469A
KR910002469A KR1019890010338A KR890010338A KR910002469A KR 910002469 A KR910002469 A KR 910002469A KR 1019890010338 A KR1019890010338 A KR 1019890010338A KR 890010338 A KR890010338 A KR 890010338A KR 910002469 A KR910002469 A KR 910002469A
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KR
South Korea
Prior art keywords
99mtc
manufacturing
iotida
diagnosing liver
labeled radiopharmaceutical
Prior art date
Application number
KR1019890010338A
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Korean (ko)
Other versions
KR920005662B1 (en
Inventor
김재록
박경배
오옥두
한광희
박응우
Original Assignee
한필순
재단법인 한국에너지 연구소
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Priority to KR1019890010338A priority Critical patent/KR920005662B1/en
Publication of KR910002469A publication Critical patent/KR910002469A/en
Application granted granted Critical
Publication of KR920005662B1 publication Critical patent/KR920005662B1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

내용 없음No content

Description

간. 담도계 진단용99mTC 표지 방사성의 약품의 제조방법liver. Method for manufacturing 99mTC-labeled radiopharmaceutical for diagnosis of biliary tract

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (3)

2,4,6-트리메틸아닐린 (구조식I)을 클로로아세틸염소로 클로로아세틸화, 요오드로 요오드화, 아미노이초산으로 아민화 반응을 차례로 진행시켜 IOTIDA(구조식II)를 제조하는 방법Method for preparing IOTIDA (Formula II) by proceeding chloroacetylation of 2,4,6-trimethylaniline (Formula I) with chloroacetyl chlorine, iodide with iodine, and amination reaction with aminodiacetic acid IOTIDA와 염화제 주석의 혼합액을 동결건조시킨 다음 과테크네튬(99mTC)산 나트륨과 반응시켜99mTC로 표지된 IOTIDA (99mTC-IOTIDA)를 제조하는 방법.The freeze-dried mixture of a tin chloride and IOTIDA following technetium (99m TC) method for producing a IOTIDA (99m TC-IOTIDA) the reaction with sodium was labeled with 99m TC. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019890010338A 1989-07-21 1989-07-21 Process for preparing 3-iode-2,4,6-trimethyl phenyl carbamoil methyl imino diacetic acid KR920005662B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019890010338A KR920005662B1 (en) 1989-07-21 1989-07-21 Process for preparing 3-iode-2,4,6-trimethyl phenyl carbamoil methyl imino diacetic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019890010338A KR920005662B1 (en) 1989-07-21 1989-07-21 Process for preparing 3-iode-2,4,6-trimethyl phenyl carbamoil methyl imino diacetic acid

Publications (2)

Publication Number Publication Date
KR910002469A true KR910002469A (en) 1991-02-25
KR920005662B1 KR920005662B1 (en) 1992-07-13

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ID=19288270

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Application Number Title Priority Date Filing Date
KR1019890010338A KR920005662B1 (en) 1989-07-21 1989-07-21 Process for preparing 3-iode-2,4,6-trimethyl phenyl carbamoil methyl imino diacetic acid

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100695742B1 (en) * 2004-11-30 2007-03-19 한국원자력연구소 A Simple and Fast Procedure for Efficient Synthesis of DISIDA and Its Derivatives or Mebrofenin Using Microwave Irradiation
KR100700419B1 (en) * 2006-12-22 2007-03-28 한국원자력연구소 A Simple and Fast Procedure for Efficient Synthesis of DISIDA and Its Derivatives or Mebrofenin Using Microwave Irradiation

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Publication number Publication date
KR920005662B1 (en) 1992-07-13

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