KR880006359A - 사람의 tiits를 제조하기 위한 중간물질로서의 균일한 양 tiits 및 이의 용도 - Google Patents
사람의 tiits를 제조하기 위한 중간물질로서의 균일한 양 tiits 및 이의 용도 Download PDFInfo
- Publication number
- KR880006359A KR880006359A KR870013131A KR870013131A KR880006359A KR 880006359 A KR880006359 A KR 880006359A KR 870013131 A KR870013131 A KR 870013131A KR 870013131 A KR870013131 A KR 870013131A KR 880006359 A KR880006359 A KR 880006359A
- Authority
- KR
- South Korea
- Prior art keywords
- t11ts
- sheep
- human
- immunized
- ser
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Veterinary Medicine (AREA)
- Developmental Biology & Embryology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (9)
- 서역식(Ⅰ)의 아미노산 조성물 및 서열식(Ⅰ)의 N-말단을 갖는 균질한 양 T11TS 및 이의 변형체.VaL/Phe-Ser- GLn/Ser-ASP-ILe-Tyr-GLy-ALa-Met-Asn-GLy-Y-VaL-Thr-Phe-Tyr-VaL-Ser-Glu-Ser-Gln-Phhe-Thr-GLu-ILe-Met-Lys상기 서열식(Ⅱ)에서 X및 Y는 천연아미노산을 나타내고, Y는 바람직하게는 세린이다.
- 동물을 균질한 양 T11TS로 면역시킴을 특징으로 하여, 양 T11TS 및 사람의 T11TS에 대한 항체를 함유하는 특이적 항체를 제조하는 방법.
- 제2항에 있어서, 토끼(rabit)를 면역시키는 방법.
- 적합한 종류의 동물을 균질한 양 T11TS로 면역시키고, 항 혈청중의 항체를 사람의 T11TS를 면역학적으로 측절하는 방법.
- 제4 항에 있어서, 토끼를 면역시키는 방법.
- 제2항 및 3항에 청구된 방법에 의해 수득할 수 있는 양 T11TS및 사람의 T11TS에 대한 항체를 함유하는 특이적 항체.
- 제4항 또는 5항에 청구된 방법에 의해 수득할 수 있는 60,000의 분자량을 갖는 사람의 양 T11TS당단백질.
- 면역조절제로서, 및 모노클로날 항체의 제조를 위한 제1항 및 7항에 청구된 사람 및/또는 양 T11TS 및 이의 변형체의 용도.
- 양 T11TS에 대한 모노클로날 항체를 이용하여 양의 적혈구의 분해생성물로부터 양 T11TS를 농축 시키고, 경우에 따라 겔 전기영동에 의해 정제시킴을 특징으로 하여, 제1항에 청구된 균질한 양 T11TS를 제조하는 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEP3639920.5 | 1986-11-22 | ||
DE19863639920 DE3639920A1 (de) | 1986-11-22 | 1986-11-22 | Homogenes schaf-t11ts als zwischenprodukt zur herstellung von menschlichem t11ts und dessen verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
KR880006359A true KR880006359A (ko) | 1988-07-22 |
Family
ID=6314535
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR870013131A KR880006359A (ko) | 1986-11-22 | 1987-11-21 | 사람의 tiits를 제조하기 위한 중간물질로서의 균일한 양 tiits 및 이의 용도 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0268995A3 (ko) |
JP (1) | JPS63150228A (ko) |
KR (1) | KR880006359A (ko) |
DE (1) | DE3639920A1 (ko) |
DK (1) | DK610387A (ko) |
IE (1) | IE873143L (ko) |
IL (1) | IL84549A0 (ko) |
PT (1) | PT86174B (ko) |
ZA (1) | ZA878695B (ko) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU660312B2 (en) * | 1991-06-06 | 1995-06-22 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | LFA-3-like protein, derivatives thereof, genes thereof and processes for preparing the same |
-
1986
- 1986-11-22 DE DE19863639920 patent/DE3639920A1/de not_active Withdrawn
-
1987
- 1987-11-19 EP EP87117058A patent/EP0268995A3/de not_active Withdrawn
- 1987-11-19 PT PT86174A patent/PT86174B/pt not_active IP Right Cessation
- 1987-11-20 JP JP62292225A patent/JPS63150228A/ja active Pending
- 1987-11-20 DK DK610387A patent/DK610387A/da unknown
- 1987-11-20 IE IE873143A patent/IE873143L/xx unknown
- 1987-11-20 IL IL84549A patent/IL84549A0/xx unknown
- 1987-11-20 ZA ZA878695A patent/ZA878695B/xx unknown
- 1987-11-21 KR KR870013131A patent/KR880006359A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DK610387A (da) | 1988-05-23 |
EP0268995A2 (de) | 1988-06-01 |
IE873143L (en) | 1988-05-22 |
PT86174A (de) | 1987-12-01 |
IL84549A0 (en) | 1988-04-29 |
EP0268995A3 (de) | 1990-04-18 |
PT86174B (pt) | 1990-08-31 |
ZA878695B (en) | 1988-05-20 |
DK610387D0 (da) | 1987-11-20 |
DE3639920A1 (de) | 1988-06-01 |
JPS63150228A (ja) | 1988-06-22 |
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