KR850004393A - 경구 투여용 지효성(遲效性) 아세틸살리실산 제제 - Google Patents
경구 투여용 지효성(遲效性) 아세틸살리실산 제제 Download PDFInfo
- Publication number
- KR850004393A KR850004393A KR1019840008230A KR840008230A KR850004393A KR 850004393 A KR850004393 A KR 850004393A KR 1019840008230 A KR1019840008230 A KR 1019840008230A KR 840008230 A KR840008230 A KR 840008230A KR 850004393 A KR850004393 A KR 850004393A
- Authority
- KR
- South Korea
- Prior art keywords
- acetylsalicylic acid
- weight
- acid formulation
- oral administration
- sustained release
- Prior art date
Links
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title claims 9
- 229960001138 acetylsalicylic acid Drugs 0.000 title claims 9
- 239000000203 mixture Substances 0.000 title claims 5
- 238000009472 formulation Methods 0.000 title claims 4
- 238000013268 sustained release Methods 0.000 title claims 3
- 239000012730 sustained-release form Substances 0.000 title claims 3
- 238000000034 method Methods 0.000 claims 5
- 229920000881 Modified starch Polymers 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 2
- 230000000996 additive effect Effects 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 208000010110 spontaneous platelet aggregation Diseases 0.000 claims 2
- BSYNRYMUTXBXSQ-FOQJRBATSA-N 59096-14-9 Chemical compound CC(=O)OC1=CC=CC=C1[14C](O)=O BSYNRYMUTXBXSQ-FOQJRBATSA-N 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 230000000202 analgesic effect Effects 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 238000007908 dry granulation Methods 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (10)
- 아세틸살티실산 60%―90중량%, 전호화분 전분 8%―40중량% 및 첨가제 0―30중량%를 함유하는 지효성 아세틸살리실산 제제.
- 제1항에 있어서, 아세틸살리실산 70%―88중량%와 전호화분 전분 12―30중량%를 함유하는 아세틸살리실산 제제.
- 제1항 또는 제2항에 있어서, 질병 치료용으로 사용하는 아세틸살리실산 제제.
- 제1항 또는 제2항에 있어서, 통증, 염증 또는 혈소판 응집의 치료용으로 사용하는 아세틸살리실산 제제.
- 아세닐살리실산 60%―90중량%와 전호화분 진분에 8%―40중량% 및 첨가제 0―30중량%를 처리하여 정제 혼합물, 특히 과립상을 얻는 것을 특징으로 하는 지효성 아세틸살리실산제제의 제조방법.
- 제5항에 있어서, 건식 조립 방법을 행하는 것을 특징으로 하는 방법.
- 제6항에 있어서, 분말 상태로 전환시킴을 특징으로 하는 방법.
- 제6항에 있어서, 로울리으로 조립을 행함을 특징으로 하는 방법.
- 제1항 또는 제2항에 있어서 질병을 치료하기 위할 아세틸살리실산 제제의 사용.
- 제1항 또는 제2항에 있어서, 진통제 또는 소염제 또는 혈소판 응집영향제로서 아세틸살리실산 제제의 사용.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEP3346571.1 | 1983-12-23 | ||
DE3346571A DE3346571A1 (de) | 1983-12-23 | 1983-12-23 | Oral retardierte acetylsalicylsaeureformulierungen |
Publications (1)
Publication Number | Publication Date |
---|---|
KR850004393A true KR850004393A (ko) | 1985-07-15 |
Family
ID=6217790
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019840008230A KR850004393A (ko) | 1983-12-23 | 1984-12-21 | 경구 투여용 지효성(遲效性) 아세틸살리실산 제제 |
Country Status (12)
Country | Link |
---|---|
US (1) | US4601895A (ko) |
EP (1) | EP0146863A3 (ko) |
JP (1) | JPS60152411A (ko) |
KR (1) | KR850004393A (ko) |
AU (1) | AU3658984A (ko) |
DE (1) | DE3346571A1 (ko) |
ES (1) | ES8605676A1 (ko) |
GR (1) | GR82580B (ko) |
HU (1) | HU191738B (ko) |
IL (1) | IL73879A0 (ko) |
PT (1) | PT79701A (ko) |
ZA (1) | ZA8410045B (ko) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS615027A (ja) * | 1984-06-18 | 1986-01-10 | Sadahiro Nakano | 徐放性固形製剤 |
DE3508097A1 (de) * | 1984-07-21 | 1986-02-06 | Hoechst Ag, 6230 Frankfurt | Kombinationspraeparat aus xanthinderivaten und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung |
IT1191674B (it) * | 1986-03-07 | 1988-03-23 | Eurand Spa | Formulazioni per la preparazione di farmaci a rilascio prolungato adatte alla somministrazione per via orale |
GB8624213D0 (en) * | 1986-10-09 | 1986-11-12 | Sandoz Canada Inc | Sustained release pharmaceutical compositions |
US4855139A (en) * | 1987-01-20 | 1989-08-08 | Med. Fab (Lafayette), Inc. | Fungicidally active cellulosic textile compositions, or articles of manufacture |
US4904477A (en) * | 1987-07-08 | 1990-02-27 | American Home Products Corporation | Spray dried ibuprofen compositions |
US4857337A (en) * | 1988-05-24 | 1989-08-15 | American Home Products Corp. (Del) | Enteric coated aspirin tablets |
ZA942818B (en) * | 1993-04-23 | 1995-01-30 | Bio Technology General Corp | Method of enhancing thrombolysis. |
US5993860A (en) * | 1993-06-17 | 1999-11-30 | Venture Lending | NSADI delivery employing a powdered hydrocolloid gum obtainable from higher plants |
AU6403196A (en) * | 1995-06-30 | 1997-02-05 | Baylor University | Polyester/carboxylic acid composite materials |
JP4064476B2 (ja) * | 1996-03-29 | 2008-03-19 | エラワン ファーマスーティカル リサーチ アンドラボラトリー カンパニー リミテッド | 二酸化珪素を有する球状凝集した澱粉 |
IN186245B (ko) | 1997-09-19 | 2001-07-14 | Ranbaxy Lab Ltd | |
US6852337B2 (en) * | 1998-04-09 | 2005-02-08 | Roche Diagnostics Gmbh | Carvedilol-galenics |
WO2006061716A1 (en) * | 2004-12-09 | 2006-06-15 | Ragnar Ek | Pharmaceutical formulation comprising low crystallinity cellulose |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE737909C (de) * | 1940-11-19 | 1943-07-29 | Apothekerschaft Deutsche | Verfahren zur Beseitigung des Wasseranziehungsvermoegens und zur geschmacklichen Verbesserung arzneilich verwendbarer Stoffe |
US3034911A (en) * | 1959-03-25 | 1962-05-15 | Nat Starch Chem Corp | Tablet disintegrants |
FR280067A (ko) * | 1960-11-17 | |||
US3490742A (en) * | 1966-01-14 | 1970-01-20 | Staley Mfg Co A E | Compressed tablets |
US3622677A (en) * | 1969-07-07 | 1971-11-23 | Staley Mfg Co A E | Compressed tablets containing compacted starch as binder-disintegrant ingredient |
US3725556A (en) * | 1970-11-12 | 1973-04-03 | D Hanssen | Method of manufacturing rapidly disintegrating pharmaceutical tablets |
US4072535A (en) * | 1970-12-28 | 1978-02-07 | A. E. Staley Manufacturing Company | Precompacted-starch binder-disintegrant-filler material for direct compression tablets and dry dosage capsules |
US4328217A (en) * | 1972-12-29 | 1982-05-04 | Mead Johnson & Company | Bran tablet composition and process |
US3946110A (en) * | 1974-05-30 | 1976-03-23 | Peter, Strong Research And Development Company, Inc. | Medicinal compositions and methods of preparing the same |
US4086335A (en) * | 1975-10-29 | 1978-04-25 | Bruscato Frank N | Pharmaceutical tablets containing chitin as a disintegrant |
DE2708513C3 (de) * | 1977-02-26 | 1981-01-08 | C.H. Boehringer Sohn, 6507 Ingelheim | Wasserunlösliche, physiologisch unbedenkliche Masse, Verfahren zu ihrer Herstellung und ihre Verwendung |
US4198507A (en) * | 1978-11-13 | 1980-04-15 | Hoffmann-La Roche Inc. | Theophylline magnesium salicylate |
US4361545A (en) * | 1979-05-21 | 1982-11-30 | Rowell Laboratories, Inc. | Solid pharmaceutical formulations for slow, zero order release via controlled surface erosion |
