KR890009578A - 분자 배향된 열가소성 부재 및 이를 제조하는 방법 - Google Patents

분자 배향된 열가소성 부재 및 이를 제조하는 방법 Download PDF

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KR890009578A
KR890009578A KR1019880016636A KR880016636A KR890009578A KR 890009578 A KR890009578 A KR 890009578A KR 1019880016636 A KR1019880016636 A KR 1019880016636A KR 880016636 A KR880016636 A KR 880016636A KR 890009578 A KR890009578 A KR 890009578A
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텅크 데거
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원본미기재
죤슨 앤드 죤스 오서피딕스, 인포포레이티드
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C55/00—Shaping by stretching, e.g. drawing through a die; Apparatus therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C55/00—Shaping by stretching, e.g. drawing through a die; Apparatus therefor
    • B29C55/005—Shaping by stretching, e.g. drawing through a die; Apparatus therefor characterised by the choice of materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C55/00—Shaping by stretching, e.g. drawing through a die; Apparatus therefor
    • B29C55/02—Shaping by stretching, e.g. drawing through a die; Apparatus therefor of plates or sheets
    • B29C55/04—Shaping by stretching, e.g. drawing through a die; Apparatus therefor of plates or sheets uniaxial, e.g. oblique
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary pins, nails or other devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2067/00—Use of polyesters or derivatives thereof, as moulding material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2067/00—Use of polyesters or derivatives thereof, as moulding material
    • B29K2067/04—Polyesters derived from hydroxycarboxylic acids
    • B29K2067/046—PLA, i.e. polylactic acid or polylactide
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
    • B29K2995/0037—Other properties
    • B29K2995/0059—Degradable

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  • Surgery (AREA)
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  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Shaping By String And By Release Of Stress In Plastics And The Like (AREA)
  • Materials For Medical Uses (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Yarns And Mechanical Finishing Of Yarns Or Ropes (AREA)

Abstract

내용 없음

Description

분자 배향된 열가소성 부재 및 이를 제조하는 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제 1도 및 제 1A도는 각각, 예비성형된 막대부재의 측면도 및 단면도이고,
제 2도 및 제 2A도는 각각, 본 발명의 방법에 따라 형성된 막대의 측면도 및 단면도이며,
제 3도 본 발명의 방법 중의 한 형태를 도시하는 개요도.

Claims (24)

