KR860005636A - 활성성분으로 스페르구알린(Spergualin)을 함유하는 주사제 조성물과 그 제조방법. - Google Patents

활성성분으로 스페르구알린(Spergualin)을 함유하는 주사제 조성물과 그 제조방법.

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Publication number
KR860005636A
KR860005636A KR1019860000125A KR860000125A KR860005636A KR 860005636 A KR860005636 A KR 860005636A KR 1019860000125 A KR1019860000125 A KR 1019860000125A KR 860000125 A KR860000125 A KR 860000125A KR 860005636 A KR860005636 A KR 860005636A
Authority
KR
South Korea
Prior art keywords
spergualin
preparation
active ingredient
composition containing
injection composition
Prior art date
Application number
KR1019860000125A
Other languages
English (en)
Other versions
KR920003331B1 (ko
Inventor
하마오 우메자와
신다로오 스즈끼
다까아끼 오오구마
후미히로 사도오
데루야 나까무라
Original Assignee
자이단호오진 비세이부쓰 가가꾸 겡뀨우가이
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 자이단호오진 비세이부쓰 가가꾸 겡뀨우가이 filed Critical 자이단호오진 비세이부쓰 가가꾸 겡뀨우가이
Publication of KR860005636A publication Critical patent/KR860005636A/ko
Application granted granted Critical
Publication of KR920003331B1 publication Critical patent/KR920003331B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
KR1019860000125A 1985-01-14 1986-01-11 활성성분으로 스페르구알린(Spergualin)을 함유하는 주사제 조성물과 그 제조방법. KR920003331B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP60003351A JPS61165322A (ja) 1985-01-14 1985-01-14 スパガリン類の注射用凍結乾燥製剤
JP60-3351 1985-01-14

Publications (2)

Publication Number Publication Date
KR860005636A true KR860005636A (ko) 1986-08-11
KR920003331B1 KR920003331B1 (ko) 1992-04-27

Family

ID=11554927

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860000125A KR920003331B1 (ko) 1985-01-14 1986-01-11 활성성분으로 스페르구알린(Spergualin)을 함유하는 주사제 조성물과 그 제조방법.

Country Status (10)

