KR850003397A - 치환된 피리딘의 제조방법 - Google Patents
치환된 피리딘의 제조방법 Download PDFInfo
- Publication number
- KR850003397A KR850003397A KR1019840000294A KR840000294A KR850003397A KR 850003397 A KR850003397 A KR 850003397A KR 1019840000294 A KR1019840000294 A KR 1019840000294A KR 840000294 A KR840000294 A KR 840000294A KR 850003397 A KR850003397 A KR 850003397A
- Authority
- KR
- South Korea
- Prior art keywords
- substituted pyridine
- preparing substituted
- formula
- catalyst
- triphenylphosphine
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 8
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 title 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1
- 150000003222 pyridines Chemical class 0.000 title 1
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical group [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims 4
- RIOQSEWOXXDEQQ-UHFFFAOYSA-N triphenylphosphine Chemical compound C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 RIOQSEWOXXDEQQ-UHFFFAOYSA-N 0.000 claims 4
- 239000003054 catalyst Substances 0.000 claims 3
- 229910052794 bromium Inorganic materials 0.000 claims 2
- 229910052801 chlorine Inorganic materials 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 229910052759 nickel Inorganic materials 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000012458 free base Substances 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical group CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 150000007530 organic bases Chemical class 0.000 claims 1
- 125000002524 organometallic group Chemical group 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (8)
- 일반식(II)의 화합물을 하나이상의 유기염기 및/또는 유기금속촉매량 존재하에 폐환시킴을 특징으로 하여 일반식(I)의 화합물을 제조하는 방법.상기식에서R1은 알킬, 아릴, 수소 또는 할로겐이고, R2는 Cl 또는 Br이고, R3는 Cl, Br 또는 F이다.
- 제1항에 있어서, R1이 메틸이고 R2및 R3가 Cl인 방법.
- 제1항에 있어서, R1이 에틸이고 R2및 R3가 Cl인 방법.
- 제1항에 있어서, 유리염기가 이소프로필아민인 방법.
- 제2항에 있어서, 촉매가 니켈다클로로비스(트리페닐포스핀)인 방법.
- 제1항에 있어서, 반응이 250℃ 내지 250℃에서 수행되는 방법.
- 제5항에 있어서, 그 온도가 70℃ 내지 250℃인 방법.
- 제1항에 있어서, 촉매가 유기아민 및 니켈디클로로비스(트리페닐포스핀)으로 이루어진 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/436,231 US4435573A (en) | 1982-10-25 | 1982-10-25 | Process for the preparation of substituted pyridines |
Publications (2)
Publication Number | Publication Date |
---|---|
KR850003397A true KR850003397A (ko) | 1985-06-17 |
KR900004040B1 KR900004040B1 (ko) | 1990-06-09 |
Family
ID=23731634
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019840000294A KR900004040B1 (ko) | 1982-10-25 | 1984-01-24 | 치환된 피리딘의 제조방법 |
Country Status (9)
Country | Link |
---|---|
US (1) | US4435573A (ko) |
EP (1) | EP0149291B1 (ko) |
JP (1) | JPS60152466A (ko) |
KR (1) | KR900004040B1 (ko) |
BR (1) | BR8400598A (ko) |
DE (1) | DE3471302D1 (ko) |
DK (1) | DK157014C (ko) |
HU (1) | HU194173B (ko) |
IL (1) | IL70659A (ko) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3167712D1 (en) * | 1980-08-27 | 1985-01-24 | Ciba Geigy Ag | Process for the preparation of chloropyridines substituted with methyl or trifluoromethyl groups |
US4577028A (en) * | 1981-10-20 | 1986-03-18 | Ciba-Geigy Corporation | 5-Haloalkyl-pyridines |
US4435573A (en) * | 1982-10-25 | 1984-03-06 | The Dow Chemical Company | Process for the preparation of substituted pyridines |
US5053516A (en) * | 1984-05-23 | 1991-10-01 | Ici Americas Inc. | Synthesis of 2-substituted-5-methylpyridines from methylcyclobutanecarbonitrile, valeronitrile and pentenonitrile intermediates |
US5084576A (en) * | 1985-12-20 | 1992-01-28 | The Dow Chemical Company | 2-hydrocarbyl-3,6-dichloropyridine compounds |
US5106984A (en) * | 1985-12-20 | 1992-04-21 | The Dow Chemical Company | 2-hydrocarbyl-3,6-dichloropyridines and their preparation |
IL86341A (en) * | 1988-05-11 | 1992-02-16 | Pamol Ltd | Preparation of polychloropyridine derivatives and intermediates therefor |
US4996323A (en) * | 1989-05-12 | 1991-02-26 | The Dow Chemical Company | Process for the preparation of 3,5,6-trichloropyridin-2-ol |
US5229519A (en) * | 1992-03-06 | 1993-07-20 | Reilly Industries, Inc. | Process for preparing 2-halo-5-halomethylpyridines |
CN113402452B (zh) * | 2021-07-29 | 2022-08-02 | 上海垚翀化工科技有限公司 | 一种制备2-氯-5-取代吡啶的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4245098A (en) * | 1978-12-05 | 1981-01-13 | Ciba-Geigy Corporation | Process for producing 2,3,5-trichloropyridine, 2,4,4-trichloro-4-formyl-butyronitrile as a novel compound and a process for producing it |
DE3167712D1 (en) * | 1980-08-27 | 1985-01-24 | Ciba Geigy Ag | Process for the preparation of chloropyridines substituted with methyl or trifluoromethyl groups |
ZA815906B (en) * | 1980-08-27 | 1982-08-25 | Ciba Geigy | Process for the production of chloropyridines substituted by methyl,trichloromethyl or trifluoromethyl groups |
US4435573A (en) * | 1982-10-25 | 1984-03-06 | The Dow Chemical Company | Process for the preparation of substituted pyridines |
-
1982
- 1982-10-25 US US06/436,231 patent/US4435573A/en not_active Expired - Lifetime
-
1984
- 1984-01-11 IL IL70659A patent/IL70659A/xx not_active IP Right Cessation
- 1984-01-16 DK DK017784A patent/DK157014C/da not_active IP Right Cessation
- 1984-01-16 EP EP84300241A patent/EP0149291B1/en not_active Expired
- 1984-01-16 DE DE8484300241T patent/DE3471302D1/de not_active Expired
- 1984-01-19 HU HU84202A patent/HU194173B/hu not_active IP Right Cessation
- 1984-01-20 JP JP59008402A patent/JPS60152466A/ja active Granted
- 1984-01-24 KR KR1019840000294A patent/KR900004040B1/ko not_active IP Right Cessation
- 1984-02-07 BR BR8400598A patent/BR8400598A/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0149291A1 (en) | 1985-07-24 |
IL70659A (en) | 1987-08-31 |
BR8400598A (pt) | 1985-09-17 |
HU194173B (en) | 1988-01-28 |
JPS60152466A (ja) | 1985-08-10 |
KR900004040B1 (ko) | 1990-06-09 |
DK17784D0 (da) | 1984-01-16 |
DK157014B (da) | 1989-10-30 |
EP0149291B1 (en) | 1988-05-18 |
HUT36803A (en) | 1985-10-28 |
US4435573A (en) | 1984-03-06 |
DK17784A (da) | 1985-07-17 |
DE3471302D1 (en) | 1988-06-23 |
DK157014C (da) | 1990-03-26 |
JPH0518827B2 (ko) | 1993-03-15 |
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A201 | Request for examination | ||
G160 | Decision to publish patent application | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
LAPS | Lapse due to unpaid annual fee |