KR840000482A - 시스틴 유도체의 제조방법 - Google Patents
시스틴 유도체의 제조방법 Download PDFInfo
- Publication number
- KR840000482A KR840000482A KR1019820003003A KR820003003A KR840000482A KR 840000482 A KR840000482 A KR 840000482A KR 1019820003003 A KR1019820003003 A KR 1019820003003A KR 820003003 A KR820003003 A KR 820003003A KR 840000482 A KR840000482 A KR 840000482A
- Authority
- KR
- South Korea
- Prior art keywords
- cystine derivatives
- preparing
- preparing cystine
- general formula
- derivatives
- Prior art date
Links
- LEVWYRKDKASIDU-IMJSIDKUSA-N cystine group Chemical class C([C@@H](C(=O)O)N)SSC[C@@H](C(=O)O)N LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 title claims 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 claims 1
- OJGDCBLYJGHCIH-UHFFFAOYSA-N bromhexine Chemical compound C1CCCCC1N(C)CC1=CC(Br)=CC(Br)=C1N OJGDCBLYJGHCIH-UHFFFAOYSA-N 0.000 claims 1
- 231100000252 nontoxic Toxicity 0.000 claims 1
- 230000003000 nontoxic effect Effects 0.000 claims 1
- UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 claims 1
- 231100000331 toxic Toxicity 0.000 claims 1
- 230000002588 toxic effect Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/29—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (4)
- 하기 일반식(Ⅱ)의 염화 시스틸을 2,4-디브로모-6-(n-메틸-N-시클로헥실-아미노메틸)-아닐린과 반응시킴을 특징으로 하는 하기 일반식(Ⅰ)의 시스틴 유도체 및 약학적으로 무독한 그의 산부 가염의 제조방법.
-
- 식중, R은 벤질옥시카르보닐 또는 토실기를 나타낸다.
- ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8120907 | 1981-07-07 | ||
GB8120907 | 1981-07-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR840000482A true KR840000482A (ko) | 1984-02-22 |
KR860001890B1 KR860001890B1 (ko) | 1986-10-24 |
Family
ID=10523063
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR8203003A KR860001890B1 (ko) | 1981-07-07 | 1982-07-06 | 시스틴 유도체의 제조방법 |
Country Status (26)
Country | Link |
---|---|
US (1) | US4438133A (ko) |
EP (1) | EP0069527B1 (ko) |
JP (1) | JPS5832860A (ko) |
KR (1) | KR860001890B1 (ko) |
AR (1) | AR231532A1 (ko) |
AT (1) | AT385505B (ko) |
AU (1) | AU551653B2 (ko) |
CA (1) | CA1188705A (ko) |
DE (1) | DE3225274A1 (ko) |
DK (1) | DK153025C (ko) |
ES (1) | ES513723A0 (ko) |
FI (1) | FI74456C (ko) |
FR (1) | FR2509298B1 (ko) |
GB (1) | GB2102792B (ko) |
GR (1) | GR76215B (ko) |
HU (1) | HU186087B (ko) |
IE (1) | IE53382B1 (ko) |
IL (1) | IL66074A0 (ko) |
IT (1) | IT1157284B (ko) |
MX (1) | MX7532E (ko) |
NO (1) | NO153494C (ko) |
NZ (1) | NZ200923A (ko) |
PT (1) | PT75167B (ko) |
SG (1) | SG80384G (ko) |
YU (1) | YU130382A (ko) |
ZA (1) | ZA824132B (ko) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6143968A (ja) * | 1984-08-08 | 1986-03-03 | Nippon Seifun Kk | 粉体の温度・水分を管理する装置 |
DE19851714A1 (de) * | 1998-11-05 | 2000-05-11 | Knoell Hans Forschung Ev | Amide des Cysteins als Inhibitoren der Farnesyltransferase |
JP4898185B2 (ja) * | 2005-10-24 | 2012-03-14 | Dtエンジニアリング株式会社 | ドアクローザー |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2723972A (en) | 1954-04-28 | 1955-11-15 | Du Pont | Homocysteinyl heterodipeptides |
DE2628911A1 (de) | 1976-06-28 | 1978-01-12 | Boehringer Ingelheim Lab | Neue schwefelhaltige n-benzylaminosaeuren und verfahren zu ihrer herstellung |
FR2423483A2 (fr) * | 1978-04-20 | 1979-11-16 | Boehringer Sohn Ingelheim | Procede de preparation de n-benzyl-aminoacides soufres |
-
1982
- 1982-06-07 GB GB08216479A patent/GB2102792B/en not_active Expired
- 1982-06-11 ZA ZA824132A patent/ZA824132B/xx unknown
- 1982-06-11 NZ NZ200923A patent/NZ200923A/en unknown
- 1982-06-15 YU YU01303/82A patent/YU130382A/xx unknown
- 1982-06-16 IL IL66074A patent/IL66074A0/xx not_active IP Right Cessation
- 1982-06-23 FI FI822255A patent/FI74456C/fi not_active IP Right Cessation
- 1982-06-24 NO NO822126A patent/NO153494C/no unknown
- 1982-06-25 AT AT0246782A patent/AT385505B/de not_active IP Right Cessation
- 1982-06-28 US US06/392,806 patent/US4438133A/en not_active Expired - Fee Related
- 1982-06-28 IT IT22067/82A patent/IT1157284B/it active
- 1982-06-29 AR AR289820A patent/AR231532A1/es active
- 1982-06-29 EP EP82303398A patent/EP0069527B1/en not_active Expired
- 1982-06-30 JP JP57114763A patent/JPS5832860A/ja active Granted
- 1982-06-30 PT PT75167A patent/PT75167B/pt not_active IP Right Cessation
- 1982-07-01 DK DK295782A patent/DK153025C/da not_active IP Right Cessation
- 1982-07-05 ES ES513723A patent/ES513723A0/es active Granted
- 1982-07-05 IE IE1624/82A patent/IE53382B1/en not_active IP Right Cessation
- 1982-07-05 CA CA000406576A patent/CA1188705A/en not_active Expired
- 1982-07-05 GR GR68643A patent/GR76215B/el unknown
- 1982-07-06 FR FR828211855A patent/FR2509298B1/fr not_active Expired
- 1982-07-06 DE DE19823225274 patent/DE3225274A1/de active Granted
- 1982-07-06 AU AU85642/82A patent/AU551653B2/en not_active Ceased
- 1982-07-06 KR KR8203003A patent/KR860001890B1/ko active
- 1982-07-07 HU HU822214A patent/HU186087B/hu not_active IP Right Cessation
- 1982-07-14 MX MX82101113U patent/MX7532E/es unknown
-
1984
- 1984-11-09 SG SG803/84A patent/SG80384G/en unknown
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