US4264573A (en) * | 1979-05-21 | 1981-04-28 | Rowell Laboratories, Inc. | Pharmaceutical formulation for slow release via controlled surface erosion |
US4308251A (en) * | 1980-01-11 | 1981-12-29 | Boots Pharmaceuticals, Inc. | Controlled release formulations of orally-active medicaments |
US4339428A (en) * | 1980-08-18 | 1982-07-13 | Bristol-Myers Company | Capsule product containing high dosage of aspirin in powder or granulated form and alkaline tablet or pellet comprising magnesium carbonate, calcium carbonate and a magnesium dry component |
US4439453A (en) * | 1980-12-22 | 1984-03-27 | Monsanto Company | Directly compressible acetaminophen granulation |
US4401665A (en) * | 1981-04-14 | 1983-08-30 | Bristol-Myers Company | Sleep-aid composition containing an analgesic and diphenhydramine dihydrogencitrate, and method of use |
US4375468A (en) * | 1981-07-13 | 1983-03-01 | Verex Laboratories, Inc. | Constant order release aspirin composition and method of treating arthritis |
US4369308A (en) * | 1981-07-24 | 1983-01-18 | National Starch And Chemical Corporation | Low swelling starches as tablet disintegrants |
US4390545A (en) * | 1981-11-19 | 1983-06-28 | American Cyanamid Company | Combinations of agents which give enhanced anti-inflammatory activity |
US4525345A (en) * | 1981-12-24 | 1985-06-25 | Verex Laboratories, Inc. | Constant order release, solid dosage indomethacin formulation and method of treating arthritis and other inflammatory conditions |
US4539198A (en) * | 1983-07-07 | 1985-09-03 | Rowell Laboratories, Inc. | Solid pharmaceutical formulations for slow, zero order release via controlled surface erosion: expanded range |
US4520009A (en) * | 1983-11-28 | 1985-05-28 | Verex Laboratories, Inc. | Sustained released aspirin formulation |
US4551177A (en) * | 1984-04-23 | 1985-11-05 | National Starch And Chemical Corporation | Compressible starches as binders for tablets or capsules |
-
1983
- 1983-12-23 DE DE3346571A patent/DE3346571A1/de not_active Withdrawn
-
1984
- 1984-12-06 US US06/678,626 patent/US4601895A/en not_active Expired - Fee Related
- 1984-12-10 EP EP84115112A patent/EP0146863A3/de not_active Withdrawn
- 1984-12-12 AU AU36589/84A patent/AU3658984A/en not_active Abandoned
- 1984-12-17 ES ES538675A patent/ES8605676A1/es not_active Expired
- 1984-12-18 PT PT79701A patent/PT79701A/pt unknown
- 1984-12-19 JP JP59266499A patent/JPS60152411A/ja active Pending
- 1984-12-20 IL IL73879A patent/IL73879A0/xx unknown
- 1984-12-21 GR GR82580A patent/GR82580B/el unknown
- 1984-12-21 ZA ZA8410045A patent/ZA8410045B/xx unknown
- 1984-12-21 KR KR1019840008230A patent/KR850004393A/ko not_active IP Right Cessation
- 1984-12-21 HU HU844794A patent/HU191738B/hu unknown
Also Published As
Publication number | Publication date |
---|---|
JPS60152411A (ja) | 1985-08-10 |
ZA8410045B (en) | 1985-08-28 |
AU3658984A (en) | 1985-06-27 |
ES538675A0 (es) | 1986-04-01 |
PT79701A (en) | 1985-01-01 |
EP0146863A2 (de) | 1985-07-03 |
HUT36704A (en) | 1985-10-28 |
EP0146863A3 (de) | 1986-10-08 |
GR82580B (en) | 1985-04-23 |
US4601895A (en) | 1986-07-22 |
DE3346571A1 (de) | 1985-07-04 |
HU191738B (en) | 1987-04-28 |
ES8605676A1 (es) | 1986-04-01 |
IL73879A0 (en) | 1985-03-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
SUBM | Surrender of laid-open application requested |