KR840004055A - 진통 및 소염의 효능을 갖는 화합믈의 제조방법 - Google Patents

진통 및 소염의 효능을 갖는 화합믈의 제조방법 Download PDF

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Publication number
KR840004055A
KR840004055A KR1019830001230A KR830001230A KR840004055A KR 840004055 A KR840004055 A KR 840004055A KR 1019830001230 A KR1019830001230 A KR 1019830001230A KR 830001230 A KR830001230 A KR 830001230A KR 840004055 A KR840004055 A KR 840004055A
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KR
South Korea
Prior art keywords
compound
analgesic
inflammatory
formula
efficacy
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KR1019830001230A
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English (en)
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KR880002287B1 (ko
Inventor
이. 베이터맨 닐
Original Assignee
알.피 세리 코오포레이숀
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Publication of KR840004055A publication Critical patent/KR840004055A/ko
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Publication of KR880002287B1 publication Critical patent/KR880002287B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/90—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified hydroxyl and carboxyl groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Emergency Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

내용 없음

Description

진통 및 소염의 효능을 갖는 화합믈의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (7)

  1. 아세틸 살리실산 유도체를 다음 일반식(Ⅲ)의 모노글리콜 에스테르와 반응시켜 다음 일반식(Ⅰ)의 화합물을 제조하는 방법.
    [식중, R 및 R1은 탄화수소기이다.]
  2. 다음 일반식(Ⅰ)의 화합물.
    [식중, R 및 R1은 탄화수소기]
  3. 제2항에 있어서, R이 C1-15알킬인 화합물.
  4. 제3항에 있어서, 알킬 그룹이 직쇄 알킬인 화합물.
  5. 제4항에 있어서, 직쇄 알킬 그룹이 C7-11인 화합물.
  6. 제2항에 있어서, R1이 저급 알킬 그룹인 화합물.
  7. 제6항에 있어서, R1이 메틸, 에틸 또는 프로필 그룹인 화합물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019830001230A 1982-03-24 1983-03-24 아세틸살리실산 글리콜에스테르 화합물 및 그의 제조방법 KR880002287B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPF3285 1982-03-24
AUPF328582 1982-03-24
AU3285 1995-05-31

Publications (2)

Publication Number Publication Date
KR840004055A true KR840004055A (ko) 1984-10-06
KR880002287B1 KR880002287B1 (ko) 1988-10-22

Family

ID=3769424

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830001230A KR880002287B1 (ko) 1982-03-24 1983-03-24 아세틸살리실산 글리콜에스테르 화합물 및 그의 제조방법

Country Status (8)

Country Link
EP (1) EP0094738B1 (ko)
KR (1) KR880002287B1 (ko)
AT (1) ATE23859T1 (ko)
CA (1) CA1176644A (ko)
DE (1) DE3367916D1 (ko)
DK (1) DK534283A (ko)
NO (1) NO834296L (ko)
WO (1) WO1983003411A1 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7790153B2 (en) 1994-04-12 2010-09-07 Research Development Foundation Method of treating rheumatoid arthritis using orally administered type one interferons
AU6708896A (en) * 1995-07-27 1997-02-26 Cal International Limited Cardioactive aspirinates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2151185A (en) * 1936-01-16 1939-03-21 Carbide & Carbon Chem Corp Esters of glycol monoesters and acylated hydroxy acids
US2070240A (en) * 1936-05-09 1937-02-09 Ruben Samuel Therapeutic compound
US3012064A (en) * 1957-03-28 1961-12-05 Monsanto Chemicals Preparation of monoesters of polyhydric alcohols
US3644424A (en) * 1969-10-16 1972-02-22 Schering Corp Glyceryl acetylsalicylate and its analgesic anti-inflammatory use
US3652665A (en) * 1970-04-20 1972-03-28 Merck & Co Inc Halo-phenoxy salicylic acids
US3988446A (en) * 1974-11-07 1976-10-26 Abbott Laboratories Glycerides with anti-inflammatory properties
US4046887A (en) * 1976-10-28 1977-09-06 Abbott Laboratories Glycerides with anti-inflammatory properties
US4230842A (en) * 1976-10-28 1980-10-28 The Goodyear Tire & Rubber Company Hydrocarbon resin

Also Published As

Publication number Publication date
KR880002287B1 (ko) 1988-10-22
DK534283D0 (da) 1983-11-22
EP0094738A1 (en) 1983-11-23
DE3367916D1 (en) 1987-01-15
NO834296L (no) 1983-11-23
WO1983003411A1 (en) 1983-10-13
ATE23859T1 (de) 1986-12-15
EP0094738B1 (en) 1986-11-26
DK534283A (da) 1983-11-22
CA1176644A (en) 1984-10-23

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