KR850001185A - 프로판-2-올 유도체의 제조방법 - Google Patents

프로판-2-올 유도체의 제조방법 Download PDF

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Publication number
KR850001185A
KR850001185A KR1019840004048A KR840004048A KR850001185A KR 850001185 A KR850001185 A KR 850001185A KR 1019840004048 A KR1019840004048 A KR 1019840004048A KR 840004048 A KR840004048 A KR 840004048A KR 850001185 A KR850001185 A KR 850001185A
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KR
South Korea
Prior art keywords
propan
derivative
general formula
producing
preparing
Prior art date
Application number
KR1019840004048A
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English (en)
Inventor
쉬카네더(외 5) 헬뭇
Original Assignee
원본미기재
루드빅 호이만 운트 콤파니 게엠베하
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 원본미기재, 루드빅 호이만 운트 콤파니 게엠베하 filed Critical 원본미기재
Publication of KR850001185A publication Critical patent/KR850001185A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

내용 없음

Description

프로판-2-올 유도체의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 필요에 따라 생리적으로 받아들일 수 있는 염으로 전환되는 일반식(I)의 프로판-2-올 유도체의 제조방법에 있어서, 일반식(II)의 프로판-2-올 아민을 일반식(III)의 디아디아졸 유도체와 반응시켜 일반식(V)의 프로판-2-올 유도체를 형성시킨 후, 얻어진 일반식(V)의 프로판-2-올 유도체를 알코올성 암모니아 수용액과 반응시켜 일반식(I)의 화합물을 형성시킴을 특징으로하는 프로판-2-올 유도체의 제조방법.
    (이 식에서 R은
  2. 필요에 따라 생리적으로 받아들일 수 있는 염으로 전환되는 일반식(I)의 프로판-2-올 유도체의 제조방법에 있어서, 일반식(II)의 프로판-2-올 아민을 일반식(IV)의 시클로부텐디온 유도체와 반응시켜 일반식(VI)의 프로판-2-올 유도체를 형성시킨 후, 얻어진 일반식(VI)의 프로판-2-올 유도체를 알코올성 암모니아 수용액과 반응시켜 일반식(I)의 화합물을 형성시킴을 특징으로하는 프로판-2-올 유도체의 제조방법.
    (이 식에서 R은
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019840004048A 1983-07-22 1984-07-11 프로판-2-올 유도체의 제조방법 KR850001185A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3326545.3 1983-07-22
DE19833326545 DE3326545A1 (de) 1983-07-22 1983-07-22 Propan-2-ol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
KR850001185A true KR850001185A (ko) 1985-03-16

Family

ID=6204708

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840004048A KR850001185A (ko) 1983-07-22 1984-07-11 프로판-2-올 유도체의 제조방법

Country Status (16)

Country Link
US (1) US4599346A (ko)
EP (1) EP0132541A3 (ko)
JP (1) JPS6042375A (ko)
KR (1) KR850001185A (ko)
AR (1) AR242380A1 (ko)
AU (1) AU560038B2 (ko)
DE (1) DE3326545A1 (ko)
DK (1) DK290584A (ko)
ES (1) ES8504160A1 (ko)
GR (1) GR82256B (ko)
HU (1) HU192038B (ko)
IL (1) IL72179A0 (ko)
NZ (1) NZ208968A (ko)
PT (1) PT78923B (ko)
YU (1) YU123084A (ko)
ZA (1) ZA844651B (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR033779A1 (es) * 2001-06-08 2004-01-07 Astrazeneca Ab Compuestos utiles en la enfermedad de reflujo
DE60303167T2 (de) 2002-09-25 2006-09-14 Daiso Co., Ltd. Verfahren zur Herstellung von Glycidylphthalimid
WO2004037815A1 (ja) * 2002-10-28 2004-05-06 Kaneka Corporation 光学活性ｎ−（２，３−エポキシプロパンー１−イル）フタルイミドの製造法
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL189197C (nl) * 1979-09-04 1993-02-01 Bristol Myers Squibb Co 3,4-digesubstitueerde-1,2,5-thiadiazool-1-oxiden en 1,1-dioxiden, bereiding daarvan alsmede farmaceutische preparaten.
US4390701A (en) * 1981-05-18 1983-06-28 Bristol-Myers Company 1-Amino-2-[3-(3-piperidinomethylphenoxy)propylamino]cyclobutene-3,4-dione
DE3275291D1 (en) * 1981-07-24 1987-03-05 Glaxo Group Ltd Heterocyclic derivatives
US4411899A (en) * 1981-12-21 1983-10-25 Merck & Co., Inc. Substituted derivatives of amino alkane diols as gastric secretion inhibitors
DK317283A (da) * 1982-07-08 1984-01-09 Glaxo Group Ltd Fremgangsmaade til fremstilling af thiadiazolderivater
FI832520L (fi) * 1982-07-12 1984-01-13 Bristol Myers Co Farmaceutiska foerfaranden och sammansaettningar
US4521625A (en) * 1982-10-02 1985-06-04 Smith Kline & French Laboratories Limited Dioxocyclobutene compounds

Also Published As

Publication number Publication date
EP0132541A2 (de) 1985-02-13
PT78923B (de) 1986-06-02
DK290584D0 (da) 1984-06-13
GR82256B (ko) 1984-12-13
ZA844651B (en) 1986-02-26
DK290584A (da) 1985-01-23
HU192038B (en) 1987-04-28
YU123084A (en) 1986-10-31
ES534479A0 (es) 1985-04-16
AR242380A1 (es) 1993-03-31
ES8504160A1 (es) 1985-04-16
AU2953684A (en) 1985-01-24
JPS6042375A (ja) 1985-03-06
US4599346A (en) 1986-07-08
HUT34964A (en) 1985-05-28
AU560038B2 (en) 1987-03-26
PT78923A (de) 1984-08-01
DE3326545A1 (de) 1985-01-31
IL72179A0 (en) 1984-10-31
EP0132541A3 (de) 1985-09-25
NZ208968A (en) 1986-11-12

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WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid