KR840000564A - Method for producing cephalosporan acid - Google Patents

Method for producing cephalosporan acid Download PDF

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Publication number
KR840000564A
KR840000564A KR1019820002789A KR820002789A KR840000564A KR 840000564 A KR840000564 A KR 840000564A KR 1019820002789 A KR1019820002789 A KR 1019820002789A KR 820002789 A KR820002789 A KR 820002789A KR 840000564 A KR840000564 A KR 840000564A
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KR
South Korea
Prior art keywords
hydrogen
structural formula
producing
following structural
group
Prior art date
Application number
KR1019820002789A
Other languages
Korean (ko)
Other versions
KR840000176B1 (en
Inventor
다까시 외 4 가미야
Original Assignee
후지사와 유우기쪼로오
후지사와 야구힝 고오교오 가부시기 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 후지사와 유우기쪼로오, 후지사와 야구힝 고오교오 가부시기 가이샤 filed Critical 후지사와 유우기쪼로오
Priority to KR8202789A priority Critical patent/KR840000176B1/en
Publication of KR840000564A publication Critical patent/KR840000564A/en
Application granted granted Critical
Publication of KR840000176B1 publication Critical patent/KR840000176B1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

내용 없음No content

Description

세팔로스포란산의 제조방법Method for producing cephalosporan acid

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (13)

하기 구조식 (Ig) 혹은 그 염과 하기 구조식 (Ⅳ) 혹은 이것의 반응성 유도체로 반응시켜서 하기 구조식 (Ih) 혹은 그 염을 제조하는 방법.A method of producing the following structural formula (Ih) or a salt thereof by reacting the following structural formula (Ig) or a salt thereof with the following structural formula (IV) or a reactive derivative thereof. 상기식에서In the above formula R1은 R1 a가 수소, 아미노 혹은 보호된 아미노기,R 1 is R 1 a is hydrogen, amino or a protected amino group, R1 b와 R1 c는 각각 수소, 할로겐, 저급 알콕시 혹은 아릴티오이고, Z는 N 혹은 CH인 구조식R 1 b and R 1 c are each hydrogen, halogen, lower alkoxy or arylthio, and Z is N or CH 의 기 ; Group of; R2는 수소 혹은 저급 알콕시 ;R 2 is hydrogen or lower alkoxy; R3는 수소 혹은 저급 알킬 ;R 3 is hydrogen or lower alkyl; R5는 카르복시 혹은 그 유도체 ;R 5 is carboxy or a derivative thereof; R7은 알맞은 치환체를 지닐 수 있는 헤테로 시클릴-티오 ;R 7 is heterocyclyl-thio which may have appropriate substituents; X는 R6가 수소 혹은 알맞는 치환체를 지닐 수 있는 유기물인 구조식 ;의 기, 혹은 저급 알킬벤X is a structural formula wherein R 6 is hydrogen or an organic substance which may have a suitable substituent; Groups, or lower alkylbenes Y는 R7이 상기한대로인 구조식 ; H-R7의 (-R7)으로 치환될 수 있는 통상의 기임.Y is a structural formula wherein R 7 is as described above; A conventional group which may be substituted by (-R 7 ) of HR 7 . ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR8202789A 1978-11-13 1982-06-22 Process for preparing cephalosporanic acid KR840000176B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR8202789A KR840000176B1 (en) 1978-11-13 1982-06-22 Process for preparing cephalosporanic acid

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR7803425A KR820001324B1 (en) 1978-11-13 1978-11-13 Process for preparing cephalosporanic acid
KR8202789A KR840000176B1 (en) 1978-11-13 1982-06-22 Process for preparing cephalosporanic acid

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR7803425A Division KR820001324B1 (en) 1978-11-13 1978-11-13 Process for preparing cephalosporanic acid

Publications (2)

Publication Number Publication Date
KR840000564A true KR840000564A (en) 1984-02-25
KR840000176B1 KR840000176B1 (en) 1984-02-27

Family

ID=19209181

Family Applications (2)

Application Number Title Priority Date Filing Date
KR7803425A KR820001324B1 (en) 1978-11-13 1978-11-13 Process for preparing cephalosporanic acid
KR8202789A KR840000176B1 (en) 1978-11-13 1982-06-22 Process for preparing cephalosporanic acid

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR7803425A KR820001324B1 (en) 1978-11-13 1978-11-13 Process for preparing cephalosporanic acid

Country Status (1)

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KR (2) KR820001324B1 (en)

Also Published As

Publication number Publication date
KR840000176B1 (en) 1984-02-27
KR820001324B1 (en) 1982-07-23

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