Country Link
US (2) US4710517A (ko)
EP (1) EP0188821B1 (ko)
JP (1) JPS61165322A (ko)
KR (1) KR920003331B1 (ko)
CN (1) CN1010279B (ko)
AT (1) ATE55246T1 (ko)
AU (1) AU589939B2 (ko)
CA (1) CA1263316A (ko)
DE (1) DE3579146D1 (ko)
IE (1) IE58220B1 (ko)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61129119A (ja) * 1984-11-13 1986-06-17 Microbial Chem Res Found 新規免疫抑制剤
ES2039213T3 (es) * 1986-04-04 1993-09-16 Microbial Chemistry Research Foundation Procedimiento para producir nuevos compuestos relacionados con espergualina.
CA1330650C (fr) * 1987-10-22 1994-07-12 Alain Huc Procede de stabilisation de phases lamellaires lipidiques hydratees, par exemple de liposomes, composition de phases lamellaires lipidiques hydratees, par exemple des liposomes, stabilisees par un emploi d'un support stabilisant a base d'atelocollagene et de glycosaminoglycannes, et utilisation en pharmacie ou en ...
FR2622104B1 (fr) * 1987-10-22 1990-03-30 Bioetica Sa Procede de stabilisation de phases lamellaires lipidiques hydratees, par ex. de liposomes, composition de phases lamellaires lipidiques hydratees, par ex. des liposomes, stabilisees par un emploi d'un support stabilisant a base d'atelocollagene et de glycosaminoglycannes et utilisation en pharmacie ou en cosmetologie
IE64346B1 (en) * 1988-01-19 1995-07-26 Moses Judah Folkman Growth inhibiting agent and the use thereof
AU626538B2 (en) * 1988-01-19 1992-08-06 Moses Judah Folkman Growth inhibiting agent and the use thereof
US5019562A (en) * 1988-01-19 1991-05-28 The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation Growth inhibiting agent and the use thereof
US5760015A (en) * 1988-01-19 1998-06-02 The Trustees Of The University Of Pennsylvania Cyclodextrin compounds and methods of making and use thereof
US5658894A (en) * 1989-04-23 1997-08-19 The Trustees Of The University Of Pennsylvania Compositions for inhibiting restenosis
US5637575A (en) * 1988-01-19 1997-06-10 The Trustees Of The University Of Pennsylvania Methods of inhibiting restenosis
US5002756A (en) * 1988-04-04 1991-03-26 Zaidanhojin Biseibutsu Kagakukenkyukai Method for relieving radiogenic or drug-induced side effects
EP0397542B1 (en) * 1988-12-02 1992-07-15 Coletica Stabilization process for hydrated lamellar phases
JPH03505334A (ja) * 1989-04-11 1991-11-21 イミユノバイオロジー・リサーチ・インスチチユート・インコーポレーテツド 凍結乾燥されたペプチド製剤
US5441944A (en) * 1989-04-23 1995-08-15 The Trustees Of The University Of Pennsylvania Substituted cyclodextrin sulfates and their uses as growth modulating agents
US5446030A (en) * 1991-09-19 1995-08-29 Weisz; Paul B. Prevention of hemolysis
US5424301A (en) * 1993-02-01 1995-06-13 Warner-Lambert Company Starch stabilized o-substituted tetrahydropyridine oxime cholinergic agents
WO1994022455A1 (en) * 1993-03-31 1994-10-13 The Trustees Of The University Of Pennsylvania Methods of affecting the growth of living tissue in mammals and compounds and compositions therefor
US5505715A (en) * 1994-02-25 1996-04-09 Bristol-Myers Squibb Company Iontophoretic transdermal delivery of deoxyspergualin compounds
CA2183917A1 (en) * 1995-09-26 1997-03-27 Xuebao Wang Preparation of optically active (s)-(-) and (r)-(+)- deoxyspergualin and novel intermediates thereof
ATE298582T1 (de) 1996-04-19 2005-07-15 Alpha Therapeutic Corp Verfahren zur inaktivierung von viren und lyophilisierung von blutproteinen
AU750207B2 (en) * 1997-06-13 2002-07-11 Cydex Pharmaceuticals, Inc. Polar drug or prodrug compositions with extended shelf-life storage and a method of making thereof
DE19932157A1 (de) * 1999-07-13 2001-01-18 Pharmasol Gmbh Verfahren zur schonenden Herstellung von hochfeinen Mikropartikeln und Nanopartikeln
US6815435B2 (en) * 2000-07-13 2004-11-09 Daiichi Pharmaceutical Co., Ltd. Pharmaceutical compositions containing DDS compounds
US20020146409A1 (en) * 2001-01-30 2002-10-10 Herring Steven W. Methods for stabilizing lyophilized blood proteins
TWI232102B (en) 2001-07-17 2005-05-11 Shionogi & Co A pharmaceutical formulation for injection

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54157818A (en) * 1978-06-02 1979-12-13 Tokyo Tanabe Co Injectionable preparation of chlorethylnitrosourea compound
JPS5748957A (en) * 1980-09-08 1982-03-20 Microbial Chem Res Found Novel antibiotic bmg 162-af2, its preparation and carcinostatic agent comprising it as active ingredient
JPS57185254A (en) * 1981-05-11 1982-11-15 Microbial Chem Res Found Novel carcinostatic substances and their preparation
JPS5862152A (ja) * 1981-10-08 1983-04-13 Microbial Chem Res Found Ｎ−〔４−（３−アミノプロピル）アミノブチル〕−２−（ω−グアニジノ脂肪酸アミド）−２−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法
JPS58198455A (ja) * 1982-05-17 1983-11-18 Microbial Chem Res Found （−）−１５−デオキシスパガリンおよびその製造法並びにその中間体
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
US4525299A (en) * 1983-05-10 1985-06-25 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai (-)-15-Deoxyspergualin, process for the preparation thereof, and intermediate of the same
JPS60185758A (ja) * 1984-03-02 1985-09-21 Microbial Chem Res Found フエニレン基を有するスパガリン関連化合物およびその製造法

Also Published As

Publication number Publication date
ATE55246T1 (de) 1990-08-15
KR920003331B1 (ko) 1992-04-27
AU5222486A (en) 1986-07-17
EP0188821A3 (en) 1987-08-12
CN1010279B (zh) 1990-11-07
EP0188821A2 (en) 1986-07-30
EP0188821B1 (en) 1990-08-08
JPS61165322A (ja) 1986-07-26
CA1263316A (en) 1989-11-28
JPH0413325B2 (ko) 1992-03-09
US4710517A (en) 1987-12-01
US4876244A (en) 1989-10-24
DE3579146D1 (de) 1990-09-13
AU589939B2 (en) 1989-10-26
IE860089L (en) 1986-07-14
IE58220B1 (en) 1993-08-11
CN86100157A (zh) 1986-08-27

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