  1. 동물체내에 흡수될 수 있는 열가소성 중합체를 제공하고 ; 열가소성 중합체를 용융시키고 ; 열가소성 중합체를 중합체의 유리전이온도 이하의 온도로 냉각시켜, 핵형성을 유발시키고 자체-지체(self-support-ing member)를 형성하고 ; 자체-지지부재를 열가소성 중합체의 유리전이온도 이상 내지 이의 이하의 온도로 재가열하고 ; 이 재가열단계 도중에 자체-지지부재에 장력을 가하고; 여기에 가해진 장력을 유지하면서, 재가열한 자체-지지부재를 냉각시키고 ; 자체-지지부재를 냉각시켜 자체-지지부재가 이완된 후, 장력의 적용을 중단하는 단계를 포함함을 특징으로하여, 자체-지지되는 고강도 열가소성 부재를 제조하는 방법.
  2. 제 1항에 있어서, 열가소성 중가를 압출기에서 처리함으로써 용융시키는 방법.
  3. 제 2항에 있어서, 초기의 냉각단계 도중에 장력을 부재에 가하는 방법.
  4. 제 1항에 있어서, 초기의 냉각단계를, 부재를 냉각유체에 노출시킴으로써 수행하는 방법.
  5. 제 4항에 있어서, 냉각유체가 공기인 방법.
  6. 제 4항에 있어서, 냉각유체가 물인 방법.
  7. 제 6항에 이어서, 물을 분무시킴으로써 적용시키는 방법.
  8. 제 6항에 있어서, 부재를 수욕중에 침지시킴으로써 냉각시키는 방법.
  9. 제 1항에 있어서, 열가소성 중합체를 사출성형기에서 처리함으로써 용융시키는 방법.
  10. 제 9항에 있어서, 열가소성 중합체를 막대(rod)형으로 성형하는 방법.
  11. 제 10항에 있어서, 막대의 말단을 어닐링(annealing)시킨 후 재가열하는 방법.
  12. 제 1항에 있어서, 부재를 재가열하는 도중에 예열시킨 후 장력을 가하는 방법.
  13. 제 12항에 있어서, 장력을 가하는 단계를, 소정의 하중을 가할때까지 부재상에 간격진 두 점 사이에서, 서로에게 종방향으로 소정의 속도로 이동시킨 다음, 상대 운동속도를 서서히 저하시킴으로써 수행하는 방법.
  14. 제 1항에 있어서, 최종 냉각단계를, 부재를 냉각유체에 노출시킴으로써 수행하는 방법.
  15. 제 14항에 있어서, 냉각유체가 물인 방법.
  16. 제 3항에 있어서, 초기의 냉각단계 도중에 부재에 가하는 장력을 3이하의 연신비에서 가하는 방법.
  17. 제 16항에 있어서, 재가열 및 최종 냉각단계 도중에 부재에 가하는 장력이 초기의 냉각단계 도중에 가하는 장력보다 큰 방법.
  18. 제 16항에 있어서, 재강려 및 최종 냉각단계 도중에 부재에 가하는 장력을 3내지 10의 연신비에서 가하는 방법.
  19. 고분자량 폴리락타이드 중합체를 용융시키고 ; 용융된 폴리락타이드 중합체를 목적하는 형태로 제조하고 ; 제조된 부재를 조절된 속도에서 유리전이온도 이하의 온도로 즉시 냉각시켜, 핵 형성을 유발시키고 자체-지지부재를 제조하고 ; 자체-지지부재를 폴리락타이드 중합체의 유리전이온도 이상 내지 실질적으로는 이의 융점이하의 온도로 재가열하고 ; 제조된 부재의 원래 길이의 약 2내지 약 12배의 연신비에서, 상기한 속도에서 자체-지지부재에 장력을 가하여, 자체-지지부재에 고도의 분자배향을 수득하고; 재가열단계 도중에 가한 바와 동일한 수준의 장력을 유지하면서, 재가열한 자체-지지부재를 주위온도로 냉각시키고 ; 자체-지지부재를 냉각시켜 자체-지지부재가 이완된 후, 장력의 적용을 중단하는 단계를 포함함을 특징으로 하여, 자체-지지되는 고강도 열가소성 부재를 제조하는 방법.
  20. 최종 칫수가 예비성형된 부재의 초기칫수와는 실질적으로 상이하며, 형태는 예비성형된 부재의 초기 길이의 2배 이상인 최종길이 및 예비성형된 부재의 초기 횡단면 칫수의 50%미만인 최종 횡단면 칫수에 의해 제한되고, 고도로 분자배향되며, 최종 인장강도는 예비성형된 부재의 최종 인장강도보다 실질적으로 크고, 동물체내에 흡수될 수 있는 열가소성 중합성 재료로 형성되는 자체-지지되는 고강도 부재.
  21. 제 20항에 있어서, 부재가 폴리락타이드 중합체로 형성되는 자체-지지부재.
  22. 제 20항에 있어서, 부재가 압출된 폴리락타이드로 형성되는 자체-지지부재.
  23. 제 20항에 있어서, 부재가 성형된 폴리락타이드로 구성되는 자체-지지부재.
  24. 최종 칫수가 예비성형된 부재의 초기 칫수와는 실질적으로 상이하며, 형태는 예비성형된 부재의 초기길이의 2배이상인 최종길이 및 예비성형된 부재의 초기 횡단면 칫수의 50% 미만인 최종 횡단면 칫수에 의해 제한되고, 고도로 분자배향되며, 최종 인장강도는 예비성형된 부재의 최종 인장강도보다 실질적으로 크고, 동물체내에 흡수될 수 있는 고분자량 L(-)락타이드 중합체로 형성되는 자체-지지되는 대형(large profile)고강도 골고정장치(bone fixation derice).
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR88016636A 1987-12-14 1988-12-14 Moleculary oriented thermoplastic member and process of forming the same KR970002305B1 (en)

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US13275587A 1987-12-14 1987-12-14
US132,755 1987-12-14

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KR (1) KR970002305B1 (ko)
AU (2) AU616225B2 (ko)
BR (1) BR8806560A (ko)
CA (1) CA1311887C (ko)
DE (1) DE3852993T3 (ko)
ES (1) ES2068836T5 (ko)
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FI95220C (fi) 1996-01-10
BR8806560A (pt) 1989-08-22
CA1311887C (en) 1992-12-29
AU616225B2 (en) 1991-10-24
DE3852993D1 (de) 1995-03-23
EP0321176A2 (en) 1989-06-21
EP0321176A3 (en) 1991-09-11
FI885765A (fi) 1989-06-15
AU7379991A (en) 1991-06-13
DE3852993T3 (de) 2004-12-16
AU2669388A (en) 1989-06-15
ES2068836T5 (es) 2004-11-01
DE3852993T2 (de) 1995-06-01
FI885765A0 (fi) 1988-12-13
EP0321176B2 (en) 2004-03-24
EP0321176B1 (en) 1995-02-08
ES2068836T3 (es) 1995-05-01
FI95220B (fi) 1995-09-29
KR970002305B1 (en) 1997-02-27
AU648544B2 (en) 1994-04-28

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